Basic Information

Insect: Protocalliphora azurea
Gene Symbol: Hr39
Assembly: GCA_932273785.1
Location: CAKNZW010000072.1:1235953-1239346[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 1.6 1.1e+04 -4.4 9.6 47 151 275 388 236 426 0.41

2 3 1.1e-13 7.6e-10 39.0 16.3 1 169 498 708 498 712 0.68

3 3 5.3e-80 3.8e-76 257.4 0.7 185 408 692 903 687 903 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	1.6	1.1e+04	-4.4	9.6	47	151	275	388	236	426	0.41
2	3	1.1e-13	7.6e-10	39.0	16.3	1	169	498	708	498	712	0.68
3	3	5.3e-80	3.8e-76	257.4	0.7	185	408	692	903	687	903	0.95

Sequence Information

Coding Sequence: ATGTCTACCATTAAAACAGAAAATATAAGCGGAGTTGGAGCAGTAGTGACCACCACTACAACAGGAGGCACAACATTTCAATTACCCATAAATATGAGCAATACAGAAGGAGTCATAAGTGGCAATGGAAGTGGTAGTATAACCACCACAACCTGTACTACTACAACCACCAGAAATAATGTTTCAGTAACAAATATTAAATGTGAAGTAGATGATGGTGGCAATTCATCGTCCTCAACAAATGGCAATATTGTGTCGGTGGGATTTTATAATGGTTCAAGGACCATAAGTGGAGGAAGTGTAATAACAGCTGGTCATGGTATACGAATACCAGTGACTAAAGTGGAAGATTCAGATTCTGAAACGGAATTGACAAATATAGAAAATTTGAAAGTAACACGAAGAGTAGCTAGCTCTTCTAGTTCAGGCAACAATCATCATAATGGTCCGCGACCTATGTCTTGGGAGGGAGAATTGTCGGAGAATGAAGATACCAGAGAAGCGGAATTAATGGATACTGATACTACCATGAGTAATGGAGGCATGCAGGAACCCTCAAATGCAGTAGCTGTTATTAAGAGTGAAGCCACTACTACTACTCCCTCTATGGCGGGGGGTGGGGGGTCTTTAATTAAAACGGATACAGAACAATTAATGTTAGATGTTCATCATGCGGCATCTGGTGGTGGTATATATCATCCCAAACTTAAATTGGCTCCTACACAAAGTGATCCCATTAATTTAAAATATGAACCACCTGATCATAACGCTCTAGTGAATTCGCCTTTACTGGTGCGCCAAAAGTCTACCACAGCTTTGCCTCATTTACCTGCCAATCCAAGTCCAGATTCTGCCATACATTCCGTTTATACCCATAGCTCACCTTCCCAATCACCCTTGACCTCTAGGCATGCTCCTTATACTCCTTCACTGTCACGAAATAATAGTGATGCTTCTCATAGTTCTTGCTATTCTTACTCCTCGGAATTTAGTCCCACCCATTCTCCAATACAAGGCAGACATCCTGCGCCACATGGTGTTTATGGTAGTTTTAATGGAACCGCGGCCAATAGCTTACAACATTCCGCTTTACTCTATAGACCCATGATGGGTTCAACACAATCACCCCAATCTGCTAAATTGGAGGCAGGTTCAAGTGAGGTTCAAAATTTATCCATGGATGCATCCTCTTCTTCATCGTCGTTTAATATGACTAGTGATTCTTCGGGTTTGCCGGCCTCTCCAGCTGCTGGCATTTCCCGGCAACAGCTCATTAATTCTCCCTGTCCCATTTGTGGCGATAAGATATCGGGTTTTCATTATGGCATCTTTTCTTGTGAATCATGTAAAGGTTTTTTCAAACGTACCGTCCAAAATCGCAAGAACTACGTATGCGTACGAGGTGGACCCTGTGCCGTGAGTATTACCACACGCAAAAAGTGTCCTGCTTGTAGATTTGATAAATGTTTACAAAAAGGCATGAAATTGGAAGCAATACGAGAAGATCGTACACGAGGAGGCCGTTCTACTTATCAATGCTCCTATACTTTACCCAATTCCATAATGAGTCCTTTACTCTCACCCGAACAGCAACAGCAGCAGCAACAACAAAACTCCACACAAAATCTAATGTCCGGACAACAACATTCACAGCTACAACATCAACTCCAGCAACGTCTTAATCCTCCCCTACAATCGTCTCTTCAAACTAATGGCTATGGTGCACAAAACTCCAATTCAGCCACCTCAACTACAACCATTAAAACTGAGCAAACTGATCCTTATTTAAAGAATTTGCCTAATACCCATTCACCTTCTATGAATGGTTTAAATTCATCACGTTCACATGCTAATGTCAGCGGCAATGCTTCCTCCTCTTGCTCCTCCACCTCCGCCTCCAACAATTCACTGCATCACAACAGTATTCCCCAACTATTACAAGAAATTATGGATGTTGAACATCTTTGGCAATATACCGATGCTGAATTGGCACGACTTCATCAGCCACTGACTTCGTCGTCCAGTTCAACTTCACTTAATTCCAATTCAACAGATTCTTCTGCAGCTGCCAATCAAATGACCAATCCACTGCTGGCCAGTGCTGGTCTATCGTCTAGCACCAATCCGGATTTGATAGCACATTTGTGTAAGGTGGCCGATCATCGTTTGTATAAGATTGTTAAATGGTGTAAGAGTTTGCCGTTATTTAAGAACATATCGATTGACGATCAAATTTGCCTACTCATCAATTCATGGTGTGAACTTTTACTTTTCTCCTGTTGCTATCGTTCCATAGATACACCAGGAGAAATTAAAATGTCCTTGGGCAAAACAATAACACTGCCACAGGCTAAATTAACTGGTTTTCAGCCCTGCATTGAAAGAATGCTGAATCTGACAGATCATTTAAGACGTTTACGTGTTGATCGTTATGAATATGTTGCTATGAAAGTCATTGTATTGCTGCAATCAGATACTTCCGAATTGCAAGAACCCGTTAAGGTTAGAGAATGTCAAGAGAAGGCTTTACAAAGTTTACAGGCCTACACATTGGCCCACTATCCAGATTGTCCATCGAAATTTGGTGAATTATTGCTGCGCATACCCGATCTACAGAGAACTTGTCAGTTGGGAAAAGAAATGTTGTCCATTAAATCTCGTGACGGCAATGACTTTAACTTATTAATGGAACTTTTAAGAGGAGAACATTGA
Protein Sequence: MSTIKTENISGVGAVVTTTTTGGTTFQLPINMSNTEGVISGNGSGSITTTTCTTTTTRNNVSVTNIKCEVDDGGNSSSSTNGNIVSVGFYNGSRTISGGSVITAGHGIRIPVTKVEDSDSETELTNIENLKVTRRVASSSSSGNNHHNGPRPMSWEGELSENEDTREAELMDTDTTMSNGGMQEPSNAVAVIKSEATTTTPSMAGGGGSLIKTDTEQLMLDVHHAASGGGIYHPKLKLAPTQSDPINLKYEPPDHNALVNSPLLVRQKSTTALPHLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQGRHPAPHGVYGSFNGTAANSLQHSALLYRPMMGSTQSPQSAKLEAGSSEVQNLSMDASSSSSSFNMTSDSSGLPASPAAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCAVSITTRKKCPACRFDKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSIMSPLLSPEQQQQQQQQNSTQNLMSGQQHSQLQHQLQQRLNPPLQSSLQTNGYGAQNSNSATSTTTIKTEQTDPYLKNLPNTHSPSMNGLNSSRSHANVSGNASSSCSSTSASNNSLHHNSIPQLLQEIMDVEHLWQYTDAELARLHQPLTSSSSSTSLNSNSTDSSAAANQMTNPLLASAGLSSSTNPDLIAHLCKVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCYRSIDTPGEIKMSLGKTITLPQAKLTGFQPCIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTSELQEPVKVRECQEKALQSLQAYTLAHYPDCPSKFGELLLRIPDLQRTCQLGKEMLSIKSRDGNDFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01259264;
90% Identity: iTF_00045401;
80% Identity: iTF_01259264;