Pumb023501.1
Basic Information
- Insect
- Pyrrhia umbra
- Gene Symbol
- Lztr1
- Assembly
- GCA_963891755.1
- Location
- OY982938.1:9107736-9122918[+]
Transcription Factor Domain
- TF Family
- BTB
- Domain
- zf-C2H2|ZBTB
- PFAM
- PF00651
- TF Group
- Zinc-Coordinating Group
- Description
- The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 5.9e-15 2.6e-12 47.7 0.0 4 109 364 499 361 500 0.85 2 4 2.8 1.2e+03 0.5 0.1 77 108 499 530 497 532 0.86 3 4 7.3e-17 3.2e-14 53.9 0.0 10 96 597 683 592 698 0.87 4 4 1.3 5.6e+02 1.6 0.0 77 106 698 727 687 730 0.80
Sequence Information
- Coding Sequence
- ATGCAAAACCTAGGGAAGATGATAACTGAGCAGCTGCGCAATCCAAATGAGCTGGACATCAGCCTCCGGATGGAGTTCGGACCATTTGAGACCGTGCACAAGTGGAAGCGGATGTCGGAGTGCTACGAGTTTGTGGGGGCCAGacGCAGTAAACACACAGCCGTAGCATACAAAGACGCGTTATACGTGTTCGGTGGCGACAATGGCAAGTCCATGCTCAATGATCTGATCAGGTTTGACATCCGGGAGAAGTCTTGGACCAAGACTGGGTGCATGGGGGTCCCGCCTGCGCCGAGGTACCATCACTCTGCTGTGGTACACCGGTCGTCAATGTTCGTGTTCGGCGGATACACAGGGGATATCCTCGCCAACTCCAATCTGACGAATAAGAACGATCTGTTCGAGTACAAGTTCCCCAGCGCGCAGTGGGTGCAGTGGAAGTTTACTGGCCAAGAACCAGTGCCTCGGTCAGCACACGGAGCCGCAGTGTATGACGACAAGCTATGGATATTTGCTGGCTATGATGGCAATGCGAGGCTCAATGATATGTGGACTATTAATCTATTGGGTGAGAACCACCAATGGGAGCGCATAGAACAGAAGGGGCAGTGTCCCCCCACTTGCTGCAACTTCCCCGTGGCCGTCGCTAGGGGCAAAATGTTCGTGTTCAGCGGACAGAGCGGGGCCAAGATCACGAACGCACTGTTCCAGTTTGATTTCGAAACGCATACCTGGAGCCGCGTGTGCACGGAGCACCTGCTCCGCAGCGCGGGCGGCGCCCCGGCGCGGCGCTACGGGCACGTGATGGTGGCCCACCGCGCCCAGCTCTACGTGTTCGGCGGCGCCGCCGACAACACGCTGCCCAACGACCTGCACTGCTACGACTTGGACACGCAGATATGGTCCGTAGTTCAGCCCCCAACAGACTCGCAGATCCCTTCAGGGCGGCTGTTCCACGCAGGCGCGGTGGTGGGTGACGCCCTCTACATCTTCGGTGGAACTGTGGACAATAACGTGAGAAGTGGCGAGTTGTTCAGATTTCAACTATCAAACTACCCTCGTTGCACCCTCCACGATGACTTCGGTCGCATACTGAAGTCCCACCAGTTCTGCGACGTGCAGATACTGGTGGGCCCGGAGAAGACGCCCATATTGGCACACCAGGCCATATTGGCTGCCAGGTCGCAGTTCCTCAGGACTAAAATCAAGGAAGCTAGAGACGAGCTAACGAAGCGCATAGCAGCAGGCGAGGAGGAAGCTTCAGAGATATCTTACAAGACGCCGCCGCAGCTGTCCATACTCCTGCCCGAGGCCACACCCGAAGCCTTCAACATGGTGCTCAACTACATATACACTGACAGGATCGATCCTACTGAGAAAGACGAGGACCCGGCGTCCCCGGCGACGGTGCTGCTGGTGCTGTCGGTGCTGCGGCTGGCGCTGCGGCTGGGCGTGCCGCGGCTGCGGGGACTGTGTGCCAGGTTCCTGCGCGCCAACCTGTGCCTGGCCAACGTGCTGCAGGCGCTGCATGCAGCCCACCACGCGCAGCTGCACTGCATCAAGGAGTACTGCCTCAGGTTCGTGGTGAAAGACTACAACTTCACTCCCATAGTGATGTCGAAGGAGTTCGAGGAGATGGAGCAGAGCCTCATGGTGGAGGTGATCAGGAGACGGCAGCAGCCGCCGCCCAAGCCGGCTAATGCCGCCGCCCAGCATGAGTACGACGAAGAGATCATCGGCACGACGCTGGAGCAGGACATGTGCGTGCTgctgggcggcggcgcggcgctggcggACGTGCGGCTGCGCGTGGGCGGCGCCAGCAGGCCCGCACACCGCTCCGTGCTGGCCGCGCGCGCCGCATACTTCGAGGCCATGTTCCGCTCCTTCTCGCCGCACGACAACGTCGTCAATATACAAATCTGCGACACGGTGCCCTCAGAGGAGGCGTTCGACTCGTTGCTACGGTATATCTACTACGGCGACACCAACATGCCGACAGAAGACTCGCTGTATCTGTTCCAAGCGCCGATATATTACGGGTTCACAAACAATCGTCTGCAAGTGTTCTGCAAGCACAACTTGCAGAGCAACGTGTCGCCGGAGAATGTTCTAGCAATCCTGCAAGCAGCCGACCGCATGCGAGCGACAGACATCAAGGAGTACGCGCTCAAGATGATTGTACACCACTTCGGCATTGTGGCGCGACAGGACGCTATCAAGAACTTGGCGCAACCCCTCCTCGTTGACATCATATGGGCACTAGCCGAGGAGCCCCACTTCGACTCGCCGCTCCCAGTCCAGCCGAGGTCTCTACCCTCGTCATCATCAGCCGACACCCTCACAGATGACCCGGAGTATGCTCGACATAGGTGCGGGAAGTCGTAG
- Protein Sequence
- MQNLGKMITEQLRNPNELDISLRMEFGPFETVHKWKRMSECYEFVGARRSKHTAVAYKDALYVFGGDNGKSMLNDLIRFDIREKSWTKTGCMGVPPAPRYHHSAVVHRSSMFVFGGYTGDILANSNLTNKNDLFEYKFPSAQWVQWKFTGQEPVPRSAHGAAVYDDKLWIFAGYDGNARLNDMWTINLLGENHQWERIEQKGQCPPTCCNFPVAVARGKMFVFSGQSGAKITNALFQFDFETHTWSRVCTEHLLRSAGGAPARRYGHVMVAHRAQLYVFGGAADNTLPNDLHCYDLDTQIWSVVQPPTDSQIPSGRLFHAGAVVGDALYIFGGTVDNNVRSGELFRFQLSNYPRCTLHDDFGRILKSHQFCDVQILVGPEKTPILAHQAILAARSQFLRTKIKEARDELTKRIAAGEEEASEISYKTPPQLSILLPEATPEAFNMVLNYIYTDRIDPTEKDEDPASPATVLLVLSVLRLALRLGVPRLRGLCARFLRANLCLANVLQALHAAHHAQLHCIKEYCLRFVVKDYNFTPIVMSKEFEEMEQSLMVEVIRRRQQPPPKPANAAAQHEYDEEIIGTTLEQDMCVLLGGGAALADVRLRVGGASRPAHRSVLAARAAYFEAMFRSFSPHDNVVNIQICDTVPSEEAFDSLLRYIYYGDTNMPTEDSLYLFQAPIYYGFTNNRLQVFCKHNLQSNVSPENVLAILQAADRMRATDIKEYALKMIVHHFGIVARQDAIKNLAQPLLVDIIWALAEEPHFDSPLPVQPRSLPSSSSADTLTDDPEYARHRCGKS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00449289;
- 90% Identity
- iTF_01260233;
- 80% Identity
- -