Basic Information

Gene Symbol
-
Assembly
GCA_029963845.1
Location
JANEYF010001344.1:2976701-2988005[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 20 0.0021 0.44 13.1 1.6 2 23 10 32 10 32 0.95
2 20 0.074 15 8.3 1.0 1 19 161 179 161 181 0.97
3 20 2.3 4.7e+02 3.6 6.1 1 23 211 234 211 234 0.92
4 20 4 8.3e+02 2.8 0.1 5 20 244 259 243 261 0.91
5 20 0.01 2.1 11.0 0.6 1 23 267 290 267 290 0.92
6 20 3.9e-05 0.008 18.6 1.5 2 23 361 382 361 382 0.98
7 20 0.13 27 7.5 0.1 1 23 398 420 398 420 0.90
8 20 0.00065 0.13 14.8 0.4 2 23 424 445 423 445 0.96
9 20 0.00055 0.11 15.0 0.1 2 23 476 497 475 497 0.96
10 20 0.017 3.5 10.3 1.6 2 23 556 577 555 577 0.97
11 20 1.5e-05 0.003 19.9 6.5 1 23 613 635 613 635 0.98
12 20 0.068 14 8.4 0.8 3 23 652 672 652 672 0.94
13 20 0.00024 0.049 16.1 1.5 1 23 695 717 695 717 0.98
14 20 0.0014 0.28 13.7 0.9 2 23 732 754 731 754 0.96
15 20 0.0012 0.24 13.9 1.3 1 23 772 794 772 794 0.95
16 20 0.21 43 6.9 0.0 1 23 835 858 835 858 0.95
17 20 0.00015 0.032 16.7 2.0 2 23 869 890 869 890 0.97
18 20 6.1e-05 0.013 18.0 0.3 1 23 953 976 953 976 0.97
19 20 2.1e-05 0.0044 19.4 1.1 1 23 984 1006 984 1006 0.98
20 20 0.0078 1.6 11.3 0.1 1 23 1021 1044 1021 1044 0.94

