Pfla009417.1
Basic Information
- Insect
- Polymixis flavicincta
- Gene Symbol
- -
- Assembly
- GCA_949987655.1
- Location
- OX465175.1:8573156-8581187[-]
Transcription Factor Domain
- TF Family
- HMGA
- Domain
- HMGA domain
- PFAM
- AnimalTFDB
- TF Group
- Unclassified Structure
- Description
- This entry represents the HMGA family, whose members contain DNA-binding domains, also known as AT hooks due to their ability to interact with the narrow minor groove of AT-rich DNA sequences. They play an important role in chromatin organisation [1]. The high mobility group (HMG) proteins are the most abundant and ubiquitous nonhistone chromosomal proteins. They bind to DNA and to nucleosomes and are involved in the regulation of DNA-dependent processes such as transcription, replication, recombination, and DNA repair. They can be grouped into three families: HMGB (HMG 1/2), HMGN (HMG 14/17) and HMGA (HMG I/Y). The characteristic domains are: AT-hook for the HMGA family, the HMG Box for the HMGB family, and the nucleosome-binding domain (NBD) for the members of the HMGN family [2].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 0.031 1.5e+03 0.4 3.2 11 16 13 18 11 19 0.82 2 4 0.6 3e+04 -3.8 2.2 12 15 33 36 33 36 0.96 3 4 1.9e-09 9.2e-05 23.4 3.7 4 22 53 71 51 71 0.89 4 4 1 4.9e+04 -6.0 6.9 10 15 83 88 82 89 0.83
Sequence Information
- Coding Sequence
- ATGTCTGATGACGGATCCACGGTGGTAGAGAAGAAAGGACGCGGTAGACCGAAAGCCAATGGAACACAATCGGAGGCTAAGAGTGATACCAAGAAAAGGGGGAGACCACCGGCACCCACCAGGACTAAGGAATCCACAAAGTCATCGGATGATGAACAAGCTCCAGTAGCAAAACGAGGGCGAGGCAGGCCTAAGGGATCCAAGAAAAAGTCAGCTGCTAAAGGAAAgAGTGCACCAGTTGAAGGAAGGGGCCGTGGACGACCACGCAAGGACCCGCCACCTAAGAAAGATGCTGCCTCCACTGAAGAGGAACAGGATGATGATTATGAGGATGAAGGCTCTGAGGAGCAGTACTATACCGATAGAAAGACACCTGTATATGCTGCTTTCTtggacctctccaaggcatttgacctGGTTGATTATAGTATCTTATGGTCGAAATTGCGTGAGCAAGGTCTTCCTAATGAGCTCATTAAGCTCTTAGACTACTGGTATGGCCATCAAATCAACCAGGTCAGATGGTCGGGGGCTGTGTCTGGGGCGTTTGGGTTGGAGTGTGGGGTGAGACAGGGTGGTTTGACTTCCCCGGCGCTCTTCAGTCTATACGTCAATAAGTTGATAGAGGACCTCAGCAGCACTGGTATAGGATGCTCTGTTGATGGTCACATTATTAACAGTATAAGTTATGCTgatgatatggtgctgctgagtccCTCGATTGACGGACTCAGACGGATGCTTGAGGTATGCGAGAGATACGCCACGTCTCATGGTTTAGTGTACAATGTACGGAAAAGTGAACTGGTGGTATTTAGGGTAGGGACTAAAAAGCCAAGAGAAGTTCCTCCGGTGTTTCTTTATGGTGTACCACTGAAGCGAGTGTCGCAGTTTAAGTACCTCGGTCACATAATAAATGAGGACCTGAGTGATGACAGTGACATTGAAAGGGAGCGAAGAGCGTTGTCGATCCGCTGTAATATGCTGGCCCGTAGGTTTGCGCGATGTACTAGGGAAGTGAAACTCACTCTGTTCAAGGCGTTTTGCCAGTCATTTTACacatgcagcctgtgggttaggCATACGCAGAGGGTCTACAACGTTCTACGCGTACAGTACAATAACGCCTTTAGGGTGCTGATGGGGCTTCCGCGGTTCTGTAGCGCATCGggcatgtttgctgaagctAATACAGACAGCTTTCAAGCTATTATGCGCAAAAGATCAGCATCCCTGATGCGAAGGATTCGCGGGAGCACCAACAGCATCCTAAAGGTGATAGTGAATAAGCCTGATTGCCCGTTCCTGGTGCACTGGACCAGTATGCACAGCTGCAGGTCTGGTGCAGCGGGAAACGCAGATAGTAATTATAATAGGTTTATGAATTAG
- Protein Sequence
- MSDDGSTVVEKKGRGRPKANGTQSEAKSDTKKRGRPPAPTRTKESTKSSDDEQAPVAKRGRGRPKGSKKKSAAKGKSAPVEGRGRGRPRKDPPPKKDAASTEEEQDDDYEDEGSEEQYYTDRKTPVYAAFLDLSKAFDLVDYSILWSKLREQGLPNELIKLLDYWYGHQINQVRWSGAVSGAFGLECGVRQGGLTSPALFSLYVNKLIEDLSSTGIGCSVDGHIINSISYADDMVLLSPSIDGLRRMLEVCERYATSHGLVYNVRKSELVVFRVGTKKPREVPPVFLYGVPLKRVSQFKYLGHIINEDLSDDSDIERERRALSIRCNMLARRFARCTREVKLTLFKAFCQSFYTCSLWVRHTQRVYNVLRVQYNNAFRVLMGLPRFCSASGMFAEANTDSFQAIMRKRSASLMRRIRGSTNSILKVIVNKPDCPFLVHWTSMHSCRSGAAGNADSNYNRFMN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -