Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 5.4e-19 8.6e-14 54.4 0.0 9 50 67 111 59 114 0.78

2 3 0.48 7.7e+04 -3.0 0.0 15 23 122 130 118 132 0.74

3 3 0.31 4.9e+04 -2.4 0.1 5 15 202 212 201 226 0.69

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	5.4e-19	8.6e-14	54.4	0.0	9	50	67	111	59	114	0.78
2	3	0.48	7.7e+04	-3.0	0.0	15	23	122	130	118	132	0.74
3	3	0.31	4.9e+04	-2.4	0.1	5	15	202	212	201	226	0.69

Coding Sequence: ATGTTCACCTGTGGTTGTGTTTTTCATTTGGCAGCGGGCGGTAGCAGCCATGAGGGGGGTGGGAGTGATGCGGGGGGCAAGTGGGCCCACAGCGACCGTGATGATGGAATTGTGGGTGGGTCAGATGGAGGGGGAGATGATGGGGATGACGTGAAGGTTGGAGGTGGCCAGCAGAGGGCAGCGTCCGATGGTGAAGCGCCAACAGGCACCAACGGAGAGGACTCAGCCAAAAAGAGTGGTGTCAGTGACCAGCCAGCTATTTGTCCCCTCTGTGGTGCAACCATCAGGCAGTCGAGGAACCTCCGACGACATCTCGAGCTTCTACACTTTGGTGCATCTACGACACGTGGGGGGTCACTTCGGGTGAAATCTCGGTCGTTCAGCCATCAGTTGacgagggtgggggaggggacgAGGGAGGGCAGTTCGTCCCCCATCTCCCTTGTCTCGCCACACCAGCCCGCTGTCTCCATGGTCATACCCGCCAACCCGTTGATGGTGGTCAGCAGTGGGGACAGGTTGGGCCCCGGTGACCCATCTCATGGGCTTCTTGGACACCTTCCGCATCCTTTATCAATCCCCATGCCCACTGACCTCATGCTCAGGAGACACCATGACCCGGACACGAACTCTCCTGTTTACACAGATTCGAGGACAACTCGAGGTGAAAGCCCATCAGCCAGTACGTCCCACTCAGCCGTCGGTGGGGACGTTGTCTGA
Protein Sequence: MFTCGCVFHLAAGGSSHEGGGSDAGGKWAHSDRDDGIVGGSDGGGDDGDDVKVGGGQQRAASDGEAPTGTNGEDSAKKSGVSDQPAICPLCGATIRQSRNLRRHLELLHFGASTTRGGSLRVKSRSFSHQLTRVGEGTREGSSSPISLVSPHQPAVSMVIPANPLMVVSSGDRLGPGDPSHGLLGHLPHPLSIPMPTDLMLRRHHDPDTNSPVYTDSRTTRGESPSASTSHSAVGGDVV

Sequence clustering based on sequence similarity using MMseqs2