Basic Information

Insect: Pseudomyrmex flavicornis
Gene Symbol: MBD-R2
Assembly: GCA_014825475.1
Location: QVNW01001895.1:21310-28686[+]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 8.7e-17 5.1e-13 48.8 0.3 8 69 415 476 409 484 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	8.7e-17	5.1e-13	48.8	0.3	8	69	415	476	409	484	0.92

Sequence Information

Coding Sequence: ATGTGCAACGCGCCAGCTTCAAGTTTGCCGAACTGCGTCGCGTCACGCCGCATCATGCCGTCGGAGCATTCTGCTTCACCATTATCGTTGGAAGCAAGAACACCTAAATCAGATAGTTGTGGCGAGACCTGTTACTCAAGACCGGAATCATCTGCAGACTCCTTAACTAGCTTGGAAGTAGCAGATAACGAGTGTAAAATGACAACTCCAAAAGAAGAAATGAAAGACAAAGCCACTGAAAATTCTGATAGCAAATTGAACACGGTGGCGATGCAACTTGGTATTGTTGAGTCGGGACCAATAATGGAAACCAGTACCAAAGATCTAATGTTAAAGGAAGAATTGAAGACCATTGAATTGTGTCCGAACAACAAGGAGTTTCAGAAAACGGAGGAATTAAAACCGAAAGTTTTAAATTGCGGTGGATTAGATTTTTCTCCCGGTGCCAAATTGGAAGCAAAAGACTTCAATGAAAAATGGTATTCTGCAAAAGTAGTGGAAACAGATTGGGACGAAAGAGAAGTTTTAATACATTTTGACAAGTGGAGTTCAAGATTTGACGAGTGGATACCAATGGATAGTTCCAGGCTTCGACCAGCAAACGACCAACTGTGGATCCTGCCATCTTTGGAAACGGAGTTTTTGGTGGGAGAAAGGATACTTGCTACATGGGCCGACGGTAGAAAATATCCAGCAAAAGTCCGTGCAATTTTGCCAAATGACAGGTATAACGTGTTGTTCGATGATGGATACGAGAAGATCATTAAGTCATCAAAAATGGAAAAAATCACCGCAACTCCGATCAAGCAATTGAATGAAGCAGACGGATATATTGGTAGCAAACAAGAAAGAAGAGATAAGAAAAGGAAACACACAGTTATGGAATTGTTTCATTCAAGAAAACGTACAAAATCGGACAAAAGTAGTACTGATAAAATACCAAAGAAAGAAGAGACTATTGTGAAAGAAAGTGAAGAAACTTATGTAGAAAACAAGATCAAAGTGGACGGCACGCTCTATGACGCTTGCTACGATCCAGGCACCGACTTATTAAGAGGCTTTGATGTGGCTACTCCTGCAAAACTTAAATCATATTCAAAGAAAAGCAAGAAAGAAACACCCAAACTTGATACAGATTTGGAAGAAGATGTCGGTCCTGAATGGATCGACGGAGAACCACAAGGGACAGAGTCTTACATTGTAGATGGTAACGATGGACCACGTCGATCTATAATAGTGCCAGACAGAAGACTACCTCTTGGTTGGGAAAAGCATTTCACTCAAAGAAAAACTGGTTCATCTGCTGGGAAGTGGGATGTCTTATTTATACATAAACAGACTGGGAAAAAATTCAGATCCAGAAATGACATCAGAGTATTTATGGAGAATCAAGGACAATACGACTTTGATCCTGAAAAATTCGATTTTTGTATACACCGCAGAAAACGGAATAATGTTCATCGCGTGAAACACGATGTTACACCAGACGTACCAAGGAAAATAAAAACTTTACTACCTAAAACAAAACCACACGCGGTGCCTACGTCCGAAAATATGTTACTTACTACAGTGACAAACAGTAGTATTGATAGTCCGTTCAATACTTCTACTTCAACTCCTACAACCTCTGCCGACGGCGCGGTTTTCATCGGACTGTGTGGCGGACTTCGCGTGGAAATGGAGGATAATGCTTATAAATGCCCCAAGGAAGGATGTAATAAAAACTTTCGGAAAGAAAATTTATTGCAGATGCATATTAAGCATTATCATCCTGAATATTCCAAGTTCCTGGGATCTACGCCGAAAGTTGAAGATTTGGCTTACGCAAGAACAATTGGAGAATCCATAGAAGATATTATTCCAAAAAAATCGTCAACGTTCTTAGAGAAAATCAACAAATTCGGGAAGAAAAAATCTCTACCGGAAAAGGCATCGCCTGGTTTGTTGCAACAATCATTGAACACTGTACAACCGTCATCTCCCTCGATATCACTTGCGCCGGAACTGGATGAGGAAATTGATCAGTCAGAAAAGTGCAGTGATTTGCAAAAGGAAGATATGAAAATCGAGACAATGTCTTCAATATCGAATCATAGCATGGAGATAGATGAAGATATTGAAAAGAAAAGAGAAAATAACTGTGCGTTATCTCCTGGTACGTTGTTCGACATGAAAGTCAAAGAGGAAAAACCGCAAGGTGGAATTAAAACATTGTTGCCTGTGAGACCACCTGCATCATCGGAGATACAGAAATTTGACAAGGCAAAATCTCTGGATGAAACACCGCACATTGAACGTTCCAAAATGCAAAAGAGAAAGCAACTTTCTGAGCATGGCATGAACTTGCCAGCTAAGGGAAAGAAACGACACGGTATATCAGATCTTGTCGATAGCTTTGGCGATCTGGACGACAGTGCTATGGACGCCGAGGGACCTACCGCGCTTATGTACAGATATAGCAGGAGAAAATCCGACTCCAAGAGTGACGAAAATAGTCAAAATAGTCAACTAAATGATTCTCGCATTGAAAAAAGCGATCCCTTAAAAGGGGATGTAACCAAAACAGATATTAATAATGATACAGAAGAAAGCGAAGGAGTGATGATGATGATCAATGGCGAATTGGTCAAAGTAGAACAACTTCGGAAAGAAGAAATAATAAATTGTACATGTGGCTACATGGAAGAAGATGGCCTAATGATACAATGTGATCTTTGTCTCTGTTGGCAACACGGTCACTGTAATGCAATTGAAAGGGAAAGGGATGTTCCTGAAAAATACATTTGCTATATATGCCAACATCCGTATCGTCAAAGGCCGTCTAAGAAATATTTTCACGATCAAGATTGGATTAAAGAAGGAAAATTGCCAAGTTTATCTAATCGAACACGGAATCAGTATGTAATAAATCAAAGGACTGCGACGCTGAAACGTTCCTACGATCTGGTTGCGGCACTTTTACAAATACAACGACTTCTTCATAGTCTGCGTGTAAAAATCAATGTGGCTCAAAAGAAAGATCATCCCAAATTGTATCTCTGGGCGAAGAATTGGGAGAAGACGGATTTACCAAAAATAGACATCGAACCGGTACCAATAATGGAAATAACAAAATCAACTAGCGGCACTGACACGGGATCGGAGAGTGTACGACAAACTGAGATAAAAACGGAAGTCAAGTCGTTTATAAAAGACGATCAAGATGAAAAATCAATTGCTTCGGATTCGGAACTAATGAAAATTTTGGAAGAAGACAGCACACATTCTGACGAATCCAAAAAGGAAGACTTGATGAGTTCGCAAAATAGTCATATACTTTTAGACGCATTAACAAGCGGCACTTCTGACGCAAAAGAAAAGAACAATGTGCAAGATGTTACGTCAGACGTTAAAACAGAGAGTACAAATTTGTCAACCGAGAAAACCACAATCGATCCTACATCGGAGAAGCTTGACTCAGGACCGCTTAGTAACAGTATGCAACATGAGTCGAGTACAGCTAGTGTAGAAAACGAAATTTCTACACCATTGCAACCTTTCATACCAGAGCCTGAGGCACCAATCGATCCAACTGAATGTCGAATGAGATTGTTGGAGCACATTGAACATTTTCAATGTCATATCGATTCTAAGTTGACGTCAATAGAAGCACAAATTTGTGCTCTGGAGGCAATGGATCCAGATGAATTTGAGTCAGATCCACAAGTTCAACCTCGTACCAAACAAACAGTTCAGATGTTACTTCGCGATTTGGGTACACTCAGAAAATTAGCAGCATTATGCTGA
Protein Sequence: MCNAPASSLPNCVASRRIMPSEHSASPLSLEARTPKSDSCGETCYSRPESSADSLTSLEVADNECKMTTPKEEMKDKATENSDSKLNTVAMQLGIVESGPIMETSTKDLMLKEELKTIELCPNNKEFQKTEELKPKVLNCGGLDFSPGAKLEAKDFNEKWYSAKVVETDWDEREVLIHFDKWSSRFDEWIPMDSSRLRPANDQLWILPSLETEFLVGERILATWADGRKYPAKVRAILPNDRYNVLFDDGYEKIIKSSKMEKITATPIKQLNEADGYIGSKQERRDKKRKHTVMELFHSRKRTKSDKSSTDKIPKKEETIVKESEETYVENKIKVDGTLYDACYDPGTDLLRGFDVATPAKLKSYSKKSKKETPKLDTDLEEDVGPEWIDGEPQGTESYIVDGNDGPRRSIIVPDRRLPLGWEKHFTQRKTGSSAGKWDVLFIHKQTGKKFRSRNDIRVFMENQGQYDFDPEKFDFCIHRRKRNNVHRVKHDVTPDVPRKIKTLLPKTKPHAVPTSENMLLTTVTNSSIDSPFNTSTSTPTTSADGAVFIGLCGGLRVEMEDNAYKCPKEGCNKNFRKENLLQMHIKHYHPEYSKFLGSTPKVEDLAYARTIGESIEDIIPKKSSTFLEKINKFGKKKSLPEKASPGLLQQSLNTVQPSSPSISLAPELDEEIDQSEKCSDLQKEDMKIETMSSISNHSMEIDEDIEKKRENNCALSPGTLFDMKVKEEKPQGGIKTLLPVRPPASSEIQKFDKAKSLDETPHIERSKMQKRKQLSEHGMNLPAKGKKRHGISDLVDSFGDLDDSAMDAEGPTALMYRYSRRKSDSKSDENSQNSQLNDSRIEKSDPLKGDVTKTDINNDTEESEGVMMMINGELVKVEQLRKEEIINCTCGYMEEDGLMIQCDLCLCWQHGHCNAIERERDVPEKYICYICQHPYRQRPSKKYFHDQDWIKEGKLPSLSNRTRNQYVINQRTATLKRSYDLVAALLQIQRLLHSLRVKINVAQKKDHPKLYLWAKNWEKTDLPKIDIEPVPIMEITKSTSGTDTGSESVRQTEIKTEVKSFIKDDQDEKSIASDSELMKILEEDSTHSDESKKEDLMSSQNSHILLDALTSGTSDAKEKNNVQDVTSDVKTESTNLSTEKTTIDPTSEKLDSGPLSNSMQHESSTASVENEISTPLQPFIPEPEAPIDPTECRMRLLEHIEHFQCHIDSKLTSIEAQICALEAMDPDEFESDPQVQPRTKQTVQMLLRDLGTLRKLAALC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01269057;
90% Identity: iTF_01268339;
80% Identity: -