Pumb024746.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Pyrrhia umbra
Gene Symbol
PBRM1
Assembly
GCA_963891755.1
Location
OY982940.1:4248683-4281594[-]

Transcription Factor Domain

TF Family
HMG
Domain
HMG_box domain
PFAM
PF00505
TF Group
Other Alpha-Helix Group
Description
High mobility group (HMG) box domains are involved in binding DNA, and may be involved in protein-protein interactions as well. The structure of the HMG-box domain consists of three helices in an irregular array. HMG-box domains are found in one or more copies in HMG-box proteins, which form a large, diverse family involved in the regulation of DNA-dependent processes such as transcription, replication, and strand repair, all of which require the bending and unwinding of chromatin. Many of these proteins are regulators of gene expression. HMG-box proteins are found in a variety of eukaryotic organisms, and can be broadly divided into two groups, based on sequence-dependent and sequence-independent DNA recognition; the former usually contain one HMG-box motif, while the latter can contain multiple HMG-box motifs. HMG-box domains can be found in single or multiple copies in the following protein classes: HMG1 and HMG2 non-histone components of chromatin; SRY (sex determining region Y protein) involved in differential gonadogenesis; the SOX family of transcription factors [1]; sequence-specific LEF1 (lymphoid enhancer binding factor 1) and TCF-1 (T-cell factor 1) involved in regulation of organogenesis and thymocyte differentiation [2]; structure-specific recognition protein SSRP involved in transcription and replication; MTF1 mitochondrial transcription factor; nucleolar transcription factors UBF 1/2 (upstream binding factor) involved in transcription by RNA polymerase I; Abf2 yeast ARS-binding factor [3]; yeast transcription factors lxr1, Rox1, Nhp6b and Spp41; mating type proteins (MAT) involved in the sexual reproduction of fungi [4]; and the YABBY plant-specific transcription factors.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 2.7e-14 2.7e-11 44.6 0.0 6 60 1373 1427 1369 1434 0.92

Sequence Information

Coding Sequence
