Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.012 5.3 8.1 0.2 21 52 54 85 47 86 0.78

2 9 0.036 16 6.6 0.1 21 51 82 112 80 113 0.85

3 9 0.34 1.5e+02 3.4 0.2 21 44 110 133 108 137 0.76

4 9 0.012 5.4 8.1 0.1 21 46 138 163 130 169 0.79

5 9 0.055 25 5.9 0.0 21 46 166 191 162 197 0.84

6 9 0.67 3e+02 2.5 0.0 21 44 194 217 190 221 0.75

7 9 0.0092 4.1 8.4 0.1 21 48 222 249 214 255 0.78

8 9 3.1 1.4e+03 0.3 0.1 21 31 250 260 246 276 0.82

9 9 0.084 38 5.4 0.2 21 48 278 305 270 307 0.82

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.012	5.3	8.1	0.2	21	52	54	85	47	86	0.78
2	9	0.036	16	6.6	0.1	21	51	82	112	80	113	0.85
3	9	0.34	1.5e+02	3.4	0.2	21	44	110	133	108	137	0.76
4	9	0.012	5.4	8.1	0.1	21	46	138	163	130	169	0.79
5	9	0.055	25	5.9	0.0	21	46	166	191	162	197	0.84
6	9	0.67	3e+02	2.5	0.0	21	44	194	217	190	221	0.75
7	9	0.0092	4.1	8.4	0.1	21	48	222	249	214	255	0.78
8	9	3.1	1.4e+03	0.3	0.1	21	31	250	260	246	276	0.82
9	9	0.084	38	5.4	0.2	21	48	278	305	270	307	0.82

Coding Sequence: ATGGATACTTCATGTAAACGTGAAGTGGATGATAAATCGGAGGAAACGGATGACATAAAATTTAACTTAGAAGATCTTCATCATTCGATAGATATTAAAGATGAAGAGAGCTATGGAGAAGCATTAATAAATGCAAAATCTGCAACATATACAAGTATTCGAGAGAAATGTTTTTCTTGTGATGTTTGTGGTTATAAATGTACTCGAAAATCAAATTTAAAAAGACATTTAAAAATTCACACGGGGGAGAAACCGTTTTCTTGTTCGATTTGTGACTATAATTGTGCTCAAAAATCTTCTTTAAAAATACATTTACAAATGCACACGGGGGAGAAACCGTTTTCTTGTAAGATTTGTGACTATAAATGTGTACGCAGTCCAGATTTAAAAAATCATGTAAGAACCCACACAGGCGAGAAACCTTTTGTTTGTAAGATTTGTGACTATAAGTGTGCTCGTAAAAAATCTTTAAAAAGACATTTAACAACTCACACAGGGGAGAAACCTTTTGCTTGTGAGATTTGTGACTATAAAAGTGCTCAAAAATCATCCTTAAAAAAACATTTAACAACTCACACGGGGGAGAAACCATTTGCTTGTGAGATTTGTAACTATAAAGGTGCTCGTAAATCATTTTTAAAAGAACATTTAAAAACTCACACGGGGGAGAAACCATTTGCTTGTGAGATTTGTAACTATAAATGTGCTCGTAAATCAAATTTAAAAGAACATTTAAAAACTCACACGGGGGAGAAACCATTTGCTTGTGAGATTTGTAACTATAAAGGTGCTAGTAAATCACTTTTAAAAGAACATGTAAAAACTCACACGGGGGAGAAACCGTTTTCTTGTGAGATTTGTGACTATAAATGTGCACGAAAAAGCTCTTTAAAAAATCATTTAAAAACTCCACACAGGCGAGAAACCTTTTTCATGTAA
Protein Sequence: MDTSCKREVDDKSEETDDIKFNLEDLHHSIDIKDEESYGEALINAKSATYTSIREKCFSCDVCGYKCTRKSNLKRHLKIHTGEKPFSCSICDYNCAQKSSLKIHLQMHTGEKPFSCKICDYKCVRSPDLKNHVRTHTGEKPFVCKICDYKCARKKSLKRHLTTHTGEKPFACEICDYKSAQKSSLKKHLTTHTGEKPFACEICNYKGARKSFLKEHLKTHTGEKPFACEICNYKCARKSNLKEHLKTHTGEKPFACEICNYKGASKSLLKEHVKTHTGEKPFSCEICDYKCARKSSLKNHLKTPHRRETFFM

Sequence clustering based on sequence similarity using MMseqs2