Basic Information

Gene Symbol
HIVEP1
Assembly
GCA_017607525.1
Location
JAANIA010000305.1:16587-24774[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.0064 0.37 10.5 0.1 1 23 100 122 100 122 0.97
2 9 0.006 0.34 10.5 2.4 1 21 128 148 128 152 0.86
3 9 0.006 0.34 10.6 0.1 1 21 362 382 362 383 0.96
4 9 1.1e-06 6.3e-05 22.3 1.6 1 23 1108 1130 1108 1130 0.99
5 9 5e-06 0.00028 20.3 5.2 1 23 1136 1160 1136 1160 0.92
6 9 2.5e-06 0.00014 21.2 0.2 2 23 1843 1864 1842 1864 0.97
7 9 8.6e-05 0.0049 16.4 1.9 1 23 1870 1894 1870 1894 0.92
8 9 0.0017 0.096 12.3 3.2 1 23 1915 1939 1915 1939 0.93
9 9 1.4 81 3.1 0.6 1 19 2096 2114 2096 2119 0.92

Sequence Information

Coding Sequence
ATGACAGACCCACAGCTgaccaataataataacaacaataacaacaacaataaCAACGATGGCGAGCCAAAGTACCTacacaaaaaattcaagaagatGGCGACGACCGAAGTTGCGCCGAAAGTCGTCGAGAAGGAGGGCACGGAAAACAACGTCATTTCTGACGAGGCACCAAAACGAAAGGACGACAATAAGGACGGCAAGGAGTCATCGAAGGAACTCGGCAACAAACTCGAACCTTCGCCGGAGCCGACAGGGGGAGTCGAGCCCACCGCTGAGTCTCGAAAGAGTGGCAGCTACGCGTGTCCTTTCTGCCCGATGACGTGGACCAAGCCGAGTGTCCTTCAGAAGCACATCAGGGCGCATACAAACGAACGACCGTATCCGTGCGTGCCATGCGGAATTTCCTTCAAGACCAAATCAAATCTGTACAAGCACTGTAGGTCGCGCTCTCATGCACACAAGATGGAGAAAGGAGAGAAGGTATCTGAGGATTCCGACATAAGTCTGTCGGATAGCGCCAGTAATGGTACTGGTacaccaccgccgccgccagCTTCGGCGTCCACAACGGCAACGACGACAGTATCCACTGCTGTAGTAAAGACCGTGAAAACCGGCAAGATCTATAAGCCAAAGTTTCAAGCCCGAACAGCATTACAGTGCGTGAACAGTGACACCGAAACGTCTTCCTTATCGCCCAGTTCTTCTAACAGTTCCTGCTTGTCTTCCTCCACAAATACTTCCACTTCCAATTCTGTTAAACCTAAGGCGGAGCAGCTACAGGAGCATATCGACAAGATTATTACAGACAATCAGGCAATCGTCGATGCAGTGGATCCATGTCTGCACAAACTAATGCATCGCCAACACAGCCTAGTCGAGACAAAACAGTCATTTGAACAGCAGCCGTTAAACTTGTCTTCCGCGGAGGAGATCTTGAACAACAGAAAGCGCTGTTACAGCGATAGTTGTGCTCAGGAAGCGAAAGATGAGCTTCCGGATAGCTCAATCATCAAGGATCTTCTTTTAAAAACTCGCGGTTCTATGAACGGACCAGTACCGGAGACTGCCGTAGAAAATTTTGTCTGTCTCACTTGTAACATCCCCTATACTAGCATAGACAATTTAGAGGCTCACCGCAGATATTACTGTAAAGGTATTGACAATTCTCGAAAAGGAATCGATTATCACGCGGACTTAGAAAAACGAGATTCTGATTTCGATGTAAAATCTGCCGATTATTATAGCACCTTGCAACCGTTACCCTCGCCGGGTCCTCTACTAGGTAACACTAGACTAGTCGACGCGTACGCTCCACCTGCCAAGAAGCAAAGAACGGAAACTGTGCCGACCAGTTTAAGATCGCTAGAGGAGCTCAGCAAGTATCCGCGTCCAAACTCGCTACAGATGTTCGGTGGTGAAGTGAGGATTCTCGACTACACGGGCGAAGTAACGAAAACGATGAGGATCGAGCCACGACAGACAAATTCGCCCACGAACGAGCACGTTATCAATAGCAAGTGCATCAACTCGGAGACGGCATCGATAGTGGTGAAATCGGGACTTCATTCTGGTGGTACCATGATGCATAAACCGCCGGAAACATCGGCTAACACGTCCAATTCCTCCATATCTCTGCCCAACGCACCGAAGATATTGGCGCCCATTATACCAAACATATCAACCCCGAATATAGCGCCTACTATGTCCTGTTATGACTACTTGGAGTCGCACCTCAACCCGCTGACGAGCATCACTGCCTACAATCCGTTGACTTTGCCGCAAGCTGGTATCACAAGTATCCTCCATGGCGGAAAGGTGATACCTTATGTACCTGGTATGCCCGGACCACATACTCTGACCGGTACGCCGACTATAGACATATCTCCGAGTATAACGGCTGGCGAAGCCGGTTATAAAGTGATACCGGGCCTACCAGGCCTACACATGATACCTCAGCCACTCGACCTGGCTAGTTCAGTGAAGGTACAGCCCAGTACCGTGCCTGGTATGCCCAGTCCGTTGTCTGGACATGTTCCTTCCTTGCTAGATCAGCCTCTGGATTTGGCTAGTCCGGCGAAGGAGTCGATGAAGATCAGTTTCAAAACACCTAATGGCGATGGTCTGAAGAGCGGTTTGACCAGTCCCAAAGTTCCTAACGTCAAGGTCGAAACTTCGACAGACAAGTATCGCACGAGGATGCCGTCAACTCTCACCGGTGGAGAGACCGGCAAAGCAGAGCTCGATCGtcatatcaaaaataatacggCCGTAAAGTACAGGAGTATAGAGAGTCCGCGAGAGAGGAAGGATTTTACATATGACAAGAGTCCAAAGTTGGACAAGACTTTTAGTTATCCAAATGGCGTGGATCCCACAATTTCTTCGAACTCTTACAACAAGATGAGATACTCGCCCAAGACCATTTCGGAAAATAAGAAGAGATCATCGAATTGGGGTGTCAGTGAAGTTGATGCTGGTAGAACACTCCCAGTAGATACACACACTGCAATCTCTAAGTTAGATCTACCTGTACACGAGAACAgtcgattaaaaaatagtgTCTCTTCGGATACACGTGGATGGATTAAAGTCGCGGACGGATACGGCGCATTCAACGGCGCTAAGATAAAGGCCGACAACGCGTCATCGGTAATACTTGTAAACTTAGATTCTTCCAAGACAGAAGTGCCAACGAAAACTTCCGTAGAATTAATTGTTAAGGACAAACAACTCGAGGCCAAATCGCCGAAGAGCGGCGACGTCGTTAAAGAAACAATTAATGCTAATAAGTTCTTGAGACCCACGTCTCTACCGTTGAAACCCGGCACGTTTACGCCGAAGAGGCATCACGGGATCACGCCTACGGCGAACACGCTTCCTCTCATCAGTCCGGAGACTCCGCGACCCAAGAAGTCGTATGGACAACTATATCTAAATGGGCATGCTTACACATATCTAGGTCTTAAGTGTTCCACCAGGGTGTTTTATTGTACCTTAAATCGACCGCAGCCAATGTATGTCACACAACAGCACGGTCTGTCGATGTACTCCAATTGGAAGATATGCAAGGAGGCACCACCAGATGTGGACATGGCACACTACGACTCTCGACATAGACCTCTCAATTACACGACCGCTTGGAAGAAACAAGAGGCTATTTTAACTCACTCTTCGCAAAGACCAACCACTCCCACCAGTCCGGACAGTGGATTGGAGAGTGACATGCAGGAGAAGACGAAAAGAGTGAAGATATTTGACGGAGGTTTTGAGAGTAATGAAGATTACACCTATGTGCGCGGAAGAGGACGAGGACGTTATGTCTGCGAAGAATGTGGTATTCGTTGTAAAAAACCATCTATGTTGAAGAAACATATCAGAACACATACCGATGTTAGACCGTATACTTGCAAGCATTGTACCTTTAGTTTCAAAACAAAGGGTAATCTTACGAAACACATGAAGTCCAAAGCTCACTACAAAAAGTGTGTGGAATTGGGCGTAGTACCAGTTCCTACAACTGTCTGCGACGAAAATATCGACAAGGAGGCTATCGCGCGATTAGCTGCTGGTGGCGGTAACACGGAAGAATCTTcagaggaggaggaagaaagTGACGGAGAAGAAAGCGAGGAATCGGGCAGCGAGGAGCAAGAAGCAGCACAAAGTCTACTCAGTCTTTCACAACGTAACACGTCGAATAGATTGCCCGGCTTGTTACCGTCTGGTAGACCCACAACTTATCCATACACGCTAACTTTACCTACGACTTCCACGATGAGCATCATGTCTACTACTGCGGCTACGTCTACCATCAGTCAAAGTGTCACTACGCAAGAAACAACTTTGATCCAAAATGAATTATCGCATCGTTATTACTTCCCATCAAACCGAAATACGACGGAAGAAACGAGGATCAGTGTCATCCAATCGTCAAAGAAAGATGATTCTGACTTTGAGATCGAGGAAATCACCGAAGTCACGGAGTCACGTCATCAGCTGTCGCAACCCATGGATCTCACGACGAAGCAGACCACTCAGGTGTTGCCCTCGCCGGTCCCGCGAAGAATTAGACACGCGGACATTCTGACACCCGTTTCGGAGCCGGTCTTATTGCAGACGATAGTCCAAACGATGGAACGGCTGCCTATACAGGGTAGGGAATGGAAACCGGATGCGGAGGGCCACATGTTGCAGGCCTACCTCACGGAGAGACATGTGATGGACAGCAAAATTAAGCAACAGTATCGCGTGGGAAATACTAAGAACAATAAGCAGATACAGGAAAGAGATATTTACCTGCGTCATCAGGATCAAAATAGGTCCAGGCACATAGATTCCAACGGTATTCCGACGGTAACGTATACCGATCCTAGCAAAATGCAGCATATCGTTATGGAATCTAGGATTAAACCAATGACGAAGCATACCAGTGACGACATTAAGATGGAAATTAGGGAGAAGATTTATCAGAACAATATGGCAATGGAAAGACGAACATTCGATTACGAGGCTATTCACAAGAATAAAGAACAGACTAACCGTATGGTTTCTGATCGTGAAAATTTTGAGCTTGGTCTAACTAACGGTCCCGCTAGCACAAGACCAAGTATTGAGTATGGTCTACCTATGACCAGGAACAATAGTTCGATCGAGAGACCGAACTGTTCTATTGTACCTGTTCGCAACACATCCAGTATTGATTGTCATTCACcgaaatctttaaatatggACGTCAATAACCGATCACAATTGATGCAACATACGAACAACGACATTGACAGAAATTCTATGTTCAACGCGATGAAGATGGTGAGTGAAATAGAAAGACCTAGGGAATGCCATCCTGTTGGTCCGGAAGTAAGATCTGCTAATCACGAGATGAGAACCGCAACTAATGATATTCGAATGCAGAATCATAGTCCACGAAATCTCGATCTAAGGCCGCCTAGTAGAGAGATCAGAACGCCCGGTCAAGAGTACAGAACACAGAATCAGGAATTGAGGCTACCGAGTCAACAGGAGTACAAGATACGCGGTCAAGAAATGAGACCGCCTAGCCGTGAGTACAAACCATCGTTCGTTCACGATATGCAAGTTATTCAGGAGCTTATACCATCGGCAAACATGGAAATCCGGCAAGCAAATCCAGATAATAGACCGCCGAGCCGTGATATGAGAGCTCTCGCAGAATACAGAACGCATGCGCAAGATCCACGTGTCAATTACGAAATATTACAGCCTATACACGAACCATCCAAGTCGCAGAACGTAGACGTGAGAAGCACAACACCGCAAAAAGTACGAATTCTTTATTATGATACGAAACACACTGCAGACATAATTAAACAGAATGCATTAGATAGCATGAAACATGCAGTAGCTGGAAAGATAGTCGTCGGTGGGTCAGATTTTCAATCGCCTTCACCAAACACAGTAAACGCGAAACCGCAAGCGGAATTTCTACAACCGTCGAGTGGACCCGCGCCTAACTATGTCAGTGTCACAGAAGATGGTAGGAGTGTATGTGGGATTTGCAATAAGGTGTTCAGTAAGCCTAGTCAGTTACGGTTGCACCTCaacattcattattttgaGCGGCCATACAAATGCGAAAACTGTGCAGTTTCCTTCCGGACTAAAGGCCACTTGACGAAACATGAAAGATCCGTTTCCCATCACAATAAGgtCAGTATGACTTCTACGTTTGGTGCAGCGACTACTAGCAATCCCAGACCTTTCAAGTGTACAGATTGTAAGGTAGCATTCAGAATACATGGACATTTGGCCAAGCATCTTCGCAGCAAGATGCATATCATGAAATTAGAATGCTTGGGCAAACTGCCTTTTGGAACATATGCAGAGATGGAAAGGTCTGGCATCAACTTGAATGATATCGATACTACAGACTGTGATAATAGTCTTAATAGTCTGCAGATGTTGGCTCAAAGATTAGGCGAAAAAGATCCGGCGAAAATCGCACAGTGGGACTCGGAAACTCTACCCGGACCGGTCGTGAGTGGCAGTGAGACTTCGTCAGATGAGGGTGAGCCTATACCGCAGCACGCACTTCATGCAACATACGTGAAAGCGACAACGGACGCAGACATTTCTCGACCATATCACATGTCAATCGTCCCCGAGAAACCGAAAGCCATTAACGACGTTCGCCTCCGCAGTCCTCAGTTCAATCAGCATAGACGTGATTATTCTGTTAAAGAGCAGCGACCAATTCCGGTGGTTGTTCCGGAAGACGCAAGACCGGAAGATAGTTTACAATCGTACAAGTGCCAAGTTTGCCCCGTATCTATGCGTACTGTAAATGAGTTACAGGTACACTGTTTTGTTGAACATAATATTGAGACGGATTCTAGTACAAATATTCATGGAGATAGAAGTGCGGGTAAATGTAGGGAAAAAGAGAATActcaaaaaagaattatggACGAATCCGTAGTGAAGGAAGATCACAAAAGACAAAGGATAGAGGATACA
Protein Sequence
MTDPQLTNNNNNNNNNNNNDGEPKYLHKKFKKMATTEVAPKVVEKEGTENNVISDEAPKRKDDNKDGKESSKELGNKLEPSPEPTGGVEPTAESRKSGSYACPFCPMTWTKPSVLQKHIRAHTNERPYPCVPCGISFKTKSNLYKHCRSRSHAHKMEKGEKVSEDSDISLSDSASNGTGTPPPPPASASTTATTTVSTAVVKTVKTGKIYKPKFQARTALQCVNSDTETSSLSPSSSNSSCLSSSTNTSTSNSVKPKAEQLQEHIDKIITDNQAIVDAVDPCLHKLMHRQHSLVETKQSFEQQPLNLSSAEEILNNRKRCYSDSCAQEAKDELPDSSIIKDLLLKTRGSMNGPVPETAVENFVCLTCNIPYTSIDNLEAHRRYYCKGIDNSRKGIDYHADLEKRDSDFDVKSADYYSTLQPLPSPGPLLGNTRLVDAYAPPAKKQRTETVPTSLRSLEELSKYPRPNSLQMFGGEVRILDYTGEVTKTMRIEPRQTNSPTNEHVINSKCINSETASIVVKSGLHSGGTMMHKPPETSANTSNSSISLPNAPKILAPIIPNISTPNIAPTMSCYDYLESHLNPLTSITAYNPLTLPQAGITSILHGGKVIPYVPGMPGPHTLTGTPTIDISPSITAGEAGYKVIPGLPGLHMIPQPLDLASSVKVQPSTVPGMPSPLSGHVPSLLDQPLDLASPAKESMKISFKTPNGDGLKSGLTSPKVPNVKVETSTDKYRTRMPSTLTGGETGKAELDRHIKNNTAVKYRSIESPRERKDFTYDKSPKLDKTFSYPNGVDPTISSNSYNKMRYSPKTISENKKRSSNWGVSEVDAGRTLPVDTHTAISKLDLPVHENSRLKNSVSSDTRGWIKVADGYGAFNGAKIKADNASSVILVNLDSSKTEVPTKTSVELIVKDKQLEAKSPKSGDVVKETINANKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPKKSYGQLYLNGHAYTYLGLKCSTRVFYCTLNRPQPMYVTQQHGLSMYSNWKICKEAPPDVDMAHYDSRHRPLNYTTAWKKQEAILTHSSQRPTTPTSPDSGLESDMQEKTKRVKIFDGGFESNEDYTYVRGRGRGRYVCEECGIRCKKPSMLKKHIRTHTDVRPYTCKHCTFSFKTKGNLTKHMKSKAHYKKCVELGVVPVPTTVCDENIDKEAIARLAAGGGNTEESSEEEEESDGEESEESGSEEQEAAQSLLSLSQRNTSNRLPGLLPSGRPTTYPYTLTLPTTSTMSIMSTTAATSTISQSVTTQETTLIQNELSHRYYFPSNRNTTEETRISVIQSSKKDDSDFEIEEITEVTESRHQLSQPMDLTTKQTTQVLPSPVPRRIRHADILTPVSEPVLLQTIVQTMERLPIQGREWKPDAEGHMLQAYLTERHVMDSKIKQQYRVGNTKNNKQIQERDIYLRHQDQNRSRHIDSNGIPTVTYTDPSKMQHIVMESRIKPMTKHTSDDIKMEIREKIYQNNMAMERRTFDYEAIHKNKEQTNRMVSDRENFELGLTNGPASTRPSIEYGLPMTRNNSSIERPNCSIVPVRNTSSIDCHSPKSLNMDVNNRSQLMQHTNNDIDRNSMFNAMKMVSEIERPRECHPVGPEVRSANHEMRTATNDIRMQNHSPRNLDLRPPSREIRTPGQEYRTQNQELRLPSQQEYKIRGQEMRPPSREYKPSFVHDMQVIQELIPSANMEIRQANPDNRPPSRDMRALAEYRTHAQDPRVNYEILQPIHEPSKSQNVDVRSTTPQKVRILYYDTKHTADIIKQNALDSMKHAVAGKIVVGGSDFQSPSPNTVNAKPQAEFLQPSSGPAPNYVSVTEDGRSVCGICNKVFSKPSQLRLHLNIHYFERPYKCENCAVSFRTKGHLTKHERSVSHHNKVSMTSTFGAATTSNPRPFKCTDCKVAFRIHGHLAKHLRSKMHIMKLECLGKLPFGTYAEMERSGINLNDIDTTDCDNSLNSLQMLAQRLGEKDPAKIAQWDSETLPGPVVSGSETSSDEGEPIPQHALHATYVKATTDADISRPYHMSIVPEKPKAINDVRLRSPQFNQHRRDYSVKEQRPIPVVVPEDARPEDSLQSYKCQVCPVSMRTVNELQVHCFVEHNIETDSSTNIHGDRSAGKCREKENTQKRIMDESVVKEDHKRQRIEDT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00015593;
90% Identity
iTF_00014945;
80% Identity
-