Basic Information

Insect: Rhagonycha fulva
Gene Symbol: Znf423
Assembly: GCA_905340355.1
Location: HG996560.1:4248743-4260760[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 22 9.6e-06 0.00028 22.0 0.5 1 23 84 106 84 106 0.97

2 22 0.24 6.8 8.2 3.3 3 23 114 134 112 134 0.97

3 22 1.1e-05 0.00032 21.8 5.9 1 23 140 162 140 162 0.99

4 22 0.00036 0.01 17.1 0.3 1 23 168 190 168 190 0.98

5 22 0.16 4.8 8.7 0.3 1 23 204 227 204 227 0.93

6 22 3.7 1.1e+02 4.4 0.3 2 23 258 280 257 280 0.92

7 22 1.7 50 5.5 0.2 1 20 322 341 322 342 0.93

8 22 0.03 0.87 11.0 0.0 1 23 437 459 437 459 0.97

9 22 0.00054 0.016 16.5 0.0 2 23 474 495 474 495 0.94

10 22 3.7 1.1e+02 4.4 1.6 3 23 505 527 503 527 0.76

11 22 1.8 52 5.4 2.7 1 23 532 555 532 555 0.96

12 22 0.31 9.1 7.8 1.8 2 23 619 641 618 641 0.95

13 22 3.8 1.1e+02 4.4 0.2 3 23 702 723 700 724 0.90

14 22 0.0013 0.038 15.3 4.4 2 23 735 756 734 756 0.97

15 22 0.004 0.12 13.8 0.3 1 23 765 787 765 787 0.97

16 22 1.1 30 6.2 1.5 2 23 795 816 795 816 0.97

17 22 1.1 32 6.1 0.1 1 13 862 874 862 878 0.86

18 22 0.035 1 10.8 0.2 1 23 925 947 925 947 0.95

19 22 0.11 3 9.3 1.3 1 23 954 976 954 976 0.95

20 22 0.0036 0.1 13.9 0.3 1 23 984 1006 984 1006 0.97

21 22 1.1 32 6.1 1.7 1 23 1013 1035 1013 1035 0.94

22 22 1.7 48 5.5 0.2 2 21 1068 1086 1067 1087 0.85

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	22	9.6e-06	0.00028	22.0	0.5	1	23	84	106	84	106	0.97
2	22	0.24	6.8	8.2	3.3	3	23	114	134	112	134	0.97
3	22	1.1e-05	0.00032	21.8	5.9	1	23	140	162	140	162	0.99
4	22	0.00036	0.01	17.1	0.3	1	23	168	190	168	190	0.98
5	22	0.16	4.8	8.7	0.3	1	23	204	227	204	227	0.93
6	22	3.7	1.1e+02	4.4	0.3	2	23	258	280	257	280	0.92
7	22	1.7	50	5.5	0.2	1	20	322	341	322	342	0.93
8	22	0.03	0.87	11.0	0.0	1	23	437	459	437	459	0.97
9	22	0.00054	0.016	16.5	0.0	2	23	474	495	474	495	0.94
10	22	3.7	1.1e+02	4.4	1.6	3	23	505	527	503	527	0.76
11	22	1.8	52	5.4	2.7	1	23	532	555	532	555	0.96
12	22	0.31	9.1	7.8	1.8	2	23	619	641	618	641	0.95
13	22	3.8	1.1e+02	4.4	0.2	3	23	702	723	700	724	0.90
14	22	0.0013	0.038	15.3	4.4	2	23	735	756	734	756	0.97
15	22	0.004	0.12	13.8	0.3	1	23	765	787	765	787	0.97
16	22	1.1	30	6.2	1.5	2	23	795	816	795	816	0.97
17	22	1.1	32	6.1	0.1	1	13	862	874	862	878	0.86
18	22	0.035	1	10.8	0.2	1	23	925	947	925	947	0.95
19	22	0.11	3	9.3	1.3	1	23	954	976	954	976	0.95
20	22	0.0036	0.1	13.9	0.3	1	23	984	1006	984	1006	0.97
21	22	1.1	32	6.1	1.7	1	23	1013	1035	1013	1035	0.94
22	22	1.7	48	5.5	0.2	2	21	1068	1086	1067	1087	0.85

