Basic Information

Insect: Polyplax serrata
Gene Symbol: Hr39
Assembly: GCA_037055365.1
Location: JAWJWE010000004.1:8593738-8597373[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.057 2.3e+02 0.4 2.7 87 172 209 302 148 375 0.58

2 3 1.9e-09 7.7e-06 25.0 0.0 1 32 497 528 497 545 0.89

3 3 6e-72 2.4e-68 230.9 0.0 159 408 552 808 533 808 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.057	2.3e+02	0.4	2.7	87	172	209	302	148	375	0.58
2	3	1.9e-09	7.7e-06	25.0	0.0	1	32	497	528	497	545	0.89
3	3	6e-72	2.4e-68	230.9	0.0	159	408	552	808	533	808	0.94

Sequence Information

Coding Sequence: ATGGACGCGACGGCCACAAGCGCAAGTTGGACTCAGGCAGCGAGCAGACTTGTACCACAAAATTCTCCAACCAAGGGAGTAGTGTCGGTCGTGGTCGACTCCAGAAACGACGGATCCAATGTTTTTGCCGTGAAAGAGGAGCACATTGTTGGTCGAGGAACTTCGATTACATGTGGAGGAGTAACGGTTACTTCTATAAATGTAACGCATGAAAGAGAGCAAGAATTTCCTCAGAATGTTAAAAACACAACATATGTCGCAAATGAAAAAGCACAACAGGGAGTAAAATGTGAACCCCTTTCTTCAGTATATAATGACGATGATTCGGGATCGGATTCTGAAGTCAGCAAAATTGATTTCAGTGGTGTTCACCTTCGTATcaagaaaaagagaagcaataaaaatgacGAGAAGTCTCAGGATTTCTTTAAGAATGAAGAGCCGGAAAGACCGATGTCTTGGGAAGGAGAACTTTCCGACAGGGAAATGTCAATGGTCACCGGTGAAAGGCACATGAGAGAAGATGTTAAGGATGAACTAATGAACGAAGTTCAAATGTCACCCCAAAGGATTCCAAAGTCTGAAGTTAATGACACACTGATGGGACCCGGAAGGTTAAAGCAAGAACCGGAGGGAAGTAATGACGCTATGAGTGGTTATTCAACGTCTAGAGAGTTACCACTTCTCGTGGATAAACTACTGGGCGGTTACACCACTCCTTCACAAAGTCCGATTCTTCAACAAAGACAGCATCACTCACTGACAAAGCAACATTCTTTGTTGGGCGCGCTTCCGCCGAATCCATCACCAGATTCAGCTATACATTCCGCGTATTCTTATTCCTCGCCGGCTGCATCTCCGGCTGCATCTCGTCACTTGCCCTCCAGCGGGTTTTCCTCTCCTTTCACACCTTCACTTTCCAGGAACAATTCGGATGCGAGCCAGTATGGGGGATCACAGCACTCGTCTTGCTACAGTTATaacagtgaaaatttttccagtCCGACGCATTCGCCCATACAGGGGAGACACCTCCTCGGTTATTCAAAAGTCGATGGCAGTCCTCTGCATTCCATAACAGGGAATGTTGCCTATGGGTCTCGCGGAGTGTCAACTCCTCAAAGTGCCCTCGATGAGTCTCAGCATTTGGACAGCGAAAGAGACGAAGAGAGAGATCCCTGCCTGGAAGAGAAAATGTCGTGTTTGGCATCCGATCTTTCTCAGCATTCTGCCTTAGCGACTCCGCCAGGAATATCAAGACAGCAACTGATTAATAGTCCTTGTCCTATCTGTAGCGACAAAATTTCTGGATTTCATTATGGTATATTCAGTTGCGAATCATGCAAGGGGTTTTTCAAGAGAACCGTGCAAAATAGGAAGAACTACGTGTGTTTGAGAGGATCCCAGTGCCCGGTGACAATAGCAACTCGTAAAAAATGTCCGGCTTGTAGGTTCGAAAAATGTCTCAAAATGGGAATGAAATTAGAAGcaaTAAGAGAAGACAGGACGAGAGGGGGTCGTAGTACCTATCAGTGTTCATACAGCGTACCTTCTTCGTTACTTCAATCCAACGATTCCATGCAGAAACTTTCGAATAGTCTACCCACTGGTGAAACTCTAGTCAAGCTAGAAACACCACTTTTAGGTTCGCCAAATTCGAATTTAGATTCAAGACTGCTTCCGGTTCCACAACTATTGCAgGAAATAATGGACGTGGAACATTTGTGGCATTACAATGAGAATGAGATGCTGGGATCTCCACAAAATAATCACCGGCACTCACCCTCTTCGACGCCCTCTTCTCCGTCTCATCCGAATTCTGAAACGAATCCAGATTTTCTCTCTAACTTGTGCAATATTGCGGATCATCGCCTCTACAAAATAGTTAAGTGGTGCAAAAGTTTGCCGCTCTTCAAAAACATATCGattgaCGATCAAATTTCTCTACTAATAAATTCTTGGTGTGAACTCTTGTTGTTTTCCTGTTGCTTCCGGTCCATGTCTTCCCCGGGAGAAATTCGAGTTTCCCTCGGGAAATCTATTTCCTTATCGAAGGCGAAGGACCTTGGCCTCGGACCTTGTATCGAAAGAATGTTGAACTTCACGCAACATTTGCGACGTCTCAGACTGGACAAATACGAATACGTTGCTATGAAGGTAATCGTTCTTTTGACGAGTGACGTAAATGATTTGAGAGAACCCGAAAAGGTTCGAGCATCGCAAGAGAAGGCTCTACAGGCCTTGCAGCATTACACGCTGGCTCATTATCCCGACATGCCGTCGAAATTCGGCGAACTTCTTTTAAGAATTCCAGAACTTCAGAGAACATGTCAGGTCGGGAAAGAAATGCTTTCAATCAAAAAccgagaaggagaagaagggCCAAGTTTCAATCTCTTAATGGAGCTTTTGAGAGGCGACCACTAA
Protein Sequence: MDATATSASWTQAASRLVPQNSPTKGVVSVVVDSRNDGSNVFAVKEEHIVGRGTSITCGGVTVTSINVTHEREQEFPQNVKNTTYVANEKAQQGVKCEPLSSVYNDDDSGSDSEVSKIDFSGVHLRIKKKRSNKNDEKSQDFFKNEEPERPMSWEGELSDREMSMVTGERHMREDVKDELMNEVQMSPQRIPKSEVNDTLMGPGRLKQEPEGSNDAMSGYSTSRELPLLVDKLLGGYTTPSQSPILQQRQHHSLTKQHSLLGALPPNPSPDSAIHSAYSYSSPAASPAASRHLPSSGFSSPFTPSLSRNNSDASQYGGSQHSSCYSYNSENFSSPTHSPIQGRHLLGYSKVDGSPLHSITGNVAYGSRGVSTPQSALDESQHLDSERDEERDPCLEEKMSCLASDLSQHSALATPPGISRQQLINSPCPICSDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGSQCPVTIATRKKCPACRFEKCLKMGMKLEAIREDRTRGGRSTYQCSYSVPSSLLQSNDSMQKLSNSLPTGETLVKLETPLLGSPNSNLDSRLLPVPQLLQEIMDVEHLWHYNENEMLGSPQNNHRHSPSSTPSSPSHPNSETNPDFLSNLCNIADHRLYKIVKWCKSLPLFKNISIDDQISLLINSWCELLLFSCCFRSMSSPGEIRVSLGKSISLSKAKDLGLGPCIERMLNFTQHLRRLRLDKYEYVAMKVIVLLTSDVNDLREPEKVRASQEKALQALQHYTLAHYPDMPSKFGELLLRIPELQRTCQVGKEMLSIKNREGEEGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00362587;
90% Identity: iTF_01251105;
80% Identity: iTF_01251105;