Basic Information

Insect: Rhamphomyia laevipes
Gene Symbol: Hr39
Assembly: GCA_963920725.1
Location: OY987258.1:52888585-52892812[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.066 8.4e+02 0.2 3.3 48 139 23 121 7 156 0.47

2 5 0.53 6.8e+03 -2.8 9.6 67 144 198 293 179 335 0.37

3 5 3 3.8e+04 -11.1 17.0 33 154 241 371 235 501 0.59

4 5 6.5e-13 8.2e-09 36.4 0.1 1 142 568 696 568 708 0.65

5 5 2.7e-78 3.5e-74 251.8 0.5 200 408 707 908 697 908 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.066	8.4e+02	0.2	3.3	48	139	23	121	7	156	0.47
2	5	0.53	6.8e+03	-2.8	9.6	67	144	198	293	179	335	0.37
3	5	3	3.8e+04	-11.1	17.0	33	154	241	371	235	501	0.59
4	5	6.5e-13	8.2e-09	36.4	0.1	1	142	568	696	568	708	0.65
5	5	2.7e-78	3.5e-74	251.8	0.5	200	408	707	908	697	908	0.96

Sequence Information

Coding Sequence: ATGTCATCAACTGATATTGGGGATCCATCCTCAACAACAAATGTTACACCCACCGTTCTTACACAATtaacaacacaacaacaacaacaacaacaacaaaatggttCTGTTGCTGTCAATCAACATCATTCACAAAATATTCAACAACATACCACAACAATTATAAATCCACAACGAAATAATGTTTctgttacaaatataaaatgtgaaGATAGACTTAATTGTCGCCGTCCACCACAATTAGATACGCAGTCAGGAGGGCATCATGATTCTTCTGTACCATATAATGGTATTTCATCATCAAATATTagtagtaataattattttaatggtatTAGTTCGAATAGTACGACAACAACAACGACATCAGGTAATTGTGGTGGTATACGAATTGCTGTACCAAAACTTGAAGAATCTGATGAATCTGAAtcggaattaataaatattgaaaatttaaatgttaatcgtcgtataaataataatcaaaataaaaataatggtcCACGTCCAATGTCATGGGAAGGTGAATTATCAGAACCAGAAGGTGAATTAATGGATACAGataatagtataataaataatcataataatagtagtaataatcataataatcatcatcatcatcatgatAAACAAATTGACGAAACACAAATGTCAATTAAAGAAGAAGAATCTAAAActgaatttgatgaaattaCAATTGATGATACAATGTTAACAGCACAAATATATTCAACTagtttaaagaaatttcaacaacaacagcGACACCTtcagcaacagcaacaacaacagcaacacaataatgaaattattaatttaaaatatgaatcgaATAGTGGTAGTAGTAATGTACAAGGAGGAATTGGACCAATATcaattacaaatacaaatacaacaacaacatataaTACAACAGATCCAAATTTAACAAATAGTGGTTTAAATTCACCACTTTTAGCACGTTCAAAAATATGTTCAAATTTATTACCAGCTAATCCAAGTCCAGATTCAGCTATTCATTCCGTTTATACGCACAGTTCACCAAGTCAATCACCATTAACATCACGTCATGCACCATATACACCATCATTATCACGTAATAATAGTGATGCATCGCATAGCAGTTGTTATTCATATAGTTCAGAATTTAGTCCAACACATTCACCAATACAGGGTCGTCATAATATTTATGGTGGTAATAGCGGtggtaataatacaaatacaaattgtaataattttaataatggaaCTAATGTAACAACATCATTACATCATTCGGTATTATATCGTCCAATAcatgataatattattgaaaatggtATTCAGCATAATCATCGTCgtagtaataatgataatagtaatagtagttGTGGTGGTACACAATCAGCATCTAGTACAAGTGGTAGTACAACagatatattaattgaaaatgattcaTCTAGTATACCATCATCACCTGGTATATCACGACAACAACTTATAAATAGTCCATGTCCAATATGTGGTGATAAAATATCGGGTTTTCATTATGGTATATTTTCATGTGAATCGTGTAAAGGTTTCTTTAAACGTACCGTACAGAAtcgtaaaaattatgtttgtgtTAGGGGTGGTCCATGCCCGGTAACAATATCAACTAGAAAAAAATGTCCAGCATGTCGTTTTGATAAGTGCCTTGTTAAAGGTATGAAATTAGAAGCGATACGTGAAGATCGTACACGTGGTGGCCGATCAACATATCAATGTTCATATACATTACCAACACAATTAACAATGCCATCAGATAATAATAGTACAGCAAGTTTATTACAGCaggcaaataatcgaatgaatAGTTGTATTATTAAAACAGAATCTGGTATTAAAACAGATGgtaataattgtaatagtaataGTGGTTTTATTAAAACAGAAAATGATGTTGCGACTGGTAGTAGCAGTAATTTAGGACAGAAAATCAATACAGTACCACAACTGTTAcaggaAATCATGGATGTTGAACATCTATGGCAGTATAATGAATCGGAATTATCACGTTTAAATCAAACAACATCATCAAATACATCAACAgctaatttaacaacaaatgCACTACTGGCAAGTGCTGGTATATCATCAAATGGTGAAAATACAAATCCAGATTTAATAGCAACATTATGTAATGTTGCTGATCatcgtttatataaaattgttaaatggtGTAAAAGTTtaccattatttaaaaatatatctattgaTGATCAAATTTGTTTACTTATAAATTCATGGTGTGAATTACTTTTATTCTCTTGTTGTTTTCGTTCAATAGAAACACCaggtgaaataaaaatatcattaggTAAAACAATAACATTAATACAAGCTAAAACAAATGGATTGCATgctTGTGTTGAGCGAATGCTTAATTTGACTGATCATTTACGACGATTACGTGTTGATCGTTTTGAATATGTTGCCATGAAAGTAATTGTACTTTTACAATCTgATACATCAGAACTACGAGAACCAGTAAAAGTGAGACAAAGTCAGGAGAAAGCATTACAAGCTTTACAAAGTTATACATTAGCACATTATCCAGAAACACCATCAAAATTTGGTGAACTTTTATTACGAATACCAGAATTACAGAGAACATGTCAgcttgGCAAAGAAATGTTAACAATTAAATCAAAAGATGgtgaagattttaatttattaatggaaTTATTACGTGGAGAACATTGA
Protein Sequence: MSSTDIGDPSSTTNVTPTVLTQLTTQQQQQQQQNGSVAVNQHHSQNIQQHTTTIINPQRNNVSVTNIKCEDRLNCRRPPQLDTQSGGHHDSSVPYNGISSSNISSNNYFNGISSNSTTTTTTSGNCGGIRIAVPKLEESDESESELINIENLNVNRRINNNQNKNNGPRPMSWEGELSEPEGELMDTDNSIINNHNNSSNNHNNHHHHHDKQIDETQMSIKEEESKTEFDEITIDDTMLTAQIYSTSLKKFQQQQRHLQQQQQQQQHNNEIINLKYESNSGSSNVQGGIGPISITNTNTTTTYNTTDPNLTNSGLNSPLLARSKICSNLLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQGRHNIYGGNSGGNNTNTNCNNFNNGTNVTTSLHHSVLYRPIHDNIIENGIQHNHRRSNNDNSNSSCGGTQSASSTSGSTTDILIENDSSSIPSSPGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCPVTISTRKKCPACRFDKCLVKGMKLEAIREDRTRGGRSTYQCSYTLPTQLTMPSDNNSTASLLQQANNRMNSCIIKTESGIKTDGNNCNSNSGFIKTENDVATGSSSNLGQKINTVPQLLQEIMDVEHLWQYNESELSRLNQTTSSNTSTANLTTNALLASAGISSNGENTNPDLIATLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSIETPGEIKISLGKTITLIQAKTNGLHACVERMLNLTDHLRRLRVDRFEYVAMKVIVLLQSDTSELREPVKVRQSQEKALQALQSYTLAHYPETPSKFGELLLRIPELQRTCQLGKEMLTIKSKDGEDFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01297577;
90% Identity: iTF_01297577;
80% Identity: iTF_01297577;