ATGAGCAAAAGACGCCGTGCATCATCCGGGGCTTCGCGTGGTGCTGACTTGGATGATAGTGACGATGGCATCGAGTTGAGTAACCCTGGCCCACCGCCATCTACTCGGAAGAGGAAGAAGCTAGACCCCAGTGAAATCTGTCAGCAACTGTATGACACGATCAGGTCATACAAGAAGGAAGATGGCACTCTACTGTGTGACTCCTTCATCAGGGCTCCGAAGAGACGCCAGGAGCCGCAGTACTATGAAGTTGTCTCACAACCTATAGATCTTTTGAGAGTGCAGCAAAAGTTAAAAACTGATACATATGAGGACATTGAGGAGTTATCAGCCGATATTGAGCTCTTGGTGAATAATGCCAAAGCATTCTACAAGCCTGATACTGTGGAGTACCGGGATGCCATTGATTTGTGGAAGCTCTACCTCCAGACTAAACAGGCCCTTGAAAATGGTGAAGACATCAAGATGCCGAAACTGTCTCGCAATGGTTCATCAAGCAGAAGATCTGATGTAGCCGAGGACCTGTCGGAAACATCAACCAATAATGAAGAGGATAATGTTTTTGAAGAATTGTTCAATGctGTAATGACTGCAAACAGTGATGGCCGTCCCCTATTCCCGGTGTTCCAATTCTTGCCATCAAAACGCCGCTACCCAGAGTACTACAACGTCATAGACTCCCCAATAGACTTGAAGACCATAGCTCAGAAGATCCAGGGCGGAGAGTACACCAATGTATCAGAGCTAGAGAGAGATCTACTGCTGATGGTTAGAAATGCTTGCCATTTCAACGAGCCTGGCAGCCAGATTTATAAGGATGCTAAGACTTTGAAGAAGGTTATACAAATGCGCAAACAGGAGATCGACCAGCACGGCCGGAGCGGTCCGGCGAAGACTTCCGAACGTATCCGAAGCAAGCGCACGTCGCGTGTcgggcctgtgcccaacagtaaGGCGCTGGCCATCATGGAGCCGCCAGGATCTGATACTGAGCCTGATGTTAAGCATTCCGAAGACAGCGGCGACAGCGACGAAGAGAAGAATGAAAACGAGGATTCACCGCAATGGAAACTGCTGGAAACCATCAAAAACCATTTAGGACCAAACGGACCTATGTCAGAACCTTTTTGGAAGCTCCCATCTCGTCGGGCTTACCCTGATTACTACAAGGAGATCAAAAACCCGGTATCCCTGAACCAGATCAAGAATAAAATAAGACGGGGCAGCTATGGGACGCTGTCAGAAGTAGCGGGtgacatgaacattatgttcGAAAACGCGAAACAATACAATGTACCCTCTTCTAGATTGTACAAGGATGCTGTGAAGTTGCAGAGAATAATGCAGCAACGCGTTCAAGAGCTACTGGACATCGTACAGAGTTCGTCAAGCGATGACGAAAGTCTGTCATCGGTGAAGAACCAGACTCAAGTGCAAACGGCGAGACCAAGAGGTCGTCCGCGCCTTAACCCCGCACCTGCCGCGACTCCTACTCCTACGAGCACTCCTATCAAGTCCAATCTCCCTCTTAAAAAGAAGCTGCATTACATATCGAAGCAGCTAGTGGAGTTCACATGCTCGGACGGGAGACAGCCCATGTTGTTGTTCATGGAGAAGCCAAGCAAGAAGCTGTATCCTGAGTATTATAATGTGATCGATAAGCCTATTGATATGATCACTATTGAAGCTAATATTAAGAACGACCGCTACAACTCAATAGATGAAATGGTATCGGACTTCCGTCTGATGTTCTCAAACTGCCGCCAGTTCAACGAAGAAGGCTCCATGATATACGAGGACGCGAACCTTCTAGAACGAGTCATGAACGAGAAACTGAAGGAAGTGAACAACAGCAGCAGCTTCGAGAGGAAAACTCCTTTGAAAACTTTCAAGGCGGCTCCCAAGGCGAGGCAGCTGTCGCCTTTTGAACAGAAGTTGAGGACTTTGTATGATGCTATCAGAGATTATCGCGATCCTAAAGCGAACCGCCAACTTGCCCTGATCTTCATgaaactccccagcaaaatCGAATACCCTGACTACTATGAGTTAATCAAGAACCCCATAGACATGGAGAAGATAGCCCATAAACTAAAGAACAATGTGTACAGCTCTGTGAACGAGCTCGCGTCCGACTTCATACTGATGTTCGATAACGCCTGCAAGTACAACGAGCCTGACTCGCAGATCTATAAGGATGCGTTAATTCTGCATCGGGTTTGCCTGCAAACTAAACAGCTGTTGAGGGAGGATGATGATGCCGTACCGGATGTACCGGCGGCGGTTCAAGAGCTGCTCCTCAATCTTTTCACCAGCGTCTACAACCATCAGGATGAAGAGGGCAGGTGCTACTCAGACAGCATGGCCGAGCTGGCCGAGCACGACGAGGCGGCTAACGGCGAGAAAGTTCGCGCGATCTCACTCGACTTGGTCAAGCGCAGACTGGACAAGGGCTTGTACAAGAGGCTCGATCACTTCCAGCAAGATATGTTCGCGGTTTTTGAAAGAGCCCGCCGCCTCTCACGCACCGACAGCCAGATCTTCGAAGACTCTGTGGAGCTGCAGTCGTACTACATCGACCAACGCGACCAGCTGTGCCGCGGCACCCTGCAGTCTCCCGCCCTATCCTTCACCAGAGACACGATGGCGACGAGTGTGGAGCTGGTTAAGCAGTGCAAGCTGTTGCAAGAAAATGAGGATGAGGATGAGACGAGATCTAGCACTGACGACTCGATGCCATCGGGCGGCGCTCCCCTGCAGCAGACGGCGTACAGTAAGGGGGACTTCGTGTACATACAGCCCGACAAGGGGAACAAGGAGCCGCCCATAGTGCAGGTCGAGCGAGTCTGGACCAACAACGAGGGCGTGCACTGCATGTACTGCACTGCTTACTACAGGCCGCAGGAGACGTACCACGTGCGCACGCGCAAGTTCCTGCAGCAGGAGGTGTTCAAGACGGAGTCGCGCCGCGTCGTGCCGCTCGACCAGGTCGTGGGCCACTGCTACGTCATGAACGTCAAGGAGTACTTCAAGTTTAGGCCTGAAGGTTTTGCCGACAAGGATGTTTACGTGTGCGAGAGCCGCTACAACACCAAACTGCGCTGGTTCAAGAAGATCAAAGCGTGGGAGGGCGCTGAAAAAGAGGCCACGCTCATTCCTAGAGAGATACCTCTGGAGCCGAACCGAACCGTGTCGGTGTTCCGTGAACGCGTGGAGAAGCACAAGGACGAGCTAGCAGAACTCGAAGTGCTGGAGAATGTACACGAGAAGGAGAGACCtGACGTGGTGATGTACAACCCGCTGGGCACGGACGACGAGAACACCTACTACGAGCAGTACAACACGGTGTGCTCGGGCGTCATCAAGACCGGCGACTACGTGTACGTGGTCACGGACGGCGGCAAGCAGATGATCGCGCAGGTCGACACCATATGGGAGACTGGCGAcAACAAATGCTACTTCCGCGGGCCATTCCTCATCTTCCCGTCAGAGGTCGCGAACATAATAAACAAGCCTTTTTACAAGCAAGAAGTGCTTCTGACGACGATGCACGACACTAGCCCACTTGTGGGCATCGTGGGCAAGTGCTCGGTGTTGGACTATGATGATTATCTTAAGTGTCGTCCGACGGAGATAGCAGAGAACGACATATACGTTTGCGAGTCTGTGTACGACGAGTCCAACCGCGTAGCTCGCAAACTGAAGGCGGGACTGCGCAAGTTTGAACATACCAAGGATGTCACCATTGATGAGATCTATTTCTTCCCGAAGCCGCTGGGCCCGCCGGCGCTGGCCACGGCGCAGGAGGTGCAGTCCACGTCGACCGCCTTCACACAGAAGCAGTTCAACCCTCATGGGAACTCCATGGACTCTATGGACAGCAAGCCGCAGTTCACGAACCTGATCAACACCACCATAGGCAGTCAGGACGTGGAGATGATCTTGGAGAATTCTCTCGACGATTCTTCACTCGCTTCCCCAGCTACGCCGCTGTCAATAGGTGGCAACAGCAATCCATACAACCCGTCGATGACGGCGACTCCCACCCAGGAGCGGTCCAGCACCGCCACGCCGGCCAGCAGCAAGAAGAAGAAGGACAACAAGCAGAAGATCGTCACCGGCTACATCCTCTACTCCAGCGAGGTGCGGAGGGCCATCGTGGCCAACAACCCTGAGTCCACCTTCGGCGAGATCTCGCGGATTGTGGGCAACGAGTGGCGCTCCCTCCCGGCCTCCACCAAGCAGAGTTGGGAGGAAAGGGCGGCCCGCTGCAACGAGGAGACCTCTGCCAAACTGGCCGAGGAGATGCGGGAGCTCGCTCAGCACACGCCAATGGAGACGACGTACGAATGCGCGTGGGACACGTGCGACTATCAGTTCGAAGACCTGTCCGACTGTATGGAGCATTGCATCGGCGATGGAGGTAACATGATCGGTACATATATCGAGACCAAGAAACCCAAGCTAGAACCGGGGCACGTGCAGCAGCACTaccgcggcgcggcgagcgagTACCCGTGCGTGTGGCGCAGCTGCGCGCGCGTGCGCAAGGGGCAGGCGCCCTTCCCCAACCTGCCGCGTCTACTGCGCCACGTGCGCGACCTGCACGTCAACAAGGGCAACGGCAGGCTCATGGCCGTGCACGAGCGCTCCAGGAACTTCGTACCCTCGTCGAAGAAGCCTGCTAAACAGATAACTTCTAACGTGCGCAGTGGAGTGATGTCGCCAGGCGCATCTCTGTCGGGAATGTCGCCGCTGGCCCGCAACACGCCGTCCCCGGGCGCGGGCGAGGGCTCGGCCACGCTGTCGGTGGCGCCGCCCGCGCTCGGCTCCCGGCCGGCGCTCGACCCCATCTTCGTGGCCGCGCCGCCTCGCGCCCAGAGACTCACGCATTCAGAGGCTTATATCAGATACATTGAAGGTTTACATTCAGAACAGAAGTACATAACACCATGGGAGAAGTCCTTAACTCCAATGCCGATCAACCCAGACCCCGCTCAGTTCAACATGCACAAAGTCCCAGCACACTGGATGACCGAGGAAGCCATCAACGGCTACTTGGCACAGGACAAGAGTCTCTCGGAGACTGACATCCAAAAAATGGACCAGAATTCTAAAATTCTAAAAGGCCTTTGCTCTTTAAGAGATTTTATGATGAAGGATGCTTTGTATCTTTCTAAGGTGGTGTATGGTAATAACCTTTGA
