Basic Information

Insect: Rhagonycha lutea
Gene Symbol: Hr39
Assembly: GCA_958510855.1
Location: OY294037.1:1097059-1107492[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.89 1.1e+04 -3.6 0.1 79 123 33 74 8 91 0.48

2 5 2 2.4e+04 -4.7 7.0 48 153 137 236 107 287 0.40

3 5 6.1e-08 0.00073 20.0 0.0 1 21 391 411 391 416 0.91

4 5 0.00011 1.3 9.3 0.8 55 158 419 516 411 531 0.60

5 5 1.3e-73 1.5e-69 236.4 0.1 202 408 523 724 514 724 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.89	1.1e+04	-3.6	0.1	79	123	33	74	8	91	0.48
2	5	2	2.4e+04	-4.7	7.0	48	153	137	236	107	287	0.40
3	5	6.1e-08	0.00073	20.0	0.0	1	21	391	411	391	416	0.91
4	5	0.00011	1.3	9.3	0.8	55	158	419	516	411	531	0.60
5	5	1.3e-73	1.5e-69	236.4	0.1	202	408	523	724	514	724	0.97

Sequence Information

Coding Sequence: ATGGCCACAAACATGAGATCACCAAACGTGTCTATCACCACAATCAACGTGGACCCCTATCCGCCGACTTCTCTATCCAACGGCAGCATCCCAAAAACCACCCCCGTGTCCACGGATTCCCAATACGCATCTTCGCCTTCCACCTTAAACGATGGAGATATTTTGGATAACAGTTTGGACGCAGAGGTGGCCCAGATCGACTTTCACGCAGCTTCCGTTAATTTGCGTAACAAGAAGAAATGGGAAGAGAACGAGGCAGCTAGACCCATGTCTTGGGAAGGTGAACTCTCGGATGGGGAAAGAGACATGTGTATAGATGTAGACGAAAGATCTCAGCACACCGAAAAGCTTTCTTATGTTCATTCGAAACAAAATCTTCCTTTATCCGAATTAAAGGAAAGTCCCATACTGAGGATAAAGCAGCAACCTGCGGTGAATAATTATTCCCTTCACAGTACACCAAACAATTCGCCTTTGTTAAGCCAACGTCACGCTGCCGCGCCGGTTCTCAGTCACAAAGAAATTCTCCACAAAACCTTAAACATCCCGGCAACTCCGAGTCCCGATTCGGCCATACATTCTGGTTACAGTGTGTTCAGTTCTCCAAGTCAGAGTCCCCTTACTCAAAGACACTTAACTCCTAGTTTAAGTCGTAACAATAGTGATGCTTCACATTCGAGTTGTTGTAGTTATTCCAGTGTATCCGTGTCCGTTTCTCCGACTCAACAATTTTCGCCCACTCACAGTCCTATACAGGGTCGTCATCATATGCTAGGTGGAATCCACAATAGTCCGTTACATCACAACATTTTATATCGTAGCTTACAAGACGaaacatcaaatttacaatatccCAACGAACAGGAAGGTTCTTTAGAGGAGGTAGAAGATAAGACTGGTTTAATTCACACATCTCTTCCCGCCCAACCCGGCATCTCGCGACAACAACTGATAAATAgCCCGTGTCCAATATGTGGTGATAAAATATCGGGATTTCATTATGGAATCTTTAGTTGCGAATCCTGCAAGGGCTTTTTTAAACGCACAgtgcaaaatagaaaaaattacgTTTGTCTAAGGGGCGCCGCCTGTCCGGTTACGGTAGCCACGAGAAAAAAGTGTCCAGCTTGTAGATTCGAAAAATGTTTACAATGTGGAATGAAGCTTGAAGCCATACGAGAAGACCGAACGAGGGGTGGTCGATCCACCTATCAATGTTCGTATTCCCTTCCGCCATCGTTAACTGGACATTCTGAATTGAGGACGAGTTCTTCCGATCTTCGACAAAATTACGGCGATTCGCCACAAGTTTTGAGAGTGAAAGTCGAACCAGCGGAATCGAATTCGTATACGAAGCGGTCTTCGCACAGTTCCAGATTAGGGGTCCCGCCGTTATTGcagGAAATAATGGACGTGGAGCACCTATGGCATTACAACGAGATGAGCACTTTCAAAGAGGGTGCTTCTAGTTTGGACAAAGCAAGTTCTAGCAGCTCTTCCTCCTCCTCCTCGTCGGTACCAAACTTATCGCAACATCCGTTACTAGGTAGTACGGCGTTGGCAAATTCGTCAGAAAACAATCCAGATTTTGTGGCCAATTTGTGCAACATAGCCGACCATCGtttatataaaattgttaagtggtgtaaaagtttaccattgtttaaaaatatttctATCGAcgatcaaatttgtttgttaataAATTCTTGGTGCGAATTGTTATTGTTCTCGTGTTGTTTTCGATCGGTGTCGAGTCCCGGAGAAATTAGAGTGTCGTTAGGAAAAAGTATCAATTTGGAACAAGCAAAGGAGATGGGATTGGGGGTTTGTATCGAGCGGATGTTAAATTTTACCGACCATCTTAGAAGGTTGAGGGTGGATCAGTACGAATATGTTGCCATGAAAGTTATCGTTTTACTTACGTCGGatACCTCCGAGTTGAGAGAACCCGAGAAAGTTAGGGCGTCGCAAGAGAAAGCGTTGCAAGCCTTGCAGCATTACACCCTGGCTCACTATCCAGATGCGCCTGCAAAGTTTGGAGAACTGTTACTTAGGATTCCTGAATTACAACGAACGTGTCAGGTCGGGAAGGAGATGTTGACGATAAAATCGAAAGACGGCGAAGGGCCAAGTTTTAACCTGCTCCTGGAGCTACTTCGAGGGGACCATTAG
Protein Sequence: MATNMRSPNVSITTINVDPYPPTSLSNGSIPKTTPVSTDSQYASSPSTLNDGDILDNSLDAEVAQIDFHAASVNLRNKKKWEENEAARPMSWEGELSDGERDMCIDVDERSQHTEKLSYVHSKQNLPLSELKESPILRIKQQPAVNNYSLHSTPNNSPLLSQRHAAAPVLSHKEILHKTLNIPATPSPDSAIHSGYSVFSSPSQSPLTQRHLTPSLSRNNSDASHSSCCSYSSVSVSVSPTQQFSPTHSPIQGRHHMLGGIHNSPLHHNILYRSLQDETSNLQYPNEQEGSLEEVEDKTGLIHTSLPAQPGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAACPVTVATRKKCPACRFEKCLQCGMKLEAIREDRTRGGRSTYQCSYSLPPSLTGHSELRTSSSDLRQNYGDSPQVLRVKVEPAESNSYTKRSSHSSRLGVPPLLQEIMDVEHLWHYNEMSTFKEGASSLDKASSSSSSSSSSSVPNLSQHPLLGSTALANSSENNPDFVANLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSVSSPGEIRVSLGKSINLEQAKEMGLGVCIERMLNFTDHLRRLRVDQYEYVAMKVIVLLTSDTSELREPEKVRASQEKALQALQHYTLAHYPDAPAKFGELLLRIPELQRTCQVGKEMLTIKSKDGEGPSFNLLLELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00951009;
90% Identity: iTF_00271366;
80% Identity: iTF_01293877;