Pcon012164.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Ptychoptera contaminata
Gene Symbol
ZFX
Assembly
GCA_963942525.1
Location
OZ012639.1:5182444-5185372[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 3.2e-06 0.00021 21.5 1.8 2 23 200 221 199 221 0.97
2 16 0.00023 0.015 15.6 0.8 1 20 237 256 237 258 0.93
3 16 0.17 11 6.6 1.4 2 23 268 290 268 290 0.95
4 16 0.00032 0.021 15.2 2.8 1 23 296 318 296 318 0.97
5 16 2.2e-06 0.00014 22.0 1.3 1 23 324 347 324 347 0.97
6 16 0.069 4.6 7.8 4.8 1 23 352 374 352 374 0.97
7 16 0.006 0.39 11.2 9.9 1 23 380 402 380 402 0.99
8 16 1.4e-05 0.00094 19.4 2.7 1 23 408 430 408 430 0.96
9 16 8.4e-07 5.5e-05 23.3 0.6 1 23 436 458 436 458 0.98
10 16 1.7e-08 1.1e-06 28.6 2.0 1 23 464 486 464 486 0.99
11 16 0.00019 0.012 15.9 2.1 1 23 492 515 492 515 0.96
12 16 1.2e-06 7.9e-05 22.8 0.3 1 23 542 564 542 564 0.99
13 16 5.9e-05 0.0039 17.5 1.9 3 23 572 593 570 593 0.93
14 16 9e-06 0.00059 20.1 2.1 1 23 599 621 599 621 0.99
15 16 4.7e-05 0.0031 17.8 3.0 1 23 627 649 627 649 0.97
16 16 0.0025 0.16 12.4 2.8 1 23 655 677 655 677 0.97

Sequence Information

Coding Sequence
atggaTAAAAGCGTAGAAACATTGTATTCATTAATAGAAACATGTAGAACCTGCTTAAAAAATgccaaaaatcaaatattaattcCAATATTTGAAAAGAATTCAATTGTTGAAATTCCACCGATTGAAATGTTTGAAGAATTTTCATCgataaaaaatataATTTGTCGTGATGATGGTCTTCCACAACATATTTGTGTCGACTGCATGGCACGTTTAAATGATGCAAAAACATTTAGAATTCAATGTGAAAACTCTTAtcaattattagaaaaatattttaatacaacatttaaaagtaaaaacgttGATAACTCAGAGACACCAAATAATTCTTTTGAAGAATTTGAATTTCTTAGTCTAGAAAATATAGaatatgattataataataaagttcaagCAGAAGTAACTCCAGACAATAGTAGCATATATGATACAGAAGAAACAGTTAATGATGAGACTGAAGATGATCAATTGAATACAAGTATAATTTCCGAATCTGAAGAGAACACTGACGAGGATAACGAAGAAGACTCTAATATTAAAGATGATGAATTATCAATTAGTGCAGAATATCAAAAAAGTGACGAAATCTTACAATGCAGTCTTTgtgataaaacatataaaagagAAgCTCATTTAATAAGACACATAAGTAGACATCGAACGACAGCGATTAAACGTAAAAAGCGATCCCTTGTGCCAATGCATGTTTGTCAAAAATGTGGTAAACGCTTTACTAGATTCAAAGGATTAGAAGATCacgaaaatgaaaatcaatgtATTTCGATTgcaaatCCAAAGTGTAGATATTGTAAGgaaagttttttaaatatgtttgatttagataaacatttaaaagaaatgcATCCAATAGAAAGACCCCATATGTGTCCTATATGCAAGAAAACATTTCAAAGTGTTTCTAATCGCAATACACATTTGCAATCGCATAATaaagaAGATTCATTTAAATGTGATATTTGTGGTCAAGGCTTTAAaagtaaagtttatttaaataagcataaaaagtCTGTGCATACCGTTTCTAATCATGAATGTCCTCATTgctttttaaaatttgataataCTGTTAAATACGAATACCATTTGAAATCTCATGAtccgaataaaaaatataagtgtaaattttgtgataaatcatttttgcaGCATCATCATCTATCAAACCATGAACGTACACATACTGGCCTAAGaccatatttatgtaatatatgTGGAAAAGattttaaacaagaatgtaattttaaattacatcTGAGGATACATAGTGGTGTCAGACCATATGTATGCAATGTTTGTGGCAAAGatTTTACACAACGTGGATCATTCGTTATGCATATGAGACAACACACCGGTATAAGACCTTATCAGTGTGAACATTGTGGAAAAgatTTTGTTCAAAAGTCATCGTTGAATGTTCATCTTAGAACGCATACAGGGGAACGTCCATTCAAATGTGAATCATGTGATAAAGCTTTTGTGCAAGctcaacaattaaaatatcataaacaTTCGGCACACGGAGGACCACCTGTAAGAAAAATTCAAGAAACAACTACACCCACTGCTCCTGTACCAGTTGAAAACAGAATTTATCCATATACGTGTCCGTTATGTAATAAAGGATTTAAAATTCCCTCATCATTGTCATCACATATGAAAGTTCATACGGAAGATCGTAAACATTTATGTACACAATGTGGTAATACCTTTAAACGAGCTGAACATTTACGGATTCACATTAATGGTgttcatttaaaacaaaaaccataCTCATgcgaactTTGTCATAAAACCTTTGCACAATCAGGCGATCGAAATATTCATATGCGACGGCATAcagGTGAAAAACCGCACACATGtacttattgtaataaaagttttcgtttattaaaagCGTTACGTGCTCATTCACGTATTCATACTGGCGAGAAACCATACAGTtgtgaattttgtaaaaagaaattcatgACTTATACAGCATTAGCAAcgcATACAACAAAACATGAAGAAGGGTTAATCATTGCTGATCAACAATTAGGAATTAAAACAGAGgataaaatcaatgaaaatatatcAGAAGAGATAACAAAGTAA
Protein Sequence
MDKSVETLYSLIETCRTCLKNAKNQILIPIFEKNSIVEIPPIEMFEEFSSIKNIICRDDGLPQHICVDCMARLNDAKTFRIQCENSYQLLEKYFNTTFKSKNVDNSETPNNSFEEFEFLSLENIEYDYNNKVQAEVTPDNSSIYDTEETVNDETEDDQLNTSIISESEENTDEDNEEDSNIKDDELSISAEYQKSDEILQCSLCDKTYKREAHLIRHISRHRTTAIKRKKRSLVPMHVCQKCGKRFTRFKGLEDHENENQCISIANPKCRYCKESFLNMFDLDKHLKEMHPIERPHMCPICKKTFQSVSNRNTHLQSHNKEDSFKCDICGQGFKSKVYLNKHKKSVHTVSNHECPHCFLKFDNTVKYEYHLKSHDPNKKYKCKFCDKSFLQHHHLSNHERTHTGLRPYLCNICGKDFKQECNFKLHLRIHSGVRPYVCNVCGKDFTQRGSFVMHMRQHTGIRPYQCEHCGKDFVQKSSLNVHLRTHTGERPFKCESCDKAFVQAQQLKYHKHSAHGGPPVRKIQETTTPTAPVPVENRIYPYTCPLCNKGFKIPSSLSSHMKVHTEDRKHLCTQCGNTFKRAEHLRIHINGVHLKQKPYSCELCHKTFAQSGDRNIHMRRHTGEKPHTCTYCNKSFRLLKALRAHSRIHTGEKPYSCEFCKKKFMTYTALATHTTKHEEGLIIADQQLGIKTEDKINENISEEITK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01276400;
90% Identity
-
80% Identity
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