Basic Information

Gene Symbol
Trl
Assembly
GCA_004785975.1
Location
SMLS01039893.1:3008-4330[+]

Transcription Factor Domain

TF Family
zf-GAGA
Domain
zf-GAGA domain
PFAM
PF09237
TF Group
Zinc-Coordinating Group
Description
Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 1.2 9.1e+03 -2.3 0.7 5 22 154 171 152 175 0.71
2 3 2.2e-14 1.7e-10 41.6 0.4 14 44 229 259 224 263 0.94
3 3 2.3 1.8e+04 -3.3 0.1 18 29 308 319 302 322 0.79

Sequence Information

Coding Sequence
atgtcttCGGGGCAATTATACAATTTGACATGGGGAGAATATGGTACGTCATTAATATCAGCTGTACAATTGCTTCGCTGCCAAGATGAATTGGTGGATGTTACTCTAGCAGCTGGAGGTAGAACATTTCACGCACATAAAGTTGTATTGTGCGCTGCAAGCCCGTTCTTACTAGATTTATTAAAGAGTACTACTTGTAAACATCCAGTTGTCATGCTAGCTGGAGTCCAGGCATCTGATTTGGAGGCGCTATTAGAGTTTGTGTATCGAGGCGAAGTTAGTGTCGATCCTAGCCAATTACCGTCTCTATTACAAGCTGCACACTGCTTAAATATACAAGGATTATCTCCGACACATACGAGTAATGATTCTCTACAACATGTATTAAAAACTGAGAAAGCGCAAGATCTGGTACATCCGCAAGTTAGTTTAAGTTTAGAGGATGAATCgatattgaaaaggaaaaagCGAGTAAAACGGATGAGGAGTCCCATAAGCCAGAGTCAGAGTAGTAAATGGTCGAAACCGTACATCCAAACCGATGGAAATGCCCCTAGTTGGACCCAACAAATGAATCTCGTAAATGTCCCATCATCAGCAGCAGCCCTCACTAATATTCCACTACACACACCGATTTTGGTACAAAATGTACCCGTATCCGTTAATAGTACCGCACAAAATTCGACACCCAAAGTTCGGGGTGCATCGGATCAACCAGGCACATGTCCATTGTGCGGAGCTATGTTACGGCAAGCTAGGAATTTAAGAAGGCATCTTATAACAAGTTGTAAATATCGTTCGATGAGTAACCAATCTAATATGACGAATACACAGCACGTGGAAAGGACTTCGAATGGCACCTTACATCAACTACAAACGATACCTTTACAGAATGTCGAACGCGTATCCCAGAATATCGAGAGGATTGACAGTAAACAGATGGCTTTGACACCGATATCGTGTAGTGATCTGTTACCTTCGACGTCTAATATAATGTCGAATAGTTTGCAATAG
Protein Sequence
MSSGQLYNLTWGEYGTSLISAVQLLRCQDELVDVTLAAGGRTFHAHKVVLCAASPFLLDLLKSTTCKHPVVMLAGVQASDLEALLEFVYRGEVSVDPSQLPSLLQAAHCLNIQGLSPTHTSNDSLQHVLKTEKAQDLVHPQVSLSLEDESILKRKKRVKRMRSPISQSQSSKWSKPYIQTDGNAPSWTQQMNLVNVPSSAAALTNIPLHTPILVQNVPVSVNSTAQNSTPKVRGASDQPGTCPLCGAMLRQARNLRRHLITSCKYRSMSNQSNMTNTQHVERTSNGTLHQLQTIPLQNVERVSQNIERIDSKQMALTPISCSDLLPSTSNIMSNSLQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00308134;
90% Identity
iTF_01252952;
80% Identity
iTF_01252952;