Basic Information

Insect: Pseudomyrmex gracilis
Gene Symbol: MBD-R2
Assembly: GCA_002006095.1
Location: NW:433299-441946[+]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 2.4e-17 6.5e-14 50.6 0.3 8 69 539 600 533 608 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	2.4e-17	6.5e-14	50.6	0.3	8	69	539	600	533	608	0.92

Sequence Information

Coding Sequence: ATGAAGCGGCGACGTATATCGCGCGTCGAGGGGAGGGTATCGTCCGCTGTAACCGCGACAGCGGCATCGGCAGCGgttgcggcggcggcggcggcgacgacgacgacagcggcggtagcggcggcggcggcgggggCGATGGGAATGGCGCGCAAATGCTGCGTGCGTAGCTGCGAGGCGGACGTGCAGGAGGCGCGCGCCAAAGGACTGCCGTTTCACAAGTTTCCCAAGGACGCCGCGTTGCGGGACAGGTGGTTGGCAAGCGGCGGATTTGAGGAGAGTTTCAAACCGACGCCGGGACAGGTCGTCTGCCATAGACATTTCAAAAGCGCCGACTACGAGACCGTTCGCGGCGGTCACAAATTCCTGCTCAAGAAGGGCAGCGTTCCCTCGGTTTTTGCGGATCATGACACTCGTTCCGAGTTATCAAAGTTGGAGCATTCTGCCTCACCATTATCGTCAGAAGCGAGAACACCTAAATCAGATAGTTGTGGCGAGACCTGTTACTCAAGACCGGAATCATCTGCGGACTCCTTAACCAGCTTGGAAGTAGCGGATAACGAATTTAAAATGACAACTCCGAAGGAAGAAATGAAAGACAAACTCTCTGAAAATTCTGACAGCAAATTGAACACGGTGGCGATGCAACTTGGTATTGTTGAGTCAGGAACAACAATGGAAACCAATACCAAAGATCTAATGTTAAAGGAAGAATTGAAGACCATTGAATTGTGTCCGAACAACAAGGAGTTTCAGAAAACGGAGGAATTAAAACCGAAAGTTTTAAATTGCGGTGGATTAGACTTTTCTCCCGGTGCCAAATTGGAAGCAAAAGACTTCAATGAAAAatgGTATTCTGCAAAAGTGGTGGAAACAGATTGGGACGAAAGAGAagttttaatacattttgacAAGTGGAGTTCAAGATTTGACGAGTGGATACCAATGGATAGTTCCAGACTTCGACCAGCGAACGACCAACTGTGGATCCTGCCGTCTTTGGAAACGGAGTATTTGGTGGGAGAAAGGATACTTGCTACATGGGCAGACGGTAGAAAATATCCAGCAAAAGTCCGTGCGATTTTGCCGAATGATAGGTATAACGTGTTGTTCGATGATGGATACGAGAAGATCATCAAGTCAtcgaaaatggaaaaaatcgCCGCAACTCCAACCAAGCAATTGAATGAAGCAGACGGATATATTGGCAGCAAGCAAGAAAGAAGAGATAAGAAAAGGAAACACACAGTTATGGAATTGTTTCATTCGAGAAAacgtacaaaatcagacaaaAGTACTGCTGATAAAATAccaaagaaagaagagactATCGTGAAAGAAAGTGAGGAAACTTATGTAGAAAACAAGATCAAAGTGGACGGCACGCTCTATGATGCTTGCTACGATCCGGGTACAGATTTATTAAGAGGCTTCGATGTGGCCAATCCTGCAAAACTTAAATCATATTCAAAGAAAAGCAAGAAAGAAACACCCAAACTTGACACAGATCTGGAAGAAGATGTCGGACCTGAATGGATCGACGGAGAACCACAAGGGATAGAGGCTTATATTGTAGACGGTAACGACGGACCACGTCGATCTATAATAGTGCCAGACAGAAGACTACCTCCTGGTTGGGAAAAGCACTTCACTCAAAGAAAAACTGGTTCGTCTGCTGGGAAGTGggacgttttatttatacataaacaGACTGGGAAAAAATTTCGATCCAGAAATGACATCAGAGTATTTATGGAGAATCAAGGACAATACGATTTTGATCCtgaaaaattcgatttttgtATACACCGCAGAAAACGGAATAATGTTCATCGCGTGAAACACGATGTTACACCAGAAGTaccaaagaaaataaaaactttattacctAAAACAAAACCACACACAGTGCCTACGTCCGAAAATATGTTACTCACTACAGTAACAAACAGTAGTATTGATAGTCCATTCAATACTTCTACTTCAACTCCTACAACTTCCGCTGATGGCGAGATGATCTATTCGGTTTTCATCGGATTATGTGGCGGACTTCGCGTGGAAATGGAAGATAATGCTTATAAGTGCCCTAAGGAAGgatgtaataaaaactttcgaaaagaaaatttattgcaaatgCATATTAAGCATTATCATCCTGAATATTCTAAGTTCCTGGGATCCACACCAAAAGTTGAAGATTTGGCCTACGCAAGAACAATTGGAGAATCCATAGAAGAtattattccaaaaaaatcGTCAACGTTCttggagaaaataaacaaattcggaaagaaaaaatctctacCGGAAAAGTCATCGCCCGGTTTGTTGCAACAATCGACATTGAACACTGTACAACCGTCATCTCCCTCGATATCAATTGCGCCGGAACTGGACGAGGAAATTGATCAGTCAGAGAAGTGCAGTGATTTGCAAAAAGAAGATATGAAAATCGAGACAATGTCTTCGATATCCAATCATAGCGTGGAAATAGATGAAGatgttgaaaagaaaagagagaataactGTGCGTTATCGCCTGGTACATTGTTTGACATGAAAGTCAAAGAGGAAAAACCGCAAGGTGGAATCAAAACATTGTTGCCTGTGAGACCACCTGGATCATCGGAGATACAGAAATCTGACAAGGTGAAATCTCTGGACGAAACACCGCACATCGAGCGTCCCAAGatgcaaaagaaaaagcaaCTTCCTGAGCATGGCATGAACTTGCCAGCTAAGGGAAAGAAACGACACGGTATATCAGATCTTGCCGATAGCTTTGGTGATCTGGACGACAGTGCTATGGACGCCGAGGGACCTACCGCGCTTATGTACAGATATAGCAGGAGAAAATCCGACTCCAAGAGTGACGAAAATAGCCAAAATAGTCAACTAAATGATTCTCGCATTGAAAAAAGTGATCCCTTAAAAGGGGATGTAACCAAAACAGATATTAATAATGATACAGAagAAAGCGAAGGAGTGATGATGATGATCAATGGCGAATTGGTCAAAGTAGAACAACTTCGGAAAgaggaaataataaattgcacTTGTGGCTATATGGAAGAAGACGGCCTAATGATACAATGTGACCTTTGTCTCTGTTGGCAACACGGTCACTGTAATGCAATTGAAAGGGAACGGGATGTTCCTGAAAAATACATTTGCTACATATGCCAACATCCGTATCGTCAAAGACTGTctaagaaatattttcacgATCAGGATTGGATTAAAGAAGGAAAATTGCCAAGTTTATCTAATCGATCACGGAATCAGTATGTAATAAATCAAAGGACTGCGACGCTGAAACGTTCCTATGATCTAGTTGCGGCACTTTTACAAATACAACGACTTCTTCATAGTCTGCGTGTAAAAATCAATGTGGCTCAaaagaaagatCATCCTAAATTATATCTGTGGGCGAAGAACTGGGAGAAGACGGATTTACCAAAAATAGACATCGAACCGGTACCCATAATGGAAATAACGAAATCAACTGGCGGCACTGACACGGGATCGGAGAATTTACGACACACCGAGATAAAAACGGAAGTCAAGTCGTTCATAAAAGACGATCAAGATGAAAAATCAATTGCTTCGGATTCGgaattaatgaaaattttggAAGAGGACAGCACACATTCTGACGAGTCCAAAAAGGAAGACTTGATGAGTTCGCAAGATAGTCATATACTTTTAGACGCGTTAACAAGCGGCAGTTCTgacgcaaaagaaaaaaataacgtgcAAGATGTTATATCAGACGTTAAAACGGAGAGCACAGATCTGTCAACCGAGAAAACCACAATCGATTCTACATCGGAGAAGCTTAACTCAGAACCGCTTAGTAACAGTATGCAACATGAGTCGAGTACAGCTGGTGTAGAAAACGAAATTTCGACGCCACTGCAACCTTTCATACCGGAGCCCGAGGCACCGATCGATCCAACTGAATGTCGAATGAGATTGTTGGAGCACATTGAACATTTTCAATGTCACATCGATTCCAAGTTGACATCAATAGAAGCACAAATTTGTgCTCTGGAGGCAATGGATACGGATGAATTCGCATCAGATCCGCAAGTTCAACCTCGTACCAAACAAACAGTTCAGATGTTACTTCGCGATTTGGTTACACTCAGAAAATTAGCGGCGTTATGCTGA
Protein Sequence: MKRRRISRVEGRVSSAVTATAASAAVAAAAAATTTTAAVAAAAAGAMGMARKCCVRSCEADVQEARAKGLPFHKFPKDAALRDRWLASGGFEESFKPTPGQVVCHRHFKSADYETVRGGHKFLLKKGSVPSVFADHDTRSELSKLEHSASPLSSEARTPKSDSCGETCYSRPESSADSLTSLEVADNEFKMTTPKEEMKDKLSENSDSKLNTVAMQLGIVESGTTMETNTKDLMLKEELKTIELCPNNKEFQKTEELKPKVLNCGGLDFSPGAKLEAKDFNEKWYSAKVVETDWDEREVLIHFDKWSSRFDEWIPMDSSRLRPANDQLWILPSLETEYLVGERILATWADGRKYPAKVRAILPNDRYNVLFDDGYEKIIKSSKMEKIAATPTKQLNEADGYIGSKQERRDKKRKHTVMELFHSRKRTKSDKSTADKIPKKEETIVKESEETYVENKIKVDGTLYDACYDPGTDLLRGFDVANPAKLKSYSKKSKKETPKLDTDLEEDVGPEWIDGEPQGIEAYIVDGNDGPRRSIIVPDRRLPPGWEKHFTQRKTGSSAGKWDVLFIHKQTGKKFRSRNDIRVFMENQGQYDFDPEKFDFCIHRRKRNNVHRVKHDVTPEVPKKIKTLLPKTKPHTVPTSENMLLTTVTNSSIDSPFNTSTSTPTTSADGEMIYSVFIGLCGGLRVEMEDNAYKCPKEGCNKNFRKENLLQMHIKHYHPEYSKFLGSTPKVEDLAYARTIGESIEDIIPKKSSTFLEKINKFGKKKSLPEKSSPGLLQQSTLNTVQPSSPSISIAPELDEEIDQSEKCSDLQKEDMKIETMSSISNHSVEIDEDVEKKRENNCALSPGTLFDMKVKEEKPQGGIKTLLPVRPPGSSEIQKSDKVKSLDETPHIERPKMQKKKQLPEHGMNLPAKGKKRHGISDLADSFGDLDDSAMDAEGPTALMYRYSRRKSDSKSDENSQNSQLNDSRIEKSDPLKGDVTKTDINNDTEESEGVMMMINGELVKVEQLRKEEIINCTCGYMEEDGLMIQCDLCLCWQHGHCNAIERERDVPEKYICYICQHPYRQRLSKKYFHDQDWIKEGKLPSLSNRSRNQYVINQRTATLKRSYDLVAALLQIQRLLHSLRVKINVAQKKDHPKLYLWAKNWEKTDLPKIDIEPVPIMEITKSTGGTDTGSENLRHTEIKTEVKSFIKDDQDEKSIASDSELMKILEEDSTHSDESKKEDLMSSQDSHILLDALTSGSSDAKEKNNVQDVISDVKTESTDLSTEKTTIDSTSEKLNSEPLSNSMQHESSTAGVENEISTPLQPFIPEPEAPIDPTECRMRLLEHIEHFQCHIDSKLTSIEAQICALEAMDTDEFASDPQVQPRTKQTVQMLLRDLVTLRKLAALC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01269057;
90% Identity: iTF_01268339;
80% Identity: iTF_01270568;