Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.021 9.6 7.3 0.0 20 49 83 112 76 115 0.77

2 7 0.0018 0.79 10.7 0.0 21 45 112 136 108 143 0.90

3 7 6.1 2.8e+03 -0.6 0.1 24 45 143 164 139 171 0.66

4 7 0.011 5.2 8.1 0.2 21 51 168 198 164 199 0.81

5 7 0.0044 2 9.5 0.0 22 51 197 226 194 227 0.87

6 7 0.0087 3.9 8.5 0.2 21 47 224 250 221 255 0.80

7 7 0.33 1.5e+02 3.4 0.1 21 46 252 277 248 281 0.75

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.021	9.6	7.3	0.0	20	49	83	112	76	115	0.77
2	7	0.0018	0.79	10.7	0.0	21	45	112	136	108	143	0.90
3	7	6.1	2.8e+03	-0.6	0.1	24	45	143	164	139	171	0.66
4	7	0.011	5.2	8.1	0.2	21	51	168	198	164	199	0.81
5	7	0.0044	2	9.5	0.0	22	51	197	226	194	227	0.87
6	7	0.0087	3.9	8.5	0.2	21	47	224	250	221	255	0.80
7	7	0.33	1.5e+02	3.4	0.1	21	46	252	277	248	281	0.75

Coding Sequence: ATGGAAAACTTTAACAATATTTTGGATAGCTGTAAAGTGGAAGTTAAAGCGGAGGAATTTGAAGATTTTAATTTAGAAGAACTACATCATTCAATAGATATCAAGGAAGAAGACGAAGATAGGACAGCTTTAATAAAAGAGAAACCTGCAAAAAATAATGGTATTCGGGGGAAATTCTTTTATTGTGAGATTTGTGACTATAAATATGCTCGTAAATCATCTTTAAAAGAACATTTAAGTTCTCACACAGGGGAGAAACCGTTTGTTTGTGAGACTTGCGATTATAAATGTATCAAAAAAGCAAATTTAAAAAGACATTTCAAAATTCACACTGGCGAGAAACCGTTTACTTGTGAGATTTGCGACTATAAAGCTGCTGAGAGCTCAAATTTAAAAGATCATTTAAAAACACATACAGGCGAGAAATCTTTTCTATGTGAGATTTGTGACCATAAATGTGTGCGCAGGTCAGATTTAAAATCGCATTTAACAACTCATACAGGAGAAAAACCTTTTGATTGTGAGCTTTGTGACTATAAATGTGCAAAACGATCAAATTTAAAAAGACATTTAAGAATTCACACTCGCGAAAAACCGTTTGCTTGTGAGATTTGCGACTATAAAGCTGCAGAAAGCTCAAATTTAAAAGATCATTTAAAAATACACACGGGCGAAAAACCCTTTGCATGTGAGATTTGTGATTATAAATGTGCGCGCAGATCAGATTTAAAAAGACATTTAAAAACTCACACAGGCGAAAAACCGTTTGGTTGTGAAATTTGTAACTATAAATGTGCACGTATGTCAAGTTTAAAGTTGCATTTAAAAATTCACACCTACAATGTTCTTCAGTGA
Protein Sequence: MENFNNILDSCKVEVKAEEFEDFNLEELHHSIDIKEEDEDRTALIKEKPAKNNGIRGKFFYCEICDYKYARKSSLKEHLSSHTGEKPFVCETCDYKCIKKANLKRHFKIHTGEKPFTCEICDYKAAESSNLKDHLKTHTGEKSFLCEICDHKCVRRSDLKSHLTTHTGEKPFDCELCDYKCAKRSNLKRHLRIHTREKPFACEICDYKAAESSNLKDHLKIHTGEKPFACEICDYKCARRSDLKRHLKTHTGEKPFGCEICNYKCARMSSLKLHLKIHTYNVLQ

Sequence clustering based on sequence similarity using MMseqs2