Basic Information

Insect: Rhagophthalmus giganteus
Gene Symbol: topi
Assembly: GCA_036326145.1
Location: JARFJA010000001.1:55872220-55876289[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00087 0.081 14.2 2.2 2 21 132 151 131 152 0.94

2 14 5.7e-06 0.00053 21.1 3.7 1 23 177 199 177 199 0.98

3 14 0.0094 0.87 11.0 2.0 2 23 206 227 206 227 0.95

4 14 0.011 1 10.7 0.1 2 20 246 264 245 266 0.93

5 14 3.9e-05 0.0036 18.5 1.0 2 23 340 361 339 361 0.97

6 14 0.034 3.2 9.2 0.3 1 22 367 388 367 388 0.94

7 14 0.36 33 6.0 2.6 2 21 404 423 403 427 0.83

8 14 0.00061 0.057 14.7 0.2 1 23 541 564 541 564 0.97

9 14 0.0088 0.82 11.0 0.1 1 23 568 590 568 590 0.97

10 14 7.7e-07 7.2e-05 23.8 2.4 1 23 596 618 596 618 0.98

11 14 0.028 2.6 9.5 0.2 1 23 624 649 624 649 0.96

12 14 0.66 61 5.2 2.7 1 23 655 677 655 677 0.85

13 14 2.2e-05 0.0021 19.2 0.3 3 23 685 705 683 705 0.98

14 14 3.4e-06 0.00032 21.8 0.5 1 23 711 734 711 734 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00087	0.081	14.2	2.2	2	21	132	151	131	152	0.94
2	14	5.7e-06	0.00053	21.1	3.7	1	23	177	199	177	199	0.98
3	14	0.0094	0.87	11.0	2.0	2	23	206	227	206	227	0.95
4	14	0.011	1	10.7	0.1	2	20	246	264	245	266	0.93
5	14	3.9e-05	0.0036	18.5	1.0	2	23	340	361	339	361	0.97
6	14	0.034	3.2	9.2	0.3	1	22	367	388	367	388	0.94
7	14	0.36	33	6.0	2.6	2	21	404	423	403	427	0.83
8	14	0.00061	0.057	14.7	0.2	1	23	541	564	541	564	0.97
9	14	0.0088	0.82	11.0	0.1	1	23	568	590	568	590	0.97
10	14	7.7e-07	7.2e-05	23.8	2.4	1	23	596	618	596	618	0.98
11	14	0.028	2.6	9.5	0.2	1	23	624	649	624	649	0.96
12	14	0.66	61	5.2	2.7	1	23	655	677	655	677	0.85
13	14	2.2e-05	0.0021	19.2	0.3	3	23	685	705	683	705	0.98
14	14	3.4e-06	0.00032	21.8	0.5	1	23	711	734	711	734	0.98

