Basic Information

Gene Symbol
-
Assembly
GCA_018290095.1
Location
CM031380.1:4998293-4999087[+]

Transcription Factor Domain

TF Family
zf-LITAF-like
Domain
zf-LITAF-like domain
PFAM
PF10601
TF Group
Zinc-Coordinating Group
Description
Members of this family display a conserved zinc ribbon structure [3] with the motif C-XX-C- separated from the more C-terminal HX-C(P)X-C-X4-G-R motif by a variable region of usually 25-30 (hydrophobic) residues. Although it belongs to one of the zinc finger's fold groups (zinc ribbon), this particular domain was first identified in LPS-induced tumour necrosis alpha factor (LITAF) which is produced in mammalian cells after being challenged with lipopolysaccharide (LPS)[2]. The hydrophobic region probably inserts into the membrane rather than traversing it. Such an insertion brings together the N- and C-terminal C-XX-C motifs to form a compact Zn2+-binding structure [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 5.3 5.2e+03 -2.3 0.1 7 15 6 14 3 18 0.60
2 3 4.2 4.1e+03 -2.0 0.1 10 27 87 104 83 107 0.76
3 3 2.4e-13 2.4e-10 40.4 4.0 4 69 164 229 162 230 0.95

Sequence Information

Coding Sequence
ATGACTTTAGTTCTTAAATGCTTAATTTGCCACgaagaaattgaatattcGAAACATAATCCAACTGAGTTAGTTAAGCATATGAAAACAGCACAtccgagagagaaaaataagcaAGTTCTTAGAGAATCTATTGAAAAAGTTGATAAGGCTATTGAAGTGTGTTTAggtgaaaatcaaaaaacattcTATAAAGTCATAGCAAAGGAAATTCAAACTGACATTGCAATGTGTGATATGGCTAATATAAGCACGTGCAAATGTGATGatgCCTTAAATACAAAAGTTGAAACAAGTGATGACGAAATTACtgaaatttatgttaataAGCAAAAGAAAACATCATCAACAATTCTCTCAAAACCAGAGAAGCGAGTTGACTTGAAatcaactaaaaataaaaatcctgaaaaagaaaaattgctaaaacataaaagacctatgaaattttataaaacatcaaTTGAACATTGGAGACCAATTGGAGATGCAAAAATTCATTGTCCACGATGCCAGTCACACAAAAGACCAGTTATAAGAAGTCAGAAGCAACATGTTACAAGTTCGTCAATCGCTTCATCATTTCTTATGGCATGTTGGCCTCTCTGTTCATCTCCTTGTTTCTTACCAGAGCCAAAGTATGAAAATCTACATTGTCCTGTTTGTAATTTTCATCTCGGTATTTTTGATCATCAAAAGAAAACTGTTTCATCAAATCCACACATAGGAgaataa
Protein Sequence
MTLVLKCLICHEEIEYSKHNPTELVKHMKTAHPREKNKQVLRESIEKVDKAIEVCLGENQKTFYKVIAKEIQTDIAMCDMANISTCKCDDALNTKVETSDDEITEIYVNKQKKTSSTILSKPEKRVDLKSTKNKNPEKEKLLKHKRPMKFYKTSIEHWRPIGDAKIHCPRCQSHKRPVIRSQKQHVTSSSIASSFLMACWPLCSSPCFLPEPKYENLHCPVCNFHLGIFDHQKKTVSSNPHIGE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01250344;
90% Identity
iTF_01250344;
80% Identity
iTF_01250344;