Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 1.2 5.3e+02 1.7 0.1 26 52 96 122 82 123 0.73

2 9 1.4 6.3e+02 1.5 0.0 21 47 119 145 117 152 0.79

3 9 2.2 9.8e+02 0.8 0.0 21 46 147 172 142 174 0.75

4 9 0.017 7.9 7.5 0.0 21 52 175 206 173 208 0.82

5 9 1.4 6.5e+02 1.4 0.1 21 44 203 226 199 231 0.75

6 9 0.095 43 5.2 0.1 21 48 231 258 227 262 0.77

7 9 0.0095 4.3 8.4 0.0 21 51 259 289 256 290 0.87

8 9 0.0055 2.5 9.1 0.0 21 44 287 310 285 315 0.90

9 9 0.37 1.7e+02 3.3 0.0 21 46 315 340 312 342 0.83

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	1.2	5.3e+02	1.7	0.1	26	52	96	122	82	123	0.73
2	9	1.4	6.3e+02	1.5	0.0	21	47	119	145	117	152	0.79
3	9	2.2	9.8e+02	0.8	0.0	21	46	147	172	142	174	0.75
4	9	0.017	7.9	7.5	0.0	21	52	175	206	173	208	0.82
5	9	1.4	6.5e+02	1.4	0.1	21	44	203	226	199	231	0.75
6	9	0.095	43	5.2	0.1	21	48	231	258	227	262	0.77
7	9	0.0095	4.3	8.4	0.0	21	51	259	289	256	290	0.87
8	9	0.0055	2.5	9.1	0.0	21	44	287	310	285	315	0.90
9	9	0.37	1.7e+02	3.3	0.0	21	46	315	340	312	342	0.83

Coding Sequence: ATGGATGACGAAAGTTTAACTCCGATCGATTTAGAAATGCGATCGGATGAAAAGGAGAGATGTCTCGAAGACCAAAATCCAATTTCAATACAGTCGCTCGAACAAGGAACGAATGCCAGAGAAACTCCGTGCTATTCAAATAGCTACTACCCTCAAATCAAGATGGAAGAAATGGAATTCAAATTGGAAGATTTGCATCATTCTATCGACATCAAAGATGAACCTTCAATTTTAGAATTTCAACCAAATAGAAAATCAAAACCAAAAACGGGCAGGGAACGGTTCGCATGTGAAATTTGTAATTATAAAAGTGCACGGAAAGAAACTTTAATGAGGCATTTAAAAATCCATACTGGGGAAAAACCGTTTGCGTGTGAAGTATGCGAGTACAAATGTGCCAAAAAGGAATATTTAAAAAATCATTTAAAAACTCATACTGGAGAGAAACCGTTTGCTTGTGAGATGTGTGACTATAAATGTACTATAAAATCATCTTTAAAACAACATTTAAAAATCCACACGGGGGAAAAACCATTTGCTTGTGAGATATGTGACTATAAAGGTATTACAAAATCATCTTTAAAACGACATTTAAGAATTCACACGGGGGAAAAACCATTTGCTTGTATGATTTGTGGTTATAAAAGTCCACGCAGATCATATCTAAAAGAACATTTAAAAACTCACACAGGGGAAAAGCCGTTTGCTTGTAAGATTTGCGACTACAAATGTGCGCGTAACTCGCATTTAAAGGTACATTTAAAAATCCACACAGAGGAAAAACCGTTCATTTGTAAGATTTGTGACTCTAAATTTAAACAAAAATCAGCTTTAAAATGGCATTTAAAAATTCACACTGGCGAAAAGCCCTTTGTTTGTGAGATTTGTGACTTCAAAACTGTACAAAAAGAATCTTTAAGAAGACATTTATTAACTCACACAGGGGAGAAACCGTTTACTTGTTGGGTTTGTGGCTTTAAAAGTGCATATAAGTCAAGTTTAAGATCTCATTTAAAAATTCACGCCTAA
Protein Sequence: MDDESLTPIDLEMRSDEKERCLEDQNPISIQSLEQGTNARETPCYSNSYYPQIKMEEMEFKLEDLHHSIDIKDEPSILEFQPNRKSKPKTGRERFACEICNYKSARKETLMRHLKIHTGEKPFACEVCEYKCAKKEYLKNHLKTHTGEKPFACEMCDYKCTIKSSLKQHLKIHTGEKPFACEICDYKGITKSSLKRHLRIHTGEKPFACMICGYKSPRRSYLKEHLKTHTGEKPFACKICDYKCARNSHLKVHLKIHTEEKPFICKICDSKFKQKSALKWHLKIHTGEKPFVCEICDFKTVQKESLRRHLLTHTGEKPFTCWVCGFKSAYKSSLRSHLKIHA

Sequence clustering based on sequence similarity using MMseqs2