Basic Information

Gene Symbol
-
Assembly
GCA_036326145.1
Location
JARFJA010000057.1:197660-200203[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 4.7e-06 0.00044 21.3 0.1 1 23 170 192 170 192 0.98
2 12 0.48 45 5.6 2.0 1 23 198 220 198 220 0.96
3 12 2e-05 0.0019 19.3 3.1 1 23 226 248 226 248 0.98
4 12 0.00017 0.016 16.5 1.4 3 23 262 282 260 282 0.95
5 12 3.4e-05 0.0032 18.6 0.7 2 23 289 310 288 310 0.97
6 12 1.1e-06 0.0001 23.3 2.4 1 23 316 338 316 338 0.99
7 12 8e-06 0.00074 20.6 0.2 1 23 344 366 344 366 0.96
8 12 4.4e-06 0.00041 21.4 0.1 1 23 372 394 372 394 0.98
9 12 9.7e-07 9e-05 23.5 2.3 1 23 400 422 400 422 0.98
10 12 3.6e-06 0.00034 21.7 2.8 1 23 428 450 428 450 0.97
11 12 5.3e-07 4.9e-05 24.3 0.1 3 23 458 478 457 478 0.99
12 12 7.5e-08 7e-06 27.0 1.1 1 23 484 506 484 506 0.98

Sequence Information

Coding Sequence
atggaTATGAGCGTGTATCTTACCGCACCGATGCAGTTGGATAAGGTCTGTAGAGCGTGTTTGAGCGAAAAAGGCGACATGAGACCTTTATTTGGAGCCTGTTTGGACGAAATGTTAGTTTCGTTTGCTTCCATtcagGTTCAAGAAAACGACGGCTTACCAAATCTAATGTGTGTTCAGTGTGTTTTACAATGTAGCCGGGCATACACTTTCAAACAACAATGTGAAAAGTCGGACAATATTTTGAGGCAGTATATAAGTCAGGATTTTCAGGAACAACTACTGAAAGCAGAATCTACGGAAAATAAACAGCAGATTCAAGAGCACCTACAAATAACCGAAACTGTCATTCCCGACGATCTTCCCTCAGAATTAATCAACGTTAGTTACATCGAAGAtggcaatttcaaaattgaaGTTAAGGATTTATATAACATAGCCACCGCAGAACCTGAATCGGAAAAGAAAGACATAATTGTGAAGGAAGAAAAGTCACATAAACAAAAGTACCCTTGTTCGAAATGCGACGAGTCCTTTCCGCTTAAAGTTGACTTGAAGGTACATATGATGAGCCATCCGAAAGAGTTAGATCACGTTTGTACAGTGTGCTGTAAGGGATTTCCGGAAGCTCGAATATTAAAGCGTCACCTGAAAATACATCTCGATAAGAAACCCCATCAGTGCGATCAATGCGACATGTCTTTCGCCGAAAGTTCTAATCTCAGTAAACATAAAAAGAAACATACGGGAGAATTACGCAATATCAAGGGAAAACCTCATTTGTGTTCGGTATGCGGCCGCGCATTTAAATGGGCCTCCAGCTTATCGAAACACATGAAATATCATACGGGTCACAAATTGCTCACCTGTaaatattgcaataaacaGTACGTGGAGGCACGTAGTCTACGAATTCACATTCGATCCCATACAGGCGAAAGACCATACGTGTGTACCGTTTGCCAGAAGAGCTTTACTCAAATATGCAATCTCGAAAAGCATTTACGTGTTCATACAGGGGAAAAGCCGTTTTTATGTCCTACTTGCGGTAAAggATTCACGCAGTCGGGCTATGTTGGTATTCACATGCGAACGCATACCGGCGAACGGCCATACGTGTGCACAACCTGTGGAAAGGCTTTTGCAGGATCAAATACTTTGGCGATACACCAGCGAATCCATACGGGAGAAAAGCCGTAcagttgtaatttatgtgGCAAGTCGTTCAGTCGTCACGAAACGCTCGTCATACACACTAGGTCGCATACTGGCCACAAACCTCATATCTGTTCTGTATGCAATAAGGGCTTCACATCGTCGGGGCATCTTTCTGGTCACATGAGAACGCATACCGGTGAAAAGCCACACGGATGCCCCGAATGCGGAAAACGATTTGCCGGTTCCAGCAGCCTTAAAGTTCACATGCGCGCACATTCTGGAGAGAAGCCGTTTATCtgcaaaatttgcaataaGGCATTCACACAATCGAGCACTTTACAGCAGCACATAAGCACTCACGATTTagttgaaaaaattaagaaaatcgaAACCATGCAGGTTGCCGAAATAATCACCGGAGAAACGATTCATACAGTGCAAGTGCAAGCGATAGGTTCGATATAG
Protein Sequence
MDMSVYLTAPMQLDKVCRACLSEKGDMRPLFGACLDEMLVSFASIQVQENDGLPNLMCVQCVLQCSRAYTFKQQCEKSDNILRQYISQDFQEQLLKAESTENKQQIQEHLQITETVIPDDLPSELINVSYIEDGNFKIEVKDLYNIATAEPESEKKDIIVKEEKSHKQKYPCSKCDESFPLKVDLKVHMMSHPKELDHVCTVCCKGFPEARILKRHLKIHLDKKPHQCDQCDMSFAESSNLSKHKKKHTGELRNIKGKPHLCSVCGRAFKWASSLSKHMKYHTGHKLLTCKYCNKQYVEARSLRIHIRSHTGERPYVCTVCQKSFTQICNLEKHLRVHTGEKPFLCPTCGKGFTQSGYVGIHMRTHTGERPYVCTTCGKAFAGSNTLAIHQRIHTGEKPYSCNLCGKSFSRHETLVIHTRSHTGHKPHICSVCNKGFTSSGHLSGHMRTHTGEKPHGCPECGKRFAGSSSLKVHMRAHSGEKPFICKICNKAFTQSSTLQQHISTHDLVEKIKKIETMQVAEIITGETIHTVQVQAIGSI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01345867;
90% Identity
-
80% Identity
-