Sequence Information

Coding Sequence: ATGATGTTTAAAGGCAATAGCAGCAGATTGGAATTGCTAATTGAGAAAATTCATAACCATAAAGGAAATTCGGAAATGGCTCATACAGTTTCGAGAGGATCAATTGGAACTGAACACGAAAGTTGGGGTTCCAACACTCCAGAACAAGCGTCACCAGCACCAAGTTCATGTCCAACCCCCTGTTCAAGTTTAAGCGATATTGCTGAAAGTGATGTTGCTTTCACTGTAGGAATTACAGAAACGACACCTTATGCATGCAAAATATGTAATAAGGCATTTGCTAGATCATCTTTATTAAGTAAACACGAACAGTCTCACACCGATCATCTTCAGTATGGCTGTTCATATTGCCCTCGCCTATTTAAACATAAAAGGTCTAGGGATCGTCATATTAAACTTCATACTGGTGATAAAAAATACAAATGTATGCATTGCCAAACTGCATTTTCCAGAAGTGATCACTTAAAAATTCATATGAAGACGCATGACAATAGTAAACCATTTCGTTGCCTCATTTGTAATCGCGGATATAATACGGCTGCTGCATTAACTTCTCATCAGCAAAGTCACTCAAAGCAAGTTGCAGATAGAAGTATTAGCCCTGAAAGTTTCAAATGCCTTCAATGTTCAGAACTATTTAGCGAATACGACCAACTTCAGATGCACGTCGCAAATGTTCATAACAATATTTTATTAAATTCATCATCACCAAATTTATCTGTAGCAAAACACGAAATAATTACAAATTCTCAAATAGAATTAACGAAATGGGTGTGCATGTACTGCAGTCGAGATTTTTTGATTATTGAAGAATTACAACATCATATCAACACCGACCATCAAGCTCTTGTCAATGGTAACTTTTTAGGAAATCATGGAAAAAATGCAGCTGATTCACCTTTAACACCAAACAACAACGACTTATCTTTAATAAACGACAGTCACTCAGATAGTGCACCCACTTACGCCTGTGAGAGTTGCACCATGCATTTTGATTCCGTCGATAAATTAAGGGTGCATGAAAATTGTATTCATTGGAAGCCACCTATCGCATCTTCATCTAAATCGTTCAATAAGGATTGTAGCCCATGCTTGCTTCCAACTCAAAATTTTAGTGGTAATGAAGGGTTAACTAACTCCAACAGTATTCAACCAATTCAACTGCAGCCTACCGATTTAAGTCGCAAGCGAAGAGGGGCCGATGTAGAGGAAAAAATTTCACCTAAACGAATGAACAATAATACGACCACCGTGCCAAATGTAACCAGTAGTTCTCATGATTCTTCCAAAAAGGAAGAGTGGACTAGCTACATATGCAGTATATGTGGAACTCAGCTACCAAATTTTGCATCCTTTATGGTGCACATGGATATTCACATGTCTGTTAGTGCAACTCCATCTAATGTTATCCTGGGAGGATACTGTCCCTTGTGTGGCGAAGCTTACAGAGATCAAACTGAACTTAATAATCATATTGTGCTACACACCTTAACCTACAAACTTGGATGGTGTTGTCGTGTTTGCAAAAAAGTTTTCAACGATAATTTGGAAGACTTTCAGCGGCACTTAATGGAAAACCATGCGTGTACGACATATAAATGTTGCGTTTGCGAACAACTTTTTGAATCTAAAACTGCTATGTTGATGCACTTAACCAAAAAACACAGTAATGAGTGTCAACATTTTCGTTGTAAGTTTTGTCCAGAACAAATATTCCATAACCAAATAAGTGCAGAAATGCACATATCTCAGCATGTACCACGCCTATTTAACCAAACTCGAAAGTCGTCCAATTATGGAGCTTATCCATTTCAAAATGAATTTAATGCTAGAGTGGGTTCGGTAAAAAGCTTGCAATGTCCGTTCTGTCGTCAATGCTTTAAAGGAGAATATTTACAACAAATGCATATTCTCAAGGATCACAAAGATTTTCTCGAGGCACACGGTTCCCGAGTTGCAGAGGAATGCTCTATAGATCAGCTGTCTTCTTCGAGAGGATCAAAGGAAGGACAGGCAAATTCACCAACTATTCCATTCACCAGTTCATTACCGTTATCAGAAAGTATGTCGAGATATGATAAAAGTTTAATGGAAACCATAATATGTGATATTTGTGGTTCTTCAGATTTCAACAACGATTCCGAATTAGCTGCTCATAAAAAACTTCACCATGTCAAGTCAAAAATTGGTCCTGTAAGCTTACAGTGTGCATATTGTAACGAACACTGCAAATCTCGTTCCGATTTAGAAAATCACATGAAAAATCACCAAATAAATAGCAACAAAGGTAAACATAAATGCAACATTTGTGACGAAATTTACTCCTCTGCCATAACTTTAGCCGAACATAAATTATCCCACTGTAAAATAGTGTCTGGAAACACATGCACTCAATGCAAAACTATTCTTTCGGACGAACAATCATTTTATTCTCATCAGCTAAAACACAGTTCAGTTTTGAACAAATCGAATGCTCAAATATCTCTACCAGCTAATTGTATAATTTGCTGCCAAACGTTACAAACAGACGTAGAAATTAAACTCCATGCTAATTTTCATCTCCAACACTTACTGCATAAGGAATACTTGTGCAATATATGCAATAAAATTTTTGATACTCGTACAGGAATCACAATTCCAAGTTACGAAAAAAATTCAGAAGGTTTACAGATTTCAGTGTGTAAAGAGTGTATTAATAAGTGTGGTAATAACAGCAGTTCCAATAGTCCAAGACTTACCAATATAAAAAGCGAAAATTTGGATAAAAAGATATATTCGTGCATAAAGTGTCCCCAGACGTTTGAAACTGAAAGCGAAGTAAAAAAACATGCTGCCACACATATTAGTGATCGAATTAACCACGAATGCCACATTTGTAGAAGCATTTTTTCAACGCCTCTGAAATTACAGTTGCATGTGATTGAGCACAGTTTCTTTGGTACAGGCCAATTTAGATGTTACATATGCAGTTCAGTCTTTACAACTGCAAATGGATTACTTTCCCATATGCTCGAACATGGAACTAACGCCAAACCTTACGAATGTGCTACTTGCCAAATGAAGTTCTTTTTCCAGACTGAACTGGATAACCACAAATACGAACACATTATTTCGCAAGCAGTTGCTCAATCAATAAACGTTAATAGTGTAGAAGAATCCGAAGTGTTAAATTCGGAAAAGTTAAAAATGGAACATTTAGGAAAGTGTCCATACTGTGATATGACAACATCGCATGTTTACTTAGATGTACATATAAGGTTTTGTTTACAAAATCCCGATATTAAAAAACGTCACGAAAATAAACGCAACGCAAAATTTGTAGAAAGCACAAATTCTGTTTCTGAAAGTGAGGATAAGGCTTTATAA
Protein Sequence: MMFKGNSSRLELLIEKIHNHKGNSEMAHTVSRGSIGTEHESWGSNTPEQASPAPSSCPTPCSSLSDIAESDVAFTVGITETTPYACKICNKAFARSSLLSKHEQSHTDHLQYGCSYCPRLFKHKRSRDRHIKLHTGDKKYKCMHCQTAFSRSDHLKIHMKTHDNSKPFRCLICNRGYNTAAALTSHQQSHSKQVADRSISPESFKCLQCSELFSEYDQLQMHVANVHNNILLNSSSPNLSVAKHEIITNSQIELTKWVCMYCSRDFLIIEELQHHINTDHQALVNGNFLGNHGKNAADSPLTPNNNDLSLINDSHSDSAPTYACESCTMHFDSVDKLRVHENCIHWKPPIASSSKSFNKDCSPCLLPTQNFSGNEGLTNSNSIQPIQLQPTDLSRKRRGADVEEKISPKRMNNNTTTVPNVTSSSHDSSKKEEWTSYICSICGTQLPNFASFMVHMDIHMSVSATPSNVILGGYCPLCGEAYRDQTELNNHIVLHTLTYKLGWCCRVCKKVFNDNLEDFQRHLMENHACTTYKCCVCEQLFESKTAMLMHLTKKHSNECQHFRCKFCPEQIFHNQISAEMHISQHVPRLFNQTRKSSNYGAYPFQNEFNARVGSVKSLQCPFCRQCFKGEYLQQMHILKDHKDFLEAHGSRVAEECSIDQLSSSRGSKEGQANSPTIPFTSSLPLSESMSRYDKSLMETIICDICGSSDFNNDSELAAHKKLHHVKSKIGPVSLQCAYCNEHCKSRSDLENHMKNHQINSNKGKHKCNICDEIYSSAITLAEHKLSHCKIVSGNTCTQCKTILSDEQSFYSHQLKHSSVLNKSNAQISLPANCIICCQTLQTDVEIKLHANFHLQHLLHKEYLCNICNKIFDTRTGITIPSYEKNSEGLQISVCKECINKCGNNSSSNSPRLTNIKSENLDKKIYSCIKCPQTFETESEVKKHAATHISDRINHECHICRSIFSTPLKLQLHVIEHSFFGTGQFRCYICSSVFTTANGLLSHMLEHGTNAKPYECATCQMKFFFQTELDNHKYEHIISQAVAQSINVNSVEESEVLNSEKLKMEHLGKCPYCDMTTSHVYLDVHIRFCLQNPDIKKRHENKRNAKFVESTNSVSESEDKAL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01294182;
90% Identity: iTF_00273027;
80% Identity: -