Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 1.7 1e+03 0.9 0.1 23 47 34 58 27 65 0.71

2 8 1.9 1.1e+03 0.7 0.0 21 44 60 83 48 87 0.77

3 8 0.021 13 7.0 0.2 21 44 88 111 85 115 0.91

4 8 0.013 7.5 7.7 0.0 21 46 116 141 112 147 0.86

5 8 0.23 1.4e+02 3.7 0.0 21 44 144 167 142 173 0.89

6 8 0.31 1.8e+02 3.3 0.0 26 44 203 221 198 227 0.88

7 8 0.44 2.6e+02 2.8 0.0 22 44 247 269 240 273 0.84

8 8 0.07 42 5.3 0.1 21 44 274 297 271 306 0.87

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	1.7	1e+03	0.9	0.1	23	47	34	58	27	65	0.71
2	8	1.9	1.1e+03	0.7	0.0	21	44	60	83	48	87	0.77
3	8	0.021	13	7.0	0.2	21	44	88	111	85	115	0.91
4	8	0.013	7.5	7.7	0.0	21	46	116	141	112	147	0.86
5	8	0.23	1.4e+02	3.7	0.0	21	44	144	167	142	173	0.89
6	8	0.31	1.8e+02	3.3	0.0	26	44	203	221	198	227	0.88
7	8	0.44	2.6e+02	2.8	0.0	22	44	247	269	240	273	0.84
8	8	0.07	42	5.3	0.1	21	44	274	297	271	306	0.87

Coding Sequence: ATGCACGGCGAAGCGGGGATACTCAAGTGCGTTCATTGCGGTTGCAAATTCGAAGAAACCGACGCGCTGAAGCTGCACACGTCGACGCACGCCGGCGAGAAGCACTTCCGCTGCGAACTCTGCGACTACGAGTGCGTCAAGCCCGGCAACTTGAAGCGGCACATGTTGATACACACCGGAGAGAAGCCCTTCAACTGCGACTTTTGCGATCATAAATTCCGAGACCACGGCAAGCTGAAAGAGCACATGCTAACGCACacggacgagaagccgttcacttGCGAGCTCTGCGAGCATAAGTGCCGGAGGCCCGGGGATTTGCGGCAGCACATGTTGACGCACTCCGGCGAGAAACCGGTCGCTTGCGATTTTTGCGGTTACAAGTGCAGAAAACTCGGCGACTTGAGGCGGCACATGCTGGTGCACACCGGGGAGAAGCCGTACGGTTGCGTtttttgcgattacaagtgccgggATGGCACTAATTTGAAGAAGCACGCGCTAACGCACACGTACAGGTACAGCTGTGGCGTTTGCGACTACAAGTGCCAGAAGTTTTTGGAtctgaaacagcacgtgctggTACACACCGATAAAAAAGTGTACAGTTGTgacgtttgcgattataaaagcCGACAGCTTGCCACCTTGAAGCGGCACTTGTTGACACACCCCGGTGCGTTCATTGCGGTTGCAGATTCCGAAACGTTGAAGCTGCACACGTCGACGTACGCCGGCGAAAAGCACTTTCGTTGCAAGCTTTGCGGCTTCGAATGCAAAAAATCCGGCAATTTGACGCGGCACATTTTAACGCACACCGAAGAGAAGCCGTTCGCCTGTGACGTTTGCGGTCGCAGATTTCGACAGCGCGAATCGCTGAAAGCGCACATGATCACGCACAGCGACGAAAAGCCGTTCGAGTGCGACTTTTGCAGTTACAAATGCCAAAGGCCCGGTGATTTGAACAAGCACATGCCAACatacaccggcgagaaaccgtgtTTTGCGTCTATAAATGCCGTACGCTGGCTGAGTTGA
Protein Sequence: MHGEAGILKCVHCGCKFEETDALKLHTSTHAGEKHFRCELCDYECVKPGNLKRHMLIHTGEKPFNCDFCDHKFRDHGKLKEHMLTHTDEKPFTCELCEHKCRRPGDLRQHMLTHSGEKPVACDFCGYKCRKLGDLRRHMLVHTGEKPYGCVFCDYKCRDGTNLKKHALTHTYRYSCGVCDYKCQKFLDLKQHVLVHTDKKVYSCDVCDYKSRQLATLKRHLLTHPGAFIAVADSETLKLHTSTYAGEKHFRCKLCGFECKKSGNLTRHILTHTEEKPFACDVCGRRFRQRESLKAHMITHSDEKPFECDFCSYKCQRPGDLNKHMPTYTGEKPCFASINAVRWLS

Sequence clustering based on sequence similarity using MMseqs2