Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 7.4 3.4e+03 -0.9 0.1 24 45 79 100 76 109 0.60

2 8 0.052 23 6.0 0.1 21 49 104 132 97 135 0.80

3 8 0.072 33 5.6 0.0 21 49 132 160 129 163 0.86

4 8 0.001 0.45 11.5 0.1 22 51 161 190 158 191 0.87

5 8 0.052 23 6.0 0.0 21 46 188 213 185 218 0.88

6 8 0.0016 0.72 10.9 0.0 20 46 243 269 240 274 0.90

7 8 4.4 2e+03 -0.1 0.1 20 46 271 297 268 299 0.82

8 8 0.0011 0.5 11.4 0.0 21 45 300 324 297 327 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	7.4	3.4e+03	-0.9	0.1	24	45	79	100	76	109	0.60
2	8	0.052	23	6.0	0.1	21	49	104	132	97	135	0.80
3	8	0.072	33	5.6	0.0	21	49	132	160	129	163	0.86
4	8	0.001	0.45	11.5	0.1	22	51	161	190	158	191	0.87
5	8	0.052	23	6.0	0.0	21	46	188	213	185	218	0.88
6	8	0.0016	0.72	10.9	0.0	20	46	243	269	240	274	0.90
7	8	4.4	2e+03	-0.1	0.1	20	46	271	297	268	299	0.82
8	8	0.0011	0.5	11.4	0.0	21	45	300	324	297	327	0.92

Coding Sequence: ATGGATAGAACGCCAATTCTGGAACAGTTCCAGAAGATTCAAGAGATTACCAATGATTTCCAAATTAAAACAGAAAAAATTGAAGAGACGGAAATCAAATTGGAAACTCTGCATCATTCAGTGGATATTAAAGAAGAAGATGCTTTAATTAAGAACTCCAACTTGGATACCGAAGACGCTCCGACTGAAGCATGTGAATTGGATATGGGTGAGGTTCAATATCCTAAACCAAATCCCTTCGTTTGTGAAATTTGTAACTATAAATGCGCATATCGAGTCGATTTTGTGAGACATTTAAGAACTCACACTGGAGAAAAGCCGTTTTTTTGTGAAATTTGTGACTTTAAATGTGCCCGAAAGAGTAATTTAAAAGCACACTTACGAATCCATACCGGCGAGAAACCATTCACCTGTGAATTTTGTAACTACAAATTTACACAAAAAGGTTACCTAAAAACACATTTGCGGATCCATACAGGCGATAAACCGTTCACTTGTGAAATTTGCAATTTCAGATGTACTCAAAAAAGTAATTTAAAATCCCATTTAAAAATACACACCGGGGAGAAACCATTCACCTGTGACGTTTGCCACTATAAATGTGCAGGCAAGGATAAGTTGGTCCGTCATTTAAAAATTCATACTGGTGAAAAATTGTTTTCCTGTGAAACTTGCGACTACAAATGTGCACGCAAAGATAAGCTAAAACTCCATTTAAATACCCACACCAGCGAGAAATTATTTACCTGCAAAATTTGTGCTTCTAAATTTACACAAAAGAGTAATCTAAAAATGCATTTACGAATTCATCAAGATGAGAAACGGTTCGGTTGTGAAGTTTGCGGTTACAAAAGCTTTCAAAAAATTCATTTAATAAGACATTTAAAAATTCATACGGATGAAAAACCATACACATGCGAAATTTGTGGTCACAAATCGAGAGAAAAAGGAAATTTAAAAAAGCATTTAAGAACTCATACCGGATAG
Protein Sequence: MDRTPILEQFQKIQEITNDFQIKTEKIEETEIKLETLHHSVDIKEEDALIKNSNLDTEDAPTEACELDMGEVQYPKPNPFVCEICNYKCAYRVDFVRHLRTHTGEKPFFCEICDFKCARKSNLKAHLRIHTGEKPFTCEFCNYKFTQKGYLKTHLRIHTGDKPFTCEICNFRCTQKSNLKSHLKIHTGEKPFTCDVCHYKCAGKDKLVRHLKIHTGEKLFSCETCDYKCARKDKLKLHLNTHTSEKLFTCKICASKFTQKSNLKMHLRIHQDEKRFGCEVCGYKSFQKIHLIRHLKIHTDEKPYTCEICGHKSREKGNLKKHLRTHTG

Sequence clustering based on sequence similarity using MMseqs2