Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.017 70 4.5 0.1 21 44 13 36 9 44 0.71

2 8 0.08 3.4e+02 2.3 0.1 21 45 41 65 33 73 0.80

3 8 0.12 5.1e+02 1.8 0.0 20 47 68 95 59 101 0.77

4 8 0.1 4.3e+02 2.0 0.1 21 44 97 120 90 125 0.72

5 8 0.055 2.3e+02 2.9 0.0 21 45 125 149 121 152 0.84

6 8 3.4e-05 0.14 13.2 0.1 18 45 178 205 171 208 0.90

7 8 3.1e-05 0.13 13.3 0.1 21 47 209 235 205 239 0.89

8 8 0.016 69 4.6 0.0 25 48 241 263 235 267 0.84

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.017	70	4.5	0.1	21	44	13	36	9	44	0.71
2	8	0.08	3.4e+02	2.3	0.1	21	45	41	65	33	73	0.80
3	8	0.12	5.1e+02	1.8	0.0	20	47	68	95	59	101	0.77
4	8	0.1	4.3e+02	2.0	0.1	21	44	97	120	90	125	0.72
5	8	0.055	2.3e+02	2.9	0.0	21	45	125	149	121	152	0.84
6	8	3.4e-05	0.14	13.2	0.1	18	45	178	205	171	208	0.90
7	8	3.1e-05	0.13	13.3	0.1	21	47	209	235	205	239	0.89
8	8	0.016	69	4.6	0.0	25	48	241	263	235	267	0.84

Coding Sequence: ATGGAACTATCACAAGAGCAGTTAGGCAATCACTCAACCGAGAAACCGTTTCATTGCCCACTTTGCGATAAGACCTTTTCAAGGAACGCAGGTATGAAGGTGCACTTAAGGTCCCATACCGGGGAGAAGCCGTACCCCTGCAACGTCTGCGAAAAGACATTCGCGTCCACCCACGGCCTCAAATACCACTTAAGCTCCCACTCCGGCGAAAAGCCATATTCTTGTACATTGTGCGACAAGACGTTCGCCAGGGGCGATTATCTGAAGTTGCACATGTCTATTCATACCGGCGAAAAGCCGTTCCCTTGCACGATTTGCGACAAAACGTTTTCTTCGAGGATGCGACTAAAAGTGCACTTAAGGAACCATGCCGGGGAAGAGCCGTTCTCTTGCACAATTTGCGACAAAACTTTCTCTAGCGATGGGGCCTTGAAGAGCCACTTAACGATTCACGCCGGTGAAGAACGGTTCCCTTGCACTCTTTGCGAGAAGAAGTTCTCCACGAATAAGTACCTGAAGAATCACCTAAAGAGGCATTCCGGGGAAAAGCCGTTCTCGTGCACGATTTGCAATAAGCTGTTCTCTGCCAATAGGAACTTGAAGAGTCACCTACGGAGTCACGCTGGGGAAAAACCGTTTGCGTGCATTATTTGCAATAAGAAATTTGTTGCGAAGAGGAACTTGAGGAGTCACCTGCGACTGCATGCTAGCGATGAGTTGCTTtcgtgtacaatttgcgaTAAAAAATTTACGAGGAATGACAATTTAAAGAAGCACTTTGAACGTCATACTGGAAACAAGGATAAATga
Protein Sequence: MELSQEQLGNHSTEKPFHCPLCDKTFSRNAGMKVHLRSHTGEKPYPCNVCEKTFASTHGLKYHLSSHSGEKPYSCTLCDKTFARGDYLKLHMSIHTGEKPFPCTICDKTFSSRMRLKVHLRNHAGEEPFSCTICDKTFSSDGALKSHLTIHAGEERFPCTLCEKKFSTNKYLKNHLKRHSGEKPFSCTICNKLFSANRNLKSHLRSHAGEKPFACIICNKKFVAKRNLRSHLRLHASDELLSCTICDKKFTRNDNLKKHFERHTGNKDK

Sequence clustering based on sequence similarity using MMseqs2