Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.017 2.8e+02 2.5 0.1 26 43 124 142 114 147 0.74

2 5 0.016 2.6e+02 2.6 0.0 22 45 150 173 141 180 0.84

3 5 0.0025 39 5.3 0.1 22 44 178 200 173 205 0.89

4 5 2.4e-05 0.39 11.7 0.1 21 51 205 235 201 236 0.87

5 5 0.00057 9.1 7.3 0.0 21 48 233 260 231 264 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.017	2.8e+02	2.5	0.1	26	43	124	142	114	147	0.74
2	5	0.016	2.6e+02	2.6	0.0	22	45	150	173	141	180	0.84
3	5	0.0025	39	5.3	0.1	22	44	178	200	173	205	0.89
4	5	2.4e-05	0.39	11.7	0.1	21	51	205	235	201	236	0.87
5	5	0.00057	9.1	7.3	0.0	21	48	233	260	231	264	0.89

Coding Sequence: ATGGATGAGGAGAGAGATGTGGATTTTCAGGCATCCTTGGAACCTGATATTATTATTGATGATGATTCGGGTGAAGAGAATCATTTTTATGAAAGCGATGGACAAATTAATATGGATAATCACCTTACGGACACTATACAAAAGCGTATTGGACCAGAAGTATCTCTTATACCAGTCAAAAGAAAATcgctcaaaattaaaatgttcagGAGTACATCACCCGAAGAAGAAAATGATGTGCAGGAAGTTAAAACGCGAAGATTTATACAAAGATCTCCTAGACAAACCGTAAGACTGATATCTAAAGAAGAACTTTCACAAGCCGAAAATGGTAACACTAATACAAAACGTAAATCGCTTCCTTTAGAAAAATGCCCtatatgtaaaaaattttttcggcGTATGAAAACCCATTTACAAAAACACGAAAATATTACAAGGGATCCGAATGATCCTTTAACGTGTAAATTTTGTATGAAAGCTTTTAACACCGGTAGCAATTTAAGTATACATATGCGTACTCATACGGGAGACAAACCGTACATATGCGAAGTTTGTACGAAAGGATTTGCGCAATCATGTAATTTAGTAAATCATATGCGTACTCACACGGGCGAACGACCGTTTAAATGTCCACATTGTGATCGCGCATTTACACAATCTGGAAATTTAAGTAATCATGTAAGATTACATACCGACGAAAAACCTTTCAAATGCCATTTTTGCGATAAAGCCTTTACACAATCGGGTAACCTTAATTCCCATATTAGAAACAatcataaatttacaaataatatcgGAAATGAACTGAGTAACAATGTTCAGTAG
Protein Sequence: MDEERDVDFQASLEPDIIIDDDSGEENHFYESDGQINMDNHLTDTIQKRIGPEVSLIPVKRKSLKIKMFRSTSPEEENDVQEVKTRRFIQRSPRQTVRLISKEELSQAENGNTNTKRKSLPLEKCPICKKFFRRMKTHLQKHENITRDPNDPLTCKFCMKAFNTGSNLSIHMRTHTGDKPYICEVCTKGFAQSCNLVNHMRTHTGERPFKCPHCDRAFTQSGNLSNHVRLHTDEKPFKCHFCDKAFTQSGNLNSHIRNNHKFTNNIGNELSNNVQ

Sequence clustering based on sequence similarity using MMseqs2