Basic Information

Gene Symbol
Trl
Assembly
GCA_014839585.1
Location
QVOB01023542.1:1057-2568[+]

Transcription Factor Domain

TF Family
zf-GAGA
Domain
zf-GAGA domain
PFAM
PF09237
TF Group
Zinc-Coordinating Group
Description
Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 1.2e-20 2.9e-16 59.7 0.0 16 49 11 44 6 47 0.94
2 2 0.58 1.4e+04 -3.3 0.1 5 13 57 65 55 67 0.66

Sequence Information

Coding Sequence
ATGGAATTCGTTCTAGGGGACGGACTGTCGAAGTCGCGCAGCCTATCCGATCAGCCGGCGTCGTGCCCACTGTGCGGCGCGATCCTGCGCCAATCGAGAAATCTTAGAAGACACTTGGAACTTCTGCATTTCGGTTTGGGCAACAACAGTAAGTCCAGCATACACGCGCGGCATCGGCGAGCACCCGGTACGGACAGAGCCGGCGATTTCGGCCTGTCGTCGCTGGCGTGCGTTCGTCCCACCGCCGCCAGAATGGACTCACACCTCGCCGTGAGGTCTTCCGAGGCTTCGGACTTTTCCATGATGACGCCTTTGTCGATCACTTCGTCCGTCAGTTCCGCGTCGAGTGTCAGTCTTCCAGGAAACCTGATGGGTCCGAGCTCGAGCCTGTTGGGTTCTGGCGATCAAAATGGTCACACGTTGCCGGGATCCACCTCGACCACGTGCAGCGCGTCCATGGTGCCGCCGGCTAACGGGATCTACTCCTCGGACGGCGGCGCAAGTATGCTGAGCTGCCTGCTGCCGTCGCTGCCCACCTTGCCGTCCTTCTCCGCGTCCCACGACGTGTTCCGACACGGCGAAATGCTGCGCGCGGGAATCGCTTATCACGATTCTTCGCGGCAGCACGCCAGACACATGCAACGCACCGACGTCACTTAA
Protein Sequence
MEFVLGDGLSKSRSLSDQPASCPLCGAILRQSRNLRRHLELLHFGLGNNSKSSIHARHRRAPGTDRAGDFGLSSLACVRPTAARMDSHLAVRSSEASDFSMMTPLSITSSVSSASSVSLPGNLMGPSSSLLGSGDQNGHTLPGSTSTTCSASMVPPANGIYSSDGGASMLSCLLPSLPTLPSFSASHDVFRHGEMLRAGIAYHDSSRQHARHMQRTDVT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00110196;
90% Identity
iTF_00729731;
80% Identity
-