Basic Information

Insect: Rhodnius prolixus
Gene Symbol: Hr39
Assembly: None
Location: HiC:10964590-11050458[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.063 6.3e+02 -0.3 4.1 55 172 162 298 54 313 0.68

2 3 1.3e-09 1.3e-05 25.0 0.0 1 45 417 457 417 495 0.77

3 3 8.2e-69 8.2e-65 220.0 0.0 200 408 496 695 451 695 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.063	6.3e+02	-0.3	4.1	55	172	162	298	54	313	0.68
2	3	1.3e-09	1.3e-05	25.0	0.0	1	45	417	457	417	495	0.77
3	3	8.2e-69	8.2e-65	220.0	0.0	200	408	496	695	451	695	0.90

Sequence Information

Coding Sequence: ATGGAGCCAGGAGGAGGAGCAGCCGCACTCTCCTCGCTCAAGTGGCCCGAATCTCGAGGGGTGGTCACGTCTGGACAAGTCACTGTCACCACCATCAACATTCACCACAGCCCCCATGACAAAGAAGACAAGTATTATCCACCTCATTATAATGGTGgaCCAAGTAGTAAATGTTCTGTGTTAGTGAGTGGCGAACAGATGCATGTTGACGAGGATTCCTCAGCTGCTGATGCTGAAGTCAGCAACTTCACTAGTGAACCAGtgaatcttcgaaataaaaaaagagaagaatgcAGAAACTCTGTTGAAAGGCCAATGTCTTGGGAAGGTGAACTCTCGGACAGTGAAGTGACTGCAATCAAACCAgaaCCAGAAGAAACCGCCGTAGAAAACGCAGAATCCTCTGTTGACAATAAAACGGCCAATAAAGTCGGATCTCATGCGGAAGATGAGAAACcacaatcattaaaaataagtgaaggAGACAAATCAGTTGAAAATGTGAGGACAAATCAGTTTAATCCACAGTCTGAATTACCTCTTTTAATGGATAAGCTTCTTAGTAGCAGTAGTGGAGGAGGTTATAACGGTGTACTGAAAGGACCTGGACCAACTTCCAGTCCTGATTCGGCTGTATATTCATGTTATTCGCCAGCAGCGAGTCCTGTAACATCAAGACATATCTTGTCATCATCATCTGGAATTTCCAGTCCTTTTACTCCATCGTTGTCCAGGAACAATAGTGATGCATCCCAGTATGGTGGTTCCCAGCATTCATCATGCTACAGCCACAGTTATTCTTCAGTATCTGTGTCTCCAACTCAGTTTTCGCCAACTCATTCTCCCATCCAGGGCAGGCACATGCATAGACCAGGCTTCCCCTCACCTGTTCTCAATGCAAGAGGTGTGCCTGAATATCCTATGCAAGAAGAAGGAAATACTTTGGAAGATAAGTTTTCATCTTTAACCGCTGACATGGTGCAACATTCTACTGGATTAGCATCACCTGGCATAAGTAGACAACAGCTTATTAATAGCCCATGCCCTATTTGTGGTGATAAAATCTCTGGTTTTCATTATGGCATCTTCTCTTGCGAAAGCTGTAAAGGATTTTTCAAAAGAACTGTACAGAATCGTAAGAATTATGTCTGCCTTAGAGGTTCATCTTGCCCAGTTACTATAGCTACAAGGAAAAAATGTCCTGCTTGCCGTTTTGACAAATGCCTTAACATGGGAATGAAACTTGAAGcaATTCGAGAAGACAGAACTCGAGGTGGTAGAAGTACATACCAGTGCTCTTATACAGTACCTGCAGGATTGGTGGAACAGAAATGTGCAGAACTGACCGTACAGCCAAGATTAGAACAACAACCAGCCACAAATCTTGTACCCCCATTACTGCagGAAATAATGGAAGTAGAACATCTCTGGCAATACAACGAAGCGGATCCTAAACTAGTAGGACGTATTCCCAAACCTCCCAGTGGAAATCCAACAGATCTAATGGCCAATCTATGTAATATTGCTGACCACCGATTGTACAAGATTGTCAAATGGTGCAAGTCGCTacctctttttaaaaatatatctATCGATGACCAAACCTCGCTGCTCATAAATGCTTGGTgtgaattactattattttcatGTTGCTTCCGATCAATGTCTTCACCTGGTGAAATAAGAGTATCACTTGGCAAATGTATATCATTGACAGAAGCTAAAAATCTAGGACTCGGTCCGCCAATAGAACGAATGCTAAACTTTACTGATCATCTGCGTAGATTGCGAGTTGATCGCTATGAATACGTTGCCATGAAGGTCATCGTACTACTTTCTTCAgATACAAGCGAACTAAGGGAACCTGAAAAAGTGCGGGCATCACAAGAGAAAGCTTTACAAGCTTTGCAACACTATACTCTTGCCCATTATCCAGACATTCCGTCCAAATTCGGAGAACTTCTCCTCAGGATTCCAGACCTACAAAGGACCTgtcagGTTGGAAAAGAAATGTtgtcaataaaaagtaaagaaggCGAGGGCCCCAGCTTTAATCTCTTGATGGAGTTGCTTAGAGGAGACCATTAA
Protein Sequence: MEPGGGAAALSSLKWPESRGVVTSGQVTVTTINIHHSPHDKEDKYYPPHYNGGPSSKCSVLVSGEQMHVDEDSSAADAEVSNFTSEPVNLRNKKREECRNSVERPMSWEGELSDSEVTAIKPEPEETAVENAESSVDNKTANKVGSHAEDEKPQSLKISEGDKSVENVRTNQFNPQSELPLLMDKLLSSSSGGGYNGVLKGPGPTSSPDSAVYSCYSPAASPVTSRHILSSSSGISSPFTPSLSRNNSDASQYGGSQHSSCYSHSYSSVSVSPTQFSPTHSPIQGRHMHRPGFPSPVLNARGVPEYPMQEEGNTLEDKFSSLTADMVQHSTGLASPGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGSSCPVTIATRKKCPACRFDKCLNMGMKLEAIREDRTRGGRSTYQCSYTVPAGLVEQKCAELTVQPRLEQQPATNLVPPLLQEIMEVEHLWQYNEADPKLVGRIPKPPSGNPTDLMANLCNIADHRLYKIVKWCKSLPLFKNISIDDQTSLLINAWCELLLFSCCFRSMSSPGEIRVSLGKCISLTEAKNLGLGPPIERMLNFTDHLRRLRVDRYEYVAMKVIVLLSSDTSELREPEKVRASQEKALQALQHYTLAHYPDIPSKFGELLLRIPDLQRTCQVGKEMLSIKSKEGEGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00373210;
90% Identity: iTF_01479460;
80% Identity: iTF_01301679; iTF_01301655;