Basic Information

Insect: Rhagonycha lutea
Gene Symbol: topi
Assembly: GCA_958510855.1
Location: OY294036.1:38690366-38697931[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0015 0.098 14.1 2.1 2 21 130 149 129 150 0.94

2 14 3.1e-05 0.0021 19.4 0.9 1 23 175 197 175 197 0.97

3 14 0.02 1.3 10.6 2.0 3 23 205 225 204 225 0.95

4 14 0.046 3.1 9.4 0.0 2 19 244 261 243 264 0.93

5 14 0.00011 0.0072 17.7 1.0 2 23 342 363 341 363 0.97

6 14 0.69 46 5.7 0.1 1 21 369 389 369 390 0.90

7 14 0.17 11 7.7 2.7 2 21 406 425 405 429 0.83

8 14 0.051 3.4 9.3 0.1 1 23 542 565 542 565 0.97

9 14 0.014 0.94 11.0 0.1 1 23 569 591 569 591 0.97

10 14 1.2e-06 8.2e-05 23.8 2.4 1 23 597 619 597 619 0.98

11 14 0.044 2.9 9.5 0.2 1 23 625 650 625 650 0.96

12 14 0.74 49 5.6 2.5 1 23 656 678 656 678 0.85

13 14 1e-05 0.00068 20.9 0.4 3 23 686 706 684 706 0.98

14 14 5.4e-06 0.00036 21.8 0.5 1 23 712 735 712 735 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0015	0.098	14.1	2.1	2	21	130	149	129	150	0.94
2	14	3.1e-05	0.0021	19.4	0.9	1	23	175	197	175	197	0.97
3	14	0.02	1.3	10.6	2.0	3	23	205	225	204	225	0.95
4	14	0.046	3.1	9.4	0.0	2	19	244	261	243	264	0.93
5	14	0.00011	0.0072	17.7	1.0	2	23	342	363	341	363	0.97
6	14	0.69	46	5.7	0.1	1	21	369	389	369	390	0.90
7	14	0.17	11	7.7	2.7	2	21	406	425	405	429	0.83
8	14	0.051	3.4	9.3	0.1	1	23	542	565	542	565	0.97
9	14	0.014	0.94	11.0	0.1	1	23	569	591	569	591	0.97
10	14	1.2e-06	8.2e-05	23.8	2.4	1	23	597	619	597	619	0.98
11	14	0.044	2.9	9.5	0.2	1	23	625	650	625	650	0.96
12	14	0.74	49	5.6	2.5	1	23	656	678	656	678	0.85
13	14	1e-05	0.00068	20.9	0.4	3	23	686	706	684	706	0.98
14	14	5.4e-06	0.00036	21.8	0.5	1	23	712	735	712	735	0.98

