Basic Information

Insect: Portevinia maculata
Gene Symbol: Foxk1_1
Assembly: GCA_949715645.1
Location: OX454529.1:12517972-12522664[+]

Transcription Factor Domain

TF Family: Fork_head
Domain: Fork_head domain
PFAM: PF00250
TF Group: Helix-turn-helix
Description: The fork head domain is a conserved DNA-binding domain (also known as a winged helix) of about 100 amino-acid residues. Drosophila melanogaster fork head protein is a transcription factor that promotes terminal rather than segmental development, contains neither homeodomains nor zinc-fingers characteristic of other transcription factors [1]. Instead, it contains a distinct type of DNA-binding region, containing around 100 amino acids, which has since been identified in a number of transcription factors (including D. melanogaster FD1-5, mammalian HNF-3, human HTLF, Saccharomyces cerevisiae HCM1, etc.). This is referred to as the fork head domain but is also known as a 'winged helix' [1, 2, 3]. The fork head domain binds B-DNA as a monomer [2], but shows no similarity to previously identified DNA-binding motifs. Although the domain is found in several different transcription factors, a common function is their involvement in early developmental decisions of cell fates during embryogenesis [3].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 7e-40 3.2e-36 125.8 0.3 1 86 464 549 464 551 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	7e-40	3.2e-36	125.8	0.3	1	86	464	549	464	551	0.97

