Basic Information

Insect: Protodeltote pygarga
Gene Symbol: Tox4
Assembly: GCA_936440985.2
Location: CAKZFI020000195.1:673670-697113[+]

Transcription Factor Domain

TF Family: HMG
Domain: HMG_box domain
PFAM: PF00505
TF Group: Other Alpha-Helix Group
Description: High mobility group (HMG) box domains are involved in binding DNA, and may be involved in protein-protein interactions as well. The structure of the HMG-box domain consists of three helices in an irregular array. HMG-box domains are found in one or more copies in HMG-box proteins, which form a large, diverse family involved in the regulation of DNA-dependent processes such as transcription, replication, and strand repair, all of which require the bending and unwinding of chromatin. Many of these proteins are regulators of gene expression. HMG-box proteins are found in a variety of eukaryotic organisms, and can be broadly divided into two groups, based on sequence-dependent and sequence-independent DNA recognition; the former usually contain one HMG-box motif, while the latter can contain multiple HMG-box motifs. HMG-box domains can be found in single or multiple copies in the following protein classes: HMG1 and HMG2 non-histone components of chromatin; SRY (sex determining region Y protein) involved in differential gonadogenesis; the SOX family of transcription factors [1]; sequence-specific LEF1 (lymphoid enhancer binding factor 1) and TCF-1 (T-cell factor 1) involved in regulation of organogenesis and thymocyte differentiation [2]; structure-specific recognition protein SSRP involved in transcription and replication; MTF1 mitochondrial transcription factor; nucleolar transcription factors UBF 1/2 (upstream binding factor) involved in transcription by RNA polymerase I; Abf2 yeast ARS-binding factor [3]; yeast transcription factors lxr1, Rox1, Nhp6b and Spp41; mating type proteins (MAT) involved in the sexual reproduction of fungi [4]; and the YABBY plant-specific transcription factors.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 1.2e-18 8.1e-16 58.4 0.2 1 69 306 374 306 374 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	1.2e-18	8.1e-16	58.4	0.2	1	69	306	374	306	374	0.98

