Pumb010426.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Pyrrhia umbra
Gene Symbol
-
Assembly
GCA_963891755.1
Location
OY982923.1:5270563-5294572[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 8.5e-13 3.7e-10 40.8 0.1 9 108 372 467 365 469 0.90

Sequence Information

Coding Sequence
ATGTCAATGTTtggaataattttaagcttgacAAGACTTCTACAACGACATGAACATCAACTGTCAAAAATTTTAAAGGAGTCTTgggaatttataataaacttaaaaacattAGTAGCTACAATATGGTTCATGTTCCTGTATTACTCGTTTAGTGTATTTGAAATGCAAAGAAGTATTAGTTTGGAAAAAATAAATGATACAGAAGTGGTGTCAAATGCAAGAAATACTGCACTCAGACATAACTCACCAGACGTTATTATACCTCAAAGAAGAAGATTCAGACCAGTAGGGAGCATATTTGAACAATATTGTATAACTATTAAGCCAAAACTATACAGGAGCAGCTCCTTGTCCGATCTGACTGCGCATTCAAGTGATTTCACACTAGACTACTTCAAGAACAGAGTTCAAGCTGAAAATAAACGCAAAGAATCATACTTCAATAGCTCTGGCGACGCTGACACAAAACACTGTAGAATCCACACCGACACATTAATGTCGTGGAACTTTAAAGGGAAAAAGCCGAAGAAGAAATCTGAAATGTCTCCAGAGTCTTATGCGTCCAAGTTTGCCGtcgaatatttaaatacttttcaGAGAGAGGACATTGACCCAAACGCTTCGTCGTGCGCAGACAATTCCAGTATCGAAAGCACAGATCAATTGGGTATTCAGAAAGGAGCTGCTTTCCCCTTTAAATCGACCCCAAGCGGTAATCTGAAAGTTCAGTCGAATCAAgtAGTATTTCAATCGTCCACGGTAGGTGTTTTATTAGCGGATCCCACGCAAGCTAAGGTGAAGGTGAAATTCGAAGGGAAAGCGGGAGCCGAACCTGACGATGAATTATCACAAAACTTTGACCACGATATAGATTCAGAACCACAACTACAATTTGGACCTAGAGAAACGCTCAACGCGAATGTTCAAGGAAAAAGCACTTTACCGGGTGATCGGATTGGAAGATCAAAACCGTCATGTGTTAGAGAAGATAAAGGCAAGGACTTGGGCAGTCTCGGATATGCAGTAGCAGAGCCTATAGACTGGATGCGAGTTCAGCTACCTAAGAAACAAGATCTATTTCAAGAGTTTTATCGAAgaattcataattatatAAACACTGATACTGTGATACATATCGGCGATGAGGAGTTCCACTGTCACTACATAGTGTTACAAGTTTACTCCTCCTTCTTTGACATGAACCCGCATAGAGAAATTGAACTGCCTATTGCCAACGTAACGCCTGAAGCTTTCCAGACAATTTACGAATGGATGATTTTTAATGGTGTTGAAAGTAACAAGCTGCTTAAAAGGGACAATATCCTAGATTTGTTTTATGCTGCGCAGTATCTTGCTATTAAAGACTTAGAAGACCAATGTTGGTCGTTTATTGTGAATGAGAACCTTTTCTCTGAAGACACAGCATTCGCGTTATTCAGGGAAGCGAGGAAGAAGGGAATGACACCGGTTATGGATTTAATGgtcCCTCGTGTGATGAGATTTTTCCTACCACTCGTTGCGTCAAGAGACTTTATCGATCTAGAAACAGAAGAGCTAATGATATTTCTGAAATCGAACTACATATCTGTCACGAGTGAGATTGAGGTCTTAATGGCTGGCGTGCGTTGGCTGTACGGAGACTGGTCATCTCGGCGCCGGTTCGCGGTCGAAGTGATGCGGTGCGTACGTTTCGGCCTCATCTCTCCGTGGCAGCTCGTCGATATAAAGAGGAACCCTGATAACGCAGAGATATTGGAGATAGTTAATGAACCAGAAGTACAGCAGATGGTCGATGATGGACTAGCCtatgtaataataaagtatTGGTATGGCAACAACTCTAAGAACTACTACCACTGGATCGATGTGCTTGGATTGACAGAACCCGCTGAGAGAAACTGGATTGGCGAGGAAAAGAATCATGTAACATACAAGGATTTCCTGAAGTATTTGGAACAGTTCATGGTTCCCAAAGACCAGATGTACCAACAGATGGCCATGATGCAACCGCCGAGGAGGAACGATGACAATATACCAGGCAGTATGCGAGGTATGGACAGCGAAAAAATGGAAATGCGACGCCCCAAAATGGACTTTCCATTGCCAGCTACACTGAAAGGACTGGCCGGTGACAAGGATAAATCTTTTCCGACAATGAGTGAATTTTTTGAAAATCGAAGAAAGAATCAAGAAGGCCAGCAATCTGTTTCTCCATCTAACAGATCACCACCCTCGGTGGATGTGGAAATGGCAATGCAGATGCCTATTGTGACAGAACCCAGAATGAGGGGTCCCGAACTTGCTTGTAAACATCAAAAGCAATTCGAGGAGCAAAGAAAACAACTAGAACATCAGAAACAACAATTGGAGCTAGCTCAACAACAGCGACGCAAACAAATCCAACAGATTCACATGTGCACCATTGAACAAGACacaACTTCAAACAAACATGAGCAAATATATGATCCACCCGAGAAGGACTCCGCTGAAGACCTGAACACGACCAACAGTGAGACTAGCAGTGGAACTGTCGAGACCAGCATTACTGATAAAAATCAGTATGCGATGAGAAGATCAGAGAAGAGGCACAGTGTGGCAGCCTCGTACCTCGCCGCGGCCACTGCTGCTTTGGCAGGCTCCAGAAGCCCGACGTCCGGCCCTCGCGCACAAGCAGCGACAAACGCGTCGCGGTCGGAGGCGACGCCGCGGCCCAACGCGCCCATGTCACAGAACAATATTGGAAGCCCGCAGATATCACTCTTCAATCAGTCCAAGGAGTCCCTGGCCAAGACTAATATGAACAAGCTATCCACTTCCATATTGGGCCCTTCAAACAAGAATTACATAGCTGAAGGTTCCTTGTTCAACTGGGACAGAGAGACTGTGCTAGTTTTTGGTGGAATAGATCTCCTTACTACTTATGGATTCGGAGGAAATACTGGGAAATACATTTATAGATTCGATCCAGTGACCAACGTGTGGGACTATGTAGGAGATCTGCCTGAGCCAAGACATCATCACTCGGTCGCCTTCTTAAGAGGTCGGGTATATCTTGTCGGTGGTGCAGATCCCCGCGATGACGACATCAGGGGGAAGTCGGCCGTAGTGTCCACCGTGTGGAGCTTCGAGCCGGTTTCACGCTCCTGGTACAGTGAAAGTGGACTCATGACGCCCAGAAAGAACTTTGGTCTCGTTGTACATCGCATGGCTATGTATGCTATTGGTGGACTAGATAAAAAGGGCAGGGTTCTTCGGTCGGTTGAAAAGTTCGATCCTAAAACGGGTTCTTGGAGTGAGGTGCGTTCGATGAGCGTGTGTCGGATGGCCGTCGCTTGCGCGAAGTACCGTGACTACATCTGGGTTGCCGGTGGCATGACTGGGGATAAGAAGAAGCCAGTTTGTAAGATTGTCGAGTGCTATAACTCCAAAACTAATGAGTGGACAGAAATACACAGTCTACGGTTTCCCAGATGTTTCTCTACAATGTTTGCGATGAACGATAAATTATATATAGTCGGTGGCGCTGGAAAGATTTCGGATAAGGAAAAGACAGTTAGCAGTGTGGGAGCGATAGATGTATGGGACTGGCAACTGCGCAAGTGGAAGCAAGAGACGGAGATGTCGATGCCCAGACATGGACATGCACTAGCATATCTCGGAACACAGCTCTTCATCATTGGTGGTGTGACAACGATTTACATGCGAGCGTTGAATAACGTGGAGTCGTTCTGCTGCGAGCGCGGAGCTTGGATACGGGGAGTGGCCACGCTGCCCTCGCCGCTGTCAGGTCACGGCGCCGTCACACTGCCACCCGCTTCACTGATGTGA
Protein Sequence
MSMFGIILSLTRLLQRHEHQLSKILKESWEFIINLKTLVATIWFMFLYYSFSVFEMQRSISLEKINDTEVVSNARNTALRHNSPDVIIPQRRRFRPVGSIFEQYCITIKPKLYRSSSLSDLTAHSSDFTLDYFKNRVQAENKRKESYFNSSGDADTKHCRIHTDTLMSWNFKGKKPKKKSEMSPESYASKFAVEYLNTFQREDIDPNASSCADNSSIESTDQLGIQKGAAFPFKSTPSGNLKVQSNQVVFQSSTVGVLLADPTQAKVKVKFEGKAGAEPDDELSQNFDHDIDSEPQLQFGPRETLNANVQGKSTLPGDRIGRSKPSCVREDKGKDLGSLGYAVAEPIDWMRVQLPKKQDLFQEFYRRIHNYINTDTVIHIGDEEFHCHYIVLQVYSSFFDMNPHREIELPIANVTPEAFQTIYEWMIFNGVESNKLLKRDNILDLFYAAQYLAIKDLEDQCWSFIVNENLFSEDTAFALFREARKKGMTPVMDLMVPRVMRFFLPLVASRDFIDLETEELMIFLKSNYISVTSEIEVLMAGVRWLYGDWSSRRRFAVEVMRCVRFGLISPWQLVDIKRNPDNAEILEIVNEPEVQQMVDDGLAYVIIKYWYGNNSKNYYHWIDVLGLTEPAERNWIGEEKNHVTYKDFLKYLEQFMVPKDQMYQQMAMMQPPRRNDDNIPGSMRGMDSEKMEMRRPKMDFPLPATLKGLAGDKDKSFPTMSEFFENRRKNQEGQQSVSPSNRSPPSVDVEMAMQMPIVTEPRMRGPELACKHQKQFEEQRKQLEHQKQQLELAQQQRRKQIQQIHMCTIEQDTTSNKHEQIYDPPEKDSAEDLNTTNSETSSGTVETSITDKNQYAMRRSEKRHSVAASYLAAATAALAGSRSPTSGPRAQAATNASRSEATPRPNAPMSQNNIGSPQISLFNQSKESLAKTNMNKLSTSILGPSNKNYIAEGSLFNWDRETVLVFGGIDLLTTYGFGGNTGKYIYRFDPVTNVWDYVGDLPEPRHHHSVAFLRGRVYLVGGADPRDDDIRGKSAVVSTVWSFEPVSRSWYSESGLMTPRKNFGLVVHRMAMYAIGGLDKKGRVLRSVEKFDPKTGSWSEVRSMSVCRMAVACAKYRDYIWVAGGMTGDKKKPVCKIVECYNSKTNEWTEIHSLRFPRCFSTMFAMNDKLYIVGGAGKISDKEKTVSSVGAIDVWDWQLRKWKQETEMSMPRHGHALAYLGTQLFIIGGVTTIYMRALNNVESFCCERGAWIRGVATLPSPLSGHGAVTLPPASLM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01363285; iTF_01361824; iTF_01538949; iTF_00383878; iTF_00786152; iTF_00017513; iTF_00636681; iTF_00050125; iTF_00909039; iTF_00745969; iTF_00405180; iTF_00120701; iTF_00018335; iTF_00450335; iTF_00282599; iTF_00281556; iTF_00677831; iTF_01026504; iTF_01085570; iTF_01260296; iTF_00758443; iTF_01339115; iTF_00123553; iTF_01062049; iTF_00623011; iTF_01031299; iTF_01028490; iTF_01030418; iTF_01064836; iTF_00041967; iTF_00041069; iTF_00043740; iTF_00040062; iTF_01094227; iTF_01441268; iTF_01095127; iTF_01340408; iTF_00924953; iTF_01532281; iTF_01084446; iTF_00121631; iTF_00124458; iTF_00122591; iTF_00425624; iTF_01247295; iTF_00039020; iTF_00042828; iTF_00147697; iTF_00906348; iTF_00185485; iTF_00186450; iTF_00172015; iTF_00622159; iTF_01073771; iTF_01180464; iTF_01179643; iTF_00831407; iTF_00300417; iTF_00850954; iTF_00952010; iTF_00851990; iTF_00772190; iTF_00888446; iTF_01027519; iTF_00000497; iTF_00637865; iTF_00001335; iTF_00784562; iTF_00783703; iTF_00785365; iTF_01063923; iTF_00302308; iTF_01534120; iTF_01063000; iTF_01533243; iTF_00685629; iTF_00712105; iTF_00301376; iTF_01173461; iTF_01426070; iTF_00374391; iTF_00173249; iTF_00447428; iTF_00445382; iTF_00364216; iTF_01192887; iTF_00273784; iTF_00809342; iTF_00810282; iTF_00274586; iTF_01425276; iTF_00952864; iTF_00327232; iTF_01487876; iTF_01221770; iTF_00908096; iTF_00907214; iTF_01029440;
90% Identity
iTF_00783703;
80% Identity
-