Palb006921.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Ptychoptera albimana
Gene Symbol
ZFX
Assembly
GCA_961205885.1
Location
OY540803.1:26889725-26892576[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 1.3e-06 7.4e-05 22.7 0.9 2 23 196 217 195 217 0.97
2 16 0.00017 0.0097 16.0 0.6 1 20 232 251 232 253 0.92
3 16 0.03 1.7 9.0 2.5 2 23 263 285 263 285 0.94
4 16 0.00032 0.018 15.2 2.8 1 23 291 313 291 313 0.97
5 16 2.2e-06 0.00012 22.0 1.3 1 23 319 342 319 342 0.97
6 16 0.37 20 5.5 5.9 1 23 347 369 347 369 0.97
7 16 0.0059 0.33 11.2 9.9 1 23 375 397 375 397 0.99
8 16 1.4e-05 0.00078 19.4 2.7 1 23 403 425 403 425 0.96
9 16 8.3e-07 4.6e-05 23.3 0.6 1 23 431 453 431 453 0.98
10 16 1.7e-08 9.3e-07 28.7 2.0 1 23 459 481 459 481 0.99
11 16 0.00024 0.014 15.6 2.8 1 23 487 510 487 510 0.96
12 16 1.2e-06 6.6e-05 22.8 0.3 1 23 537 559 537 559 0.99
13 16 5e-05 0.0028 17.7 1.8 3 23 567 588 565 588 0.93
14 16 8.9e-06 0.00049 20.1 2.1 1 23 594 616 594 616 0.99
15 16 5e-05 0.0028 17.7 2.8 1 23 622 644 622 644 0.97
16 16 0.0024 0.14 12.4 2.8 1 23 650 672 650 672 0.97

Sequence Information

Coding Sequence
atggaTAAAAGTGAAAACACATTGTATTCATTAATAGAAACTTGTAGAACCtgtttaaaaaatgataaaaatcaaacattaatACCAATATTTGAGAAGAATACAATTGTTGATATTGCACCGATTGAAATTTTTGAAGAATTTTCATcgatgaaaaataaaaTTAATCAAAATGATGGCCTTCCACAGCAAATTTGTGTTGAGTGTATGGAAcgtttaaataatgtaaaaacgtTTAGAATCCAATGTGAGAATGCGAAcgaattattagaaaaacattttaatgcaacatttaaaagtaaaaacttgAATAACTCAGATACACTTCACAATTCTTTTGAAGAATTTGAATTTCTTAGTATAGAGAATATAGAATATGATAATAAGGTTCaaacAGAAATTCCGtcagaaaataatagtatatatgATACAGAAGAAACCGTTAATGAAGAGACTGAAGATGATCAACTAAATACAAGCTTATTATCCGAATCGGAAAGAACTACGGATGAGGAAGATgacacaattaataaaactgatgATTCTTCAATTTGTgcgaaaaatcaaaaagatgaagaaattCTTCAATGTAGTATATGCGATAAAGCATATAAAAGAGAAGCTCATTTAATAAGACATATAAGTAGACATCGAACGACAGCGATTAAACGTAAAAACCGTTCATTATCAATGCATGTATGCCAAAAATGTGGAAAACGTTTCTCTCGATTAAAAGCATTAGATAATCACGAAAATGAAAACCTATGCATATCaattaaaAATCCTGAATGCCGATATTGCAAAGAAACCTATTCAAATATGTGTGAATtagataaacatttaaaagatATGCATCCTGTTGAAAGACCCCATATGTGTCCTATATGTAAAAAAACGTTTCAAAGTGTTTCAAATAGAAATACTCATTTGCAATCAcataataaagaagatTCATTTAAATGCGACATTTGTGGTCAAGGGTTTAAgagtaaagtttatttaaataagcatAAAAAGTCTGTGCACACTGTTTCAAATCATGAATGttctcattgttttttaaaatttgataATACCGTTAAGTATGAaTACCATTTGAAATCTCATGAtccgaataaaaaatataaatgtaaattttgtgataaatCCTTTTTACAACATCATCATCTATCAAATCATGAACGTACCCATACAGGACTGCGACCCTATTTATGCAATATATGTGGAAAAGattttaaacAAGAATGTAATTTTAAGTTACATCTACGGATACATAGTGGTGTTAGACCATATGTCTGCAATGTTTGTGGCaaagATTTTACACAACGAGGTTCTTTTGTAATGCATATGAGACAACACACTGGCATTAGGCCTTATCAGTGCGAACATTGTGGAAAAGattttgtacaaaaatcaTCGCTGAATGTTCATCTTAGAACGCATACGGGAGAACGGCCGTATAAATGTGAATCGTGTGATAAAGCTTTTGTGCAAGctcaacaattaaaatatcacAAACATTCTACACATGGAGGTCCACCTGTCAGAAAAATTCATGAAACGGTTACAGCAACTCCTACAATACCTCTTGAAAATAGAATATATCCATATACTTGTCCATTATGCAATAAAGGTTTTAAAATTCCGTCCTCGCTGTCATCACATATGAAAGTTCATACAGAAGATCGTAAACATTTATGTACACAATGTGGTAATTCGTTTAAACGTGCGGAACATTTACGAATTCACATTAATGGGgttcatttaaaacaaaaaccgtaCTCATGcgaactCTGCCATAAAACATTTGCTCAATCAGGTGATCGTAATATACATATGAGACGACACActgGTGAAAAACCGCATACATGTTCctattgtaataaaagttttcgaTTATTGAAAGCTTTGCGAGCACATTCACGAATACATACCGGCGAAAAACCATACAGTTGtgagttttgtaaaaaaaaattcatgacaTATACAGCACTAGCGACGCATACGACAAAACATGAAGAAGGATTAATTATCGATGATCAACAAAGAGGAATTAAAATAGAGGATAAAATCAATGTAAACATTATACCAACAGAGATTACAACAAAGTAA
Protein Sequence
MDKSENTLYSLIETCRTCLKNDKNQTLIPIFEKNTIVDIAPIEIFEEFSSMKNKINQNDGLPQQICVECMERLNNVKTFRIQCENANELLEKHFNATFKSKNLNNSDTLHNSFEEFEFLSIENIEYDNKVQTEIPSENNSIYDTEETVNEETEDDQLNTSLLSESERTTDEEDDTINKTDDSSICAKNQKDEEILQCSICDKAYKREAHLIRHISRHRTTAIKRKNRSLSMHVCQKCGKRFSRLKALDNHENENLCISIKNPECRYCKETYSNMCELDKHLKDMHPVERPHMCPICKKTFQSVSNRNTHLQSHNKEDSFKCDICGQGFKSKVYLNKHKKSVHTVSNHECSHCFLKFDNTVKYEYHLKSHDPNKKYKCKFCDKSFLQHHHLSNHERTHTGLRPYLCNICGKDFKQECNFKLHLRIHSGVRPYVCNVCGKDFTQRGSFVMHMRQHTGIRPYQCEHCGKDFVQKSSLNVHLRTHTGERPYKCESCDKAFVQAQQLKYHKHSTHGGPPVRKIHETVTATPTIPLENRIYPYTCPLCNKGFKIPSSLSSHMKVHTEDRKHLCTQCGNSFKRAEHLRIHINGVHLKQKPYSCELCHKTFAQSGDRNIHMRRHTGEKPHTCSYCNKSFRLLKALRAHSRIHTGEKPYSCEFCKKKFMTYTALATHTTKHEEGLIIDDQQRGIKIEDKINVNIIPTEITTK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01277113;
90% Identity
-
80% Identity
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