Palb006700.1
Basic Information
- Insect
- Ptychoptera albimana
- Gene Symbol
- MBD-R2
- Assembly
- GCA_961205885.1
- Location
- OY540803.1:25091362-25095703[-]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 2.7e-18 6.3e-15 54.2 0.1 4 74 384 455 381 457 0.88 2 2 0.82 1.9e+03 -1.8 0.0 37 57 480 501 478 512 0.83
Sequence Information
- Coding Sequence
- atgggTAGACGCAAATGTTGTGTTGTGGGGTGTCGCTCTTCTGCTTTGCGTATTGAGGATAGAGGTGTCACCTTTCACaaatttccattaaataatcaaatacgTACAGAATGGTTAAAAAAATGTCATATGCCAGAAAATTTCAACATAACCAAAAGTTCATTTGTATGCTCACGACATTTCAGCAAAACAGATTTTCAAGCATACAAAGGTGTcaaatatttactaaaaaatggtGTTGTACCAAGTATTTTTCAATGGTCGACATTGGAAAACAAATCTGCCAAAAATAATGCTACTGGAGGAATAAGTGATGGTCAAACTGCTGGTACTTCTGGtgTAAAAAGATCAGCAAGTGCTGAAGGTGGTAATAATTTATCAGAACCACAGAAGAAAATAAGTAGAAAAACTTCTGATTCAGCTATTTTAGTACATCCATCTCCAGAAAAAACtcccaaaaaacaaaataatgaatcatttaaaaaatcaacaagtgAAGGAATAAATTTTGCTCCAGGAACAAAGCTTGAAGCACaggattttaatgaaatttggcATTTAGCTAAGATAATTGAAGTGGACAATGATGAGCGTGaagttttaatacattttgagAAAAAGGGAGATGAAAAAACTCCAGGTATATTTAATGAATGGATTCCAATGGATAGTAGTCGTCTACGACCACAAtcttataacaataatttaaataataaatcgtcaATTCAAAAAGTAATATCACCCAAAATTATTTCTCCTAATGGTAATGGTTTCGTTGTCGGTCAAAAATGTTTTGCACGTTGGAATGATTCAAGAAAGTTCCCTGGAACAATACAAAAAGTTTTAGATaatgatatGTACGAATTCATGTTTGATGACgggtttgttaaattattaaaaggatgtcacataacaaaaattaaaaaaacagtcCGTAAAAAGCCTATTCCAACAGAAGAAATATCTCTTATAACACCAAAAAAATGTGATGTAACAACAAATGTAAATAACGTTGACATTGcagaagaagaaattattttaactcttAGTAAGCAATTACCGGAGATACCAAAAGATGGAACATGGTGTTGTCATTGGTTAAACGATACGCCATTAGGTGAGAATAGTGTGATTGATGAATATAATACTGTTATTGTAAATGATTGGCGATTACCCAATGGTTTCATAAAGCACATGTATAATCGTACGATAACgacaaatgttttaaaaaaatgggaaattatttttgtaacaccAAGTGGTCAAAAATTAAGGAATAAACAAGAGGTGAAACAatatttagataataataaagaaaaatatgataTTGATATATTTGATTTTGGGATACATAAAAGACGTGCTAAAGAGCTTGGTTACTGTAATTATACACCAGATttcaaacaaaAACCATTGAATATATCTAGAGATTTTGGTTCGCCAGCAACACAAAAGCAAATAAgtataaaacaagaaataacacCAGTGTTAAAATCAGACGATTCTTTATTAGAACGTAGCCAAGAATTGGAAGAAGGATATGTCTATGTTGGCTCTTTAAAAGtacaaataattgataatcTCTTTCGCTGTCCGCAAGAGGgttgttttaaaaactttCGAAAGGAAAATCATTTACAAATTCACATAAAGCATTATCACAAAGAAATggcaaaATTATTAGGAGTTTGTCCTAAAATGAGTGATTTAGCATATATACGAACCATGGGTCACAATATAGATGATTCCGTAGCAAAGAATCATTTTCcaaattcacaattttttgaGAAAGCGCATCAATTAGATTTACAATCACGTATACATCGTAAGTCGTTAACTTCTCCAAATAGTagcataaaaatagaaaatgttgaTAATGGCAAAATACAAGACGAATCAATTAGTGATAATGTAATTGTAAATGATAAAATCGACATTgacaatgttaaaataaaagttgagAAACCTGaagaaacaccaaaaaaaaatttacctttgTCTGAAGAatctttaaacattaaaacaacattagataaagttgatttaaaaattgaacaatTAATCAATTCTAGTGATGTTgaattagataaaaatgatttgGCGGAGGAAACTATTAAGTTAACTGAAGATAATAAACAACACATAGTGGTCACATCTACACcctgtaataaaacaaataatgatgatgaaacGGCAGATCcagaaacattaataaaatctcattctgtaaataagattaaatttaaacaacgtaatttgatgaaaaagcgtaaattaaatattaaacgttTAGGACGCCCAccatctaataaaaataaaataatagaagatacaaatgaattaattaaaaatgatcagAATAATTCATTCATGTGTAATGAAGAAACAAGAGATTCGTTTATACAATGTCCAGATAGattaaaaaaaccattaaGTGAACCATTTAACGAGAATACAAATAGTttgacaacgacaacaactaTTGAAAGAAGTTTAAgtccaaaatatataaatgaaggtggtgaaataataaagatagtCCGAATGCGACaggaagaaattattaattgtttatgtgGGTATACTGAAGAGGATGGCCTTATGATACAGTGTGAATTATGTTTATGCTGGCAACATGGTGCTTGTAATGGTATTGAAAAAGAGTGTCAAGTACCggaaaaatatgtttgttaTATTTGTCGCAATCCACAACGTGGTCGTTTATCTATGAAATATATCCACGATCAGGATTGGCTGTATGAAGgtAAACTACCAGTTGCCAATTATCATGTCATCAATCCATATTTGAATGAACGTTTTGATTTGTTAAAACAATCACATATATTAACTGGTAATTTATTGGAATTGAAAAAGTTTCTCTATAGTTTgaaggttaaaaaaaatatatgtgaaAATAAAGATCAtccaaaaatgtatttatggtCTAAAAAATGGGAATTAAGTCCACAgcgtaataatataaataatattataaaaaatgaagatgATATGACAACGCCAAAAGATGTAGCATCAGTGGCTAATGATTtggatacaaaaaataatattattattgatgatgttattaaaaataatgatgaatTAGTACAAATATTAGAAGgcaatgataataaaagtataaatgataatttcaATGATGACAATATAGCAACGACAACAATTGtaacaacagaaaatgaagattcaaaattaataaataaaattgatgcaATTGAGACAAAtgaaacagCAACTGTAGAGAACGCAGaattaaaaagcttaaatgaTGGTGTTActagttttataaaaagtgAATTAACTGATGGTGATAATGTTATTAATGAAACTTTATCAGATGATAAAATagctttaaatgaaaatgtgcCGAATATACCTCAACCAGAAGTACCAATCGATTCTCTGGAATGTCAATCACGATTGTTAGAACATATACAAAAACAGCAATCAATGGCAATGTCTAGATTACAAACAATTGAGTCACAAATAAgtgcATTGGAATCAATGGACAATATAACATCAGGCTATGTGTATGAGACAAcagaaacattaaatataaagttgaaatcaacaattaaaatgttaatcaaagatttattaactattaagaaattatcatacataaacaataatttaacaatattgAATGAGACAACAAAAGCAGAGGCATCTCCATCCTCACCACCAACAACCGCGTCATCAAAcacttttaataatcaatatactgattttataaataattcatcaacaacaatactAGGATTGTAG
- Protein Sequence
- MGRRKCCVVGCRSSALRIEDRGVTFHKFPLNNQIRTEWLKKCHMPENFNITKSSFVCSRHFSKTDFQAYKGVKYLLKNGVVPSIFQWSTLENKSAKNNATGGISDGQTAGTSGVKRSASAEGGNNLSEPQKKISRKTSDSAILVHPSPEKTPKKQNNESFKKSTSEGINFAPGTKLEAQDFNEIWHLAKIIEVDNDEREVLIHFEKKGDEKTPGIFNEWIPMDSSRLRPQSYNNNLNNKSSIQKVISPKIISPNGNGFVVGQKCFARWNDSRKFPGTIQKVLDNDMYEFMFDDGFVKLLKGCHITKIKKTVRKKPIPTEEISLITPKKCDVTTNVNNVDIAEEEIILTLSKQLPEIPKDGTWCCHWLNDTPLGENSVIDEYNTVIVNDWRLPNGFIKHMYNRTITTNVLKKWEIIFVTPSGQKLRNKQEVKQYLDNNKEKYDIDIFDFGIHKRRAKELGYCNYTPDFKQKPLNISRDFGSPATQKQISIKQEITPVLKSDDSLLERSQELEEGYVYVGSLKVQIIDNLFRCPQEGCFKNFRKENHLQIHIKHYHKEMAKLLGVCPKMSDLAYIRTMGHNIDDSVAKNHFPNSQFFEKAHQLDLQSRIHRKSLTSPNSSIKIENVDNGKIQDESISDNVIVNDKIDIDNVKIKVEKPEETPKKNLPLSEESLNIKTTLDKVDLKIEQLINSSDVELDKNDLAEETIKLTEDNKQHIVVTSTPCNKTNNDDETADPETLIKSHSVNKIKFKQRNLMKKRKLNIKRLGRPPSNKNKIIEDTNELIKNDQNNSFMCNEETRDSFIQCPDRLKKPLSEPFNENTNSLTTTTTIERSLSPKYINEGGEIIKIVRMRQEEIINCLCGYTEEDGLMIQCELCLCWQHGACNGIEKECQVPEKYVCYICRNPQRGRLSMKYIHDQDWLYEGKLPVANYHVINPYLNERFDLLKQSHILTGNLLELKKFLYSLKVKKNICENKDHPKMYLWSKKWELSPQRNNINNIIKNEDDMTTPKDVASVANDLDTKNNIIIDDVIKNNDELVQILEGNDNKSINDNFNDDNIATTTIVTTENEDSKLINKIDAIETNETATVENAELKSLNDGVTSFIKSELTDGDNVINETLSDDKIALNENVPNIPQPEVPIDSLECQSRLLEHIQKQQSMAMSRLQTIESQISALESMDNITSGYVYETTETLNIKLKSTIKMLIKDLLTIKKLSYINNNLTILNETTKAEASPSSPPTTASSNTFNNQYTDFINNSSTTILGL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01276990;
- 90% Identity
- iTF_01276300;
- 80% Identity
- iTF_01276300;