Phyg039601.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Pseudolycoriella hygida
Gene Symbol
T
Assembly
GCA_029228625.1
Location
CM055406.1:74798297-74806843[+]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 4.8e-10 2.3e-06 28.8 0.0 3 71 11 71 9 74 0.83
2 3 0.61 2.9e+03 -0.4 0.0 33 47 503 517 500 522 0.84
3 3 2.4 1.2e+04 -2.4 0.0 12 30 846 863 842 867 0.76

Sequence Information

Coding Sequence
ATGAATCCGatcgaaaatgataaaaaagatACAATTCACAATCTTCGTGTGCCATTTGAACATGGTTGGACACGAGAATTGGTGTATTCATcgaataatatgaaaaatgcCGAAGTGTACTATGTGTGTCCAGCGGGAAACAGAATGCGAACTAAAAGAGAAGTGTTCCAGAACTTAGGAAATTTAAACATTTGGAACTTTTCGTTCGCAAAGCGTCCTCTCGGCTGCAATGGAGAGATCATTCGAACTGCTTCCGCGAGGGGTTGTCGGGACCTTGAAACTGCGTTTAAAATGCAAAAAGCGAGTGTGGACGTTGGAAATTCTTCTGCACAACAGTCAATCTGTTCTCTAATAACGGAAGCAACGGACAATAGCTCAGAGAACTACACACACATGGACGAAGATCAATTAAGGCAAGAAATCGCTAAAAAAGATGACCTCATAAAAAATTTGCGAATTTGCCTGCTTCGAAATGAATCAGAGATGAAAGCGCTACAGACCCAAATTAAGACTAAGCCAAATCTATCCCATGAAGAAACCTTAAAAACTATTGAACTCTTGTTTCCAATGCTgtcgaaaaatcaaattaacatCATGACAAATCAAAAGAAAAGAGTTAATTGGACCTGCGAAGAAATATCCACTGGCTTTGCCTTAAGTTTCTTTAGCAGAAGAGGCTACTGTTATCTGATTCATAAGCTACATTATCCACTCCCGTCAATCAGGACGCTACAGTTGTGGAGCCAGAAAATGACAATCGGTCCTGGAATTATAGAAGATAGTTTCGTTGTAATGGCAGCTATGCGAAGTTCATTGACTGAAGGTGAATCTCAGGTCATCTTAGCGTTCGATGAAATGAAGTGCAAAGAACGTTACGAAGTAAATAAAACACTTGATTGCGTAATGGGTCCGCATTCTCAAATGCAAGTGGCTATGGTTAGAGGTCTTTTCTACAAGTTCAAACAGCCAATTTTTGTAGACTTCGACATGAAAATGTCAGTCGAATTGTTGAATAGTCTCATCAAACGTTTGTATGCGATTAAGTTTAATGTCGTTGGTATTGTTAATGATAATGGTGGAGGGAATGTTGGCTTATGGACCAAATGCAACGTTAACTACGAGAGGCCATACATTTCTCATCCCATAACtaaagacaaaatttttatgttcTCGGATGCTCCACATCTCTTGAAGTTATTAAGAAATTGGTTTATAGATGGGGGATTGCTTTTATCAGATGGAACTGAATTGAACCAATATCGAATTCGCCAACTTTTGGAGAGCAATACAGAAATTAGTCCGTTGTATAAACTGAGTTTACATCACCTCGAAGTCAAAGGTGCAGAGCGTCAATGCGTGAGATTGGCTTCTGAATTGTTTTCCCACACTGTTGCTGAAAGCGTGAGAAGAAATTTTCCTAAAGATGCTGTTGCACACAAACTTGCCGATTTCATTGAGCTCGTCAATAACTGGTTTGACATAATGAATTCTTACACGCCAAATGGCATTGCATACAAAGCGCCCTATGGAAAGGACTTAGAAGAGCAAAATCGGGTGTTAGACGAAATGTACTGGACAATTAAAACCATGAAGTGTTTCAACAAAAAAGGAGAGTTGCAAGAATCGctgcaaatttcccaaaaaggGATACTGATGTCAATTACATCGATCAAAGGTTTGCGGAAGGAAATggaggaaaaatttaaattccgaTTTATTCTAACACATCGAACGAATCAagatttcgaagaaaattttttttctcaaattagGGGTAGAAATGGACCGATAGATCATCCATCGCCTGTTGAATGTTTGTATACTATAAAAGCCATAATTCTTGGAAAGAATCCTGGCATAGGTCGCCATTTACACTCGAATACTATTGAACAAGACCCGGAAGAATATGTGTCGGCCACATTCATGCGTCACTTGTCTCGTGATGAAAATATTGACGGAATATGTGAAAGAAATGATGAGATTGGTAACATTGAGCTCCTAGAAAACGATTCCGACGACGATATTCGAGAAAAGATAGCGAACGATATGACCGAAGATTTCCTTGCTGATTACACCAACGATATAAAAGTGCTACCAAACGATTCAAATGGATTGGAAACGTGTATACGTCTGGAGATAGAAATCATTGACGAAGCACAGACAGAGTTTTTAGATGACCTTGACCCTGAAATGGCAATCGATGAGACTGCAGCAAGGAAAGCCAGATCCACAGAAGATGGCCTTGAGTATTTAGCTGGATGGATTGCttggaaattcaagaaaaagcaTCCAGAATTTTCAAAGACAAGACGCGAAACACTTTCTAGTCACATTACCGACCACACTTACGCTAAGCGTATTGGAATTGAATCTAGCTCCTGGATAGATCGAGTGTCGTACGGAGGACTGACGAAACCGTCCAACGAAGTGATGCAGTGGGTTCGACACAAGAAAGATCCGATAAAGAAAAGTGGAATTTACATATGTGAATGTTCTTGCGGATTTACATATGTGGGTCAATCCAAGAGAGCTGTGGAAGAACGATGGAAAGAGCATCTGCGACTTATGAAAAACAACTCCGCAGAAAAATCAGCAGTAGCGACACATTTTCTAGACAACACAAGTCACGAACTTGACAAAGGAAAATTTAAACTAATCAAAAACGTTAACTACGAATATAATCTAGAAGCTTTCGAATCGTTTTACATGTACAAATTCAGAGACAAACTTATGAACGTTAAGCCACCTGAAATTGAAAGTGATTTGTTTCGGGTGATTTGTTAA
Protein Sequence
MNPIENDKKDTIHNLRVPFEHGWTRELVYSSNNMKNAEVYYVCPAGNRMRTKREVFQNLGNLNIWNFSFAKRPLGCNGEIIRTASARGCRDLETAFKMQKASVDVGNSSAQQSICSLITEATDNSSENYTHMDEDQLRQEIAKKDDLIKNLRICLLRNESEMKALQTQIKTKPNLSHEETLKTIELLFPMLSKNQINIMTNQKKRVNWTCEEISTGFALSFFSRRGYCYLIHKLHYPLPSIRTLQLWSQKMTIGPGIIEDSFVVMAAMRSSLTEGESQVILAFDEMKCKERYEVNKTLDCVMGPHSQMQVAMVRGLFYKFKQPIFVDFDMKMSVELLNSLIKRLYAIKFNVVGIVNDNGGGNVGLWTKCNVNYERPYISHPITKDKIFMFSDAPHLLKLLRNWFIDGGLLLSDGTELNQYRIRQLLESNTEISPLYKLSLHHLEVKGAERQCVRLASELFSHTVAESVRRNFPKDAVAHKLADFIELVNNWFDIMNSYTPNGIAYKAPYGKDLEEQNRVLDEMYWTIKTMKCFNKKGELQESLQISQKGILMSITSIKGLRKEMEEKFKFRFILTHRTNQDFEENFFSQIRGRNGPIDHPSPVECLYTIKAIILGKNPGIGRHLHSNTIEQDPEEYVSATFMRHLSRDENIDGICERNDEIGNIELLENDSDDDIREKIANDMTEDFLADYTNDIKVLPNDSNGLETCIRLEIEIIDEAQTEFLDDLDPEMAIDETAARKARSTEDGLEYLAGWIAWKFKKKHPEFSKTRRETLSSHITDHTYAKRIGIESSSWIDRVSYGGLTKPSNEVMQWVRHKKDPIKKSGIYICECSCGFTYVGQSKRAVEERWKEHLRLMKNNSAEKSAVATHFLDNTSHELDKGKFKLIKNVNYEYNLEAFESFYMYKFRDKLMNVKPPEIESDLFRVIC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-