Basic Information

Gene Symbol
Gzf1
Assembly
GCA_963422495.1
Location
OY730188.1:12221317-12232971[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 25 2.3e-05 0.0022 19.3 3.6 1 23 126 148 126 148 0.99
2 25 0.087 8.3 8.1 7.0 2 23 153 175 152 175 0.93
3 25 0.00056 0.054 15.0 1.8 1 23 181 203 181 203 0.98
4 25 4.9e-06 0.00047 21.5 1.3 1 23 209 231 209 231 0.98
5 25 4.9e-06 0.00047 21.5 1.3 1 23 250 272 250 272 0.98
6 25 4.9e-06 0.00047 21.5 1.3 1 23 291 313 291 313 0.98
7 25 0.27 26 6.5 0.7 7 23 338 354 332 354 0.85
8 25 4.9e-06 0.00047 21.5 1.3 1 23 373 395 373 395 0.98
9 25 4.9e-06 0.00047 21.5 1.3 1 23 414 436 414 436 0.98
10 25 4.9e-06 0.00047 21.5 1.3 1 23 455 477 455 477 0.98
11 25 4.2e-06 0.0004 21.7 1.6 1 23 496 518 496 518 0.98
12 25 4.9e-06 0.00047 21.5 1.3 1 23 537 559 537 559 0.98
13 25 4.9e-06 0.00047 21.5 1.3 1 23 578 600 578 600 0.98
14 25 4.9e-06 0.00047 21.5 1.3 1 23 619 641 619 641 0.98
15 25 4.9e-06 0.00047 21.5 1.3 1 23 660 682 660 682 0.98
16 25 4.9e-06 0.00047 21.5 1.3 1 23 701 723 701 723 0.98
17 25 4.9e-06 0.00047 21.5 1.3 1 23 742 764 742 764 0.98
18 25 4.9e-06 0.00047 21.5 1.3 1 23 783 805 783 805 0.98
19 25 4.9e-06 0.00047 21.5 1.3 1 23 824 846 824 846 0.98
20 25 6.3e-05 0.006 18.0 1.9 1 23 865 887 865 887 0.97
21 25 4.9e-06 0.00047 21.5 1.3 1 23 906 928 906 928 0.98
22 25 4.9e-06 0.00047 21.5 1.3 1 23 947 969 947 969 0.98
23 25 4.2e-06 0.0004 21.7 1.6 1 23 988 1010 988 1010 0.98
24 25 0.015 1.4 10.5 2.9 1 23 1016 1039 1016 1039 0.94
25 25 0.11 10 7.8 0.5 1 23 1046 1069 1046 1069 0.93

Sequence Information

Coding Sequence
ATGGCTCGGGCTGTTCGAGCGAGGCAACCACGCTGTGTACGCCCGTCCGCCTCGCTCTCGGTAAAACCGGATGATGGGTTGCCACAAAAGATCTGTAATCAGTGCTCACAGGCCCTAGAACAGGCTATTCAATTTAGAAAAACTAGCAGAAAATCTGAGAAGTCATTAATTAACTATGGACATAGAAGAAAAGAAAACAAATTTGATAAAGTAAAAAAGCCTAAATCAGAGAAAGTAGAAATTGAATTGGAACCTTCCTATGATGATTACCATGATGCCCTTGGAGGCGAGTTCTATGATCGCAGGGACGAGGGAGAAATTGCACAAAACGAGCCAGAGGTTCGGAGGAAGCCTGAGAAAGGCAAGGTGGCACAGTACCGATGCAACAAGTGCAACAAAGATTTTAAGATGAAGGCAACATACAAGGCCCACATGCGCTACCACACCAACTACTGCATGTGTGAGGCCTGCGGAAAAAGATGCAGAAACCACTATCAACTGCAGGAGCACAAACGGGCAAAACATGATCTGGGCAAAATACACAAGTGCACCTACTGCGAGTACAGCTCAGCAACTAAAGAAGCACTCACTATCCACGAGCGGCGGCACACGGGCGAGCGGCCGTACGTGTGCGACCACTGCGGCGCCACCTTCCACCGCCGCTCCAACCTCGTGCAGCACATCGCCATACACAACCCCGACAACAACTTCCAGATCCACGAGCGGCGGCACACGGGCGAGCGGCCGTACGTGTGCGACCACTGCGGCGCCACCTTCCACCGCCGCTCCAACCTCGTGCAGCACATCGCCATACACAACCCCGACAACAACTTCCAGATCCACGAGCGGCGGCACACGGGCGAGCGGCCGTACGTGTGCGACCACTGCGGCGCCACCTTCCACCGCCGCTCCAACCTCGTGCAGCACATCGCCATACACAACCCCGACAACAACTTCCAGATCCACGAGCGGCGGCACACGGGCGAGCGGCCGTACGTGTGCGACCACTTCGGCGCCACCTTCCACCGCCGCTCCAACCTCGTGCAGCACATCGCCATACACAACCCCGACAACAACTTCCAGATCCACGAGCGGCGGCACACGGGCGAGCGGCCGTACGTGTGCGACCACTGCGGCGCCACCTTCCACCGCCGCTCCAACCTCGTGCAGCACATCGCCATACACAACCCCGACAACAACTTCCAGATCCACGAGCGGCGGCACACGGGCGAGCGGCCGTACGTGTGCGACCACTGCGGCGCCACCTTCCACCGCCGCTCCAACCTCGTGCAGCACATCGCCATACACAACCCCGACAACAACTTCCAGATCCACGAGCGGCGGCACACGGGCGAGCGGCCGTACGTGTGCGACCACTGCGGCGCCACCTTCCACCGCCGCTCCAACCTCGTGCAGCACATCGCCATACACAACCCCGACAACAACTTCCAGATCCACGAGCGGCGGCACACGGGCGAGCGCCCGTACGTGTGCAACCACTGCGGCGCCACCTTCCACCGCCGCTCCAACCTCGTGCAGCACATCGCCATACACAACCCCGACAACAACTTCCAGATCCACGAGCGGCGGCACACGGGCGAGCGGCCGTACGTGTGCGACCACTGCGGCGCCACCTTCCACCGCCGCTCCAACCTCGTGCAGCACATCGCCATACACAACCCCGACAACAACTTCCAGATCCACGAGCGGCGGCACACGGGCGAGCGCCCGTACGTGTGCGACCACTGCGGCGCCACCTTCCACCGCCGCTCCAACCTCGTGCAGCACATCGCCATTCACAACCCCGACAACAACTTCCAGATCCACGAGCGGCGGCACACGGGCGAGCGGCCGTACGTGTGCGACCACTGCGGCGCCACCTTCCACCGCCGCTCCAACCTCGTGCAGCACATCGCCATACACAACCCCGACAACAACTTCCAGATCCACGAGCGGCGGCACACGGGCGAGCGGCCGTACGTGTGCGACCACTGCGGCGCCACCTTCCACCGCCGCTCCAACCTCGTGCAGCACATCGCCATACACAACCCCGACAACAACTTCCAGATCCACGAGCGGCGGCACACGGGCGAGCGGCCGTACGTGTGCGACCACTGCGGCGCCACCTTCCACCGCCGCTCCAACCTCGTGCAGCACATCGCCATACACAACCCCGACAACAACTTCCAGATCCACGAGCGGCGGCACACGGGCGAGCGCCCGTACGTGTGCGACCACTGCGGCGCCACCTTCCACCGCCGCTCCAACCTCGTGCAGCACATCGCCATACACAACCCCGACAACAACTTCCAGATCCACGAGCGGCGGCACACGGGCGAGCGCCCGTACGTGTGCGACCACTGCGGCGCCACCTTCCACCGCCGCTCCAACCTCGTGCAGCACATCGCCATACACAACCCCGACAACAACTTCCAGATCCACGAGCGGCGGCACACGGGCGAGCGGCCGTACGTGTGCGACCACTGCGGCGCCACCTTCCACCGCCGCTCCAACCTCGTGCAGCACATCGCCATACACAACCCCGACAACAACTTCCAGATCCACGAGCGGCGGCACACGGGCGAGCGCCCGTACGTGTGCGACCACTGCGGCTCCACCTTCCACCGCCGCTCCAACCTCGTGCAGCACGTCGCCATACACAACCCCGACAACAACTTCCAGATCCACGAGCGGCGGCACACGGGCGAGCGGCCGTACGTGTGCGACCACTGCGGCGCCACCTTCCACCGCCGCTCCAACCTCGTGCAGCACATCGCCATACACAACCCCGACAACAACTTCCAGATCCACGAGCGGCGGCACACGGGCGAGCGCCCGTACGTGTGCGACCACTGCGGCGCCACCTTCCACCGCCGCTCCAACCTCGTGCAGCACATCGCCATACACAACCCCGACAACAACTTCCAGATCCACGAGCGGCGGCACACGGGCGAGCGCCCGTACGTGTGCAACCACTGCGGCGCCACCTTCCACCGCCGCTCCAACCTCGTGCAGCACATCGCCATACACAACCCCGACAACAACTTCCAGTGCGACATGTGCCCGAAGCGGCTGAAGTCGCGCAAGTTCCTGCAGATCCACAAGCACAACGCGCACACCGGCCGCCGCTACGGATACCTGTGCGGCGCCTGCGGACACCGCTTCGACAAACCCAACAAGgtTCGCGCGCACGCCCGCCGCGTCCACGCGCTGCCCGACGAACGCCAGCCGCCCGTTGTGCGCGTGCAGCTGTAG
Protein Sequence
MARAVRARQPRCVRPSASLSVKPDDGLPQKICNQCSQALEQAIQFRKTSRKSEKSLINYGHRRKENKFDKVKKPKSEKVEIELEPSYDDYHDALGGEFYDRRDEGEIAQNEPEVRRKPEKGKVAQYRCNKCNKDFKMKATYKAHMRYHTNYCMCEACGKRCRNHYQLQEHKRAKHDLGKIHKCTYCEYSSATKEALTIHERRHTGERPYVCDHCGATFHRRSNLVQHIAIHNPDNNFQIHERRHTGERPYVCDHCGATFHRRSNLVQHIAIHNPDNNFQIHERRHTGERPYVCDHCGATFHRRSNLVQHIAIHNPDNNFQIHERRHTGERPYVCDHFGATFHRRSNLVQHIAIHNPDNNFQIHERRHTGERPYVCDHCGATFHRRSNLVQHIAIHNPDNNFQIHERRHTGERPYVCDHCGATFHRRSNLVQHIAIHNPDNNFQIHERRHTGERPYVCDHCGATFHRRSNLVQHIAIHNPDNNFQIHERRHTGERPYVCNHCGATFHRRSNLVQHIAIHNPDNNFQIHERRHTGERPYVCDHCGATFHRRSNLVQHIAIHNPDNNFQIHERRHTGERPYVCDHCGATFHRRSNLVQHIAIHNPDNNFQIHERRHTGERPYVCDHCGATFHRRSNLVQHIAIHNPDNNFQIHERRHTGERPYVCDHCGATFHRRSNLVQHIAIHNPDNNFQIHERRHTGERPYVCDHCGATFHRRSNLVQHIAIHNPDNNFQIHERRHTGERPYVCDHCGATFHRRSNLVQHIAIHNPDNNFQIHERRHTGERPYVCDHCGATFHRRSNLVQHIAIHNPDNNFQIHERRHTGERPYVCDHCGATFHRRSNLVQHIAIHNPDNNFQIHERRHTGERPYVCDHCGSTFHRRSNLVQHVAIHNPDNNFQIHERRHTGERPYVCDHCGATFHRRSNLVQHIAIHNPDNNFQIHERRHTGERPYVCDHCGATFHRRSNLVQHIAIHNPDNNFQIHERRHTGERPYVCNHCGATFHRRSNLVQHIAIHNPDNNFQCDMCPKRLKSRKFLQIHKHNAHTGRRYGYLCGACGHRFDKPNKVRAHARRVHALPDERQPPVVRVQL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01248366;
90% Identity
iTF_01248366;
80% Identity
iTF_01248366;