Basic Information

Insect: Rhagonycha fulva
Gene Symbol: topi
Assembly: GCA_905340355.1
Location: HG996555.1:71184431-71193417[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0031 0.089 14.1 2.1 2 21 130 149 129 150 0.94

2 14 6.6e-05 0.0019 19.4 0.9 1 23 175 197 175 197 0.97

3 14 0.042 1.2 10.6 2.0 3 23 205 225 204 225 0.95

4 14 0.097 2.8 9.4 0.1 2 19 244 261 243 264 0.93

5 14 0.00023 0.0065 17.7 1.0 2 23 341 362 340 362 0.97

6 14 1.4 42 5.7 0.1 1 21 368 388 368 389 0.90

7 14 0.35 10 7.7 2.7 2 21 405 424 404 428 0.83

8 14 0.14 4.1 8.9 0.1 1 23 541 564 541 564 0.97

9 14 0.029 0.85 11.0 0.1 1 23 568 590 568 590 0.97

10 14 2.6e-06 7.5e-05 23.8 2.4 1 23 596 618 596 618 0.98

11 14 0.092 2.7 9.5 0.2 1 23 624 649 624 649 0.96

12 14 1.5 45 5.6 2.5 1 23 655 677 655 677 0.85

13 14 2.1e-05 0.00062 20.9 0.4 3 23 685 705 683 705 0.98

14 14 1.1e-05 0.00033 21.8 0.5 1 23 711 734 711 734 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0031	0.089	14.1	2.1	2	21	130	149	129	150	0.94
2	14	6.6e-05	0.0019	19.4	0.9	1	23	175	197	175	197	0.97
3	14	0.042	1.2	10.6	2.0	3	23	205	225	204	225	0.95
4	14	0.097	2.8	9.4	0.1	2	19	244	261	243	264	0.93
5	14	0.00023	0.0065	17.7	1.0	2	23	341	362	340	362	0.97
6	14	1.4	42	5.7	0.1	1	21	368	388	368	389	0.90
7	14	0.35	10	7.7	2.7	2	21	405	424	404	428	0.83
8	14	0.14	4.1	8.9	0.1	1	23	541	564	541	564	0.97
9	14	0.029	0.85	11.0	0.1	1	23	568	590	568	590	0.97
10	14	2.6e-06	7.5e-05	23.8	2.4	1	23	596	618	596	618	0.98
11	14	0.092	2.7	9.5	0.2	1	23	624	649	624	649	0.96
12	14	1.5	45	5.6	2.5	1	23	655	677	655	677	0.85
13	14	2.1e-05	0.00062	20.9	0.4	3	23	685	705	683	705	0.98
14	14	1.1e-05	0.00033	21.8	0.5	1	23	711	734	711	734	0.98

