Basic Information

Insect: Polydrusus cervinus
Gene Symbol: topi
Assembly: GCA_935413225.1
Location: CAKXYS010000185.1:44703-51717[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0034 0.35 12.7 2.4 2 21 97 116 96 117 0.94

2 14 2.2e-05 0.0023 19.6 0.5 1 23 146 168 146 168 0.95

3 14 0.0088 0.91 11.4 1.6 2 23 175 196 175 196 0.95

4 14 0.21 22 7.1 0.3 2 12 215 225 214 232 0.87

5 14 1.6e-05 0.0016 20.0 1.9 2 23 288 309 287 309 0.97

6 14 0.098 10 8.1 0.2 1 20 315 334 315 336 0.85

7 14 0.1 10 8.1 2.6 2 21 352 371 351 375 0.84

8 14 6.2 6.3e+02 2.4 1.6 1 23 492 515 492 515 0.91

9 14 0.19 19 7.2 1.2 1 23 519 541 519 541 0.91

10 14 1.2e-06 0.00012 23.6 2.4 1 23 547 569 547 569 0.98

11 14 0.033 3.4 9.6 0.2 1 23 575 600 575 600 0.96

12 14 0.21 22 7.1 3.3 1 23 606 628 606 628 0.86

13 14 4.3e-05 0.0045 18.7 1.6 3 23 636 656 634 656 0.97

14 14 8.3e-06 0.00086 20.9 0.6 1 23 662 685 662 685 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0034	0.35	12.7	2.4	2	21	97	116	96	117	0.94
2	14	2.2e-05	0.0023	19.6	0.5	1	23	146	168	146	168	0.95
3	14	0.0088	0.91	11.4	1.6	2	23	175	196	175	196	0.95
4	14	0.21	22	7.1	0.3	2	12	215	225	214	232	0.87
5	14	1.6e-05	0.0016	20.0	1.9	2	23	288	309	287	309	0.97
6	14	0.098	10	8.1	0.2	1	20	315	334	315	336	0.85
7	14	0.1	10	8.1	2.6	2	21	352	371	351	375	0.84
8	14	6.2	6.3e+02	2.4	1.6	1	23	492	515	492	515	0.91
9	14	0.19	19	7.2	1.2	1	23	519	541	519	541	0.91
10	14	1.2e-06	0.00012	23.6	2.4	1	23	547	569	547	569	0.98
11	14	0.033	3.4	9.6	0.2	1	23	575	600	575	600	0.96
12	14	0.21	22	7.1	3.3	1	23	606	628	606	628	0.86
13	14	4.3e-05	0.0045	18.7	1.6	3	23	636	656	634	656	0.97
14	14	8.3e-06	0.00086	20.9	0.6	1	23	662	685	662	685	0.98