Sequence Information

Coding Sequence: ATGACGGATAATAACAATTCTTATCAGGTACAACATCAGGACAAATCACCAGTTAACTCTCCCATCATCCACCATCAGTCGCCGAACCACGCTGTTGTGATTAAACAGGAACACTTGGTACACGACTATATTGAGGAGAGCCCTCCGCCGACTACGTCTTACTCGCGTAAGCAGAACTTTTCAAAGTCGCCAACCATTGACCAACAAAAGCAGCAGCAAGATCTACTTAGCTCACCAAACGAACATCAACAGCACAATTATTCATCAAACATCTATCAGGAGAGAGTGACAACATCGGGTGTATCCTCGCCGGAAATACGAGGCATTGAACGTGCAggcggaggaggaggaggaggaggtagTGGCGGTAACGATAGTGGCTGGAACGATGCCGATGAGGATAATGACAACAGAAGTTCTCCAAACGTCACATCCAGTCGAACAGAGAGCAGCACTGCTGGTGGCAGGATCTATTTAAACACCTCCAATAGTAGCAACAATCGTGCGCGAATTTCATCATCGCCGCTCCCGCCACCGCCACCGGCGCACTCGTACTCCCGTCTACCGGTTCAACAGAGCGCCAACAACAGGAATCGAGTCTCGCCAACCAACTGGCATCAGCCACAAAATCAACTTGACTATATCCACCAGCAACAGCATCACCAGCAGCTAATAGTTAACGACGAAATGCTGCAAGCTCAACAGAGCCACATGCAACAGGCTCCCAATAATGCATGCGGCATGCTGAAGCACGAGAATGACATCCTTTACATTACAGAAAACTGTATAGAAATCGGACGAAATTCTTCCACTTCGCATGTTCACTTTCATGTCGCCCGCAATAGTTTTGTCTCGCGCAAACACTTTCAGGTACTCTATGATCCAGATACTTGCGACTTTTATGTCGCCTGCCTGAGTAAGAATGGGGTGTTTGTGGATGACGTTTTCCAGCGACGATACGCTGAACCaatgaaattaccaaaaagttgttcCTTTCGATTTCCGAGCACAGAAATAcgaattttatttgaaagtttTGTCGATTCAACATCATCCTTGCATGCAAATACAATAGTTTCTACAAACAGTGCACCCACCAGTAATAGCTCGTCGAAAATGCATTATTTCTCTGATCGCAAGAATCTAAATGCAACATCAATTGAAGGCTCAAATGTGATATATTCACCATTGAAAATTTCAATACCCAAAACTGAACAGAAAAGTCCATATCCTTCGCCCACCGGTACAATTAGTGCTGCAAACAGTTGCCCTACAAGTCCACGACAAGGTTTTCAAGACTATCAAAGCTACAGTAGTTATACCAATAACAACAACTTGCAAGGCCAAGAGCTGTTTCAAACTCCATCAACTTCCAATTACAATGACCATGAAAAGCCACCATACAGCTATGCCCAGCTAATTGTTCAATCAATATCTGCAGCGCCCGACAAGCAGCTTACATTATCCGGGATTTATTCcttcatttcaaaacattatCCATACTACCGCAAAGAAGCCAATAAGGGTTGGCAGAATTCAATTCGTCATAATCTCAGTTTAAACAGATATTTCATAAAAGTTGCACGATCTCAAGATGAACCAGGCAAAGGTAGCTTTTGGCGTATTGATCCTACCAGTGAAGCTAAGCTAATTGACCAAAGTTATAAAAAACGCCGACAACGCGGCAGTCAATGTTTCCGACCATCATACGGTATGCCGCGATCAGCGCCTGTTTCACCAAGCCACATTGATAATTCTCGTGAAAGCTCCCCGCTGCATGATATTGTCTTGCAGTCAGCACCTGGCTCTCCAGGAATTTCTTATCAGGGTCATTTGGAAAACCATTCAGCGGAAGACTTGATGTACAGCTCTCAACCTGTTATCCAACCATCATCCTACAATGCACATAGTCAATATAGCTCAAGCGGACAACAGCAATCGATAATCGTATCAACTTCTGGACAAATAACAAACAATGGCAATGGTAACAACGTCAATGGGGGAAGTACTTTAATTGCCATCAAACGGCATCATTCAGCAACCGTGACATCTGCGCAATCACACGCCCCCGGTAGTACGCAACATCATCAAGATACTACTTATGACGACGGGCAAGAGTACAATAGTGGAGCTGGCGGTCCCGCCATCGATAGTGGCGACGAATGCGATACTATGAAACGGCCAAAATACGCTCCTGACATGAATCAGTAG
Protein Sequence: MTDNNNSYQVQHQDKSPVNSPIIHHQSPNHAVVIKQEHLVHDYIEESPPPTTSYSRKQNFSKSPTIDQQKQQQDLLSSPNEHQQHNYSSNIYQERVTTSGVSSPEIRGIERAGGGGGGGGSGGNDSGWNDADEDNDNRSSPNVTSSRTESSTAGGRIYLNTSNSSNNRARISSSPLPPPPPAHSYSRLPVQQSANNRNRVSPTNWHQPQNQLDYIHQQQHHQQLIVNDEMLQAQQSHMQQAPNNACGMLKHENDILYITENCIEIGRNSSTSHVHFHVARNSFVSRKHFQVLYDPDTCDFYVACLSKNGVFVDDVFQRRYAEPMKLPKSCSFRFPSTEIRILFESFVDSTSSLHANTIVSTNSAPTSNSSSKMHYFSDRKNLNATSIEGSNVIYSPLKISIPKTEQKSPYPSPTGTISAANSCPTSPRQGFQDYQSYSSYTNNNNLQGQELFQTPSTSNYNDHEKPPYSYAQLIVQSISAAPDKQLTLSGIYSFISKHYPYYRKEANKGWQNSIRHNLSLNRYFIKVARSQDEPGKGSFWRIDPTSEAKLIDQSYKKRRQRGSQCFRPSYGMPRSAPVSPSHIDNSRESSPLHDIVLQSAPGSPGISYQGHLENHSAEDLMYSSQPVIQPSSYNAHSQYSSSGQQQSIIVSTSGQITNNGNGNNVNGGSTLIAIKRHHSATVTSAQSHAPGSTQHHQDTTYDDGQEYNSGAGGPAIDSGDECDTMKRPKYAPDMNQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00724576; iTF_00310817; iTF_00315745; iTF_00313253; iTF_00312394; iTF_00314955; iTF_00311608; iTF_00314073; iTF_01520774; iTF_01522370; iTF_01521684; iTF_00671409; iTF_00240469; iTF_00310025; iTF_01541963; iTF_01541235; iTF_01223192;
90% Identity: iTF_00724576;
80% Identity: -