Sequence Information

Coding Sequence: ATGAATAATCCTAATATTTTTCTCACGGTAACCCGTATATCCGACGATGGTACAGTTAGCTCCTTTCAAATCGAAGAAGATTTTATTACCCACGAAATGGTGTCCGCAACTCCAATTTCGAGCGAAAATGTGAACTTCAACTCGCAACGCCGTTGGAGTCACGCAGAAGATACTAAAGTTAATTTAAGTTATCGTTATTTGGAGCCCGACGAGCAATCTATTACTATAGTCAAGATTGGAGGTGTCGAAGATTTAAATCCCTTAAATTATGCTACCGAAATCAGTACCGTATTAAGTGATCCTGGAGATTGTAAGCAATATAATATTAATAGTTCTCTGGTCCAAGTTAGACGCGAAAGTAAAATACCAAATATACCAACAATGGTTAGATGTCAAAATTGTGACACCAATTTTCCCACCAAATATCAGTACCAGCGTCACCAATGCGAATTTAATGCAGACAAAGTGGTCCTGAAAGCAGATGCAGATATCAAGGATTTTGAAAAGGGTATGAGAATCAAGTACGACTGTGTAACTTGTGGTAAGCAGTTTGTGAGTAAAAATAATTTAGACCGGCATCAATCGAGTCACGACAACACGCAAGAAAATATTTGCGAGCACTGCAACAAACAATTTGTAAGTGAAAATCGACTTCGGATTCACAAAGAAAATCATTGCAAAAAAGCTGGCGACATTTCTAAATTCTACCGCAGCGATGTTACTGTTTGGAAATGTGTTAAATGCAATCAAGTATTTGCCACACCTACTTCGGCTAACAAACATGCAGAATTGTGTGTCGAAGTTCAAAGTGAAAATATGCTTATGAATATAAAATCCGAGTCTTTAAATGTATCAGAAGAAAGCAGTGGACTTCAACTTTTGAGTGAAGAAATTAAAAATTTATCTTTTATTTCTTCAGAAATTATAACCGAAGAGAGCATTTCAATTGATAATTCAAACTGTAATAAACTTGATAATAGTACTCCAAATGTAGAGAAAGTACTAACTGAGTTGTTACTACAATGCGAATACTGTAATAGAACTTATTCGGAAAGAAATTTACTTTTAGCCCATCAAAAAAAGCACAATACAAAAGTAAATTATGAATGCGTTACATGCAGAGAAACTTTTGATTCGTATACAACTGCTGCGAAGCATTGGATAACCAAGTGTTCTGATGAAGCTAATTTGTTTTATCTTCCTAAAATGACATATTGTGAGTACTGTGATAGAACTTTTAAATCTCACGAAATATTGTATACCCACAAAATAAAGAAGAAGCATTACACTCCTAAATTACATGTTGTGGATAACGATAATGTAAATAACTTAAATGCCGTTGGAAATAAAGATGTGTTTCTGGTCAAGCTTATTGAAGATGTTCTTACAACTATTAATAAAGATAAAGAACTTACCCAAGAAAAACATAACAACGATAAGGAAAATTTAACTGAAGAATACGGTCAAAACTTATTATCCATAAAAGATGAATTAACTCCGAAGAATTTAAACCAAGAGAATGCCGAACCGGAAAAGAAGAAGAGAGGCCGCAAACGCAAGTGGCCTAAACAAGCCACGAAAACTAAACGTCTAGCTTTTGTCGTCGAAGAGGGTTATAAGTATCAATGTGAGCGATGTGTTTTGATTTTTGACAATGTTACCGATTTGGAACTTCATCGTGAAAAAGAACATGCTTCTAATTTTTCATGCGAGGAATGTGGACAGGTTGTTCACAGTGCAAAAGCATTGGTCATTCACAGTAGAGCCCATCAGAGTCTGAAACCGTATGTTTGTGAGCAATGTGGCAGAAGTTATTCTCAAACTTCTCATTTATGGCAACATATGAGATTCCACCAAGGCATTAAACCTTTTGCATGCCCCCACGAAGGATGCGAAGCACGTTACACTATTAGACCTGATTTAAAAGATCACATTCGTAAAGTGCACACTCGCGAAAGGCCATTCAAGTGTGCCGTGTGCAACAAATGCTTCCTAACTGGATCTGTTTACTACCAACATCGCCTCATACACACCAATGATCGAAGATACGGCTGTGATATTTGCGACAAGAGATTTTTCCGAGCCGATGCTTTAAACAATCACCGAAGAATTCATACAGATGAAAGACCATATCCTTGTGAAATTTGTGGAAGAGAGTTTCGTCAAAAAGGAGATCGAAATAAGCATGTGCGGACACAACATCCGGATTAA
Protein Sequence: MNNPNIFLTVTRISDDGTVSSFQIEEDFITHEMVSATPISSENVNFNSQRRWSHAEDTKVNLSYRYLEPDEQSITIVKIGGVEDLNPLNYATEISTVLSDPGDCKQYNINSSLVQVRRESKIPNIPTMVRCQNCDTNFPTKYQYQRHQCEFNADKVVLKADADIKDFEKGMRIKYDCVTCGKQFVSKNNLDRHQSSHDNTQENICEHCNKQFVSENRLRIHKENHCKKAGDISKFYRSDVTVWKCVKCNQVFATPTSANKHAELCVEVQSENMLMNIKSESLNVSEESSGLQLLSEEIKNLSFISSEIITEESISIDNSNCNKLDNSTPNVEKVLTELLLQCEYCNRTYSERNLLLAHQKKHNTKVNYECVTCRETFDSYTTAAKHWITKCSDEANLFYLPKMTYCEYCDRTFKSHEILYTHKIKKKHYTPKLHVVDNDNVNNLNAVGNKDVFLVKLIEDVLTTINKDKELTQEKHNNDKENLTEEYGQNLLSIKDELTPKNLNQENAEPEKKKRGRKRKWPKQATKTKRLAFVVEEGYKYQCERCVLIFDNVTDLELHREKEHASNFSCEECGQVVHSAKALVIHSRAHQSLKPYVCEQCGRSYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFKCAVCNKCFLTGSVYYQHRLIHTNDRRYGCDICDKRFFRADALNNHRRIHTDERPYPCEICGREFRQKGDRNKHVRTQHPD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00268945; iTF_00271674; iTF_01294172; iTF_00270260; iTF_00927991; iTF_00273020;
90% Identity: iTF_00271674;
80% Identity: -