Rneb006524.1
Basic Information
- Insect
- Rhaphigaster nebulosa
- Gene Symbol
- egg
- Assembly
- GCA_948150685.1
- Location
- OX411308.1:155554518-155586326[-]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 0.35 4.2e+03 -1.2 0.0 34 44 94 104 92 113 0.87 2 2 5e-11 6e-07 30.4 0.0 9 71 629 682 622 686 0.83
Sequence Information
- Coding Sequence
- ATGGAAGTAGTGGAAGTGAATGACGTTGTCTGTGTAGATGAGTCGGTTCCCTCTCCTTCTGTTGAAGTAGAAGCCTCAACCACTGATTCTGTTGAAACTGCCTGTGTTGATAGTCAAGAAGATGATGAATTATTAACTTTATACAAAGAATGTTTTCTTAAAGAACCAAGTTATTTTGTGGATCTTGACAAGGAGAAAGATTGCACCAAGAGGTCTTGTATTAATCTTCAGTGTGATACAGGGTCAGATTTTGTGGAACCACCTCGAATTGCAAGATCTTATTATTGTGCTCCTGAAGGAAGAAATTTAGCCATCTGTAAACCGTGTTTAAAAAATGTTTTGGGGTTCTATGAGGACTTGTTAGATAAATTGAGAAGAGGTATGCCAGTCAGTGATGCCAAGTTTCCTGCAGGAACAGAAGTTATCATAGTCGATGATGATGAGGAAGATATGCTCCAAAAAGAGCttaaaggaaaacaaaTTACTGGTTTAGAGAAAATAAAAGAAATTGCTCAAGAAGTAAAAAATGCATTGCCTACCATTTCTCTTCGATACAATATTGAAGGACAGATGGATAATAATTTGAATAGCTTGGAGTCAGAGATGAAACAATTAGAAGATAAATACAGAGATATTGAAGATGGCATAAATACGACTTACGAAAGTTTATTTCAGTCAATGAGGCAGCTTTATGACACCTATGCCCCAGAAAGAGAAGAAATGAATGAACTTGATTTACCTTATGAAGAATACAAGGAACCACCGATGAAGCCACTTCAGATACGTCCAGATGAAAATGATCTGATCATCACTGGGTTTCATCCTGAAAGTGGTCCACCAAATCTTCCACCATTTGGGGCAGTGGAGAAGCCTAAGGTAAAGGCTTTTGATAAAGTCTACGTGATGAAAGTATCAGCCTTTTCTGAATGGGTGCCTGCCGTTGTTGAAGAAGTTATGCCCCCGTCTCCTGAAAATCCTAAGGCAGTAGAATCTTACAAAGTAATGATAAATGCTGGAAAACCTTCTGCTTATCGGAAAGATGTCAGTTTGCAGTTGATCGCATGCTACAATGCACCTCCTGTCAGATTACCTGTCGGATCACGTGTTATATCTCGTTATGTTAACAGGTTAAAGAATACAGTTAAATTCTTCTCTGGCATGATTGCTGAGATGCCATCTCACATCAATAATTTTCGGTATTTGATATTTTTTGATGACGGACAAGCCCAGTATGGTACGCATGACTCTATTCGGCTGGTTTGTGAATCGAAAGCCAACATCTGGGACCATTTCAATCCGAAAGTACAACAGTTCATCAAGAGGTACTTGGTCACTTTTCCAGAGCGAGCGATGCTGAAAGTGAAGAATTTGGATTGTATCAAGACTGAACATAAAGGTATGTGGGTTAATGCTAGAGTTGTAGAAATAGATTGCTCTCTTGTCCATTTGGTGTTTCTCCACGACAAACACTCCGAGTGGCTGTACCGAGGATCCACTAGACTGTATCCGATGTACATCGGGCTACACAGAAAAGGGGCCCGGACGAGGGGAGGTTCTTTTGGAAGGCGCAAAGGCCCATACGTTCAATATGACGTGGTTCTTTCTGATGATGAAGACAATCAGAATGAAAGTGTACGCCCTGTCAGAGCCGTTGCAAGAAAGAGCAGCACTCGCCTGCCGGATTCGTACGATAATGAACGGAGGCTATATGACAGAAGGGCCGCCTCTAGGTTCCCGCCACAGCAGGATGATGGTGTAATTGAGCAAAGAGTACCATCTAAACTAGTTAAGCCAAAACTATTTCGTCCACATAAGTGTGACTCCAGTTGCACAGATTGGTTAATGACAAAAGAGGAAGACACCAAACTTTTGAATCCGTTGGTTGTTCCTGTTCTGTATGCATTTTCCAGAGAAACTGAAGTCCCAACAAATGCTATCAGTTATATCGCACCTTGCGGTAGGCGGTTGAGGAACATTGTTGAGGTCATGAATTATCTGACAGAGACCAATTTAAAATTGAGTTTGGATTTGTTTGATTTCGATCCTTGGGTGAACATATTTAATGAGTATGTTGTCTCTCCTGATATGGTTGTCATGGAGGACCTATCTTATGGCCAGGAGACTATGCCGATTGCTTGTGTCAATACAATCAACAGAAGTATTCCCACCTACATGGATTATATGACTAAACGGCGAGGTAGTGAAGGAGTGTATTTGAATTTGGAGCCTGGCTTCTTAGTGTGCTGCGATTGTACCGATAATTGTCAGGACAAATCAAAGTGTGCATGCTGGCAGTTGACTTTTGCAGAGAGTCAAGTCTTTCCCCCTGCTGCTGCTAAGAACCTTGACCAAGATTCCATCGGTTACCAATATAAGAGATTACCAAACATAATTAATACAGCCATCTACGAATGTAACAGTAGATGTAAATGCTGTGTAAAAACATGCTTGAACCGTGTTGTCCAACACCCACTGAAATTGAAACTACAACTTTTTATGACTAAAAACAAAGGCTGGGGTACAAGGTGCCTCAATGATATTCCAGCTGGTACTTTTGTCTGTGTTTATGTTGGTAACATTTACACTGAAGCAGTTGCAAATGAGGATGGAAAAATGTATGGGGATGAATATTTCGCTGAACTTGATTATATCGAAGTAGTGGAACAAAGTAAAGAGGGTTATGAGGAGTTTGTGGACCCTGAAGAATATTTGAATAATGAAAAAGCTTCTGAAGCACGTAGTAACAATGGAAATGGTCGCCATTCTGAAGATGAGTTTGAACCAAATGTATGGATTTCACCTTCTGAGTATAAGAAGAGCTCAGGAATGAACTTACGCAAGCGGTCAACAAGAAGTGTCAATTCAGATTTCAGTGATAGTGAAGATGAGGACAATTACGGACTAGATGATTCTGATGAGGAGCAGCAGGGTCCTGTCAACGTGGATGTATCAGATAATGACAGTGTCTCGTCATTACTAAAACCAAGCGTTAGGAATTTTTATGGCAAAGATGAATCTGTATATATAATGGATGCTAAAGCAGCTGGTAATATTGGACGATACCTTAATacAGGCAGAGAAGCAGACTGCCGAGAGCCAACTCTTTCAGAATGA
- Protein Sequence
- MEVVEVNDVVCVDESVPSPSVEVEASTTDSVETACVDSQEDDELLTLYKECFLKEPSYFVDLDKEKDCTKRSCINLQCDTGSDFVEPPRIARSYYCAPEGRNLAICKPCLKNVLGFYEDLLDKLRRGMPVSDAKFPAGTEVIIVDDDEEDMLQKELKGKQITGLEKIKEIAQEVKNALPTISLRYNIEGQMDNNLNSLESEMKQLEDKYRDIEDGINTTYESLFQSMRQLYDTYAPEREEMNELDLPYEEYKEPPMKPLQIRPDENDLIITGFHPESGPPNLPPFGAVEKPKVKAFDKVYVMKVSAFSEWVPAVVEEVMPPSPENPKAVESYKVMINAGKPSAYRKDVSLQLIACYNAPPVRLPVGSRVISRYVNRLKNTVKFFSGMIAEMPSHINNFRYLIFFDDGQAQYGTHDSIRLVCESKANIWDHFNPKVQQFIKRYLVTFPERAMLKVKNLDCIKTEHKGMWVNARVVEIDCSLVHLVFLHDKHSEWLYRGSTRLYPMYIGLHRKGARTRGGSFGRRKGPYVQYDVVLSDDEDNQNESVRPVRAVARKSSTRLPDSYDNERRLYDRRAASRFPPQQDDGVIEQRVPSKLVKPKLFRPHKCDSSCTDWLMTKEEDTKLLNPLVVPVLYAFSRETEVPTNAISYIAPCGRRLRNIVEVMNYLTETNLKLSLDLFDFDPWVNIFNEYVVSPDMVVMEDLSYGQETMPIACVNTINRSIPTYMDYMTKRRGSEGVYLNLEPGFLVCCDCTDNCQDKSKCACWQLTFAESQVFPPAAAKNLDQDSIGYQYKRLPNIINTAIYECNSRCKCCVKTCLNRVVQHPLKLKLQLFMTKNKGWGTRCLNDIPAGTFVCVYVGNIYTEAVANEDGKMYGDEYFAELDYIEVVEQSKEGYEEFVDPEEYLNNEKASEARSNNGNGRHSEDEFEPNVWISPSEYKKSSGMNLRKRSTRSVNSDFSDSEDEDNYGLDDSDEEQQGPVNVDVSDNDSVSSLLKPSVRNFYGKDESVYIMDAKAAGNIGRYLNTGREADCREPTLSE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00763857;
- 90% Identity
- iTF_00763857;
- 80% Identity
- -