Basic Information

Gene Symbol
-
Assembly
GCA_017607525.1
Location
JAANIA010000992.1:10757450-10762541[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 5.6e-05 0.0032 16.9 1.6 2 23 300 321 299 321 0.97
2 11 2.2e-05 0.0013 18.2 1.4 1 23 329 352 329 352 0.97
3 11 0.00066 0.038 13.6 2.7 1 23 392 414 392 414 0.98
4 11 4.3e-07 2.4e-05 23.6 1.5 2 23 469 490 468 490 0.97
5 11 5.4e-05 0.0031 17.0 1.1 1 23 495 518 495 518 0.95
6 11 0.00011 0.0063 16.0 0.3 1 23 564 586 564 586 0.97
7 11 7.4e-07 4.2e-05 22.9 1.7 1 23 596 618 596 618 0.96
8 11 1.7e-06 9.6e-05 21.7 1.2 1 23 624 646 624 646 0.99
9 11 8.5e-06 0.00048 19.5 0.2 1 23 652 674 652 674 0.98
10 11 3.4e-05 0.002 17.6 4.5 1 23 680 702 680 702 0.98
11 11 0.00097 0.055 13.0 0.5 1 21 708 728 708 729 0.94

Sequence Information

Coding Sequence
ATGGCAGTTCCGAACGATGACGCGATGAATAACACAGCACGCGTGAAACAGCTCGTGGGTGACGAATGCCGCATCTGTCTCAAGTCCTGCACGGAGGCGTGCCAGCTTTTCCACAACGACAGCGGGATACCGGAGAAGTTGACGGCTATCGCCGCTGTACAGGTGGAGATAGGGGATGGTCTGCCAGCTTATATCTGTTCAGCTTGCAATGATTTGCTCGACGTGTCCTATGACTTCAGAGTCCAAATTCAGAACGCCGACGAGAGGCTACGGCAGTTTTTGAAGTTGCAGATTCCTATGCTGCACGACAAACATGCGAAAGATAGTATGATAATCAAAGATATTGCGGATGTCATATCTGATGTAGTATCTTGTAAAAGAGGTAATCGTATAGAGCAAGGTATTTCCTCGTCTCATGATATCGTTGCGTTTAATAATACTATCGTTCAGTCTGATATGGTAATTGATGAATCTCACATAAGTCACAAGATACAAAAAACGACAGAAATTATAGAACCAAGTGAAAAAGATGTATTGTACGGTACAGTTAAAGATAATGTACATAATGTTGAAACGATAGAAGTAGCCTTGTGTCATGAGACACACATGGATGATGCAGTTGCTGATCATTCAGATCGATTTTCCAGTTCAACAACGGAAGACAGATGTATCAAACAAGAAGATTTAATACTACCTGAAGATAATGAGACATCGGGAAATTTAACAGATGAAAATAGAGaagatacattaaaaattgaagcTAAAAATGATGCATTACTGGAGAATTTTAATGACCACATTTCGAAGGAAACCATGGTGTCAAGAATGGATACGAAAAGCGTCATAAATTGTAGTGATGACGAGGAAAAACCACTTATAAGCAGGACAACGAGACAGAAATGCTTGCATTGCATCAAATCATTTGCGACAAAAGTTGCGTTGCAGCGACACATGAACGTACACAAACACAAGACAAAGCTATGTTACGTGTGTGTCGTGTGCGACAAGCAGTTCTCGAATATCGAGAAATTGAAGAGTCACATGCTCATGTGTCACGAGACGATAGATAGTAAAGCGTCACAAGATGACAGAAAGACAAATAAAGTGTCGGCGAAAGTTACTAGAAGTAGCATCGTGACGGATAGCACGagggaagaaaagaaaaatttcaagtttaCATGCAAAGTCTGCTcgaaacaatttatatatcagaAATCCTTTTTGTCTCATGCCAAAAGTCATGTTGAATATAACGTGGATACATCGGATGATGTACTTGAGCAATCTGCGAATGATACAACGAATGAACAAAAAGATAGAATGCCAATATTCAGAGAAAATGAATCcgaggaggaagaagaagaagaggatgATGATGATAGTGATTTACCGATCAAAAGTCTACAGTGTACTCAGTGCGGCAAACTTTTTGCTACAAAGAGAAACCTGAAAAGGCATATCTCGACGCACAGTGgcttgaaatttaattgttcgACATGCGGTAAAGGATTTTCGAGAATCGACAAGTTGAAGGATCACGAACAATCGAAACACAAAGAGGAAATATTCGGCAACACTGACGATGAAGATGATTACGAGGAGGATAACGAGAGTAAAATCAACGAGAATTCCGAAAATCGAAAGAAGGCAAGTATTTTATGTGAATTctgtGACCGACACAACAGGCCACATAAGTGCATGCTTTGTCCAAAGGCTTTCGCACAAGCTCAATCTCTAGCAAACCACGTAGAGAGGCATAAACGGGTGAAGGACACGCAGAAACGATTTCTCTGCGAGAAATGTAGCAAGTGCTTTGCTCAGAGTGGGTCGCTGGTGGCACATATGCGTACACATACCGGCATCAAGCCATATGTATGCAACGTATGCAGTCGTGCCTTCACCAAGAGCACGTATTTACAGTTGCATCTGAGAACTCATAGTGGTGAGAAACCGTATATTTGCCAGTATTGTAGTAGAGCGTTTGCCCGGGCCAATACTCTGGCGCGGCACATCACCATGCATACTGGTGAGGCCAAATATCATTGCAACATCTGCACCAAGTCCTTCCGACGATTGACTTCGCTGAACgaacatacatatacacatactgGTCAACGACCGTACGCGTGCAAGCTCTGTACTAAAAGATACAACAATGCCGGCTCGTTATATGCTCATACGAAGAAATGCAAGGCGCAGCAATTGTCCAACTCGACAACGTCTGCATATGCGGTATCCACGGCAGATAATGCGCCGCAGCAGAACGACGCGTCTATGCCCCTATTAATATATTCCCAGAGGAAGCTGGTAGAAGAAGCGGCTGTTGGTCAAGTTGTATCCACGCCGCAATATATGGTAACAAATGTGCACAATCAAAAAACAATATCGCCCAACGTAATCCAACCGTACGCCGTAGAGGATCCGAATATGTACAATTCAAAACAGTTTAAGAACTCGTATTATGCTATTTATCcaaatatgcaa
Protein Sequence
MAVPNDDAMNNTARVKQLVGDECRICLKSCTEACQLFHNDSGIPEKLTAIAAVQVEIGDGLPAYICSACNDLLDVSYDFRVQIQNADERLRQFLKLQIPMLHDKHAKDSMIIKDIADVISDVVSCKRGNRIEQGISSSHDIVAFNNTIVQSDMVIDESHISHKIQKTTEIIEPSEKDVLYGTVKDNVHNVETIEVALCHETHMDDAVADHSDRFSSSTTEDRCIKQEDLILPEDNETSGNLTDENREDTLKIEAKNDALLENFNDHISKETMVSRMDTKSVINCSDDEEKPLISRTTRQKCLHCIKSFATKVALQRHMNVHKHKTKLCYVCVVCDKQFSNIEKLKSHMLMCHETIDSKASQDDRKTNKVSAKVTRSSIVTDSTREEKKNFKFTCKVCSKQFIYQKSFLSHAKSHVEYNVDTSDDVLEQSANDTTNEQKDRMPIFRENESEEEEEEEDDDDSDLPIKSLQCTQCGKLFATKRNLKRHISTHSGLKFNCSTCGKGFSRIDKLKDHEQSKHKEEIFGNTDDEDDYEEDNESKINENSENRKKASILCEFCDRHNRPHKCMLCPKAFAQAQSLANHVERHKRVKDTQKRFLCEKCSKCFAQSGSLVAHMRTHTGIKPYVCNVCSRAFTKSTYLQLHLRTHSGEKPYICQYCSRAFARANTLARHITMHTGEAKYHCNICTKSFRRLTSLNEHTYTHTGQRPYACKLCTKRYNNAGSLYAHTKKCKAQQLSNSTTSAYAVSTADNAPQQNDASMPLLIYSQRKLVEEAAVGQVVSTPQYMVTNVHNQKTISPNVIQPYAVEDPNMYNSKQFKNSYYAIYPNMQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01476429;
90% Identity
iTF_01477803;
80% Identity
-