Sequence Information

Coding Sequence: ATGTGGCTTTGGGATGAACAGCAGCGCCATCGCCTTGTCGTGGTGGCTGGTGGTACTAGATGGAGGCGAGGCGCGGCGCCCCACCGCAGCGCACGCCACGACCGCCACGCAGTCTTCCCGCGCGGTTCGCACGTGCGTCTAGCGTGCCTTTCTATCGTGCTTCTACTAAATGTTACCAGACCAGAAAACCTCGAGTCTCCGCTGCCTGTTCCTCGCGACACAAAGAACAGCATATACATTATGAATGATCAGACATTTCACACACCATCATTTGGCGACGAAGAATTTGACATACCATTAATCCATGGGCAACATGCCACAAACGCCAGTGTACAAAACTCCCATATACAGTATACCCAATTGCACCACTCAGCACCGCAGGTTGGCATGATGAACCCTGCACAAGATGGCTTAGCACCACCGGGCGGCGCTCCTTCGTATCAACAACCTCTATATTTACAAGAACCGCATACACCAGTCACATCACATAGTGGAGCAGGTGCACCAGCTGGTAACTACATGATCCAGCAACAACCTGGAGGACAGCAGAGGTTACTGATGATGCAACCAACTCAAGTCATGAGTGGTCCACCAACCCCCAGTACACCCACACAACCTTCTGGTCCAGTGTATGGATCACCACAAAGGGCATCACCTCCCGGCACTACCAGTGATGATTCTGATGACAGTGTGCCTTCACATCATTCACAGTTGCCTGGTGATGCGGAAAGCCTTCTGCCTATCCATTATTGCTCAGCGAGCCGGCAGCAACAAACTACGCTTCATCAGATGGGCGTTGGTAATATGGCTGTAAAAAGATCGTCACCTGAACCCATGGACAATGGTATGAATCGTGGACAGATGCAAAAAAAGCCTAAAGTACAGAAAAAGAAGAAAAAACGAGATCCTAATGAACCTCAAAAGCCTGTATCAGCGTATGCATTATTCTTCCGGGACACGCAAGCAGCAATAAAAGGTCAAAATCCAAATGCAAGTTTTGGTGAAGTATCTAAAATTGTTGCTTCCATGTGGGATGGCCTAGACTCAGAACATAAAAGTGTCTATAAACAAAAAACTGAAGTTGCCAAGAAAGAATACCTTAAAGCGCTTGCAGCCTACAGAGCCAGTCTTGTATCCAAGGGTGGAGGAGAACAGGACACTCAAGCAATGTATAATCACACCAATAGTGCCAATCCGTCCTATGGTAATTATTACCAAGGACAAACATATGGTAATGGTCACTCGCCTCAAGGTTATGTGCCAAACCCAGTGCCACAAGGTTACTCTCCACAGAACTACTCTGGTACCCAACCACAGGCGCCTTATCCGGCTCAGACACCACAAGGATATCCACCAAACCCTCAACAATCTCCACAAAACTATCAAGGCAGCATGACTCTTACACCTCAAACATACCAGGGTGTTCCGGGTCAGTCTCCACAAGGGTACCAAGTAAACCCATCTACTTCACCTCAAAGTTGCCAGCCTAATCTTGCCCAATCACCAAGGAACTATCAACCTGCACAATCACCTAATAGCTATGCAGCAAACTCAGCTGTATCACCACCAGGATATAGACAAGTGCAGTCACAGTCACCTCCAATGGGCTCAGTGCATGCGGCTATGCAATATCATCACTCACAGCAGcacatgcaacaaacacatcagcaaatgcaacaggcacaccaagtgcagcaataccagcagcaacaacaacaacagcaaatgcatcaacagcaacaacagcagcagcaacaacaacaacagcagcagcaacaacaacaacagcagcagcagcagcaacaacaacagcagcagcagcaacaacagcagcagcagcagccatctcagcagcaacaggcgccgaatcaaattccgaaacctgaacaacactcttcaaATAGTAATGGAAACTCTGGTGTTCCACAGCAGGCATCTGATCAAAATGAAAATCGAAGTACGCCATCATGCATCCGACAGGGGTGCCCCAACCCAGCTATTGCAAACAGTGAGTGGGAGGATGAATACTGCTCCAATGAATGTGTTGTTAGTCACTGCAGAGACGTCTTCAGTTCGTGGGTGGCTTCCAATAACAGTAACCAAATTCAAAATTTCTCAGCTGTGAAATAA
Protein Sequence: MWLWDEQQRHRLVVVAGGTRWRRGAAPHRSARHDRHAVFPRGSHVRLACLSIVLLLNVTRPENLESPLPVPRDTKNSIYIMNDQTFHTPSFGDEEFDIPLIHGQHATNASVQNSHIQYTQLHHSAPQVGMMNPAQDGLAPPGGAPSYQQPLYLQEPHTPVTSHSGAGAPAGNYMIQQQPGGQQRLLMMQPTQVMSGPPTPSTPTQPSGPVYGSPQRASPPGTTSDDSDDSVPSHHSQLPGDAESLLPIHYCSASRQQQTTLHQMGVGNMAVKRSSPEPMDNGMNRGQMQKKPKVQKKKKKRDPNEPQKPVSAYALFFRDTQAAIKGQNPNASFGEVSKIVASMWDGLDSEHKSVYKQKTEVAKKEYLKALAAYRASLVSKGGGEQDTQAMYNHTNSANPSYGNYYQGQTYGNGHSPQGYVPNPVPQGYSPQNYSGTQPQAPYPAQTPQGYPPNPQQSPQNYQGSMTLTPQTYQGVPGQSPQGYQVNPSTSPQSCQPNLAQSPRNYQPAQSPNSYAANSAVSPPGYRQVQSQSPPMGSVHAAMQYHHSQQHMQQTHQQMQQAHQVQQYQQQQQQQQMHQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQPSQQQQAPNQIPKPEQHSSNSNGNSGVPQQASDQNENRSTPSCIRQGCPNPAIANSEWEDEYCSNECVVSHCRDVFSSWVASNNSNQIQNFSAVK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01094917