Sequence Information

Coding Sequence
ATGGCTATAGGTGCCATGAATAATAGACAGTGTACTATTTGCAACAAACTGTTCAGTAGTTCCGGAAATAGAAGAAAACACGAGAAACAAATACATGGAAAACACCAGCCCGGAGCTGAAGTAGGTAGGAGGAGTCAAATGAATCAGGTTATGCTTACCAAATCTCTTGACGATCTTGCCAACCAGCAGGATAAACCAGTTGATCCATTAAATGCTCAAGAAAATGCCGAAGTAACTGAACCGCCCAGTGAGACTGAACAGCAAAAGATACAGTTTGCAGCCGGTTTAAAATTACTGCAAAGAAATTCCACACCAATCTCTTGCGAACCCCTTTCAAAAATAGAAATGagttatattgaaaaatgtaaagcAATGGCCTTGATGCATAAATCATTAGAATGTGCATGTCACAAAGTAGCACATCCGAATCTCAAAGGTTTACTCTCCCATCTCAGAGCTCTGAGAATATGGTTTCCAGTTTTTACATGCTACAATTGCATGATCACATTTACTGACCGATCTACCTTCACTAAACATAGTGTCAGATGTCCTAAAACTTCGTTAGAAACAATCATTAAGTTGAGTAACTTAAAGAAACGCAGCGAAGTTAAAACCAGGCTGtaccaaaatttcaaatgcaCTTCCTGCAAGTTTATGTACAGTTTTCATGATGACTATTGCAAACATGTTGATGAGGAGCATGTTGCTAATGAACCTCCCGTTATGTGTACCTGTGGCAGAGATTTCGACAACATGGAAGATTTCAAGGACCATGTTTACGTCAGCTGCCTAGTTGAGTACTATTgcgatatttgttttattaccaCCAAAACGTTGGACCAATTCCAAAAGCATGCCAGTGAGGTGCACGATAACTCCGAAGGGTTTATTTTATTGCAGGATGATAATTACAAGATGCGGAAACCATTCCATCACAAAGAAGCATCTGATGAAGCCGTTATTGTTACTGGAAAAAGAGAAAGAAGAATGTCTATCAAAGCTCCAATTTTGGAAAACGACGATGATGAAGACTTGCCACGGAAAGTTATTAATCCTGCAATATTATCAGCAAATTCAAGGGAATGTCCACTATGCGGCAAAGAATATTCAAGCCATAATAATATGATACGTCACTACAAAACTCATTTGGAAGTCACAGCAAGACCGGTCGAGACGTCAGATGATTCCTTCTACTCGTGTCCAGAATGTGGCGGCATGTACAACTATAGCGAGTGGCAAGTACATTTAGCAGAGAAACATGCACCTAAGACCTGTGGGGAATGTGGAAAGATCTTCCAATTCCAAAGTGAACTAGATCAACATAGGAGCGTTCATTTAAATCTTAAAGTATACAGAGATTCTAAAACACAGTCATATAAAACGACAATGATCAGTCCTGGATCTGAAGGAGGAGATGTTATGCTTATGTGTGAGGTATGTGACGTAATGTTTGGCACAAAAGAGGAACTGAAGGAACATAAACTGACTCATGAAGGAAATATCCCAGCTGTGGAACAGCCGGAAGAAGTGGTAGCCGAATTGAAGGATAGCAAATATTCGTGTATACcctgtaataaacattattccaGTTATGGGGGTATTTGGGACCATAACAAAAAGAAACATCCAGAAAAGAAAACTCCTTTCACTGACGAGTGGCCGAAGCAATGCAAGTTGTGCGACAAGGTGTGTGCTACGGGTGCAGCCTATTTTAGACATAAACAGATCCATGAAAAAGATAGAATAAATGAAGATAACGCTGATGTTATACCGATGAAAATGCCTATAATGAAGGCTAAGAGAGAAGCTGGCACGGAGGATGACGAACAGTCCTACCATACATGCAAACGTTGCTTTAAAGTGTTTTCTTCAAGGTACAATCTAAAGAATCATATGAAATCTCACGGTATAAATATGAATCCTACGAACAAAAAGATCACAAAGAAAGTTTGGTGCAACATATGTCATCAGTCATTTGCCAGTAACGAAATTTTGGCTAAGCACAAAGAGGAACATGGTGTAGATGAGATGCCTCAGCTAACGAACCAGGTTGAGGGATTAGATACTAAAGTACCATTTATCTTCACTTGCGACGTTTGTGTGATGACATTCACCACTAAAATGGCATTGAAGAAACATAAAGAGAAACACGCCCTAGAGCAGAAGCCTCCTGTCCAAAAGACATGCCAAGTTTACTGCAAATACTGTAAAATTGCTTTTGACTCGATCATTCTTTTAACGAAACACATGCACACTGAACATGAAGAGACTgccaaaccaaaaataaataagataaaagaaAAACCTCGACAGTTTGTTTGCACCATTTGCAAGAAACATTTCTTAACCTCTTCAGCATTGTCTACCCACATGGGTTGGCACAAGCGCAGTCCAAGTACGGGGGATAATAATAAACCCGCAaaagtattaaaacaaaacaaagttatcaataaaCTGGCTAATAATTTGAAGCCTAAACAGGAACCTATTGATCCTCCTCAGTTCCAATGCGCAACTTGCCTAGCCGAGTTTCCAAATGATACAGCCCTACAAGTTCACATTCTGGAAAAGCACCGCAGCGTCAGTGCGATCATGCTTATTCCCCGTTGTAACACTTGTAACAAAGATTTCAGCAACCAAGATGAGTACGAGACACACAAACGCTTGCATGACTTTTTGGAAAGGCAAAAGCAACATGAACAGCAGATGTTACTGCAACAACAAGAGGCAGAGGAGCAGCTTCCACTGATGGAGCAATCAGTATCGGTAGCAAAGGATATTACAGTAAAACAGCAACCAAAGCAAAAACCGCTAGCTCTACCACCAGCATCTATGCAGGCAAAGTTCATTAAGGGATTTCCCTGCAAGTATTGCAACGCGGCATTTAGCCGGGCTGACACACTGAGCGGGCATATTCGGCAGTTCCATAAGGAGTATGTGCTAAACGAGTTTAAATGCACGCAGTGCGATAGAGTGTTTGACAAGCAAAATTCTTTAAGTATTCATTTAAAGGTGCATGAGAAGCAGCGGTCGGTGGTGACTGCTCCGACTAAACCATTGTTCTCTTGTTCCATTTGTAGTATGGGCTTTGATTTACCCAAAGATCTGAGAGCACATACAATCAATGCGCATCCGTTCTGa
Protein Sequence
MAIGAMNNRQCTICNKLFSSSGNRRKHEKQIHGKHQPGAEVGRRSQMNQVMLTKSLDDLANQQDKPVDPLNAQENAEVTEPPSETEQQKIQFAAGLKLLQRNSTPISCEPLSKIEMSYIEKCKAMALMHKSLECACHKVAHPNLKGLLSHLRALRIWFPVFTCYNCMITFTDRSTFTKHSVRCPKTSLETIIKLSNLKKRSEVKTRLYQNFKCTSCKFMYSFHDDYCKHVDEEHVANEPPVMCTCGRDFDNMEDFKDHVYVSCLVEYYCDICFITTKTLDQFQKHASEVHDNSEGFILLQDDNYKMRKPFHHKEASDEAVIVTGKRERRMSIKAPILENDDDEDLPRKVINPAILSANSRECPLCGKEYSSHNNMIRHYKTHLEVTARPVETSDDSFYSCPECGGMYNYSEWQVHLAEKHAPKTCGECGKIFQFQSELDQHRSVHLNLKVYRDSKTQSYKTTMISPGSEGGDVMLMCEVCDVMFGTKEELKEHKLTHEGNIPAVEQPEEVVAELKDSKYSCIPCNKHYSSYGGIWDHNKKKHPEKKTPFTDEWPKQCKLCDKVCATGAAYFRHKQIHEKDRINEDNADVIPMKMPIMKAKREAGTEDDEQSYHTCKRCFKVFSSRYNLKNHMKSHGINMNPTNKKITKKVWCNICHQSFASNEILAKHKEEHGVDEMPQLTNQVEGLDTKVPFIFTCDVCVMTFTTKMALKKHKEKHALEQKPPVQKTCQVYCKYCKIAFDSIILLTKHMHTEHEETAKPKINKIKEKPRQFVCTICKKHFLTSSALSTHMGWHKRSPSTGDNNKPAKVLKQNKVINKLANNLKPKQEPIDPPQFQCATCLAEFPNDTALQVHILEKHRSVSAIMLIPRCNTCNKDFSNQDEYETHKRLHDFLERQKQHEQQMLLQQQEAEEQLPLMEQSVSVAKDITVKQQPKQKPLALPPASMQAKFIKGFPCKYCNAAFSRADTLSGHIRQFHKEYVLNEFKCTQCDRVFDKQNSLSIHLKVHEKQRSVVTAPTKPLFSCSICSMGFDLPKDLRAHTINAHPF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00886711;
90% Identity
-
80% Identity
-