Sequence Information

Coding Sequence: ATGAATAATACTGTGGTtattttaattcacaaaataGTAGACGGCCAAATTGTTTCAACGATTAGAGatgaaaaaaatgcaagttcTGCACTGGATATGGTAATGCGTACTTTTCTTAGCTCAGATGATGCatattttgattttcaaaattaCGATGAAAACAAGTTAAGCTTAAATATTAGTCATACAGAGTCAGACGATTCAATAACAATTGAAGCCTTAGAGAGCCTAGAGTTATCAACAAATAATCCAGATTCAATGGTAAGATTAAATTTTCCAACATTAATAAAGTGCCAAAATTGCGAAACAAATTTTCCGACAAAATATCAGTACCAAAGACACCAATGCGATTTTAATTCGGAAAAGGTTGTTTTCAAATCATCTCCGGAAAACTTATCTGGTATAGAGAACAATGAAGAAAATGAAAAACCTGTATTTGAATGTCcgatatgttttaaattttttgctaataAAAATAACCTAGATCGACATCAGGTTGGTCATAATAATAACAATGACAACGTTTGCGAGTTTTGCGGTAAACATTTTGTCAGCGAAAACCGTCTGCGTATTCATAAGGAAAACCACTGCAAAAAAGCCGGAGATATTTCCAAATTTTATAGAAGTGATGTAACAGTTTGGAAATGCAAAAAATGCCACGAAGTTTTTTCTTCCCTTCAGATTGCGAACCACCACGTTCCACTTTGTCACGAAATTCTCGAAGTGCAAGGAAATGATCAAGCCGATAAGGAAAATGTAGAAGCGGTACTCCAAGATGATACATTTAATAATGATCCGGGATATTCAAAGCCCAATCAATTAGATAAATATACTGAAGCAATTTTAACGGAAATTTTACTTCAATGCGAATTTTGTAACAGAACTTTTTCGGACAAAAACTTGTTGCTAATGCATCAACGAAAGCATACGACAGCTAAAAATTACGAATGCGTAAATTGTAATAAAGTATTCGATTCATATACCACGGCATCTTCTCACTGGTTAAAGAGATGTTCCGACTAtgccaatttattttatttgcccaAACTATCTTATTGCGAGTATTGCGATAGAACTTTTAAATCGCACGAAATTTTATacaatcataaaattaaaaagaagcaTTATACTCCAAAGTTACATATTGCTGTAAATGTTGAACCAGACAATGTGCATGATGAACCGAAATCTGCTCCAGAAAACaaagatattataaataaacttattcAAGATGTTTTAAAAACATTGGAAGTTCCTGTAATAAACAAGGGAAATAATGAAAAAGACAATATTTACGCCGATTCCGAtgtaacaattattaatataaaaactgaACCGGATAGTGGAAATACAAAACAAAATATTGACAATCAGGAAGCAGAAATAACCAGAAGACCTGGTAAAAAACGCAGATGGCATAAAAGTatgacaaaaagtaaaaaatactgTATAACTACAGATGAAGGCTTTAAATATCAATGCGAGCGATGCATCAAAGTTTTTAATTGCATCGTTAGTTTAGAGACCCACAGGACTAGCGAGCATGTGGCTACTTTTTGCTGCGAGGAGTGTGGTCAGacCCTTGGAAGCGCTAAGGCATTGCTTATTCATTGCAGAGCCCATAAAAGTTTAAAACCGTACGTATGCGATACCTGCGGCAGAAGTTACTCACAGACTTCTCATCTCTGGCAACATATGCGATTCCATCAGGGAATCAAGCCCTTTGCTTGTCCACATGAAGGTTGTGAAGCCAGATACACTATAAGACCAGATCTTAAGGACCACATTCGTAAAGTGCATACAAGAGAACGTCCTTTCAAATGTAATGTTTGCAATAAATGCTTTTTGACCGGCTCTGTATATTACCAGCACAGATTGATTCATACAAACGATAGAAGATATGGATGTGAGatttgcCATAAGAGATTTTTTAGAGCAGATGCTTTAAATAACCACAAACGAATTCATACAGATGAAAGACCTTATCCGTGCAGTGTTTGTGGAAGAGAGTTTAGACAAAAGGGGGATCGAAACAAACACGTCCGTACCCAACATCCTGATTATTTTAGTTCCAATGTTTAA
Protein Sequence: MNNTVVILIHKIVDGQIVSTIRDEKNASSALDMVMRTFLSSDDAYFDFQNYDENKLSLNISHTESDDSITIEALESLELSTNNPDSMVRLNFPTLIKCQNCETNFPTKYQYQRHQCDFNSEKVVFKSSPENLSGIENNEENEKPVFECPICFKFFANKNNLDRHQVGHNNNNDNVCEFCGKHFVSENRLRIHKENHCKKAGDISKFYRSDVTVWKCKKCHEVFSSLQIANHHVPLCHEILEVQGNDQADKENVEAVLQDDTFNNDPGYSKPNQLDKYTEAILTEILLQCEFCNRTFSDKNLLLMHQRKHTTAKNYECVNCNKVFDSYTTASSHWLKRCSDYANLFYLPKLSYCEYCDRTFKSHEILYNHKIKKKHYTPKLHIAVNVEPDNVHDEPKSAPENKDIINKLIQDVLKTLEVPVINKGNNEKDNIYADSDVTIINIKTEPDSGNTKQNIDNQEAEITRRPGKKRRWHKSMTKSKKYCITTDEGFKYQCERCIKVFNCIVSLETHRTSEHVATFCCEECGQTLGSAKALLIHCRAHKSLKPYVCDTCGRSYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFKCNVCNKCFLTGSVYYQHRLIHTNDRRYGCEICHKRFFRADALNNHKRIHTDERPYPCSVCGREFRQKGDRNKHVRTQHPDYFSSNV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00444443;
90% Identity: -
80% Identity: -