; iTF_00449104; iTF_01085235; iTF_00018165; iTF_00850741; iTF_00851800; iTF_00275265; iTF_01403427; iTF_00077479; iTF_01336842; iTF_01075437; iTF_00827951; iTF_00150547; iTF_01501113; iTF_00844348; iTF_00640321; iTF_00745697; iTF_01285538; iTF_01170596; iTF_01487699; iTF_00450109; iTF_01443843; iTF_01509601; iTF_00273602; iTF_00123375; iTF_01134787; iTF_00356196; iTF_01529188; iTF_00662220; iTF_00661279; iTF_00034725; iTF_00035655; iTF_00784390; iTF_00318088; iTF_00119593; iTF_01135753; iTF_00325378; iTF_01342217; iTF_00267179; iTF_01171467; iTF_01282284; iTF_00157199; iTF_00706961; iTF_00632751; iTF_00856623; iTF_00811027; iTF_01279252; iTF_00361621; iTF_00696469; iTF_00698311; iTF_00284536; iTF_01219769; iTF_00638639; iTF_01197723; iTF_00651741; iTF_01220650; iTF_00146423; iTF_01335933; iTF_00683358; iTF_01528288; iTF_00737476; iTF_01020292; iTF_00318853; iTF_00382613; iTF_00279110; iTF_00447143; iTF_00301174; iTF_00445178; iTF_00302108; iTF_00446142; iTF_00120509; iTF_00667489; iTF_00147458; iTF_01526018; iTF_00121443; iTF_01441091; iTF_01028292; iTF_01119332; iTF_00425382; iTF_00907046; iTF_00374119; iTF_00907879; iTF_01026183; iTF_01031143; iTF_00906152; iTF_01338760; iTF_00071433; iTF_00888266; iTF_01533932; iTF_00111661; iTF_00124269; iTF_00622829; iTF_01063760; iTF_01340113; iTF_00036722; iTF_00785202; iTF_01029266; iTF_00037813; iTF_00711861; iTF_00726358; iTF_00831224; iTF_01030232; iTF_00364025; iTF_00172954; iTF_01027326; iTF_01439934; iTF_01502087; iTF_00821833; iTF_00709235; iTF_01084265; iTF_01363109; iTF_01361623; iTF_00122396; iTF_00177122; iTF_01425062; iTF_01118311; iTF_01246984; iTF_00171753; iTF_00237577; iTF_01534829; iTF_01532014; iTF_00809137; iTF_00375218; iTF_00810067; iTF_01094037; iTF_00973782; iTF_01064662; iTF_01061889; iTF_00017335; iTF_00300215; iTF_00823895; iTF_01230586; iTF_01117211; iTF_01377470; iTF_00952714; iTF_00908843; iTF_01387596; iTF_01386702; iTF_01388465; iTF_01385751; iTF_00049902; iTF_00235854; iTF_00236623; iTF_01490124; iTF_00290703; iTF_00341314; iTF_00859465; iTF_01358864; iTF_00858542; iTF_00820083; iTF_01429934; iTF_00428121; iTF_00819162; iTF_01062799; iTF_01544881; iTF_01545746; iTF_01546646; iTF_01543932; iTF_01561114; iTF_01547547; iTF_00355155; iTF_00771924; iTF_00075541; iTF_01280290; iTF_01503880; iTF_00408459; iTF_01071627; iTF_00752070; iTF_01180305; iTF_01179485; iTF_00960928; iTF_00074509; iTF_00076531; iTF_01281338; iTF_01502975; iTF_01533047; iTF_00187160; iTF_00682425; iTF_00758169; iTF_01341273; iTF_00274426; iTF_00706011; iTF_00928701; iTF_00041774; iTF_00039813; iTF_00042631; iTF_00043497; iTF_00040815; iTF_00026848; iTF_00027749; iTF_01463248; iTF_00701984; iTF_00702899; iTF_00700117; iTF_00703960; iTF_00699164; iTF_00697344; iTF_00701062; iTF_01334895; iTF_00705008; iTF_01429042; iTF_01302336; iTF_00008007; iTF_00736616; iTF_00806727; iTF_01425928; iTF_00621994; iTF_00072812; iTF_00011984; iTF_00013021;
90% Identity: iTF_00711861;
80% Identity: -