Pnym154846.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Pyrrhosoma nymphula
Gene Symbol
-
Assembly
GCA_963573305.1
Location
OY754340.1:27099621-27104835[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 4.8e-05 0.041 17.4 1.6 1 23 230 252 230 252 0.98
2 13 5.7e-07 0.00048 23.4 1.7 1 23 258 280 258 280 0.98
3 13 3.2e-08 2.7e-05 27.4 0.5 1 23 286 308 286 308 0.98
4 13 1.4e-07 0.00012 25.3 0.8 1 23 314 336 314 336 0.99
5 13 8.6e-07 0.00073 22.8 1.2 2 23 343 364 342 364 0.97
6 13 0.00069 0.58 13.7 0.7 1 19 370 388 370 391 0.96
7 13 1.7e-05 0.015 18.7 3.5 2 23 407 428 407 429 0.95
8 13 0.0003 0.25 14.8 6.9 1 23 553 575 553 575 0.98
9 13 1.7e-06 0.0014 21.9 1.5 1 23 581 603 581 603 0.96
10 13 0.00011 0.094 16.2 0.3 1 20 609 628 609 630 0.95
11 13 0.00014 0.12 15.9 1.4 1 23 713 735 713 735 0.98
12 13 1.1e-05 0.0095 19.3 3.5 1 23 741 763 741 763 0.96
13 13 1.4e-06 0.0012 22.2 1.3 1 23 769 791 769 791 0.98

Sequence Information

Coding Sequence
ATGACCGACATGCTTCTTGCATCTTTGGTAAAACGGACTGTTATGGGAGAGCAGCACACAGCGTTTGAACGCAGAGAGGTCCACGTGGAAGATGGAGAAGGCGAGGCAAGAGTCGAAGCCGGGAGTATAGTGTGCGATGGCGTGGAGCCTCAAGGACATCATCCGGTGGTCAGCAGGAACAGGCTGACCGTTTGCGACGGGTCCACCGACTTGGATGACCGCCTCGGAGGGAGTGGCACCAAGGGACGCGAAGACTTCATGTGCGCCGTCTGCGAGGAGATATTCCTGGACATGCAGAGCTTAAGGGGTCACCTGCCCTGCAGCTCCAGTTCCGGCGTGACCCTCGCAGCCGCCGCTGTTGACCACGGCGAATTCGGTGTCGGTGGAGGTGGCGGTCATTGGGACAGTGTCGGTTTGGAGGGCGGACAGGACGCGATGATGACCAGCCGGGTGAAAGATGAGTCCCCGACAGGCGTGCCAGGGTTCGCTCAGGGCGGCGAGACGGGTGGCTACTCTGGCAACACTTCGGAGAATGCGTTCGTCCACAGGCGGGTTCGGGGTGGCATGACCAGGGGGGTCAGGGGCAGGAAACCGAGTCTAGTAGCGCGGCCTCGGAACGTCAAGAGCAGCAACCTGATGGTCGGGCCCAAACTCTCCGACAACTTCACCATCGACAAGAAGGTTTCCTTCCAGTGCGACATGTGCCGGCATGGTTTCCCGAGACTCGAACTGCTGAAGAAACACATCCAGTCCCACTCTGAAGAGGGCGGTTACGCATGCCCGATCTGCCGCAAGAGCTTCCGGACGCGCTGGAGTCTGAAGAACCACAGGAAGTCCCACCAGAAGGTGTCGCAGTACGAGTGTCCGATCTGCGGACGGAAGTTCTCGCGTCCCCAACACCTCGAGGCTCACAGGGCGACGCACGGTACTGGGACGGAGTACCAGTGCGGCATCTGTCGCAAGACCTTCCCTCAGAGCAGTTACTTGGAGATGCACCTGAGGACTCACGCCGGTCAGGATGCGACCCAGTGTCACATTTGCGGGAAGAGGTTCAGCAACGCAAACGTCCTCAAAGTGCACCTCCGCGTCCACATGGACATCAAGCCGTTCAAGTGCGAACTTTGCGAGATGCGGTTCGCGCACAAGGCCGAACTGAAGCAACACAACCTGTACCCTTGCGAGGCAGAGCCTGCGTCTCACTCTCACCAGGGTTCGAACCGCTGCCATCTCTGCGGGGAGTGCTTCGTGGATAGCGGTGGCCTCACTCGGCACATTGAGTCTCACCATCCAGAAGTGAATAAGAATAAGGAGTTCAAGCCGGACCCCGATGATCTTCCGTCCCAGTCCGGTGCGCCGATGAGCACCACCTCCGGTGAGCCTCACCCCTTGAATGTTCCTAAACTCAGAGCGCGAGGCGGGGTGCCTCGCGAGAGCCTCAACACGGGTATGAGttacgaggaggaggaggagggtttgaGGTTCAAAACCTCGCCAGATTCCGACTCCGAGACGGAAACGAAGGCGAACGCTGATCCAGACCCGGATTTTGTTCCGGGTTTGACTTCCGACGAGTCCGCATCCACGTCCGACGTCACCTACAGGCCTCCGGAGGTGGAGCGCCCTGGGGAGACGGGCGGGGGGACGAAGGTCAGGCCTTACAAGTGTCAGATCTGCCACAAGTGCTTCGGGGAGAAGTGGGAACTGAACAGTCACCACCGCCTGCACACCCAGTCCAACCCGCACGCCTGTTCCGTTTGCGGCAAGCGATTCACGGAGACGGTGAACTTGCGCAAGCACATGTTGATGCACGTGGACAGCAGGCCGTTCGAGTGTCCGTTCTGCGCGAAGCCGTTCACGCTGCGCAAGAACTTGAAACGACATCTTGAGCTGGAGTCTTGTCTGAAGCGGTTGGATTTCAACGCCAGCGAGTTGGGACCCGTAGGGGGCGGTGTCCAGGGTAATAGCGGTAATAGGGACGGACAGAACCCTAACGACGGCGGGGCGGACAGGGGCTTCGGTGACGCGTCGTCTGGGGAGAACCCTGGCAGCTCCAGGACCCTGGACGACATAATGGCAGCCGCCAAAGAGGCGAGTGTCGAGGTTTACCTGGAACAAGAAGGCTCTGTCAGCAGGGTCTTCCCGTGCACCTTTTGCGAGAAGACTTTCCTGAGGACGGACCAGTTGAAGAAGCATTTGATGGTGCACGGTGGTATCAAACCTCACGCTTGTACCCTGTGCAGTAGGCGTTTCACCGAGAAGGGCAACCTGTCCAAGCACATGAAGACGCACGCTTACGAGAAGCCTTATCCCTGCAAGTTCTGCGAGAAGGCCTACACGCAGAAGAAGAATTTGGAGaggcacttgctttcgcaccagAGTGATGATGAATCGGCCGGGTGA
Protein Sequence
MTDMLLASLVKRTVMGEQHTAFERREVHVEDGEGEARVEAGSIVCDGVEPQGHHPVVSRNRLTVCDGSTDLDDRLGGSGTKGREDFMCAVCEEIFLDMQSLRGHLPCSSSSGVTLAAAAVDHGEFGVGGGGGHWDSVGLEGGQDAMMTSRVKDESPTGVPGFAQGGETGGYSGNTSENAFVHRRVRGGMTRGVRGRKPSLVARPRNVKSSNLMVGPKLSDNFTIDKKVSFQCDMCRHGFPRLELLKKHIQSHSEEGGYACPICRKSFRTRWSLKNHRKSHQKVSQYECPICGRKFSRPQHLEAHRATHGTGTEYQCGICRKTFPQSSYLEMHLRTHAGQDATQCHICGKRFSNANVLKVHLRVHMDIKPFKCELCEMRFAHKAELKQHNLYPCEAEPASHSHQGSNRCHLCGECFVDSGGLTRHIESHHPEVNKNKEFKPDPDDLPSQSGAPMSTTSGEPHPLNVPKLRARGGVPRESLNTGMSYEEEEEGLRFKTSPDSDSETETKANADPDPDFVPGLTSDESASTSDVTYRPPEVERPGETGGGTKVRPYKCQICHKCFGEKWELNSHHRLHTQSNPHACSVCGKRFTETVNLRKHMLMHVDSRPFECPFCAKPFTLRKNLKRHLELESCLKRLDFNASELGPVGGGVQGNSGNRDGQNPNDGGADRGFGDASSGENPGSSRTLDDIMAAAKEASVEVYLEQEGSVSRVFPCTFCEKTFLRTDQLKKHLMVHGGIKPHACTLCSRRFTEKGNLSKHMKTHAYEKPYPCKFCEKAYTQKKNLERHLLSHQSDDESAG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00307093;
90% Identity
-
80% Identity
-