Basic Information

Transcription Factor Domain

TF Family: PC4
Domain: PC4 domain
PFAM: PF02229
TF Group: Unclassified Structure
Description: This domain is found at the C-terminal end of Activated RNA polymerase II transcriptional coactivator p15 from humans, YdbC from Lactococcus lactis, and other PC4 family members. p15 has a bipartite structure composed of an N-terminal regulatory domain and a carboxy-terminal cryptic DNA-binding domain [1-4]. Activity is controlled by protein kinases that target the regulatory domain.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.094 7.3e+03 -1.4 0.1 2 15 8 21 7 25 0.82

2 3 4.8e-13 3.8e-08 34.8 0.4 1 39 105 143 105 148 0.97

3 3 2e-05 1.6 10.3 0.0 32 51 149 168 144 169 0.84

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.094	7.3e+03	-1.4	0.1	2	15	8	21	7	25	0.82
2	3	4.8e-13	3.8e-08	34.8	0.4	1	39	105	143	105	148	0.97
3	3	2e-05	1.6	10.3	0.0	32	51	149	168	144	169	0.84

Coding Sequence: ATGAGAAGAGTGGGGAGACTGAACATTGACAAAAGAACGTCAGTAAAAGTGATTTCGTTCAGAAGTGGTAACTTCAATCAGTTTACTCAGAACGAAAGAAAACAGCTATTATCATTTAAGAAATTCGTGATTAGTGTAGAGTGTACGAACAAAGCTAACGtGCTTCTTCAGAGTAATATAAGATGTCCGAATGTAAGGCCATCAAAAAAAGAGGAGAGCTCGAACTCGGgtccaaaaaatAAAGGACCAGTGAAGAAGCCAACCTCCGAAACAGAACAAAATGCAAGGGTATCAGGTGAAGAAGAGAATATGTGGGATTTAGGGAACAGTCACTTCATTAAATTAACAGAGTATGGAAAGAAATGGTATGTTAATATTCGTAAATTTTACAATACTGATGGCGCGCCCAAACCTGGAAAAGATGGTATTATCACAGACCTCGAATATATGTCTATGTCTACAGGTATTATGCTGCCCATAGAACAATGGCGGTTGCTTAAAGCCTATGTTAATGACATTGACGAAGCTATGCAGAAGAACAGTTag
Protein Sequence: MRRVGRLNIDKRTSVKVISFRSGNFNQFTQNERKQLLSFKKFVISVECTNKANVLLQSNIRCPNVRPSKKEESSNSGPKNKGPVKKPTSETEQNARVSGEEENMWDLGNSHFIKLTEYGKKWYVNIRKFYNTDGAPKPGKDGIITDLEYMSMSTGIMLPIEQWRLLKAYVNDIDEAMQKNS

Sequence clustering based on sequence similarity using MMseqs2