Basic Information

Insect: Diaprepes abbreviatus
Gene Symbol: topi
Assembly: GCA_034092305.1
Location: JASJET010000122.1:20919868-20931142[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0034 0.48 12.6 2.3 2 21 96 115 95 116 0.94

2 14 6.1e-06 0.00086 21.3 0.2 1 23 145 167 145 167 0.96

3 14 0.012 1.7 10.9 1.6 3 23 175 195 174 195 0.95

4 14 0.13 19 7.6 0.5 2 13 214 225 213 231 0.86

5 14 1.6e-05 0.0023 19.9 1.9 2 23 287 308 286 308 0.97

6 14 0.022 3.1 10.1 0.2 1 20 314 333 314 335 0.91

7 14 0.1 15 8.0 2.6 2 21 351 370 350 374 0.84

8 14 4.9 7e+02 2.7 0.4 1 23 534 557 534 557 0.85

9 14 0.19 27 7.1 1.2 1 23 561 583 561 583 0.91

10 14 1.2e-06 0.00017 23.5 2.4 1 23 589 611 589 611 0.98

11 14 0.034 4.8 9.5 0.2 1 23 617 642 617 642 0.96

12 14 0.21 30 7.0 3.3 1 23 648 670 648 670 0.86

13 14 4.4e-05 0.0062 18.6 1.6 3 23 678 698 676 698 0.97

14 14 8.4e-06 0.0012 20.8 0.6 1 23 704 727 704 727 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0034	0.48	12.6	2.3	2	21	96	115	95	116	0.94
2	14	6.1e-06	0.00086	21.3	0.2	1	23	145	167	145	167	0.96
3	14	0.012	1.7	10.9	1.6	3	23	175	195	174	195	0.95
4	14	0.13	19	7.6	0.5	2	13	214	225	213	231	0.86
5	14	1.6e-05	0.0023	19.9	1.9	2	23	287	308	286	308	0.97
6	14	0.022	3.1	10.1	0.2	1	20	314	333	314	335	0.91
7	14	0.1	15	8.0	2.6	2	21	351	370	350	374	0.84
8	14	4.9	7e+02	2.7	0.4	1	23	534	557	534	557	0.85
9	14	0.19	27	7.1	1.2	1	23	561	583	561	583	0.91
10	14	1.2e-06	0.00017	23.5	2.4	1	23	589	611	589	611	0.98
11	14	0.034	4.8	9.5	0.2	1	23	617	642	617	642	0.96
12	14	0.21	30	7.0	3.3	1	23	648	670	648	670	0.86
13	14	4.4e-05	0.0062	18.6	1.6	3	23	678	698	676	698	0.97
14	14	8.4e-06	0.0012	20.8	0.6	1	23	704	727	704	727	0.98