Sequence Information

Coding Sequence: ATGAATAATCCTAATATTTTTCTCACGGTAACCCGTATATCCGACGATGGCACAGTTAGCTCCTTTCAAATCGAGGAGGATTTTATTACTCATGAAATGGTGTCGACAACTCCAATTTCGAGCGAAAATGTGAACTTCAACTCGCAGCGCCGTTGGAGTCACGCAGAAGATACTAAAGTAAATTTAAGTTATCGTTATTTGGAGCCTGACGAGCAATCTATTACTATAGTCAAGATTGGAGGTGTCGAAGATTTAAATCCGTTAAATTATGCTACCGAAATCAGTACCGTATTAAGTGATCCTGGAGATTgcaaacaatataatattaatagttcTCTGGTCCAAGTTAGGCGCGAAAGTAAAATACCAAATATACCAACAATGGTTAGGTGTCAAAATTGTGACACCAATTTTCCCACCAAATATCAGTATCAGCGTCACCAATGCGAATTTAATGCAGACAAAGTGGTGCTGAAAGCAGATGCAGATATCAAGGATTTTGAAAAGGGCATGAGAATCAAGTACGACTGTGTAACTTGTGGTAAGCAGTTTgtgagtaaaaataatttagaccGGCATCAATCGAGTCACGACAACACGCAAGAAAATATTTGCGAGCACTGCAACAAAcaatttgtaagtgaaaatcgACTTCGGATTCATAAAGAAAATCATTGTAAAAAAGCTGGCGACATTTCTAAATTCTACCGCAGCGATGTTACTGTTTGGAAATGTGTTAAATGCAATCAAGTATTTGCCACACCTGCTTCGGCTAACAAACATGCAGAATTGTGTGTCGAAGTTCAAAGTGAGAACATGCTTCTGAATATAAAATCAGAGTCTTTGAATGTGTCAGAAGAGAGCAGTGGACTTCAACTGCTGAGTGAAGAAATTAAAAGCTTATCTTATATTTCTCCAGAAATTATAACCGAagagaacattttaattgataattcgAACAActgtaataaaattgataatagtACTCCAAATGTAGAGAAAGTACTAACTGAGTTATTGCTTCAATGCGAATACTGCAATAGAACTTATTCGGAAAGAAATTTACTTTTAGCCCATCAAAAGAAGCACAGCACAAAAGTAAATTACGAATGCGTAACATGCAGAGAAACATTTGATTCGTATACAACTGCTGCGAAGCATTGGATAACCAAGTGTTCCGATGAAGCTAATTTGTTTTATCTTCCTAAAATGACATATTGTGAGTACTGCGATAGAACTTTTAAATCTCACGAAATATTGTATACCCACAAAATAAAGAAGAAGCATTACACTCCCAAATTACATGTTGTAGATAACGATAATGTAAATAACTTAAATGCGGTTGGAAATAAAGATGTATTTCTGGTCAAGCTTATTGAAGATGTCCTTACAACTATTAATAAAGATAAAGAACTTACGCAGGAAAAACATAACAACGATAAGGAAAATTTAACTGAAGAATACGGTCAAAACTTACTATCCATAAAAGATGAATTAACTCCGAAGAACTTAAACCAAGAGAATGCCGAACCGGAAAAGAAGAAGCGAGGCCGCAAACGCAAGTGGCCAAAACAAGCTACGAAAACTAAACGTCTAGCTTTTGTCGTTGAAGAGGGTTATAAGTATCAATGTGAGCGTTGTGTTATGATTTTTGACAATGTTACCGATTTGGAACTCCATCGTGAAAAGGAACATGCTTCTAATTTTTCATGCGAGGAATGTggacaggtTGTTCACAGTGCAAAAGCATTGGTCATTCACAGTAGAGCCCACCAGAGTCTGAAACCATATGTTTGTGAGCAGTGTGGCAGAAGTTATTCTCAAACTTCTCATTTATGGCAACATATGAGATTCCACCAAGgcaTTAAACCTTTTGCATGCCCCCATGAAGGATGCGAAGCACGTTACACTATTAGACCTGATTTAAAAGATCACATTCGCAAAGTGCACACTCGCGAAAGGCCATTCAAGTGTGCCGTGTGCAACAAATGCTTCCTAACTGGATCTGTTTACTATCAACATAGACTCATACACACCAATGATCGAAGATACGGCTGTGATaTTTGCGACAAGAGATTTTTCCGAGCCGATGCTTTAAACAATCACCGAAGAATTCATACAGATGAAAGACCATAcccatgtgaaatttgtggaaGAGAGTTTCGTCAAAAAGGAGATCGAAATAAGCATGTACGGACACAACATCcagattaa
Protein Sequence: MNNPNIFLTVTRISDDGTVSSFQIEEDFITHEMVSTTPISSENVNFNSQRRWSHAEDTKVNLSYRYLEPDEQSITIVKIGGVEDLNPLNYATEISTVLSDPGDCKQYNINSSLVQVRRESKIPNIPTMVRCQNCDTNFPTKYQYQRHQCEFNADKVVLKADADIKDFEKGMRIKYDCVTCGKQFVSKNNLDRHQSSHDNTQENICEHCNKQFVSENRLRIHKENHCKKAGDISKFYRSDVTVWKCVKCNQVFATPASANKHAELCVEVQSENMLLNIKSESLNVSEESSGLQLLSEEIKSLSYISPEIITEENILIDNSNNCNKIDNSTPNVEKVLTELLLQCEYCNRTYSERNLLLAHQKKHSTKVNYECVTCRETFDSYTTAAKHWITKCSDEANLFYLPKMTYCEYCDRTFKSHEILYTHKIKKKHYTPKLHVVDNDNVNNLNAVGNKDVFLVKLIEDVLTTINKDKELTQEKHNNDKENLTEEYGQNLLSIKDELTPKNLNQENAEPEKKKRGRKRKWPKQATKTKRLAFVVEEGYKYQCERCVMIFDNVTDLELHREKEHASNFSCEECGQVVHSAKALVIHSRAHQSLKPYVCEQCGRSYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFKCAVCNKCFLTGSVYYQHRLIHTNDRRYGCDICDKRFFRADALNNHRRIHTDERPYPCEICGREFRQKGDRNKHVRTQHPD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01292376;
90% Identity: iTF_00271674;
80% Identity: -