Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.12 2e+02 3.2 0.0 17 46 82 111 75 118 0.82

2 8 0.11 1.9e+02 3.2 0.0 26 51 120 145 112 147 0.88

3 8 0.32 5.5e+02 1.8 0.6 25 45 147 167 141 175 0.86

4 8 0.012 20 6.3 0.8 22 44 172 194 165 198 0.82

5 8 0.018 31 5.8 0.1 21 48 199 226 194 231 0.80

6 8 0.064 1.1e+02 4.0 0.0 21 48 227 254 223 258 0.82

7 8 0.0021 3.7 8.7 0.1 21 44 255 278 251 288 0.86

8 8 0.0045 7.8 7.7 0.1 22 48 312 338 304 340 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.12	2e+02	3.2	0.0	17	46	82	111	75	118	0.82
2	8	0.11	1.9e+02	3.2	0.0	26	51	120	145	112	147	0.88
3	8	0.32	5.5e+02	1.8	0.6	25	45	147	167	141	175	0.86
4	8	0.012	20	6.3	0.8	22	44	172	194	165	198	0.82
5	8	0.018	31	5.8	0.1	21	48	199	226	194	231	0.80
6	8	0.064	1.1e+02	4.0	0.0	21	48	227	254	223	258	0.82
7	8	0.0021	3.7	8.7	0.1	21	44	255	278	251	288	0.86
8	8	0.0045	7.8	7.7	0.1	22	48	312	338	304	340	0.89

Coding Sequence: ATGTCCGAAAAGGATGAAGTAGtaaatttgaatattgaaaGCAAAGTGGATACTGTAATTAAGGAAGAACCAGTGGACAGTTGCAGTCATGATACATTGGAAGTTATAAAACAAAACACAATCTACTTTTGCAATATCAAACAAGAAAGTATGGACTACGAATCCGAAAACTCTGGCAATAACGGCGAAGAAACAGAAGATATGGTAGATAGAATTCGTTCTGAAGAAATTGAAACATCAGAAAGTAATGCACTTACAGATAAAAGATTTACATGTAGAGTATGTAACATgaaatttaaatggaaaaacAATTTGGTGAGTCACTTGAAAGTCCACACTTCCATCAAAAGGGACTTTGTTTGCACCACATGTAACGCTAGTTTTAGGTGGAAGAACAATTTGGTGAGTCACATAAAAATTCACACCGACGCCAAAGCATACACCTGCGAAGTTTGCGGTTGTAAATTCAGAACGCAACGATATCTACACAGCCACAAGCAAATCCACGCTCCCGAAAAGCGCCACACATGTCCGATTTGTGCTGCCCAATACGCCTGGAAGGTGAGTTTGGACAGGCACATCAGATctcacactggcgagaaaccatttTCTTGCAAAATTTGCCACATCAGATTTGCCGGTAGAAGTAATCTACACACGCACATGACGGTCCATTCCGacgaaaaaccgtttgcttgcAAAATCTGCGACTTTAAATTTTCGCGAAAGTACAACCTAAACAGTCACATGAAGACGCATAAAAAGGAAAAACCTTTTTCGTGCGAGATTTGCCAGGCCAAATTTGCGGGGAAGAGCAGTTTAAGGAGGCACGAACAGTCGCATTCCGGGGAAAAACCATACGCTTGCAATCAATGTGACTCGAAATTTACACGAAAATACATTTTGGAGAGTCATCAGCTGACTCACACAAACGACAAACcttttagttgtaaaaagtgTAACGCTAAATTTGTGTGGAAGAGAAGTTTAAGGAGGCACATTCAAAGTGCTCATGAAGAGAACAACTAG
Protein Sequence: MSEKDEVVNLNIESKVDTVIKEEPVDSCSHDTLEVIKQNTIYFCNIKQESMDYESENSGNNGEETEDMVDRIRSEEIETSESNALTDKRFTCRVCNMKFKWKNNLVSHLKVHTSIKRDFVCTTCNASFRWKNNLVSHIKIHTDAKAYTCEVCGCKFRTQRYLHSHKQIHAPEKRHTCPICAAQYAWKVSLDRHIRSHTGEKPFSCKICHIRFAGRSNLHTHMTVHSDEKPFACKICDFKFSRKYNLNSHMKTHKKEKPFSCEICQAKFAGKSSLRRHEQSHSGEKPYACNQCDSKFTRKYILESHQLTHTNDKPFSCKKCNAKFVWKRSLRRHIQSAHEENN

Sequence clustering based on sequence similarity using MMseqs2