Sequence Information

Coding Sequence: ATGaataattctaataatataattctTAAGGTGCATCGAATAGACGAAAATGGCACAATAAGTTCTTATCAACATGAAGAAGATTTTATCACCCAAGAGGTGGTATCCAAAACCCAAATTTCtagtgaaaatttaaattttagctcCCACTACAATCAGAGTTATTCTATCGATAATAAAGTGAATCTAAGTTTTCGTTACTTGGAACCTGATGACCAATCTGTTACAATAGTAAAAATTGGAGGAGTGGATGACTTGAATCCTATGAATTATGCTACAGAAATAAGCACCGTATTGGATGATATTGGCaattgtaaatcatttattaacAGTAGTGTATCTCTAAATAAGTCGAAACGAGAAAGTAAAATCCCAAATATACCGACAATGATTAGATGCCAAAATTGTGATACAAATTTTCCAACTAAATATCAGTATCAACGACACCAGTGTGAATTTAATGCTGAAAAAGTGGTATTGAAAGCCGATGCAGACATCAAAGATATAGATAAAGGAATGCGAATTAAATATCATTGTACGACATGTGGGAAACAGTTTGtaagcaaaaataatttagagcGACATCAAACAAGTCACGACACAACACAAGAGAATGTATGCGAACACtgcaataaacaatttgtGAGCGAAAATCGGCTTCGGATTCATAAAGAAAATCATTGTAAAAAGGCTGGTgacatttcgaaattttatcgtAGTGATGTTACAGTTTGGAAATGTATGAAATGTAATCAAGTTTTTGCCACTCCCGCATCGGCAAAACGACATACCGAAAATTGCACGGAGATCATCAACGTTGATGTACCTCTCGAAGTTAAATCTGAAAATGAAATCAACGATAACAACGAGTTACTGATGCTAacacaagaaattaaaaacttatcaTCTGCGGCAcctgaaataataaatgaagatGTATCACGACAAATTTCTAATAATGTTAAATCCGATcctgttattttaaatgttgaaaaagttttgacagaattattgttacaatgtGAATATTGTAATCGTACTTATGCAGACAAGACTTTACTGTTGCTTCATCAAAAAAAACATACGACAGAAGTTAATTATGAATGTACAACTTGTAAGGAAATTTTTGATTCGTACACATCAGCAACAAAACATTGGATGACGAAATGTTCGGACGAAgctaatttgttttatcttcCAAAAATGACTTATTGCGAATATTGCGAACGTACTTTTAAATCGCACGAAATATTGTATACTCATAAGATTAAGAAAAAACATTATTCTCCGAAATTACATATAACAAAGAATTCCGAAGATGATAAAGAGAATGCACAAACAACAGGAAATAAAGATATTCTGGTGAAATTGATCGAAGACGTGTTGACCACAATGGACGTCTCGCTAAATTGCGACAAAAATGGTATAAACGAGAATAAAGAGAATGAAAATCCGAAAAATGTTGATCAAAGCGATGCCACTGCAACAGAAGATAATAAGCAAGTAAAAGAATTGGAAAGTCAAGAACCCGAACGAAAGAAAAGAGGTCGAAAACGAAAATGGCCAAAACAATCTAATAAATCTAAAGGAATACAGTTCACAGTCGAAAAGGGCTACAAGTATCAATGTGAACGATGTACGTTGGTTTTTAATGACGTCTCTGCATTAGAATCTCATCGTGAAAAGGAACATGCTTCTAATTTTTCATGTGAAGAATGTGgacaaGTGGTACACAGTGCAAAAGCATTAGTCATACATAGTAGAGCACATCAAAGCTTAAAGCCCTATGTGTGCGAACAGTGTGGCCGTAGTTATTCTCAAACTTCACATTTATGGCAACATATGCGTTTTCATCAagGTATCAAACCATTTGCCTGTCCGCACGAAGGTTGCGAAGCACGTTACACGATTCGTCCAGACTTGAAGGATCACATTAGAAAAGTTCATACCCGCGAAAGGCCCTTTAAATGTGTCGTttgtaataaatgtttcttAACAGGTTCTGTGTACTATCAACATCGCTTAATTCACACAAATGATCGTAGATACGGATGCGACATTTGTGAAAAGAGATTCTTCAGAGCCGATGCTTTAAATAATCATCGCAGAATCCATACCGATGAAAGGCCTTATCCTTGTGAAATTTGTGGAAGAGAATTTCGACAGAAAGGGGATAGAAATAAACATGTGCGTACACAGCATCCCGAATAA
Protein Sequence: MNNSNNIILKVHRIDENGTISSYQHEEDFITQEVVSKTQISSENLNFSSHYNQSYSIDNKVNLSFRYLEPDDQSVTIVKIGGVDDLNPMNYATEISTVLDDIGNCKSFINSSVSLNKSKRESKIPNIPTMIRCQNCDTNFPTKYQYQRHQCEFNAEKVVLKADADIKDIDKGMRIKYHCTTCGKQFVSKNNLERHQTSHDTTQENVCEHCNKQFVSENRLRIHKENHCKKAGDISKFYRSDVTVWKCMKCNQVFATPASAKRHTENCTEIINVDVPLEVKSENEINDNNELLMLTQEIKNLSSAAPEIINEDVSRQISNNVKSDPVILNVEKVLTELLLQCEYCNRTYADKTLLLLHQKKHTTEVNYECTTCKEIFDSYTSATKHWMTKCSDEANLFYLPKMTYCEYCERTFKSHEILYTHKIKKKHYSPKLHITKNSEDDKENAQTTGNKDILVKLIEDVLTTMDVSLNCDKNGINENKENENPKNVDQSDATATEDNKQVKELESQEPERKKRGRKRKWPKQSNKSKGIQFTVEKGYKYQCERCTLVFNDVSALESHREKEHASNFSCEECGQVVHSAKALVIHSRAHQSLKPYVCEQCGRSYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFKCVVCNKCFLTGSVYYQHRLIHTNDRRYGCDICEKRFFRADALNNHRRIHTDERPYPCEICGREFRQKGDRNKHVRTQHPE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00978686;
90% Identity: -
80% Identity: -