Basic Information

Gene Symbol
-
Assembly
GCA_900064475.1
Location
FIZU01030052.1:77189-77801[-]

Transcription Factor Domain

TF Family
zf-GAGA
Domain
zf-GAGA domain
PFAM
PF09237
TF Group
Zinc-Coordinating Group
Description
Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 5 0.0042 20 5.8 0.0 26 47 31 52 25 55 0.89
2 5 0.0016 7.7 7.1 0.0 26 46 59 79 53 84 0.90
3 5 0.14 6.5e+02 0.9 0.0 26 44 87 105 80 110 0.84
4 5 4.6e-05 0.22 12.1 0.1 23 44 112 133 97 138 0.84
5 5 0.0051 24 5.5 0.0 21 43 138 160 133 167 0.81

Sequence Information

Coding Sequence
atgactcTTAATGAAATAAGCgacttaaattttgaacaagatgACGTCTATAAAAGAAATACgcttgaaataattcaaaatcctCAATATATTTGTGATATCTGTGGTAAAATGTATAAACATAAATCTAATTTAGAAATGCACCTTGAAATTCACAACGGAACAAGTGGTTTTACTTGTGAATTTTGTGGTAaactttttagtcaaaaaattagcctCAGAAGGCATTTACCTATTCATACTAAAATTCCTCAATTCACATGCGATATTTGTGATAAAGAGTTTATACATGAGAAGACATTCAAACGTCACATGTCGAATCACACCGGATTGAACCCTGTTAACTGCCCAGTTTGTGATGCCGGTTGCGACAGCAGTACTCATTTGAAGAGGCATATGCGTTCCCATACCAAAGAGAAACCATTCGCTTGTGATATTTGCGGAAAATGTTTCAGTCAGAAGTTTAACATGTATGCACATAAGCGGACAATTCATGAAAACATCAAGGGATCTACTAGAAATTCTTCTCAAAgatcgtaa
Protein Sequence
MTLNEISDLNFEQDDVYKRNTLEIIQNPQYICDICGKMYKHKSNLEMHLEIHNGTSGFTCEFCGKLFSQKISLRRHLPIHTKIPQFTCDICDKEFIHEKTFKRHMSNHTGLNPVNCPVCDAGCDSSTHLKRHMRSHTKEKPFACDICGKCFSQKFNMYAHKRTIHENIKGSTRNSSQRS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01262843;
90% Identity
iTF_01262843;
80% Identity
iTF_01262843;