Ppem011000.1
Basic Information
- Insect
- Polypedilum pembai
- Gene Symbol
- ZEB1
- Assembly
- GCA_014622435.1
- Location
- JACWBX010000235.1:1459-3872[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 0.003 0.14 12.7 0.0 3 23 105 126 104 126 0.94 2 17 2.8e-07 1.3e-05 25.3 2.9 1 23 131 153 131 153 0.97 3 17 0.0041 0.19 12.2 0.3 2 23 160 181 159 181 0.96 4 17 0.00034 0.016 15.6 0.9 1 23 185 208 185 208 0.90 5 17 0.32 15 6.3 0.5 3 23 216 237 214 237 0.81 6 17 0.0011 0.05 14.0 0.6 1 23 246 269 246 269 0.93 7 17 5.6e-06 0.00026 21.2 2.4 1 23 275 297 275 297 0.98 8 17 0.036 1.7 9.2 0.3 2 21 303 322 302 323 0.93 9 17 0.00091 0.042 14.3 0.2 1 23 449 471 449 471 0.98 10 17 0.38 18 6.0 4.2 2 19 478 495 477 500 0.93 11 17 0.00028 0.013 15.9 1.0 1 23 512 534 512 534 0.98 12 17 0.014 0.63 10.6 2.3 1 23 540 565 540 565 0.98 13 17 0.00045 0.021 15.2 3.2 1 23 571 594 571 594 0.95 14 17 0.017 0.8 10.2 0.5 1 23 632 655 632 655 0.91 15 17 0.0016 0.076 13.5 0.6 1 23 664 686 664 686 0.92 16 17 0.0027 0.12 12.8 2.0 1 23 692 714 692 714 0.96 17 17 5.2e-05 0.0024 18.2 1.2 1 23 719 741 719 741 0.98
Sequence Information
- Coding Sequence
- ATGTCAAAAATTGGACAGGAGCAGTACTTGGAAGTGATTCAAGTCATTCAGCAACAGGACGCAGTTACGGAAGAAATTGATTTGATCGAATACGTGCCAGAAGAAGGTGAAGGTGGTGAAGTAGTGTATGAATTTGTAGAATTGGCACAACCAATTGAAGAAATCAAGCCTGAAATCTATGAAAAAAACTCAAACGATACTAAATTTCGTTGTGCTAATCGTTTGTGTAAACGCAGCAATGTTGTTTACGATACCAAGGAGGAACTTGATGTCCACAATGAAGTCCATATTGAGCAGTATCGAAACGCAATTTGCCCCATTTGCAACAAAGAACTCGCAAACGCGGCCAAACTTGAAAATCACATCGAGCTGCGGCATACACCGCGACATTTTACTTGTGATCAATGCGGGAAAGTTTTTCGTAGCAAGGATAATTTAAGATTGCATATGTCACATCACAGGAAGTATTTTTATGTCGAATGTAATGCTTGTGGTCGTGGCTATAAAAGCATTCAATCATTGCGTTATCATTTGAGACAACATTTTGAACATCATCAATGTGAGACTTGTGGAAAAGTCTTTGAGCATAAAAAACTTCTTCTTGGTCATGTTGCTGCAATGCATAATCAAGATTTGCAAGTTAATTGTCGTTACTGTACGAGGACTTTTGCAAGAAGTGATGTTAGAGACACTCATGAAAGAGATATTCATAAAAATGGAGCAGTTGGTTCACATTTTAAATGTAATGAATGCACAGAAACTTTTGATCTTCGAGATGATCTGATGAGTCATAAAATTTTAAATCATTTTAGTGGTGTTATTCATACTTGTCAGGAATGTGGAAAGAATTTTAAGAAAAAATCACTTTTAGATCTTCATATGAATGTTCATCGAAAGAAATCAATATCGTGTGATGTTTGTAAACAAATGTTTACATTTGTAACAGGATTGAATAAACATAAGAAATTGGGAAGATGCAAAGGTCCACCTACCGAGACACTTGCTGATGTTTTAACCAAAGAAGAAATCGCTCGAATTGCTAAAGCTCAATTACAAGAAATTACAGTAAATCCAAAGAAAGAAGTTGAAGAAGAACAGGAAAATATAGAGCAAGAAATTAAAATTAAAAAAGAAATTACAGTAAAAAAGAAAGTAGGACGAAAGCCAAAAATTGAAATCGATGAAAAACTAATAACTATTAAGGAACCAATGGAAATTTGCAAAATAGACGAGCAACCAGTTTTGACAAGTTCAAGTGGTCGAATTATTAAAAGAAAACTTCCAAATGTTTTTCCACAACTTCCTTATCGTCCCAGCAACATTCAAAGGCGAAGCAATGATGTTTTTGTTTGTGACGTTTGTGGACAAAAAATGGAAACTAAAGCGAGTCTCACATCACACTTATCGACTCATTACAAAGAGAAAAAGCAAAAATGTCAACATTGTAATGAATTTTTTTCAAGTGGGCAAGCACTCAAGCAACATTGTGTAAAAGAACATTTAACAAGTGAAAATTCACTTAAAGAAAAACGCTTTGAATGTGATGAATGTGGAAAACGATATATCACTTTACATCTTCTCGGAATTCACAAGAAATCACATGAAAATCTTCGCGAATATAAATGCACACATGAAGGTTGTCGGTTTGAGACAAATTCACCTTATGATCTCAAAACACACATCAAACGTATGCACAATGCGGCTAAACCATTTGAATGTCCAAATTGTGATAAGAAATTTAAAAGACGTTGTGATATGTTGAATCATAATAATTCAGTTCATAGTAATATTAAAACTTATGTCAAATGTCCTGTTTGTGCTAAAATTATTCTTGAACGAGGTCTACAAAGTCATATGATAAATCGACATTCAGAAAAGGCACAATTTAAGCCTTTTGAGTGTAGCATTTGTGGGAAAAAAGAGCGCTATGAGCGAACATTGCAAAGACATTATGATGCAGTTCATGAGCCAAAAGATCGTGGTGTTATTTATCAATGTTCTGAATGTCCTGCAAGCTTCTATAGACGACGCGAAATGAATGCACACTCATTTGAGCATTATACTGGTGAAATTTTTCAATGTTCAATATGTGAAAATAAATATAAAAGTAGAAAAGAGTTGACAAATCATGAATATAGTCATCGAGCGACTGAATATCCTTGTTCGATTTGTAATAAAGTTTTTCAAACAAAATCAGGCAGAGGAAAACATATGAAGAAGCACTATGCTAAGAAAAAAGCAGATGAAGCAACTGAAGATGATGAAGAAACAGAAGTTGATATTGATGGAGGTGAAATTGTTTATGAAGAATATGAAATTTTGGAAGAAGTTGAACAACTTGTTAACATTGAATAA
- Protein Sequence
- MSKIGQEQYLEVIQVIQQQDAVTEEIDLIEYVPEEGEGGEVVYEFVELAQPIEEIKPEIYEKNSNDTKFRCANRLCKRSNVVYDTKEELDVHNEVHIEQYRNAICPICNKELANAAKLENHIELRHTPRHFTCDQCGKVFRSKDNLRLHMSHHRKYFYVECNACGRGYKSIQSLRYHLRQHFEHHQCETCGKVFEHKKLLLGHVAAMHNQDLQVNCRYCTRTFARSDVRDTHERDIHKNGAVGSHFKCNECTETFDLRDDLMSHKILNHFSGVIHTCQECGKNFKKKSLLDLHMNVHRKKSISCDVCKQMFTFVTGLNKHKKLGRCKGPPTETLADVLTKEEIARIAKAQLQEITVNPKKEVEEEQENIEQEIKIKKEITVKKKVGRKPKIEIDEKLITIKEPMEICKIDEQPVLTSSSGRIIKRKLPNVFPQLPYRPSNIQRRSNDVFVCDVCGQKMETKASLTSHLSTHYKEKKQKCQHCNEFFSSGQALKQHCVKEHLTSENSLKEKRFECDECGKRYITLHLLGIHKKSHENLREYKCTHEGCRFETNSPYDLKTHIKRMHNAAKPFECPNCDKKFKRRCDMLNHNNSVHSNIKTYVKCPVCAKIILERGLQSHMINRHSEKAQFKPFECSICGKKERYERTLQRHYDAVHEPKDRGVIYQCSECPASFYRRREMNAHSFEHYTGEIFQCSICENKYKSRKELTNHEYSHRATEYPCSICNKVFQTKSGRGKHMKKHYAKKKADEATEDDEETEVDIDGGEIVYEEYEILEEVEQLVNIE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01250361;
- 90% Identity
- -
- 80% Identity
- -