Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.73 3.3e+02 2.3 0.0 23 46 92 115 86 123 0.84

2 8 0.41 1.9e+02 3.1 0.0 26 51 124 149 118 151 0.88

3 8 1.1 5.1e+02 1.7 0.3 25 45 151 171 146 174 0.86

4 8 0.0065 2.9 8.9 0.5 20 44 174 198 168 202 0.83

5 8 0.066 30 5.7 0.1 21 47 203 229 197 234 0.80

6 8 0.058 26 5.9 0.0 21 51 231 261 227 262 0.84

7 8 0.041 19 6.3 0.1 21 44 259 282 255 292 0.86

8 8 0.018 8 7.5 0.0 22 48 316 342 310 345 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.73	3.3e+02	2.3	0.0	23	46	92	115	86	123	0.84
2	8	0.41	1.9e+02	3.1	0.0	26	51	124	149	118	151	0.88
3	8	1.1	5.1e+02	1.7	0.3	25	45	151	171	146	174	0.86
4	8	0.0065	2.9	8.9	0.5	20	44	174	198	168	202	0.83
5	8	0.066	30	5.7	0.1	21	47	203	229	197	234	0.80
6	8	0.058	26	5.9	0.0	21	51	231	261	227	262	0.84
7	8	0.041	19	6.3	0.1	21	44	259	282	255	292	0.86
8	8	0.018	8	7.5	0.0	22	48	316	342	310	345	0.89

Coding Sequence: ATGTCCGAAAAGGATGAAATAGTAAATTTGAATATTGACAACAACCTGAATACTGTAATCAAGGAAGAACCAGTGGACAGTTGCAGTTATGAAAATTGCGAACAAGTTCACGATACATTGGAAGCTATAAAACGAAACACAATCTACATTTGCAATATCAAACAAGAAAGTATGGACTATGAATCCGAAAACTCGGGCAATAATGGTGAAGAAACGAAAGATAATATTTGTTCTGAAAATCGTTCGGATGAAATCGACATGTCGGAAATCGATAAAAGATTTACATGTAGAGTATGCAACATGAAATTTAAATGGAAAAATAACTTGGTGAGTCACTTGAAAGTCCACACTTCCATCAAAAGGGACTTTGTTTGCACCACATGTAACGCTAGTTTTAGGTGGAAAAACAATTTGGTGAGTCACATAAAAATTCATACCGATGCGAAAGCATACACTTGCGAAGTGTGCGGTTGTAAATTCAGAACGCAACGGTACCTACACAGCCATAAGCAAATTCACGCTTCCGAAAAACGGCACACGTGTCCGATTTGTGCAGCCCAATACGCCTGGAAGGTGAGTTTGGACAGGCATATAAGATCTCACACTGGCGAGAAACCATTTTCTTGTAAAATTTGCCACATCAGATTTGCCGGTAGAAGTAATCTACACACGCACATGACGGTCCATTCCGACGAAAAGCCGTTCGCTTGCAAAATCTGCAACTTTAAATTTTCTCGAAAGTACAACTTAAACAGTCACTTGAAGACACACAAAAAGGAGAAACCTTATTCGTGCGAGATTTGTCAAACAAAGTTTGCAGGGAAGAGTAGTTTAAGGAGGCACGAACAGTCTCATTCCGGGGAAAAACCGTACGCATGCAATCAATGCGACTCGAAATTTACACGTAAATACATTTTGGATAGTCATAAGTTGACTCACACGAACGACAAACCTTTCGGTTGCGAAAAGTGTAACGCTAAATTTGTGTGGAAGAGAAGTTTAAGAAGGCACATTCAAAGTGCTCATGTAGAGAATAACTAG
Protein Sequence: MSEKDEIVNLNIDNNLNTVIKEEPVDSCSYENCEQVHDTLEAIKRNTIYICNIKQESMDYESENSGNNGEETKDNICSENRSDEIDMSEIDKRFTCRVCNMKFKWKNNLVSHLKVHTSIKRDFVCTTCNASFRWKNNLVSHIKIHTDAKAYTCEVCGCKFRTQRYLHSHKQIHASEKRHTCPICAAQYAWKVSLDRHIRSHTGEKPFSCKICHIRFAGRSNLHTHMTVHSDEKPFACKICNFKFSRKYNLNSHLKTHKKEKPYSCEICQTKFAGKSSLRRHEQSHSGEKPYACNQCDSKFTRKYILDSHKLTHTNDKPFGCEKCNAKFVWKRSLRRHIQSAHVENN

Sequence clustering based on sequence similarity using MMseqs2