Sequence Information

Coding Sequence: ATGAATAACACTGTGGTGattttaattcacaaaatagtAGACGGCGAAATTGTATCGACGATACGAGATGAAAAAAATGCAAGTTCTGCGTTAGATATGGTAATGCGTACTTTTCTTAGCGCTGAAGATGCacactttgatttaaaaaaatacgatgAGAATAAATTAAGTTTGAATATCGGTCAATCTGATCTAGATGATTCCATAACAATCGAGACATTAGGCACGGATTCAACTGTGATTAATTCAGAATCTTTGGTAAGACTTAATTTTCCAACACTAATAAAATGCCAAAATTGTGAAACCAATTTTCCAACAAAATATCAATACCAAAGACATCAATGCGATTTTAATTCAGAAAAAGTTCTTTTTAAATCTTCTACGGATGATATGACTAGTATGGAAAATGATGAGGAAAATAAAAAACCTACATTTGAATGTCCagtatgttttaaagtttttgcaaataaaaataatttagatcgtCATCAGATTGGTCATAACAATAACAATGATAATATTTGCGAATTTTGCGGTAAACATTTTGTTAGCGAAAACCGTTTACGAATACATAAAGAAAACCATTGCAAAAAAGCTGGTGATATTTCTAAGTTTTATAGAAGTGACGTAACAGTCTGGAAGTGCAAAAAATGCCACGAGGTTTTTTCTTCACCTCAAATAGCAAATCATCACGTCCCGCTTTGTCAAGAAATTCTCGATGTAGGGAATGATCATTCTGATaaggaaaatattgaaatagAACTCCAAGATGACAATTTAAACGACGAATCTGGATACTCTAAATCCAATACCTTCGTTAACAAATGTACTGAAACAATTTTAACAGAAATTTTGCTTCAATGTGAGTTTTGTAACAGGACATTTTCGGACAAAAATCTCTTGCTAATGCACCAACGGAAACATACTACAGCAAAAAATTATGAATGTGTAAATTGCAATAAAGTTTTCGATTCTTATTCTTCTGCATCATCTCACTGGCTAAAAAAATGTTCTGAATTTGCAAACTTGTTTTATTTGCCGAAACTGTCTTATTGCGAATATTGCGATAGAACATTCAAATCTCATGAAATTCTTTACaaccataaaattaaaaagaagcaTTATACTCCAAAGTTACATATAGCTGTAAACGTTGAACCAGATGACGTTCATGATGAACCAAAACCTACACCAGaaaataaggatattattaataaattaatacaggatgttttaaagaCATTAGAAGTTCCAGTAACACCCAAAACCAATGGCGAAAATGGAAATAACAGTTGCGGAAATGCTAGTACTGATATTtccattattaatattaaaactgaaccAGACAGTGGAAATACAAGCAGGCAAGTAGAGGTATTAAATACAAGACTTTTCTGGGTCAAAGCAAGGCCTAACAGAGCAAACAAACTCtgccaaaacaaaatatattttggtaaaaaattactAAATACTAGCACCCATCAAAATGATGAAGTTCAAGACGACGAAACGAATAATAAATCTGGTAAAAAACGAAAGTGGCACAAAAGTacgacaaaaagtaaaaaatattgcatAACTACGGACGAAGGTTTTAAATATCAATGTGAAAGATGTATCAAAGTGTTTAATTGCATTGTAAGTTTAGAAGCCCACAGAGCTGGTGAACACGTAGCTACTTTTTGTTGCGAGGAGTGTGGTCAGACACTCGGAAGTGCCAAAGCTTTACTTATCCATTGTCGGGCCCACAAGAGTTTAAAACCATATGTTTGTGATACCTGTGGTAGAAGTTACTCTCAGACTTCACACCTATGGCAACACATGAGATTTCATCAAGGAATCAAACCATTTGCTTGTCCTCATGAAGGTTGTGAAGCAAGATATACTATTAGACCAGATCTCAAAGATCATATTCGTAAAGTTCATACAAGAGAACGCCCTTTTAAATGTAATGTTTGTAACAAATGTTTTTTGACTGGTTCTGTGTATTATCAACACAGGCTGATACACACTAACGATAGAAGATATGGATGTGAGatttgccATAAAAGGTTCTTTAGAGCTGATGCTCTAAACAATCACAAAAGAATTCATACAGATGAAAGACCTTATCCATGCAGCGTTTGTGGGAGAGAATTTCGACAAAAAGGTGATCGAAATAAACATGTCCGCACCCAACATCCTGATTATTTTAGTTcaaacatataa
Protein Sequence: MNNTVVILIHKIVDGEIVSTIRDEKNASSALDMVMRTFLSAEDAHFDLKKYDENKLSLNIGQSDLDDSITIETLGTDSTVINSESLVRLNFPTLIKCQNCETNFPTKYQYQRHQCDFNSEKVLFKSSTDDMTSMENDEENKKPTFECPVCFKVFANKNNLDRHQIGHNNNNDNICEFCGKHFVSENRLRIHKENHCKKAGDISKFYRSDVTVWKCKKCHEVFSSPQIANHHVPLCQEILDVGNDHSDKENIEIELQDDNLNDESGYSKSNTFVNKCTETILTEILLQCEFCNRTFSDKNLLLMHQRKHTTAKNYECVNCNKVFDSYSSASSHWLKKCSEFANLFYLPKLSYCEYCDRTFKSHEILYNHKIKKKHYTPKLHIAVNVEPDDVHDEPKPTPENKDIINKLIQDVLKTLEVPVTPKTNGENGNNSCGNASTDISIINIKTEPDSGNTSRQVEVLNTRLFWVKARPNRANKLCQNKIYFGKKLLNTSTHQNDEVQDDETNNKSGKKRKWHKSTTKSKKYCITTDEGFKYQCERCIKVFNCIVSLEAHRAGEHVATFCCEECGQTLGSAKALLIHCRAHKSLKPYVCDTCGRSYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFKCNVCNKCFLTGSVYYQHRLIHTNDRRYGCEICHKRFFRADALNNHKRIHTDERPYPCSVCGREFRQKGDRNKHVRTQHPDYFSSNI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01239450;
90% Identity: -
80% Identity: -