Basic Information

Insect: Rhimphoctona megacephalus
Gene Symbol: Baz2b
Assembly: GCA_963989365.1
Location: OZ022424.1:13550324-13596197[+]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 2.3e-21 1.8e-17 63.5 0.0 5 76 606 677 603 678 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	2.3e-21	1.8e-17	63.5	0.0	5	76	606	677	603	678	0.94

Sequence Information

Coding Sequence: ATGGAGAAGGAGAACTCCGCGTTGAGCGGAGGTGGCGGTGGCGAAAATACGGCAACGGTGCCGGGAGGAGGAGCCACCTCCGCCTCCGAAAAACTCCAGGCCGATCAGGCGAACCCTCTTCTCGACCCTAGCGCCCTTTTTGGTGCTTATTGGCCAAGAGGTGACAGTGCAGCGTCCTCTATTTTCGGTGGTATGCCAGGAGGTTATGGCCTCAGTGCTCATCACTTGCCCTCAGCTTATGCGATATTGGGCCGGGGTGGTACGGCGCCGGGTTTTGGTGGGCACACACCAACTTcggcaccaccaccaccaccaccaccatacACCCATGGGAGCCTTGGGACCCTCAGCGTTGCTGCCAGTCAAGCTGCTAGTTTAGgcATAAATCCGGCTAGCGCAGCATGGTGGACGATGGCCTCGCATTTAGCCGCTCAGGACTATCTCGCGAGGATACAGGGGGCTGCTGGACTACCGGGTTTTCCGCCTGGTGCCGAGAGCCTTTTACCACCCTATCCCGCCTCGTTACTTAATCCACCGTCCCACTCGTCCCACAAGTCCAGTAAGTCTAAGTCAAGCAAGAGTCATAAGACGTCAACGAGCAGTAGTAATTCGGGACCCCCGAGTAGTCACACAGGGAGTTTGGCTGTCAGTCAAGCTCCCATCACATCGTCAACTCATCATAGTACCTCGGCGAGTAGCAGTTGCAACACGCCAACCTCACAATCGCAAAATGTCGTCAGTGATCCCAGCAGTATTTTGGGGGGCGTACGTTTGCCACCGGACACGGAAATAATTAAGTACACATCGAGTATAGTAGGACCGAAAATTCCGGGGACAACAAATCGCGGACGGAAAAAAACGATATCGTTGGATTCGCCGAACGTGAGTGTACACGCGCCGCCTATACAGACGATGAGCGCGCATCAGACAAACACAACGACAACCTCGATGATGATCGAGCCGAGAAAGTACAATCGTACTTCCGGTTTGCAGAACGAGGTGAACGATTACAGGGAATCGATCGATCGCGTTGAGGTCATCAAATTGCCTGCCCATTCTACTAATGGCTCTGTACTTTCGGCACCGCCAATTTACACTACTTGCAACACCACCAACGCCAATCTCAATGTCAATGACTCTGATGCCCCACTCAATTTGTCCCTTAAACCGGCATCCACCAGCAGCAATTCACCAATTCCTGGCAGTCAACCTCTCAGCCAATTGAGCAATCTCAGCCACTCTTTACTCACATCCGACAGAACTTcTCGAAGAAAACCTGGTCCAAAACCAAGAAGAGTGCCCCAAAATTCAGCGTCGGTGCCGGCGTCGCCGAGTCCCTCGCTCGCACAACTTTTCGCGGCGGCCGATTCCCCGCAAAGGCCCAGCAGCGGAAGCGAAGAGAGCGAAAGCACGACGACGCATCACAAAGATGGCAGACCGAGAAATCTCGGTCGCGGGGTCTCAAAACCGAAGAAAAATACCGTCGCTTCGTTGCTCGCACAGAGCAGAGCTCTCGGAATAAAACCAACACCGACACTCGATCCTAACGCCCCCTTGTCTCATCAAGTCTCTTTACTCAGATCGAACATTCTCGCCGCCCAATTGCACGCCTCGGCGACCGGTCAAATCGATGAGAAAAATCAGCGCTCGTTGCAGGAGAAAATGAAGAACAAATTGCTCGAGGCTTCCGGTGAGGAAAGCAATATGGACGTAACGAGCGAAAGCGGAAGCAACACGGACGTCGTGACCGACACCGACGAGGACAATGCCGAGGGCACACCCAGCGCCAAAAGAAGAAAACTTAATCCCAGCGACAAGGACCTTCAGGTGCCCTTGGAACGGGGATGGAAAAGAGAGACGGTTATTAAGGGGCTTGGAAAAACAGGTGTCATTAAAGGCGACGTTTCGTATTATAGTCCTTGCGGCAAAACTTTCAGAAGCAGTCCCGATCTTTTAAagTTTCTGGAGCAGCAAAATCCTGCTGAATTGACAACGGCCAATTTTTCATTCTCATCGAGGTCGTTGGTCGGTGAATTTCTTCAGCCAACGATGGGCTTCGCTGAGGCTGAATTCGTGAGGTTGGGATCGCAGGAAGTTGCGAGAAGACTCGAGGAACTCAGAGCTGCCGGTGGCTTCAGAGACTCCAGACCCAATAATCAGTATGAAAGAGACAAACTCGCTTATgcgaaaaaactcgccaaggAAGAAGCTCAGAGACACAAAGAACAAGCGAGaTTAATAAAGGAGCAAGAAAAAACGGAGCGTCAGGAGGCGGTGAGGAGAGAACGTGAGTTGAGAAATCAGCAGCTTCTCGAGGGTCGAAAGAGGCTGGCATTCACGATCAAGCAGAAGATGAAGATAATTCAGGAGATCGAGAGAGGCAAGAGCAAGAGCGACGTTGCCAGGGAATTGGGTTTGGCGAGCAGCACAGTTGCGACGATATGGAAAAATCGTGTTAGCATCGCCGAGAGCTGGAGGAATCGTGACATTATGCAAACGCCCGAAACAATCGGTGAAATTGGTGAAACTTCACCGATTGTTCAAACTATGAAGAAAACGAGTCATCTCACAGCGTTACCGATCAATCAAACGGTCACGACCGTCGCGCCCAGTCTCGCACCGCCGATCGCGCCACTAGTCACTCCAACGATCGTTACGATTACTTTACCCACGCCACCGTCCGCGTCGCCACCCTCAACTATCGCCAATTCCTCCGCCGGAGTCGGCCAAATTTCATCTTCCATCGCCAACGCAACTTCCAATCTTTCAATTGATTTTTCCGGTGCTGCTAACTCTCCAACAATCGCCAATATCAACGCTATTTTAACGCAAGAACAAGAACAACtacatcaacaacaacaacaacaacaacaacaacaacaacaacaacaacaacttgTGGAGAACAACATCCAGCAGGCTCAGACCCAAACGCAAAATCAGGAACTGCTGGAGGCTCGAAAAAAACGACAAGAGGAGGTCGAGAAAATCCGGATGGAGGAACAACAACGAAAGCAACAGgAACGAGAGCTGAAGAGACAACAAGCAGTAATGTTGAAAGAGCAGATGTACATGCAGGAGCTCAGCAAGCAGCGCGAGATGCTCTACACCGTCGAGCTGgaACGTGAGCGAAGGCGACAACACATGGCACTCGTACGAGCTCTTGAGAATCGTCGAAAAatggaagaaagagaaagaaaacgatTGGAGGCTCGAGCCGAAAGAATTGCCAATAAAGAAAAACGCGCCGAGCAACGAAAAATGGAACTGGAACTGGTCGAACAGATCAGAAAACCGGTCGAAGACATGGAACTCACTGatcaCCGAGCTCTACCGAAAATAAAACGTTTGCCGGGTTTGAAACTCTCCGGTCAAGCGTTTTCGGACATCGTAATGGTTTTTGAGTTTTTACACAATTTTGGAGAAACTCTCggtttcgaTATGGAATCACTGCCAAGCCTAAAAAGTCTTCAGCTCGCGTTGTTGAATGACGAGGAAGCGGAGGAAGAAATGTTGTCAGTAATGACGCATCTTCTCGTGTGCGCGATCGAAGATCCAGGAATTCCTCAGCCTGCTCGTCACACGACAGGACTTGGCCAAAGTTTGCGTCAAGCTGACATAACTCACGCGAACATAAGCGAAGTTTTACGTATTTATTTGTACGCGAACGCGACCGGCGAGGTAAAAGCTCTTACCGGTGTTTGCCTCGAGCGCGAACGCGACAAAAGATTCGCGGATCATCATCAAAACGGTGGCGATTATCAGTCCACCGGATCCGGCAAAAATGCCCAATTTTATGAACATCTTCACAACAACGAGACTTGGAAAATGTCCGAAAGACTTCGCGACAAACCTTTCCTCGCTCTCAATCCAACACACAAATCACAAATGCTCGCTTTTCTTTGCAACGAATTGTTGCAAAACAAAGCTGTCATTCGACAGATCGAAGGAAGCCTCGAAAACGTTGCACAATTGAAAAAGGAACGTTTCATTCTTGACATGAAAATTCGAAAgCTCCGCCAATTACACAGCCGAAAAGTGAGGATGGAGGCGGTTGGAGTTATAATTAACAAAACTGGGGAGACGATCACGATCGACAAGAAAGAAGGCGAAGAAGGAAGCGAAGGAAACAACGCAGCGCCGACCGCCGCTGTCGACACGACTCCGACACCTGACGAATCAAATACTCACGACGAAACTCATGACGAAACGGAGGATATGTCGGAAAACGAGAGCGAGGGCACGCAGCCCGAAGAAgagGAAGACAAAAATTTATCGGGCGAAGAATTGGGCAAAAAATTGGACAAATTGTTGAAACAATCGGAGGAACAATTGCAAAAATTGAATCAATCGTCAAAGTCACTGAGGGCACACGTGTTCGGTCAAGATCGTTATTGGCGGCGTTATTGGGAACTGCCGTGTGCCGGTGGAATATTTGTTGAGGCGATGGAGAGCGCAGAGCCGGAGATTCTTGGCTTGCAAGCGGATTTGGATAAGAAATGGAAGGATCGAGTGATCGAAGAAGAAATGGAAAGTTCGGGGATGAAGAAAGAGGAGGAGAAAATGGAGAAGAAAATCGACACTGAAAATCGTGAGAACGAAGCGCCGAACGAAGTAAAACAATCGAATAAATTCAACGAAAAGGAGAATAACGACGAGATGAAAACTGAGGATAAACAGAAAATCGATCACGATGAAATAAACTGCAAAAAATCATTGCAAAATTCTCTGAACGATGAAACAACAAcgaaatcatcaaaaatcgatattaaaatggaaaataatgaGAATTCGATGACCGACGCCAAAACCAATGTCACCTCCGATGAAATAAAACAAGAAACCGAAATCGTTGCCATGGATGTTGACACGAAAATCGAAGACAACCTGAAAAAAGAACATTTGGAACATTCGCTTAAATGCGAAACTCCCAAAATCGTTGTCAAATTAATGGAAGACAAAATCATCGAGACTATGCCTAACGGCGATAAATTTAATCACATCAATAATTCACACAACCCCAAAGAAATTAATGGCACTTTCATGActgCCGAGAATACAGAGCCACATTGGTTCTCGATTCTTCCTCGCGAGACTTGCGACACTCCTGGACCAAGCACCAAACAAATATTCGGTATTGCCGAACCAACGGAATTGAGAATACCGATATTTCCACCTCCTGCTAGCCCGAATTACGATCGATGCGACAGTCCAGCTCCTCTCATTCTTACACAAGAAGAAGCTGTTCAATTGGAGTATTTGAAAATTCACGGTTTGCCACCTCCTGGCGAGGCGAAGCCTGTTCCAAGAGattatcgTTATGGCTGGTGGAGAATAAGGGACGTCGATACGTTCCAAGAGTTGCTCGAGCATTTGCATTCTCGTGGGGTACGAGAAAAAGAACTGAAAAGAACGACGTGGGCGACGATGGAATCGTTTTTGGCGGTCACAGGAAAAATTCACGTCGATCCTGGGAACGTTTCGGCGACGGAACTGGCGGCGATGTCGACAGACGACGCGGAATCGACGGCCATTCCGAGCCCCGATTTGCCCGAAGATTGGAGCGAACAAGTTGCTCTCAGAGTCGACGCTCAATTGCTCGAACAGGTAGAAGCTCTCGAGGACAAAGTTGCTAACGCGAGCATGCAAGTCAAAGGTTGGAAATTACCGCCGAGAGCCGGAACCGAAGAAGCCGATGAAATTGAAAAACTCAACGAAATGGAACAAGTTAATGCTGTAGAACAAGCCAGACAGAGGTTACTCTCCCTCGAAGCTGCCATCGAGAGAAGATACCTTAAACCTCCATTGGGCATTTGTACGGGAGATCCAAATCTAGCGGCTCTAAAAGCCGAACAAGCGGCAGCAGCGAACGCTAGTTTAAATTCGTCCGATCAAGGCGGACCCGCGCCGCCACCACAAGAAGAAACGACACCGCGAGGCTTGAACAATTGGCGAGAGGCGACCGCCCGCGCTCACACTTCCGCTCAACTGGCGATGGCGCTTTATATGCTCGAGGCTAGCATCGCATGGGACAAAAGCATCATGAAGGCTGTGAGTCTAACACCAGCTAGAAACTCGATCTGCGTCAAGCTACGAAACCGCTGCGtctcactcaaatctaccaatCAGTACAATCAGCTTTTGACTACTAATCAGTCCTCTAATTGTCAGTTTTGTCATAGCGGCGACAACGAAGACAAATTGTTGCTCTGCGATGGTTGTGATCGCGGATATCATACTTATTGCTTCCGtccaaaaatggaaaatattcccGATGGCGATTGGTACTGCCACGAGTGCATGAACAAGGCGACCGGTGAAAGAAACTGCTTAGTTTGCGGTAAAAGGGTCGGCAAAAACTTGGTCTTGTGCGAATTGTGTCCGAGAGCTTATCACACGGATTGTCACAATCCTGTAATGCCGAAGATACCGCGAGGCAAATGGTACTGTTCGAATTGTCACAGTAAGCAACCAAAGAAGAGGAACAGTACGAGGCGCAGTCACACCAAAGGCGGCGGGGGTGGGGGTGGAAATAGTGCCGGTGGAGGTGcgacagcagcagcagcagcagtagcTGCTGCTGCCACTGTTGGTGCTGGAGGCGCAAGTGGCGGCGGTGGCGGAGGAggcggaggaggaggaggaggaaatagCGGCGGTGGTGGCAGCGGAGGTGGAGCAGGAGGAGGAAGTGCAGGAAGTGGAGGAGGAAGTGGCGGAGGCGGCGGAGGAggaggtggaggaggaggaggaggaggtggtGGTGGAGGTGGAGGTGGTGGATCGATGACCCGAGATAGTGAGAGTTCCGATCATCCGCCAGCTAGTCCAACGCCATCGACGGCATCGAACACGCACGTCGAGGAGGTCAGTTCGTCGGAGCCACCAACGCCGACGGCATCCCCGAGGAAAGAGCCATCAGGAGCGAGCGTCGTGACCGGAAGCACTTCCGGAAGTGGCGCTAGTGGAGGAGGATCCGGAGGAGCCGGAAGTGGAAATAGCAACATCGGCGGAGCCTCGTCTGCTGGAACAACGACAACCGGAAGTGGCAACAACACTGGAACCGGAAACGCGACAAGCAGCGCAACCGGAAGCGGCAACGCAAGCAAAACATTGACGAAGAAACAACAGCGGGAGCTTGCACCTTGCAAGCTTCTCTTGGAACAATTGGAACAACAGGACGAAGCATGGCCATTTTTATTGCCAGTCAATACCAAACAATTCCCAACGTACAAGAAAATCATTAAAACTCCAATGGATCTCAGTACCATTAAGAAAAGACTTCAGGACAATGTATACAAGTCGCGGGACGAGTTCTGCGCGGACGTCCGGCAAATGTTCATCAACTGCGAGGTCTTCAACGAAGACGACAGTCCGGTTGGCAAAGCCGGCCACGGAATGCGAAGCTTTTTCGAAATGCGATGGACCGAAATCACAGGATCCCCGCCGCCCCCGCCCCCGACGCATAGCTGA
Protein Sequence: MEKENSALSGGGGGENTATVPGGGATSASEKLQADQANPLLDPSALFGAYWPRGDSAASSIFGGMPGGYGLSAHHLPSAYAILGRGGTAPGFGGHTPTSAPPPPPPPYTHGSLGTLSVAASQAASLGINPASAAWWTMASHLAAQDYLARIQGAAGLPGFPPGAESLLPPYPASLLNPPSHSSHKSSKSKSSKSHKTSTSSSNSGPPSSHTGSLAVSQAPITSSTHHSTSASSSCNTPTSQSQNVVSDPSSILGGVRLPPDTEIIKYTSSIVGPKIPGTTNRGRKKTISLDSPNVSVHAPPIQTMSAHQTNTTTTSMMIEPRKYNRTSGLQNEVNDYRESIDRVEVIKLPAHSTNGSVLSAPPIYTTCNTTNANLNVNDSDAPLNLSLKPASTSSNSPIPGSQPLSQLSNLSHSLLTSDRTSRRKPGPKPRRVPQNSASVPASPSPSLAQLFAAADSPQRPSSGSEESESTTTHHKDGRPRNLGRGVSKPKKNTVASLLAQSRALGIKPTPTLDPNAPLSHQVSLLRSNILAAQLHASATGQIDEKNQRSLQEKMKNKLLEASGEESNMDVTSESGSNTDVVTDTDEDNAEGTPSAKRRKLNPSDKDLQVPLERGWKRETVIKGLGKTGVIKGDVSYYSPCGKTFRSSPDLLKFLEQQNPAELTTANFSFSSRSLVGEFLQPTMGFAEAEFVRLGSQEVARRLEELRAAGGFRDSRPNNQYERDKLAYAKKLAKEEAQRHKEQARLIKEQEKTERQEAVRRERELRNQQLLEGRKRLAFTIKQKMKIIQEIERGKSKSDVARELGLASSTVATIWKNRVSIAESWRNRDIMQTPETIGEIGETSPIVQTMKKTSHLTALPINQTVTTVAPSLAPPIAPLVTPTIVTITLPTPPSASPPSTIANSSAGVGQISSSIANATSNLSIDFSGAANSPTIANINAILTQEQEQLHQQQQQQQQQQQQQQQLVENNIQQAQTQTQNQELLEARKKRQEEVEKIRMEEQQRKQQERELKRQQAVMLKEQMYMQELSKQREMLYTVELERERRRQHMALVRALENRRKMEERERKRLEARAERIANKEKRAEQRKMELELVEQIRKPVEDMELTDHRALPKIKRLPGLKLSGQAFSDIVMVFEFLHNFGETLGFDMESLPSLKSLQLALLNDEEAEEEMLSVMTHLLVCAIEDPGIPQPARHTTGLGQSLRQADITHANISEVLRIYLYANATGEVKALTGVCLERERDKRFADHHQNGGDYQSTGSGKNAQFYEHLHNNETWKMSERLRDKPFLALNPTHKSQMLAFLCNELLQNKAVIRQIEGSLENVAQLKKERFILDMKIRKLRQLHSRKVRMEAVGVIINKTGETITIDKKEGEEGSEGNNAAPTAAVDTTPTPDESNTHDETHDETEDMSENESEGTQPEEEEDKNLSGEELGKKLDKLLKQSEEQLQKLNQSSKSLRAHVFGQDRYWRRYWELPCAGGIFVEAMESAEPEILGLQADLDKKWKDRVIEEEMESSGMKKEEEKMEKKIDTENRENEAPNEVKQSNKFNEKENNDEMKTEDKQKIDHDEINCKKSLQNSLNDETTTKSSKIDIKMENNENSMTDAKTNVTSDEIKQETEIVAMDVDTKIEDNLKKEHLEHSLKCETPKIVVKLMEDKIIETMPNGDKFNHINNSHNPKEINGTFMTAENTEPHWFSILPRETCDTPGPSTKQIFGIAEPTELRIPIFPPPASPNYDRCDSPAPLILTQEEAVQLEYLKIHGLPPPGEAKPVPRDYRYGWWRIRDVDTFQELLEHLHSRGVREKELKRTTWATMESFLAVTGKIHVDPGNVSATELAAMSTDDAESTAIPSPDLPEDWSEQVALRVDAQLLEQVEALEDKVANASMQVKGWKLPPRAGTEEADEIEKLNEMEQVNAVEQARQRLLSLEAAIERRYLKPPLGICTGDPNLAALKAEQAAAANASLNSSDQGGPAPPPQEETTPRGLNNWREATARAHTSAQLAMALYMLEASIAWDKSIMKAVSLTPARNSICVKLRNRCVSLKSTNQYNQLLTTNQSSNCQFCHSGDNEDKLLLCDGCDRGYHTYCFRPKMENIPDGDWYCHECMNKATGERNCLVCGKRVGKNLVLCELCPRAYHTDCHNPVMPKIPRGKWYCSNCHSKQPKKRNSTRRSHTKGGGGGGGNSAGGGATAAAAAVAAAATVGAGGASGGGGGGGGGGGGGNSGGGGSGGGAGGGSAGSGGGSGGGGGGGGGGGGGGGGGGGGGGGSMTRDSESSDHPPASPTPSTASNTHVEEVSSSEPPTPTASPRKEPSGASVVTGSTSGSGASGGGSGGAGSGNSNIGGASSAGTTTTGSGNNTGTGNATSSATGSGNASKTLTKKQQRELAPCKLLLEQLEQQDEAWPFLLPVNTKQFPTYKKIIKTPMDLSTIKKRLQDNVYKSRDEFCADVRQMFINCEVFNEDDSPVGKAGHGMRSFFEMRWTEITGSPPPPPPTHS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01129346;
90% Identity: iTF_00266453;
80% Identity: -