Basic Information

Insect: Pterostichus niger
Gene Symbol: E2F2
Assembly: GCA_947425015.1
Location: OX380345.1:24255807-24258575[-]

Transcription Factor Domain

TF Family: E2F
Domain: E2F_TDP domain
PFAM: PF02319
TF Group: Helix-turn-helix
Description: This family contains the transcription factor E2F and its dimerisation partners TDP1 and TDP2, which stimulate E2F-dependent transcription. E2F binds to DNA as a homodimer or as a heterodimer in association with TDP1/2, the heterodimer having increased binding efficiency. The crystal structure of an E2F4-DP2-DNA complex shows that the DNA-binding domains of the E2F and DP proteins both have a fold related to the winged-helix DNA-binding motif. Recognition of the central c/gGCGCg/c sequence of the consensus DNA-binding site is symmetric, and amino acids that contact these bases are conserved among all known E2F and DP proteins.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 7.9e-31 1.4e-26 93.5 0.1 2 65 113 176 112 176 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	7.9e-31	1.4e-26	93.5	0.1	2	65	113	176	112	176	0.98

Sequence Information

Coding Sequence: ATGCCGCGTGGTCGGCGGCCGGCGATGCTGTGCCCGGAGCCCGCGGCTAGCCCCAGGGGGCTGCGGCGATCAGTTACCACCACTCCGGACATGACAATCGTGAAGGAAGAGGACTTGACGCCGACAGTGCATCAGCACCTCATTGATCATGGTTATGGTGTAACTCCACAACATCAGATCATGCGGGAGCCCCCCACAGTGCCTACGGTCCGGGCGCCCGAGGCAGTCAAGCGTAAGCTCAACTTGGACATGGTGATTCCTATTAAAGAAGAGTTCAAGACGCCACCTCCCAAACGTGGCAGAGTGGCCGGCAGGAAACCAGAACGCACGAGATACGATACGTCATTGGGTTTGCTTACAAAGAAGTTTGTAGGCCTTCTCAAGGGTTCTTCGAACGGAGTAATAGATTTAAATCGAGCTTCTGAACAACTTGGAGTACAAAAACGCCGAATTTACGACATAACCAATGTTCTTGAAGGAATCGGTATCCTAGAAAAGAAATCAAAGAATAACATTCAATGGAAGGGTGGAAACACTGTTTATAGCAGTAATTATCAAGCTCTTTTGCAAGACATGAAGTACCTGGAAGCTAAAGAGAATCTTTTGGATTCGCTGATTAATACAGCTGAAACTAGCCTGCGAAAAGTATGTGAAGATAAAACCATGGCCTATATCACGTACCAAGATCTTCGAGACATTCACGAATACAAGGCAAAGACTGTGATGGCTATCAAGGCTCCACCTGAATCCAAGTTGCAGGTTCCAACCGACAGCTATAAAATTTCAATGAAGAGCGACAATGGTGAGATTGAAGTATACCTGTGCCCTGATGTTAACACTGCCAAACCAAAGCAACACCGTACACCTATCCCTCCATCCGACCCGCTGTTGGAGGATGTGTTGCAGCCCAGCAAGCCCAACTTCATGAGCCCGGTGCGAGCTATCCTAACTCCGCAGAAGGCTCCGCTCACCAGTGCCAGACGAAACCTTACGTTTCAGAACTGTTCTGATTCGAGTGGTAATGTCACTGCTCAGTGTAGCAGCAAAATTAAAGATCCAGTATTGCATAGTGTGGGTATGGATGGCATAGTGCCGAAGGTGGAGCCAGCGTTCAGTACTTTTTCGACCGAGCAGTCTTGCAGCAACGCACAATACAGTGATATTGCGTTAGATAAGTTCACGTTGTCTCCGATGAATGAGAGCATCAAACGCATGTTCGAAGAGCCGTCCGGGTCAGGCCAGGATACTTCAGAGACCATTAGGTTAAAGCACGCGCTTATATCAGAGAGTGATGACTTCGGACCGATGGGTAGTCGATATCCACTGACCATTGACGACCAGCATAATACACCAGGTACGTTGGACCTATGCGCGGAACCATTCCAGCTTCTGGAACCGCCGCTATCCGTGTCTGACTACAACTTCAGCTTAGACAATGGCGAGGGCCTGGCCGACCTGTTTGACTTCAACTTCTAA
Protein Sequence: MPRGRRPAMLCPEPAASPRGLRRSVTTTPDMTIVKEEDLTPTVHQHLIDHGYGVTPQHQIMREPPTVPTVRAPEAVKRKLNLDMVIPIKEEFKTPPPKRGRVAGRKPERTRYDTSLGLLTKKFVGLLKGSSNGVIDLNRASEQLGVQKRRIYDITNVLEGIGILEKKSKNNIQWKGGNTVYSSNYQALLQDMKYLEAKENLLDSLINTAETSLRKVCEDKTMAYITYQDLRDIHEYKAKTVMAIKAPPESKLQVPTDSYKISMKSDNGEIEVYLCPDVNTAKPKQHRTPIPPSDPLLEDVLQPSKPNFMSPVRAILTPQKAPLTSARRNLTFQNCSDSSGNVTAQCSSKIKDPVLHSVGMDGIVPKVEPAFSTFSTEQSCSNAQYSDIALDKFTLSPMNESIKRMFEEPSGSGQDTSETIRLKHALISESDDFGPMGSRYPLTIDDQHNTPGTLDLCAEPFQLLEPPLSVSDYNFSLDNGEGLADLFDFNF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01225451; iTF_01040644; iTF_01039018; iTF_01039914; iTF_00469421; iTF_00872847; iTF_00766197; iTF_01104060; iTF_00767901; iTF_00028509;
90% Identity: iTF_00767901;
80% Identity: -