Protein Sequence
MSKRRRASSGASRGADLDDSDDGIELSNPGPPPSTRKRKKLDPSEICQQLYDTIRSYKKEDGTLLCDSFIRAPKRRQEPQYYEVVSQPIDLLRVQQKLKTDTYEDIEELSADIELLVNNAKAFYKPDTVEYRDAIDLWKLYLQTKQALENGEDIKMPKLSRNGSSSRRSDVAEDLSETSTNNEEDNVFEELFNAVMTANSDGRPLFPVFQFLPSKRRYPEYYNVIDSPIDLKTIAQKIQGGEYTNVSELERDLLLMVRNACHFNEPGSQIYKDAKTLKKVIQMRKQEIDQHGRSGPAKTSERIRSKRTSRVGPVPNSKALAIMEPPGSDTEPDVKHSEDSGDSDEEKNENEDSPQWKLLETIKNHLGPNGPMSEPFWKLPSRRAYPDYYKEIKNPVSLNQIKNKIRRGSYGTLSEVAGDMNIMFENAKQYNVPSSRLYKDAVKLQRIMQQRVQELLDIVQSSSSDDESLSSVKNQTQVQTARPRGRPRLNPAPAATPTPTSTPIKSNLPLKKKLHYISKQLVEFTCSDGRQPMLLFMEKPSKKLYPEYYNVIDKPIDMITIEANIKNDRYNSIDEMVSDFRLMFSNCRQFNEEGSMIYEDANLLERVMNEKLKEVNNSSSFERKTPLKTFKAAPKARQLSPFEQKLRTLYDAIRDYRDPKANRQLALIFMKLPSKIEYPDYYELIKNPIDMEKIAHKLKNNVYSSVNELASDFILMFDNACKYNEPDSQIYKDALILHRVCLQTKQLLREDDDAVPDVPAAVQELLLNLFTSVYNHQDEEGRCYSDSMAELAEHDEAANGEKVRAISLDLVKRRLDKGLYKRLDHFQQDMFAVFERARRLSRTDSQIFEDSVELQSYYIDQRDQLCRGTLQSPALSFTRDTMATSVELVKQCKLLQENEDEDETRSSTDDSMPSGGAPLQQTAYSKGDFVYIQPDKGNKEPPIVQVERVWTNNEGVHCMYCTAYYRPQETYHVRTRKFLQQEVFKTESRRVVPLDQVVGHCYVMNVKEYFKFRPEGFADKDVYVCESRYNTKLRWFKKIKAWEGAEKEATLIPREIPLEPNRTVSVFRERVEKHKDELAELEVLENVHEKERPDVVMYNPLGTDDENTYYEQYNTVCSGVIKTGDYVYVVTDGGKQMIAQVDTIWETGDNKCYFRGPFLIFPSEVANIINKPFYKQEVLLTTMHDTSPLVGIVGKCSVLDYDDYLKCRPTEIAENDIYVCESVYDESNRVARKLKAGLRKFEHTKDVTIDEIYFFPKPLGPPALATAQEVQSTSTAFTQKQFNPHGNSMDSMDSKPQFTNLINTTIGSQDVEMILENSLDDSSLASPATPLSIGGNSNPYNPSMTATPTQERSSTATPASSKKKKDNKQKIVTGYILYSSEVRRAIVANNPESTFGEISRIVGNEWRSLPASTKQSWEERAARCNEETSAKLAEEMRELAQHTPMETTYECAWDTCDYQFEDLSDCMEHCIGDGGNMIGTYIETKKPKLEPGHVQQHYRGAASEYPCVWRSCARVRKGQAPFPNLPRLLRHVRDLHVNKGNGRLMAVHERSRNFVPSSKKPAKQITSNVRSGVMSPGASLSGMSPLARNTPSPGAGEGSATLSVAPPALGSRPALDPIFVAAPPRAQRLTHSEAYIRYIEGLHSEQKYITPWEKSLTPMPINPDPAQFNMHKVPAHWMTEEAINGYLAQDKSLSETDIQKMDQNSKILKGLCSLRDFMMKDALYLSKVVYGNNL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00120513; iTF_00960929; iTF_00007089; iTF_00075542; iTF_01125466; iTF_01281341; iTF_00155298; iTF_01134792; iTF_01135757; iTF_00156244; iTF_00462391; iTF_00342200; iTF_00180482; iTF_00275266; iTF_00178159; iTF_00026851; iTF_00249699; iTF_00446147; iTF_00960163; iTF_00959402; iTF_00461561; iTF_01033735; iTF_00421362; iTF_01034588; iTF_01333827; iTF_01494307; iTF_01495045; iTF_01495775; iTF_00390372; iTF_00895943; iTF_00913609; iTF_01209272; iTF_00407588; iTF_00406754; iTF_01443849; iTF_01316356; iTF_00112498; iTF_01528292; iTF_01506341; iTF_01507217; iTF_01508064; iTF_00125126; iTF_00273606; iTF_00809142; iTF_00810072; iTF_00274430; iTF_01441094; iTF_01509606; iTF_01151207; iTF_00468174; iTF_00467410; iTF_01332711; iTF_00039816; iTF_00042635; iTF_00041777; iTF_00840296; iTF_00896808; iTF_00197363; iTF_00970408; iTF_00971372; iTF_01119336; iTF_01118315; iTF_01388469; iTF_01387599; iTF_01386706; iTF_01230591; iTF_01441096; iTF_00953513; iTF_00649098; iTF_00650010; iTF_00806731; iTF_01502091; iTF_00071436; iTF_00736620; iTF_00008012; iTF_00642317; iTF_00318094; iTF_01317294; iTF_01501117; iTF_01564654; iTF_00074511; iTF_00119599; iTF_00622833; iTF_01439939; iTF_00667492; iTF_01094919; iTF_01526023; iTF_00906156; iTF_00907885; iTF_00924685; iTF_00124274; iTF_00123379; iTF_00036726; iTF_01094042; iTF_01179490; iTF_00683363; iTF_00341319; iTF_00784396; iTF_01342220; iTF_00049905; iTF_01062804; iTF_01064667; iTF_00038776; iTF_00785208; iTF_00001177; iTF_00783484; iTF_00772881; iTF_00931409; iTF_00935729; iTF_01533937; iTF_00827954; iTF_01115698; iTF_01147378; iTF_01438930; iTF_00206995; iTF_00666536; iTF_00825736; iTF_00033807; iTF_00926607; iTF_00032912; iTF_00143069; iTF_01193587; iTF_00449108; iTF_00689396; iTF_00706964; iTF_00723956; iTF_00375222; iTF_00374123; iTF_00441494; iTF_00823043; iTF_01360617; iTF_00823898; iTF_01197727; iTF_01090774; iTF_01401295; iTF_00208885; iTF_00207916; iTF_01144534; iTF_01149590; iTF_01140915; iTF_01358870; iTF_00018167; iTF_00774487; iTF_00781827; iTF_00457230; iTF_00782639; iTF_00775250; iTF_00247189; iTF_00780249; iTF_00159838; iTF_00458048; iTF_00212463; iTF_00621231; iTF_00248080; iTF_00778003; iTF_01181887; iTF_00925719; iTF_01487703; iTF_01487702; iTF_00010072; iTF_00009027; iTF_01463253; iTF_01085240; iTF_00771929; iTF_01076505; iTF_01331577; iTF_00146426; iTF_00720294; iTF_00011990; iTF_00795706; iTF_00824744; iTF_00887401; iTF_01082441; iTF_01180314; iTF_01361626; iTF_01363111; iTF_00017339; iTF_00187163; iTF_01312227; iTF_00787654; iTF_01429939; iTF_00290710; iTF_00428126; iTF_00820088; iTF_00819166; iTF_00726363; iTF_00144572; iTF_01178563; iTF_00758172; iTF_00195165; iTF_00282397; iTF_01538749; iTF_00781022; iTF_00851806; iTF_00957950; iTF_01173278; iTF_00445183; iTF_01464159; iTF_01527231; iTF_00357504; iTF_00358562; iTF_00364928; iTF_01437984;
90% Identity
iTF_00928706;
80% Identity
-