Pgib006154.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Psococerastis gibbosa
Gene Symbol
-
Assembly
GCA_963971405.1
Location
OZ020485.1:44193236-44207741[+]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 6.5e-16 8.4e-12 45.0 0.0 7 70 1810 1871 1805 1875 0.89
2 2 1.5e-14 1.9e-10 40.7 0.1 8 70 1998 2054 1994 2058 0.92

Sequence Information

Coding Sequence
ATGGAGTCTGATCCCACTAGACCGCCATACCCGCAAGGAAGCAATGTATCCCGAGTGTCCAGTACTATGTTTAAAATCGACTATAAAAAAGAGCCAGAGCTGCCGATAAATTATGTTGAGAGGTTAGAACATGCATTTTCTCCTCGTGGTGCCcgaaaaataatttacattaatGACAACCCACTTCACTATGTTAGAAGGCCGTGCCCTAGGACATCTGATGTTGAGGGTGTCATTGATCACTACAACTTGTGTCATATCGTTTATTCAACCCCATCAATTCCTGGTGTACCCCTGGTGCAAGAAGCTGCCATTGCATTCAGTAGGCAACCTGATCAACCTGCTGCATTTGAAAACTTGGACAATTGTGTTGGAACGTCAAGGGGGCGGCCTGAAAATGACAAGTCGACTAATATTCTCCCTGGTGACGAGAATATTAACAGTCAAGTACAACATTTAACGAGGGGCACATCAATTCCTGGAGAACCTCAGGTGCCAGAACCTGCCGTTGGGCTCACTGGACAATCTGAGCAACATGATGTATATGAAAACGCGGAAAATTGTGTTGGAACGTCAAGGGGTTGGCCTAAACACAAGAAGTCGACTAACTTCCCCGTTGATGACGAGAATATTGAGAAGAGGCAtgacaaaaatgtaaaaaggaGATCATTAATTGCTGAACAACCCCTAGTGCCAGAACCGCTCACTGGACAATCTGAGCAACATGATGTATTtgagaatgtggaaaattgtgTTGGAACGTCAAGGGGTCGGCCTAAAAACAAGAAGTCGACTAACTTCCCTGTTGATGACGAGAATATTGAGAAGAGGCAtgacaaaaatgtaaaaaggaGATCATTAATTGCTGAACAACCCCTAGTGCCAGAACCGCTCACTGGACAATCTGAGCAACATGATGTGTTTgaaaacgtggaaaattgtgTTGGGCCGTCAAGGGGTCGGCgtaagaagaagacgaagtggACAGATTTCCTTGTTGATGACGAGAATGTTGACAACGGTCTGGACAAAAATGAAACCAGGAGCCGCCGCTCCAAAAAGCGCAAGTATGAGTTGATAGCATTGAATGAAATCGACGTCGAAAAGAATAGATCGCGTTCACCaaaaaaacaaagaaaagaGAAAATTTCGACAAAAGACTCGGTTGATCAGGGTGGTGTACATTACACAAGGAGGCATCGTTCATCAAAAAAGCAAAGACGTGGACAAATCGACTCTGTTGACGAAAACGAAATTGTGGTTAAGGACAGGCGTCGTTCCCCGAAGAAACTGAAGAAGGATAAAAGTTTTATTGCAATTAATCAGAAAGACAAGGCGAAGATCAAACATCGTTCCTCAAAAAAACATAGAAGTGACTCTGTTGATGAACCTGAATTAAGGACGAGAAGGCATGATTCTTCAGAGAGGCAGATGGTTGAGCAGACAAATTTCGTTGACGAAGATCCTGGTGGAAATTTGAAAGTGAACAAAACTCGGAAAAGCTCCCGCATATCTAAATACGCCGCTGCATCTGTAGATATATCTGCGTTGGTGGAGCTCACAGCGTCGAAGAAACCTCAAACGAACATTTTGCAGACACCTAAGCGTCGCGGAAGGCCTCCCCGGGCGGCAGTTGTTAAAGATTCTTCAGATCCTTATACAAGTCACAGTCATAGGCAATCTAAACGTAGAAAAAGGAGCCGCAGTCATAGATCCATGAGTCCTCCTTTTGTTGTGAATCCTGCTACTTCGACGAAGGTTGTAATAGCAAGGTCTGCCCGGGAACATGTGCCAAAACGAGCTAAAAGGGCAGttattgaaaatatcttggCTCCCTCTGCCAATTTTACAGCATTTGACGACTCAGATTCACCTGAGCCTGAAGAAATTGAATTTCAAGATACGCTAAAAAAGTATGCATTGCAATGCTTGATTGGCAAAAGACCAAACATCCAGGCTTATACTACCACCAGCGATCGAGAGAAAAGGCGAGATAAAACAAAGTCTGTGGTTAAGGGGATGGAGAGTGAAATTTCAATCGATCCTTCAACTGAAGATTTGACACACTTCGCGCCTGACAACTGTGGGAGCAATGTTggtttaaatgcctcttcagaAGTAAAATCTGTAAAAGTTTCTACTGATAATGATGCTGCTCATAACACCAACCGTCAAGATTGCATTGCCGAAATGTTGAGTGAGGTGTCAAAGTCGACAGCTCACACTTCAGTCCCACCTGGCACAGCTAGTGAAATCTCTCCTCGAAAATCGATGCGCCTAAAACGTGCTAAGAAAATTGCATCTGCAAACGTGGCGCCTGGTATTGGCGAATCCGCACAGCAACCTACATGTGATTCTCTACAAAGCCTCCTCGGTGACATAACCAAGGACTTAAATGGCGATTCTATTATTTCATTGGCTTTGGACAACGATGCCAATTTGAATAGTGGACGTGAATCTGTCTCAAAGAATGACGAAGACATCCTTTCCgtgcaaaaaaaatcaaagccTGTAGGtgacataaaaaataaagaaagggATGTTACTGTTGGAAAATTGGTACCCGTACCCGATGAGAATGTAACAAGCATTAAAGCAAATTTGCCTGAAACGGACATTGTAAAAGCTCGCGGTGGTCTACGTTTAGGACTAAGCAGGAAAGCCCACTTGCTTCGTTCAACAGTATTCAGTGACAATTTCACCAGTATTCAAACAAAAAAAGATGAAGGCACTCGGATTGTGGTAGGTGAAGCAAAACAATCTTCCAAAAAACACAGCAGTATTGCCAATCATGACGATTTGGTGAATGATATAGTTCTTCAGCTTGAGGACAGTTCATCGCTTCCACAAACTGAATCTACAGATAAAGAGTGCAATGTGTTACGTCAAGTCGTTTCAGCCAAGATAGAAAACGTCGAAACTAAGAGGAGGGGTCGCAGTAGAAAACCGGTTCTAGGCGTTCCTAGGGAACAACCACATTTGGAAAGTGTTGAGCTTTCGCAAGAACAAGTTGCAAGCATTGAGGAATCTCTTGGTAAATTGGTAGGATTGGAAACAAAGCCTTCTGAATTCGTTCATCACGCTGATATTTGTGATACTGGAATAAGAGAGGTCAACGCGGGACGGTCCCGAAGACATGCTTTTGCTAAGCTCAATGAAGATGCTTTGCTTCAGACGGAGTGCAATGCTGAGATCTCTTCTATTCCTTCGAACACAATGTGCAGAGAATTCCCAGAAGGAAGCAAAACTTACAAGTCAACTATTAACACCTTGGTGAGCATAAAGCCGCAGGCAGTGAGGACTGATGTGACTGAAGTAAAAAGAGCTACCCGCATGGGGCAAGAGAAGGAAACAGTATGTGAGGTTGTTTCGGATGAAAATGTGATTGAAAGTGATGATTTGCCCATAGCTCTGGAAGAGCAAGTTATTGATGAGGCGCCACCTGTACTGGTTGGTTTTGATTCTATAGAAATTGAAGAAGGTGACGAAATTCCCATGCCAGAAATTACTAAAGTTCTTGCAGGCGACGGCGCGGTTGAATCTCAAAGAGAGCCAGTTCGGCTTGATGAACAGATACAACAGATGGAAGTTCATATCGACGCATCAGGAGGCTATGTTCAACGTAAAAGCTCTGCTTCGAAGCACAACTTAATTAAGACTGATAAAATTTTGGGTGCTAAACCAAAAAGCATTGAAATCTCTGACGAGAAGGTACTTTCACCTATAATAGTGGAAAAAGGATCAAATCTGAAAATTAGTGATGCCGAAAAGAAGAATAATCGCTTTCTTCTCGTGTTAGTAGATAAATTGAAATCTGTAGATAAACACAAATTTGAAAGTCCATCTATGCGTTCTTCGGAAGATAGAAGTCCCCCGAAGGTACCGGAAAAGGGTTTGGTGAAACCTGAAAATATGAGCAAATACAAATTAAccaaagaaaaggaaaaagtaAGTATTACCAGTTCTAAAATTTCTAAGAAACACTCACAGGACCTTTCTAATAGCTCTCAGTCAAAAAAAATCCGTAAGGACAGGGCCGAATTAGAAGGTGTGAAGAGCTCATTGAAAGGAGAAAAACATTCTAATAGTCACACTTCCTCGAATTTACATAAGAATAGAAGAGACAAAGAAGGAAAACACTCGGACAAAGACGTTAGGCACCATAGAGATACATATGCTATCTCTAATATTGAAGTTACCAAACCGCCAAGTTCACAGCATCTTGAGAAGAAACATGCCAGTAAATCTGTAACAAAGCATGAAGGTAAGATTGATGTTAAAAAGTCACAGAATGCCATTGGCGAGAACACAACAGATTTGGTTCCAAAGGAGAAAAGGAAAGGCGGTCATGTCAAATACTCGGCAAAGAATACAGGTGATGGCAAGAAAGCTCAGGATGGAGTAGGTTCTCAACCAAGTGGGAAACCGAAAAGTGAAACGGTGTTAAACAAGTCAACCAGCGAAGGTGCTGTGCCGCAAACAAGTAATATTTCTGTGGCCAGTAATCAGACGAAGACTCCTGATATTAAAAAGTCACAGAATGCCATTGGCGAGAACACAACAGATTTGGTACCAAAGGAGAAAAGGAAAGGCGGTCATGTCAAATACTCGGCAAAGAATACAGGTGATGGCAAGAAAGCTCAGGATGGAGTAGGTTCTCAACCAAGTGGGAAACCGAAAAGTGAAACGGTGTTAAACAAGTCAACCAGCGAAGGTGCTGTGCCGCAAACAAGTAATATTTCTGTGGCCAGTAATCAGGCGAAGACTCCTGATATTAAAAAGTCACAGAATGCCATTGGCGAGAACACAACAGATTTGGTACCAAAGGAGAAAAGGAAAGGCGGTCATGTCAAATACTCTGCAAAGAATACAGGTGATGGCAAGAAAGCTCAGGATGGTGTAGGTTGTAGTGGGAAACCGAAAAGTGAAACGGTGTTAAACAAGTCAACCAGCGAAAGTGCTGTGCCCCAAACAAATAGTATTTCCTTGACAAGTAATCAGTCGAAGACTGAGCCCCCTGTAACTATagaaaaagagaagaaaaagGCTGAACTGGGCTTAGTACCGCAGAGGTTGAAGTCAATTGATGAAAAATCACTAACTCCCAAGCTTGGTGTGACAGCCAAATCACACCGTGAGTGGCCGCCTGGTTCACCCCCCAGCCCCGATAAAAAGCCAACTAGGATCGTACAGTGTGTGGACATGTTTAGTGGCCTTGCCAAAACCCCAGTGCGCAGCAAAGATAAGAAAGATTCGAAAGAGAAGCAAAAGCGGCCGCACGTTATAGTCAACTCGCTGTTCGCCCCAGATACCCCGTGGACGGCTCGTCCAGGAGCTCCTTCGCGGTCTgtaagtaatatttttattcttgCGGTTAACAGTGGCACCAGTGCAGCTGCGAGGGAGGGAGAGCAGACGGCTAAAACTCATAAACCGCGCCTTCAACCCGGATGGAAAAGAGTAGTAGGGACGCGGTGTAGCGGCGCTACCCAAGGGAAGCGATATGTTGTTTTCTACAGTCCTAATGGAAAGCGCCTGGCCTCAAAACGACAGCTACAGGAGTATTTACTGTCAAATAATCTACTACACCTTGCGGAAAGTTTTAGCTTTAGTATTTTAGAAGATggctcaaaaataaaattaaactcacCAACACGGAGCAAACCAAATCCGAAAGAAAAAAATGATTCACATAGCCCATTGGGAAAACGATGGTCGCTGGGTTCTACTAGTAACAACACTGCTGGGTCTATTGCAACGAAAATCGATGACGTCAGAAAAGGGGAATGGAAAAAGCAAACATCACTGAAGAAACATGATCTCTCTCCATTGAAAGGGCAAGCGGGCTTGGCCTCTCCAACCAAATCATCCAAAGCTTCCGCTCAGTCTCCAAGCAAGCCTTCTACTGCCAATACCAAAAATTCATCAGTGAATTCACCCACTGATCTTAATCAAGCATCACTCGTACGAAAAGACGGTATTCTTTATGTGGACCCTCGCCTTCCTGAGGGGTGGTCCAGAGAAATTCGTCGTCAGCAATGCGGAAGGATTGAAGTCTACGTAGTGAGtcCTGATGGCAAGAAGTTTAGAAGAAGACACAATCTCGAACAATATCTTACACAGAATAATCAGCCCTACACTGTTGATGATTTCGATTTATCTGTTATGGGAAGGTTTTCACATAATGACACGAACCTGTTGCCATTAAAGACTAGTAAAGATAAATCAGTGAATGCGACTagtttaaaaagaaaaagatcaaaccttaaaattaaaaaaccggTGAATGTGAAATTAATGGACGGTTCGGCAAAAAAAGTAAAGATAGTCAAACCAATAATTGAGCAAGAGGAAAGAGAAAATGCTGTTATTGAAGAGACTACAGACATTGTAAAGGAAGACTCGGCTCCTATGACAAGAGAAGAAGCTTATGAATTCTACAGCAGAATTAACTGTGGTATGTCTCCAACTCTGAATGACGGCTCTGATGGGTCTCCTGTTGCGAAATGTGACGGAAGTAATCTTTCGCTCTCTCCTCTACCTAGTGTGGGCACTTTTGAAACGGTTCGGGGTCTTGTGCTGAGCGCCAATCTATTAAATGCTAGATCTGAGCGGCGGTTGTCGTTTGGCGTGAAAGGATTGAATTGCTCCATAAGCAAGGtcgaagaagcagaagaaggcATTCCTGTTGACTGGGTTAAGAGTCTCGCCAGTTGTCGCCCAGGAATGTCGCCACTTGAAATCGATGCGGCTACGAGCATTGCGGCAGCGACTGAATCGTTCATGCGAAGTTTGGCTTGTACTGCCCTCGAGAAAGGTGGCGGTACTGAACTGACTTACGGTGATCTAGCTTCCGCGGTGGCCGACACCCCGTCTCTGAAGCCGTTGTCAACTATCATCCCTCAGAAAATATCCTTCCGGCAGTTTCGACTGTCCAATAGGCCAACCAAGTATTTCTCCTTTAAAGTCTGA
Protein Sequence
MESDPTRPPYPQGSNVSRVSSTMFKIDYKKEPELPINYVERLEHAFSPRGARKIIYINDNPLHYVRRPCPRTSDVEGVIDHYNLCHIVYSTPSIPGVPLVQEAAIAFSRQPDQPAAFENLDNCVGTSRGRPENDKSTNILPGDENINSQVQHLTRGTSIPGEPQVPEPAVGLTGQSEQHDVYENAENCVGTSRGWPKHKKSTNFPVDDENIEKRHDKNVKRRSLIAEQPLVPEPLTGQSEQHDVFENVENCVGTSRGRPKNKKSTNFPVDDENIEKRHDKNVKRRSLIAEQPLVPEPLTGQSEQHDVFENVENCVGPSRGRRKKKTKWTDFLVDDENVDNGLDKNETRSRRSKKRKYELIALNEIDVEKNRSRSPKKQRKEKISTKDSVDQGGVHYTRRHRSSKKQRRGQIDSVDENEIVVKDRRRSPKKLKKDKSFIAINQKDKAKIKHRSSKKHRSDSVDEPELRTRRHDSSERQMVEQTNFVDEDPGGNLKVNKTRKSSRISKYAAASVDISALVELTASKKPQTNILQTPKRRGRPPRAAVVKDSSDPYTSHSHRQSKRRKRSRSHRSMSPPFVVNPATSTKVVIARSAREHVPKRAKRAVIENILAPSANFTAFDDSDSPEPEEIEFQDTLKKYALQCLIGKRPNIQAYTTTSDREKRRDKTKSVVKGMESEISIDPSTEDLTHFAPDNCGSNVGLNASSEVKSVKVSTDNDAAHNTNRQDCIAEMLSEVSKSTAHTSVPPGTASEISPRKSMRLKRAKKIASANVAPGIGESAQQPTCDSLQSLLGDITKDLNGDSIISLALDNDANLNSGRESVSKNDEDILSVQKKSKPVGDIKNKERDVTVGKLVPVPDENVTSIKANLPETDIVKARGGLRLGLSRKAHLLRSTVFSDNFTSIQTKKDEGTRIVVGEAKQSSKKHSSIANHDDLVNDIVLQLEDSSSLPQTESTDKECNVLRQVVSAKIENVETKRRGRSRKPVLGVPREQPHLESVELSQEQVASIEESLGKLVGLETKPSEFVHHADICDTGIREVNAGRSRRHAFAKLNEDALLQTECNAEISSIPSNTMCREFPEGSKTYKSTINTLVSIKPQAVRTDVTEVKRATRMGQEKETVCEVVSDENVIESDDLPIALEEQVIDEAPPVLVGFDSIEIEEGDEIPMPEITKVLAGDGAVESQREPVRLDEQIQQMEVHIDASGGYVQRKSSASKHNLIKTDKILGAKPKSIEISDEKVLSPIIVEKGSNLKISDAEKKNNRFLLVLVDKLKSVDKHKFESPSMRSSEDRSPPKVPEKGLVKPENMSKYKLTKEKEKVSITSSKISKKHSQDLSNSSQSKKIRKDRAELEGVKSSLKGEKHSNSHTSSNLHKNRRDKEGKHSDKDVRHHRDTYAISNIEVTKPPSSQHLEKKHASKSVTKHEGKIDVKKSQNAIGENTTDLVPKEKRKGGHVKYSAKNTGDGKKAQDGVGSQPSGKPKSETVLNKSTSEGAVPQTSNISVASNQTKTPDIKKSQNAIGENTTDLVPKEKRKGGHVKYSAKNTGDGKKAQDGVGSQPSGKPKSETVLNKSTSEGAVPQTSNISVASNQAKTPDIKKSQNAIGENTTDLVPKEKRKGGHVKYSAKNTGDGKKAQDGVGCSGKPKSETVLNKSTSESAVPQTNSISLTSNQSKTEPPVTIEKEKKKAELGLVPQRLKSIDEKSLTPKLGVTAKSHREWPPGSPPSPDKKPTRIVQCVDMFSGLAKTPVRSKDKKDSKEKQKRPHVIVNSLFAPDTPWTARPGAPSRSVSNIFILAVNSGTSAAAREGEQTAKTHKPRLQPGWKRVVGTRCSGATQGKRYVVFYSPNGKRLASKRQLQEYLLSNNLLHLAESFSFSILEDGSKIKLNSPTRSKPNPKEKNDSHSPLGKRWSLGSTSNNTAGSIATKIDDVRKGEWKKQTSLKKHDLSPLKGQAGLASPTKSSKASAQSPSKPSTANTKNSSVNSPTDLNQASLVRKDGILYVDPRLPEGWSREIRRQQCGRIEVYVVSPDGKKFRRRHNLEQYLTQNNQPYTVDDFDLSVMGRFSHNDTNLLPLKTSKDKSVNATSLKRKRSNLKIKKPVNVKLMDGSAKKVKIVKPIIEQEERENAVIEETTDIVKEDSAPMTREEAYEFYSRINCGMSPTLNDGSDGSPVAKCDGSNLSLSPLPSVGTFETVRGLVLSANLLNARSERRLSFGVKGLNCSISKVEEAEEGIPVDWVKSLASCRPGMSPLEIDAATSIAAATESFMRSLACTALEKGGGTELTYGDLASAVADTPSLKPLSTIIPQKISFRQFRLSNRPTKYFSFKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-