Rmax013946.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Resseliella maxima
Gene Symbol
MBD-R2
Assembly
GCA_029041755.1
Location
JAQOWM010000615.1:35964-39903[+]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 1.5e-18 2.8e-15 56.2 0.1 7 76 400 467 395 468 0.93
2 2 2.4 4.5e+03 -2.1 0.0 10 21 783 794 778 801 0.83

Sequence Information

Coding Sequence
atggtacaGCGAAAATGTTGTGTGTCTGATTGTAAATCAGCATCACATTTATCGGATTGTAGTGATGTGAAATTTCATGCATTTCCAACAAATGATGTTACACGAAATATTTGGCTTAAAAATTGTCgcattgaattaaatcgatcaaaaacaaaaactaatgTTGTTTGCTCACGGCATTTTCTAGAGTCTGATTATCAAGCACCAAAAAATGGACGAAAATTGCTTAATTTAAATGCTGTACCAACTGTTTTCTCATGGggcaatgaaaaatcattctcTGAACATTTAACagaaacacaaaattcaagCGTCACATCGGATACATCGAccaaagaaataataaataaaatatcaagtGAAACGACACCAATTGgtaaatcaaagaaaatgatgTCACGATCACAAGCAAATAGTGCCGCTGAAAAACAAAGATCAGCTAGCGCAGAGGagcaaacaacaaatgattcaaatacaaaagTAAACAAAGCAAGAAAATCATTGGATTCATCAACATCACCTGAAAAATCAACGGGAAAagataatattttgaaatcgccaagtaaaaaatttgatattgccATGCAACTTACACCTGGCTCTAAAGTTGAAGTTCAAGATTTAGCCGGAACCTGGCACAATGCCAGTATTGCTGAAGTTGATCAGGGTGAACAAGAAGTATTgattaatttcgaaaaaaatgtcaaatcaaaAGGTGCAGCTGGATTTAAATTGAACGATGAATGGATTGCAATGGATAGCAGTCGATTGCGAATTCcagttcaaattcaatttaaagcAGGTGATCGATGTTTGGCACGGTGGACTGATTCAAGAAAATTTCCAGCAACTGTAATCAAACCATTGGAAAACAACAAATATGAAGTACTTTTTGATGATGGTCTTGTTAAGCATGTAAAAGGGATTCATATGTCAAAAATTAagaaatcatcaaatgaaaaattggctCAATCAATAGATTCACCATTATCACCAGTGATGCCAATATCGCCTGTAACGCCAATTattaaaaaaccatttaaaattaatccaattccaaaatttgatttgagtaaattcaatttaccgGAAATTCCTGAAGGTGAATGGTGTTGTCCTTGGATAAATGATACACCAATCGGTGATGAAggttttttattgaatacagATGGTACAAAACGGCCAACAGTTTTAGTAAAAGATAATCGATTACCCGTTGGATGGACAAAACATTTGTATCAACGATCAAGTACATCAGGCAAATGGGATGTTGTACTTGTTGGTCCAAATAATAAACGATTTCGATCAAAGAATGATGTAAAAGTGTATTTAGAAGAAATTGGACAATCATACAATCCagatatttatgattttagcATTCATAAACGACGTGCCAAAGATATTGGTATTTATGTTTATACCGATGATTATGTACCACCAGTAATTCAAAAGCCATTATCATCtgaatttaaattggattCAAGTATTGATTCATCATTTCAAGATTTTAAACAAGAGCCATTCACTGGATTTTCACCAAATGAATCAACATCATCAATTCTATCGAAAATTAGCCAAGAAATTAAAGCTGAAACAAGTACACCAATTAAAACAGAATCAAATGttacaacaattgatcaaattgaaGAAGGTTTTATTTATGTTGGCGCATTAAAAGTTCAATTAgttgataatttatttcaatgccCAAAAGATGGATGCAATAAAAGTTTTCGCAAAGAAAATCACTTACAAATTCATGTAAAACATTATCATAGAGAATTATCACAGCAACTTGGCGCTTGCCCAAATATGACTGAATTGGCATATTTTCGTACAATGGGCACATCAATTGATGAATCATtgccaaaaaatcaaattccaaattcacaattttttgaaaaatcatttacatCCGAAATGAGAACAATACGAAAATCACAATCACCAACACGCATAAAAAccgaattaaaaattgatgaacaatCAAATACATTACCATTGGCCaatgaaaaaccattgaatgatggattaaaacgaaaattgaatacaaatcaaacaaatctGGAAGTGAAAGAGAAACGAAAACCATCGGCAAgtgataaaattatttcaccTGAATCTGTATCCAAGCTAAATACAATTAAAGATGATATATCAATGAATGACATTGAAATGAGTTCAATTGGTTCGACACcgattaaaaaagaaattggaaATGGTGCTGATTCAAAATTGGGTtcacaaaaattaatgataCCACGATTTAAAATTGGACCAACTGCCAAATTAAAAGGTAACAAAGTGTCACGacgaaaaggaaaaacacttaagaaaaagtttaaaaaattgGGTAAAGGTTTTAAGCGAAAAACgtatgaaatgattgaaaatcgattttcaaacatttatgaTGATGGAATTCAACGTGGTACATCAAATTTTGCTGCAATTCCAGCACAATCACGAcaaaatcgtttgaaatttttacaatattcatCAACTGATTCGAATTCAGAAAATTCAACTATGGATCCAAAGATACAACAACGTTCCAATTCGCATTACATTAAAGAAAATGGTGAAGTGATAAAAATTGTACGAATGCGTCAAGAGgaaattattaattgtttATGTTCATATGGTGAAGAAGATGGTTTAATGATTCAATGTGAATTATGCTTGTGTTGGCAACATGGTGGTTGCAATGGCATCGAAAAAGAAAGTGAAGTGcctgaaaaatatgtttgtttaatATGTAAAAATCCAGACAGAGCACGTGAATCGATGCGTTATATTCATGATCAAGAATGGTTATATGAAGGTAAATTATTTCATGCAAATTATCATCAACCAAGTCGACAGGCAGCATTGCGTTCAGATATTCTTAAGCAAAGTCATACATTGACCGGTAATCTATTGGAATTGAAGCGTTCATTGCATAgcttaaatgttaaaataaatattgcaaagaATAAAGATCATCCGAAAATGTATTTGTGGTCAAAAAAATGGGAACAAAGCCCACCGAgaaatattgattcaattgctgaaaaaaaaccaatattgAAACCAACCACTGAGCAAGTACCAGTTACATCAgatttagaaaagaaaaatcaaagtgTCAATAATACAGAATCAATCGAacaagaaaaacgaaaatctcaagatgaaaacaatgcaccgaaagatgaaaaattgaaagaaataactgatgcttcaattgaatcaaagacacaacaaaaagatgaaaatacgTCCACTGagaataacattgaaaaaaatgtgaatggcgaaacaaaaattgagacaacaacaacaactgcaGCACAACAACCAATCAAACAAGcaattattccaaaaaaagCGATTCGACAAACACCAAATATACCCGAACCAGAAGCTGCTATCGACTCTCTGGAATGTCAACATCGTCTCTTGGAGCACGttcaaaaagaacaaaatacgATTCTTTCAAGGATGCAAACCATTGAGGCACAAATCATTGCATTGGAATCAATGGATGATCATCCggatacaaattcaaattcagcAGCTGATTTTACAAGAACCAGTCAAACGATACGAATGCTGCTAAATGATttggcaaaaatgaaaaaattagcAGCaatcaatgaacaaaacaCAGCTTACAATTCAGTTGAATcatcaaattatatttga
Protein Sequence
MVQRKCCVSDCKSASHLSDCSDVKFHAFPTNDVTRNIWLKNCRIELNRSKTKTNVVCSRHFLESDYQAPKNGRKLLNLNAVPTVFSWGNEKSFSEHLTETQNSSVTSDTSTKEIINKISSETTPIGKSKKMMSRSQANSAAEKQRSASAEEQTTNDSNTKVNKARKSLDSSTSPEKSTGKDNILKSPSKKFDIAMQLTPGSKVEVQDLAGTWHNASIAEVDQGEQEVLINFEKNVKSKGAAGFKLNDEWIAMDSSRLRIPVQIQFKAGDRCLARWTDSRKFPATVIKPLENNKYEVLFDDGLVKHVKGIHMSKIKKSSNEKLAQSIDSPLSPVMPISPVTPIIKKPFKINPIPKFDLSKFNLPEIPEGEWCCPWINDTPIGDEGFLLNTDGTKRPTVLVKDNRLPVGWTKHLYQRSSTSGKWDVVLVGPNNKRFRSKNDVKVYLEEIGQSYNPDIYDFSIHKRRAKDIGIYVYTDDYVPPVIQKPLSSEFKLDSSIDSSFQDFKQEPFTGFSPNESTSSILSKISQEIKAETSTPIKTESNVTTIDQIEEGFIYVGALKVQLVDNLFQCPKDGCNKSFRKENHLQIHVKHYHRELSQQLGACPNMTELAYFRTMGTSIDESLPKNQIPNSQFFEKSFTSEMRTIRKSQSPTRIKTELKIDEQSNTLPLANEKPLNDGLKRKLNTNQTNLEVKEKRKPSASDKIISPESVSKLNTIKDDISMNDIEMSSIGSTPIKKEIGNGADSKLGSQKLMIPRFKIGPTAKLKGNKVSRRKGKTLKKKFKKLGKGFKRKTYEMIENRFSNIYDDGIQRGTSNFAAIPAQSRQNRLKFLQYSSTDSNSENSTMDPKIQQRSNSHYIKENGEVIKIVRMRQEEIINCLCSYGEEDGLMIQCELCLCWQHGGCNGIEKESEVPEKYVCLICKNPDRARESMRYIHDQEWLYEGKLFHANYHQPSRQAALRSDILKQSHTLTGNLLELKRSLHSLNVKINIAKNKDHPKMYLWSKKWEQSPPRNIDSIAEKKPILKPTTEQVPVTSDLEKKNQSVNNTESIEQEKRKSQDENNAPKDEKLKEITDASIESKTQQKDENTSTENNIEKNVNGETKIETTTTTAAQQPIKQAIIPKKAIRQTPNIPEPEAAIDSLECQHRLLEHVQKEQNTILSRMQTIEAQIIALESMDDHPDTNSNSAADFTRTSQTIRMLLNDLAKMKKLAAINEQNTAYNSVESSNYI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01288187;
90% Identity
iTF_01288187;
80% Identity
iTF_01288187;